• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.19 no.1
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• pp.73-82
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• 2024

Objectives This study aims to evaluate the effectiveness of cervical chuna manipulative treatment (CCMT) in patients with peripheral facial paralysis (PFP). Methods We conducted a comprehensive search of MEDLINE, CENTRAL, EMBASE, KMbase, OASIS and ScienceOn, and CNKI for randomized controlled trials (RCTs) comparing CCMT for PFP up to April 25, 2024. Risk of Bias was assessed using the Cochrane RoB tool. Results Among the 462 studies retrieved, 5 RCTs with a total of 340 patients were included in the systematic review. Of these, 4 RCTs that reported the total effectiveness rate as the primary outcome were included in the meta-analysis. CCMT combined with acupuncture showed significant improvement in total effectiveness rate compared to acupuncture alone (Relative Ratio [RR] 1.14, 95% CI 1.04 to 1.26, I²=49, P<0.008). However, the included studies had some limitations including uncertain risk of bias and short follow-up periods. Conclusions CCMT may be an effective treatment for PFP. Due to the low quality of evidence from the included studies, high-quality, well-designed RCTs are needed to further verify the effectiveness and safety of CCMT.