• Journal of the Society of Naval Architects of Korea
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• v.29 no.1
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• pp.55-60
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• 1992

A study has been made on the hydrodynamic forces on and the motion response of a sliding block in a bay within the framework of linear potential theory. To simplify the problem, following assumptions are made : The configuration of the bay is a long channel with narrow width, constant depth and straight coastline. Incident waves are long compared to the depth. We applied matched asymptotic expansion techniques. The flued domain is subdivided into three regions ; ocean, bay entrance, bay regions. Boundary-vague problems are solved first in each region. Then unknown coefficients are determined by matching individual solutions at the intermediate region between two neighboring legions. It is found that the motion of the block is greatly amplified at the resonant frequencies, in particular at the quarter wavelength mode. We examined the mechanism of negative added mass, which results from the localized hydrodynamic resonance.

• Proceedings of the IEEK Conference
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• 2006.06a
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• pp.817-818
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• 2006

In Magnetic Resonance Imaging(MRI), the QRS complex of ECG is used as a trigger signal for MRI scan. But, gradient and RF(radio frequency) artifacts which are caused to static and dynamic field in MRI scanner cause interference in the ECG. Also, the signal shape of theses artifacts can be similar to the QRS-complex, causing possible misinterpretation during patient monitoring and false gating of the MRI. In case of using general FIR or IIR band-pass filters for minimizing the artifacts, artifact-reduction-ratio is not excellent. So, an adaptive real-time digital filter is proposed for reduction of noise by gradient and RF(radio frequency) artifacts. The proposed filter for MRI-Gating is based on the noise-canceller with NLMS(Normalized Least Mean Square) algorithm. The reference signals of the adaptive noise canceller are a combination of the noisy three channel ECG signals. In conclusions, the proposed method showed the acceptable quality of ECG signal with sufficient SNR for gating the MRI and possibility of real time implementation.

• JSTS:Journal of Semiconductor Technology and Science
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• v.11 no.4
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• pp.295-301
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• 2011

A triple-band transceiver module for 2.3/2.5/3.5 GHz mobile WiMAX, IEEE 802.16e, applications is introduced. The suggested transceiver module consists of RFIC, reconfigurable/multi-resonance MIMO antenna, embedded PCB, mobile WiMAX base band, memory and channel selection front-end module. The RFIC is fabricated in $0.13{\mu}m$ RF CMOS process and has 3.5 dB noise figure(NF) of receiver and 1 dBm maximum power of transmitter with 68-pin QFN package, $8{\times}8\;mm^2$ area. The area reduction of transceiver module is achieved by using embedded PCB which decreases area by 9% of the area of transceiver module with normal PCB. The developed triple-band mobile WiMAX transceiver module is tested by performing radio conformance test(RCT) and measuring carrier to interference plus noise ratio (CINR) and received signal strength indication (RSSI) in each 2.3/2.5/3.5 GHz frequency.

• Journal of Physiology & Pathology in Korean Medicine
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• v.19 no.2
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• pp.323-328
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• 2005

Oriental medicine specifies points which have proven to be valuable in the treatment of certain diseases or conditions of pain-the so-called master points and alarm points of the acupuncture system. The idea of applying colorpuncture via the master points already suggested itself on the basis of the very old correlations between organs and organ systems and colors which we find in a number of different therapeutic systems and trations. Each of the twelve organs of the acupuncture system has an alarm point which is usually not situated on the related meridian but on another channel. These alarm points are always to be found in the vicinity of the organs they are associated with. The combined use of master points and alarm points is a simple and excellent way of using colorpuncture. Via their inherent vibrational frequencies, the healings rays of colored light radiation are capable of releasing potent resonance forces within the organism, thus contributing to the alleviation and healing of acute and chronic diseases.

• Journal of Biomedical Engineering Research
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• v.15 no.2
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• pp.175-182
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• 1994

The international standard for digital compression and coding of continuous-tone still image known as JPEG (Joint Photographic Experts Group) standard is investigated for medical image archiving and communication. The JPEG standard has widely been accepted in the areas of electronic image communication, computer graphics, and multimedia applications, however, due to the lossy character of the JPEG compression its application to the field of medical imaging has been limited. In this paper, the JPEG standard is investigated for medical image compression with a series of head sections of magnetic resonance (MR) images (256 and 4096 graylevels, $256 {\times}256$size). Two types of Huffman codes are employed, i. e., one is optimized to the image statistics to be encoded and the other is a predetermined code, and their coding efficiencies are examined. From experiments, compression ratios of higher than 15 were obtained for the MR images without noticeable distortion. Error signal in the reconstructed images by the JPEG standard appears close to random noise. Compared to existing full-frame bit-allocation technique used for radiological image compression, the JPEG standard achieves higher compression with less Gibb's artifact. Feature of the progressive image build-up of the JPEG progressive coding may be useful in remote diognosis when data is transmitted through slow public communication channel.

• Current Optics and Photonics
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• v.3 no.3
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• pp.199-203
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• 2019

The characteristics of a photonic crystal fiber sensor with reuleaux triangle are studied by using the finite element method. The wavelength sensitivity of the designed optical fiber sensor is related to the arc radius of the reuleaux triangle. Whether the core area is solid or liquid as well as the refractive index of the liquid core contributes to wavelength sensitivity. The simulation results show that larger arc radius leads to higher sensitivity. The sensitivity can be improved by introducing a liquid core, and higher wavelength sensitivity can be achieved with a lower refractive index liquid core. In addition, the specific channel plated with gold film is polished and then analyte is deposited on the film surface, in which case the position of the resonance peak is the same as that of the complete photonic crystal fiber with three analyte channels being filled with analyte. This means that filling process becomes convenient with equivalent performance of designed sensor. The maximum wavelength sensitivity of the sensor is 10200 nm/RIU and the resolution is $9.8{\times}10^{-6}RIU$.

• Journal of Genetic Medicine
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• v.18 no.2
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• pp.137-141
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• 2021

Genetic causes of developmental and epileptic encephalopathy (DEE) have been rapidly uncovered from mid-2010s. The mutations of gene enconding calcium channel, voltage-dependent, P/Q type, alpha 1A subunit (CACNA1A) are recently detected in DEE, which gene is already known well in familial hemiplegic migrine type 1 or episodic ataxia type 2. Ketogenic diet therapy (KDT) is effective in some DEE, which data is short in CACNA1A encephalopathy. A 3-month-old male with global developmental delay and multidrug-resistant focal seizures was diagnosed as epilepsy of infancy with migrating focal seizures (EIMFS). Brain magnetic resonance imaging and metabolic screening were all normal. Whole exome sequencing revealed two variants of CACNA1A: c.899A>C, and c.2808del that is from his mother. His seizures disappeared within 3 days whenever on KDT, which recurred without it. To our knowledge, this rare case of EIMFS with novel mutations of CACNA1A, is the first report in CACNA1A encephalopathy becoming seizure-free on KDT.

• Journal of Sensor Science and Technology
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• v.32 no.1
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• pp.39-43
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• 2023

Microscale thermophysical property measurements of liquids have been developed considering the increasing interest in the thermal management of cooling systems and energy storage/transportation systems. To accurately predict the heat transfer performance, information on the thermal conductivity, heat capacity, and density is required. However, a simultaneous analysis of the thermophysical properties of small-volume liquids has rarely been considered. Recently, we proposed a new methodology to simultaneously analyze the aforementioned three intrinsic properties using heater-integrated fluidic resonators (HFRs) in an atmospheric pressure environment comprising a microchannel, resistive heater/thermometer, and mechanical resonator. Typically, the thermal conductivity and volumetric heat capacity are measured based on a temperature response resulting from heating using a resistive thermometer, and the specific heat capacity can be obtained from the volumetric heat capacity by using a resonance densitometer. In this study, we analyze methods to improve the thermophysical property measurement performance using HFRs, focusing on the effect of the ambience around the sensor. The analytical method is validated using a numerical analysis, whose results agree well with preliminary experimental results. In a vacuum environment, the thermal conductivity measurement performance is enhanced, except for the thermal conductivity range of most gases, and the sensitivity of the specific heat capacity measurement is enhanced owing to an increase in the time constant.

• Progress in Superconductivity and Cryogenics
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• v.8 no.1
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• pp.59-64
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• 2006

A closed-loop cryogenic cooling system for high field magnets is presented. This design is motivated by our recent development of cooling system for 21 tesla Fourier Transform ion Cyclotron Resonance (FT-ICR) superconducting magnets without any replenishment of cryogen. The low temperature superconducting magnets are immersed in a subcooled 1.8 K bath, which is connected hydraulically to the 4.2 K reservoir through a narrow channel. Saturated liquid helium is cooled by Joule-Thomson heat exchanger and flows through the JT valve, isenthalpically dropping its pressure to approximately 1 6 kPa, corresponding saturation temperature of 1.8 K. Helium gas exhausted from pump is now recondensed by two-stage cryocooler located after vapor purify system. The amount of cryogenic Heat loads and required mass flow rate through closed-loop are estimated by a relevant heat transfer analysis, from which dimensions of JT heat exchanger and He II heat exchanger are determined. The detailed design of cryocooler heat exchanger for helium recondensing is performed. The effect of cryogenic loads, especially superfluid heat leak through the gap of weight load relief valve, on the dimensions of cryogenic system is also investigated.

• The Korean Journal of Physiology and Pharmacology
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• v.24 no.6
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• pp.503-516
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• 2020

KCNQ family constitutes slowly-activating potassium channels among voltage-gated potassium channel superfamily. Recent studies suggested that KCNQ4 and 5 channels are abundantly expressed in smooth muscle cells, especially in lower urinary tract including corpus cavernosum and that both channels can exert membrane stabilizing effect in the tissues. In this article, we examined the electrophysiological characteristics of overexpressed KCNQ4, 5 channels in HEK293 cells with recently developed KCNQ-specific agonist. With submicromolar EC₅₀, the drug not only increased the open probability of KCNQ4 channel but also increased slope conductance of the channel. The overall effect of the drug in whole-cell configuration was to increase maximal whole-cell conductance, to prolongate the activation process, and left-shift of the activation curve. The agonistic action of the drug, however, was highly attenuated by the co-expression of one of the β ancillary subunits of KCNQ family, KCNE4. Strong in vitro interactions between KCNQ4, 5 and KCNE4 were found through Foster Resonance Energy Transfer and co-immunoprecipitation. Although the expression levels of both KCNQ4 and KCNE4 are high in mesenteric arterial smooth muscle cells, we found that 1 μM of the agonist was sufficient to almost completely relax phenylephrine-induced contraction of the muscle strip. Significant expression of KCNQ4 and KCNE4 in corpus cavernosum together with high tonic contractility of the tissue grants highly promising relaxational effect of the KCNQ-specific agonist in the tissue.