• Title/Summary/Keyword: chemical standardization

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Standardization of Terminology Relating to Biotechnology and Bioindustry

  • Chang, Yong-Keun;Kim, Jin-Hyun;Chae, Hee-Jeong;Park, Hyun-Gyu;Na, Jeong-Geol
    • 한국생물공학회:학술대회논문집
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    • 2003.10a
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    • pp.79-83
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    • 2003
  • Standard terms on biotechnology, bioprodutcs and related services are essential for clear and consistent communications and information exchange among peoples working in the area of biotechnology and bioindustry. The standardization of biotechnology terms are prerequisite to any other standardization efforts in the area. The major objective of this project is to develop a comprehensive and advanced terminology platform for the legislation of KS codes for the domestic bioindustry by data mining from various sources.

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Chemical Standardization of Phellinus Species (상황의 이화학적 규격 연구)

  • Cho, Min-Jung;Park, Mi-Jung;Kim, Young-Choong;Ze, Keum-Ryon;Lee, Heum-Sook
    • Korean Journal of Pharmacognosy
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    • v.36 no.2 s.141
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    • pp.65-69
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    • 2005
  • The extract contents of various Phellinus species (Hymenochaetaceae) including P. linteus, P. baumii, P. pini and P. igniarius of domestic and foreign products, were examined to standardize the quality of these products. The differences of various extract contents were identified and compared between different species of Phellinus products. The thin layer chromatographic patterns were also analyzed and six unidentified samples were thought to originate from P. baumii and P. igniarius. The chemical standardization for the quality control of various origins could be suggested by this study.

ISO/TC107 - Metallic and other inorganic coatings: Involvement, Activities and Standardization

  • Gyawali, Gobinda
    • Proceedings of the Korean Institute of Surface Engineering Conference
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    • 2017.05a
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    • pp.85-85
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    • 2017
  • ISO (International Organization for Standardization) is an independent, non-governmental international organization with a membership of 163 national standards bodies (NSB). The ISO standards are developed and processed within the technical committees (TC) or their subcommittees (SC) dealing with the different subject matters. The first technical committee, ISO/TC1, deals with screw threads and was created back in 1947. While, more recently, TC 309 was created to standardize organizational governance. The ISO technical committee in the field of metallic coatings was created in 1962 with the title ISO/TC107- Metallic and other inorganic coatings. This ISO/TC107 technical committee is dealing with the standardization of the characteristics of protective and decorative metallic coatings applied by electrolysis, fusion, vacuum or chemical means, mechanical deposition and ion plating. similarly, it also covers the standardization of the characteristics of protective and decorative non-metallic coatings (excluding paints and other organic coatings) on metal surface applied by electrolysis, fusion, vacuum or chemical means. Scope is further extended to the Standardization of the preparation of the substrates prior to the deposition of metallic and inorganic coatings. There are a total of 144 existing ISO standards published by this technical committee and has 19 participating countries (P-members) and 24 observing countries (O-members). Korean Agency for Technology and Standards (KATS), being the secretariat of ISO/TC107, is constantly supporting this technical committee for the development of standards and related activities.

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Chemical transformation and target preparation of saponins in stems and leaves of Panax notoginseng

  • Wang, Ru-Feng;Li, Juan;Hu, Hai-Jun;Li, Jia;Yang, Ying-Bo;Yang, Li;Wang, Zheng-Tao
    • Journal of Ginseng Research
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    • v.42 no.3
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    • pp.270-276
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    • 2018
  • Background: Notoginsenoside Ft1 is a promising potential candidate for cardiovascular and cancer disease therapy owing to its positive pharmacological activities. However, the yield of Ft1 is ultralow utilizing reported methods. Herein, an acid hydrolyzing strategy was implemented in the acquirement of rare notoginsenoside Ft1. Methods: Chemical profiles were identified by ultraperformance liquid chromatography coupled with quadruple-time-of-flight and electrospray ionization mass spectrometry (UPLC-Q/TOF-ESI-MS). The acid hydrolyzing dynamic changes of chemical compositions and the possible transformation pathways of saponins were monitored by ultrahigh-performance LC coupled with tandem MS (UHPLC-MS/ MS). Results and conclusion: Notoginsenoside Ft1 was epimerized from notoginsenoside ST4, which was generated through cleaving the carbohydrate side chains at C-20 of notoginsenosides Fa and Fc, and vinaginsenoside R7, and further converted to other compounds via hydroxylation at C-25 or hydrolysis of the carbohydrate side chains at C-3 under the acid conditions. High temperature contributed to the hydroxylation reaction at C-25 and 25% acetic acid concentration was conducive to the preparation of notoginsenoside Ft1. C-20 epimers of notoginsenoside Ft1 and ST4 were successfully separated utilizing solvent method of acetic acid solution. The theoretical preparation yield rate of notoginsenoside Ft1 was about 1.8%, which would be beneficial to further study on its bioactivities and clinical application.

A Review on Quality Control of Korean Medicinal Herbs Through Packaging Standardization (국내 한약재의 유통상 품질 문제점과 포장표준화를 통한 대응방안 고찰)

  • Kah, Jin-Dong;Kim, Jai-Neung;Park, Su-Il;Lee, Youn-Suk
    • KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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    • v.13 no.2
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    • pp.43-50
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    • 2007
  • The production, distribution, and consumption of Korean medicinal herbs have increased every year because of an increase of health considerations. But there are no sufficient standardization procedures in packaging and distribution systems related to these herb products. The standardization of packaging material and dimension could be a good addition for establishing proper quality control methods for Korean medicinal herbs. Medicinal herbs deteriorate under physical, chemical and biological hazards such as oxidation, textural change under high moisture content, color change by light, sanitation problems by insect invasion and contamination. Packaging standardization with proper functional packaging materials is critical to ensure the qualities of medicinal herbs. Also, storage and distribution efficiencies can be improved by achieving packaging dimension standardization. This review summarizes recent research trends related to quality evaluation methods and major quality deterioration factors of Korean medicinal herbs. This paper also offers reviews on some of problems and challenges in current packaging and distribution systems of medicinal herb industries and briefly suggests advanced quality control methods through packaging standardization.

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The Standardization and effect analysis of core business process of the digital production information management system (integrated POP system) through case construction of chemical manufacturing industry (화학제조업의 사례구축을 통한 디지털 생산정보관리시스템 (통합 POP 시스템) 핵심 업무 프로세스 표준화 및 효과분석)

  • Kim, ChiGon;Kwon, HeeChoul;Zun, Hyungdo;Yoon, KyungBae
    • The Journal of the Convergence on Culture Technology
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    • v.3 no.3
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    • pp.43-49
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    • 2017
  • The purpose of this study is to study the standardization of the core business process in the chemical manufacturing industry and to establish a production information management system for the purpose of establishing the production information management system that can achieve mid -To be applied. The development methodology for the standardization of the chemical manufacturing information system is applied to the production information management system development methodology (PSDM) that was developed and developed by the Agency for Technology and Information Promotion of Small and Medium Enterprises. The standardization target is the system structure, It is a core business process that becomes a skeleton during construction. In this study, the chemical manufacturing SMEs and related professional IT companies who want to build the production information management system can apply the standardized core business process more effectively to build the system more effectively, and provide ease of installation and reliability to the system, In order to maximize the utilization of processes, follow-up education training and maintenance measures are suggested. Applying the results of this study, it is possible to eliminate the unreasonable elements of the production process, improve the quality of production product, and reduce production cost.

Dammarane-type triterpene oligoglycosides from the leaves and stems of Panax notoginseng and their antiinflammatory activities

  • Li, Juan;Wang, Ru-Feng;Zhou, Yue;Hu, Hai-Jun;Yang, Ying-Bo;Yang, Li;Wang, Zheng-Tao
    • Journal of Ginseng Research
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    • v.43 no.3
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    • pp.377-384
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    • 2019
  • Background: Inflammation is widespread in the clinical pathology and closely associated to the progress of many diseases. Triterpenoid saponins as a key group of active ingredients in Panax notoginseng (Burk.) F.H. Chen were demonstrated to show antiinflammatory effects. However, the chemical structures of saponins in the leaves and stems of Panax notoginseng (PNLS) are still not fully clear. Herein, the isolation, purification and further evaluation of the antiinflammatory activity of dammarane-type triterpenoid saponins from PNLS were conducted. Methods: Silica gel and reversed-phase C8 column chromatography were used. Furthermore, preparative HPLC was used as a final purification technique to obtain minor saponins with high purities. MS, NMR experiments, and chemical methods were used in the structural identifications. The antiinflammatory activities of the isolated saponins were assessed by measuring the nitric oxide production in RAW 264.7 cells stimulated by lipopolysaccharides. Real-time reverse transcription polymerase chain reaction was used to measure the gene expressions of inflammation-related gene. Results: Eight new minor dammarane-type triterpene oligoglycosides, namely notoginsenosides LK1-LK8 (1-8) were obtained from PNLS, along with seven known ones. Among the isolated saponins, gypenoside IX significantly suppressed the nitric oxide production and inflammatory cytokines including tumor necrosis $factor-{\alpha}$, interleukin 10, interferon-inducible protein 10 and $interleukin-1{\beta}$. Conclusion: The eight saponins may enrich and expand the chemical library of saponins in Panax genus. Moreover, it is reported for the first time that gypenoside IX showed moderate antiinflammatory activity.

Necessity of Standardization and Standardized Method for Substances Accounting of Environmental Liability Insurance (환경책임보험 배출 물질 정산의 표준화 필요성 및 산출방법 표준화)

  • Park, Myeongnam;Kim, Chang-wan;Shin, Dongil
    • Journal of the Korean Institute of Gas
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    • v.22 no.5
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    • pp.1-17
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    • 2018
  • Related incidents and accidents are frequent after 2000 years, such as the outbreak of the Taian peninsula crude oil spillage and Gumi hydrofluoric acid leakage accident. In the wake of such environmental pollution accidents, Consensus has been formed to enact legislation on liability for the compensation of environmental pollution in 2014 and the rescue, and has been in force since January 2016. Therefore, in the domestic insurance industry, the introduced environmental liability insurance system needs to be managed through the standardization formula of a new insurance model for managing the environmental risk. This study has been carried out by the emergence of a safe insurance model with a risky nature of the risk type, which is one of the services of the knowledge base. The verification of the six assurance media on the occurrence of environmental pollution such as chemical, waste, marine, soil, etc. is expressed through semantic interoperability through this possible ontology. The insurance model was designed and presented by deducing the relationship between the amount of money and the amount of money that was written in the area of existing expertise, In order to exclude the possible consequences, the concept of abstract is conceptualized in the form of a customer, and a plan for the future development of an ontology-based decision support system is proposed to reduce the cost and resources consumed every year. It is expected that standardization of the verification standard of the mass of mass will minimize errors and reduce the time and resources required for verification.