• Title/Summary/Keyword: channel gradient

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Role of $Na^+/Ca^{2+}$ Exchange in the Control of Contractility in Rabbit Basilar Arterial Smooth Muscle

  • Kim, Eui-Yong;Han, Jin
    • The Korean Journal of Physiology
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    • v.28 no.2
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    • pp.159-167
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    • 1994
  • The contraction of rabbit basilar artery was examined as a function of changes in the $Na^+$ electrochemical gradient in order to determine the contribution of $Na^+/Ca^{2+}$ exchange to the modulation of contractility. Ouabain $(10^{-5}\;M)$ or $K^+-free$ Tyrode solution caused an increase in tonic tension even in the presence of a $Ca^{2+}$ channel blocker $(10^{-6}\;M\;verapamil)$ and an ${\alpha}-receptor$ blocker $(10^{-5}\;M\;phentolamine)$. After treatment with ouabain $(10^{-5}\;M)$, contractions were augmented by reduction of external $Na^+$ concentration. The longer the treatment with ouabain $(10^{-5}\;M)$ was, the larger the amplitude of $Na^+-free$ contracture was. $Na^+-free$ contracture wag induced by either substitution of equimolar Tris for $Na^+$ or substitution of equimolar $Li^+\;for\;Na^+$. The competition between $Na^+\;and\;Ca^{2+}$ for the $Na^+/Ca^{2+}$ exchange carrier would exist, because it was observed that contractility was dependent on the $Na^+$ electrochemical gradient or the extracellular $Ca^{2+}$ concentration (2 mM, 4 mM). Ryanodine $(10^{-7}\;M)$, the blocker of intracellular $Ca^{2+}$ release from the sarcoplasmic reticulum, did not suppress the development of $Na^+-free$ contracture. The contractile response to norepinephrine $(10^{-6}\;M)$ was augmented by reducing the extracellular $Na^+$ concentration. The relaxation rate from caffeine-induced contraction was dependent on the extracellular $Na^+$ concentration (0 mM, 140 mM). From the above results, it could be suggested that $Na^+/Ca^{2+}$ exchange can move $Ca^{2+}$ either into or out of rabbit basilar arterial smooth muscle. $Ca^{2+}$ entry or extrusion is dependent upon the $Na^+$ electrochemical gradient. $Na^+/Ca^{2+}$ exchange plays a significant role in the regulation of contractility in rabbit basilar arterial smooth muscle.

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A study on waterfall classification by form and processes (폭포의 지형학적 분류에 관한 연구)

  • PARK, Kyeong;KIM, Ji Young
    • Journal of The Geomorphological Association of Korea
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    • v.21 no.4
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    • pp.85-96
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    • 2014
  • A waterfall is a channel unit with steep bedrock. No strict criteria for height, water volume, gradient to define waterfalls exist in Korea. The goal of our study is to classify waterfalls based on morphological forms which are the outcomes of developmental processes. The genesis of waterfall depends upon erosional properties of waterfall. The height, gradient, bedrock strength and stream power of waterfalls are regarded as the main factors, by which waterfalls can be classified. We find out that the most important factor for the development of waterfalls is joint system. Development of joint system varies depending on bedrocks. Flow directions and erosional types are decided by the density and direction of joint system in the bedrock, which also decide the height and gradient of stream bed. Joint type decides the gradients of the bed, gradient and height of waterfalls, therefore, decides morphological forms.

Thermophoretic Control of Particle Transport in a Microfluidic Channel (미세유체 채널 내에서 열영동에 의한 입자이동 제어)

  • So, Ju-Hee;Koo, Hyung-Jun
    • Korean Chemical Engineering Research
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    • v.57 no.5
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    • pp.730-734
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    • 2019
  • Thermophoresis is a transport phenomenon of particles driven by a temperature gradient of a medium. In this paper, we discuss the thermophoresis of particles in microfluidic channels. In a non-fluidic, stagnant channel, the thermophoretic transport of micro-particles was found to be larger in proportion to the voltage applied to the platinum wire heat source installed in the channel. The variation of the temperature around the platinum wire depending on the voltage was estimated, by using the Callendar-van Dusen equation. The thermophoretic behavior of nano-particles in the same system was observed, which is similar to that of the microparticles. Finally, we fabricated a Y-shaped microfluidic channel with a platinum wire heat source installed in the channel, to realize the thermophoretic phenomenon of the particles in the suspension flowing through the channel. It is shown that the flow of the suspension can be controlled based on the thermophoretic principle.

An Application of Physico-Environmental Evaluation System of Stream - Focusing on urban streams - (하천의 물리 환경성 평가체계의 적용 - 도시하천을 중심으로 -)

  • Jung, Hea-Reyn;Kim, Ki-Heung
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.20 no.1
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    • pp.55-75
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    • 2017
  • The purpose of this study is to present the basic data for restoration of physical stream environment by analyzing habitat variables because habitat environment is changed due to the construction of waterfront space in urban streams. Assessment results of 10 habitat variables(three divisions) were almost same as optimal condition, in the reach of reference stream where there are no stream crossing structures and channel alteration. Assessment results of reaches in urban rivers, where streams were improved on water-friendly recreation activities, appeared to be marginal condition. Because habitat environment got worse due to stream improvement works such as construction of weir for water landscape, stepping stones for walking, low water revetment and high water revetment, and high water channel. In addition, in the case of mid gradient stream, the frequency of riffles was small or not existed because the intervals of the river crossing structures was short. In the case of mild stream types, the diversity of the pool was damaged due to the deposition of sludge in the upstream pool of weir and the installation of low water revetment.

Three Dimensional FEM Simulation for Spinning of Non-circular Fibers

  • Kim, Heejae;Chung, Kwansoo;Youn, Jae-Ryoun
    • Fibers and Polymers
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    • v.1 no.1
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    • pp.37-44
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    • 2000
  • A finite element method is employed fer a flow analysis of the melt spinning process of a non-circular fiber, a PET(polyethylene terephthalate) filament. The flow field is divided into two regions of die channel and spin-line. A two dimensional analysis is used for the flow within the die channel and a three dimensional analysis fur the flow along the spin-line. The Newtonian fluid is assumed for the PET melt and material properties are considered to be constant except for the viscosity. Effects of gravitation, air drag force, and surface tension are neglected. Although the spin-line length is 4.5 m only five millimeters from the spinneret are evaluated as the domain of the analysis. Isothermal and non-isothermal cases are studied fer the flow within the die channel. The relationship between the mass flow rate and the pressure gradient is presented for the two cases. Three dimensional flow along the spin-line is obtained by assuming isothermal conditions. It is shown that changes in velocity and cross-sectional shape occur mostly in the region of 1mm from the die exit.

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Turbulent Flow over Thin Rectangular Riblets

  • El-Samni O. A.;Yoon Hyun Sik;Chun Ho Hwan
    • Journal of Mechanical Science and Technology
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    • v.19 no.9
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    • pp.1801-1810
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    • 2005
  • The effect of longitudinal thin rectangular riblets aligned with the flow direction on turbulent channel flow has been investigated using direct numerical simulation. The thin riblets have been modeled using the immersed boundary method (IBM) where the velocities at only one set of vertical nodes at the riblets positions are enforced to be zeros. Different spacings, ranging between 11 and 43 wall units, have been simulated aiming at getting the optimum spacing corresponding to the maximum drag reduction while keeping the height/spacing ratio at 0.5. Reynolds number based on the friction velocity ${\mu}_\tau$ and the channel half depth $\delta$ is set to 150. The flow is driven by adjusted pressure gradient so that the mass flow rate is kept constant in all the simulations. This study shows similar trend of the drag ratio to that of the experiments at the different spacings. Also, this research provides an optimum spacing of around 17 wall units leading to maximum drag reduction as experimental data. Explanation of drag increasing/decreasing mechanism is highlighted.

An instability criterion for viscoelastic flow past a confined cylinder

  • Dou, Hua-Shu;Phan-Thien, Nhan
    • Korea-Australia Rheology Journal
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    • v.20 no.1
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    • pp.15-26
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    • 2008
  • It has been known that there is a viscoelastic instability in the channel flow past a cylinder at high Deborah (De) number. Some of our numerical simulations and a boundary layer analysis indicated that this instability is related to the shear flow in the gap between the cylinder and the channel walls in our previous work. The critical condition for instability initiation may be related to an inflection velocity profile generated by the normal stress near the cylinder surface. At high De, the elastic normal stress coupling with the streamline curvature is responsible for the shear instability, which has been recognized by the community. In this study, an instability criterion for the flow problem is proposed based on the analysis on the pressure gradient and some supporting numerical simulations. The critical De number for various model fluids is given. It increases with the geometrical aspect ratio h/R (half channel width/cylinder radius) and depends on a viscosity ratio ${\beta}$(polymer viscosity/total viscosity) of the model. A shear thinning first normal stress coefficient will delay the instability. An excellent agreement between the predicted critical Deborah number and reported experiments is obtained.

A Comprehensive and Practical Image Enhancement Method

  • Wu, Fanglong;Liu, Cuiyin
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.13 no.10
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    • pp.5112-5129
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    • 2019
  • Image enhancement is a challenging problem in the field of image processing, especially low-light color images enhancement. This paper proposed a robust and comprehensive enhancement method based several points. First, the idea of bright channel is introduced to estimate the illumination map which is used to attain the enhancing result with Retinex model, and the color constancy is keep as well. Second, in order eliminate the illumination offsets wrongly estimated, morphological closing operation is used to modify the initial estimating illumination. Furthermore, in order to avoid fabricating edges, enlarged noises and over-smoothed visual features appearing in enhancing result, a multi-scale closing operation is used. At last, in order to avoiding the haloes and artifacts presented in enhancing result caused by gradient information lost in previous step, guided filtering is introduced to deal with previous result with guided image is initial bright channel. The proposed method can get good illumination map, and attain very effective enhancing results, including dark area is enhanced with more visual features, color natural and constancy, avoiding artifacts and over-enhanced, and eliminating Incorrect light offsets.

Interfacial Friction Factors for Air-Water Co-current Stratified Flow in Inclined Channels

  • Choi, Ki-Yong;No, Hee-Cheon
    • Proceedings of the Korean Nuclear Society Conference
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    • 1997.10a
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    • pp.481-486
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    • 1997
  • The interfacial shear stress is experimentally investigated for co-current air-water stratified flow in inclined rectangular channels having a length of 1854mm, width of 120mm and height of 40mm at almost atmospheric pressure. Experiments are carried out in several inclinations from $0^{\circ}\;up\;to\;10^{\circ}$. The local film thickness and the wave height are measured at three locations, i.e., L/H = 8,23, and 40. According to the inclination angle, the experimental data are categorized into two groups; nearly horizontal data group ($0^{\circ}\;{\leq}\;{\theta}\;{\leq}\;0.7^{\circ}$), and inclined channel data group ($0.7^{\circ}\;{\leq}\;{\theta}\;{\leq}\;10^{\circ}$). Experimental observations for nearly horizontal data group show that the flow is not fully developed due to the water level gradient and the hydraulic jump within the channel. For the inclined channel data group, a dimensionless wave height, $\Delta$h/h, is empirically correlated in terms of $Re_{G}$ and h/H. A modified root-mean-square wave height is proposed to consider the effects of the interfacial and wave propagation velocities. It is found that an equivalent roughness has a linear relationship with the modified root-mean-square wave height and its relationship is independent of the inclination.

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Prediction of Bypass Flow Rate through Gas Diffusion Layer in PEMFC with Serpentine Flow Channels (사행 유로를 갖는 고분자 전해질 연료전지의 기체확산층 내부에서의 우회 유동 예측)

  • Jeon, Se-Gye;Kim, Kuoung-Youn
    • Transactions of the Korean hydrogen and new energy society
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    • v.23 no.4
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    • pp.293-299
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    • 2012
  • The serpentine flow channel is widely used in polymer electrolyte membrane fuel cells (PEMFCs) to prevent flooding phenomena because it effectively removes liquid water in the flow channel. The pressure drop between inlet and outlet increases as compared with straight channels due to minor losses associated with the corners of the turning configurations. This results in a strong pressure gradient between adjacent channels in specific regions, where some amount of reactant gas can be delivered to catalyst layers by convection through a gas diffusion layer (GDL). The enhancement of the convective flow in the GDL, so-called bypass flow, affects fuel cell performance since the bypass flow influences the reactant transport and thus its concentration over the active area. In the present paper, for the bipolar plate design, a simple analytic model has been proposed to predict the bypass flow in the serpentine type flow channels and validated with three-dimensional numerical simulation results.