• Journal of Microbiology and Biotechnology
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• 제15권2호
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• pp.425-427
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• 2005

The steam distillate obtained from Thujopsis dolabrata var. hondai sawdust was fractionated by centrifugal thin-film evaporation, and the fractions were then investigated for antiplatelet activity using washed rabbit platelets. The biologically active constituent of T. dolabrata var. hondai sawdust was isolated by silica gel column and HPLC chromatographies and characterized as carvacrol by various spectral analyses. Carvacrol inhibited platelet aggregation induced by collagen, arachidonic acid, and platelet activating factor with IC$_{50}$ values of 12.6, 2.5, and 385.3 $\mu$M, respectively. However, carvacrol had no effect on thrombin, calcium ionophore A23l87, or phorbol l2-myristate l3-acetate induced platelet aggregation. Carvacrol was a much more potent inhibitor, as antiplatelet agents, compared with aspirin. These results suggest that carvacrol isolated from T. dolabrata var. hondai sawdust may be useful as a lead compound for inhibiting arachidonic acid-induced platelet aggregation.

• 대한설비공학회:학술대회논문집
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• 대한설비공학회 2008년도 하계학술발표대회 논문집
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• pp.1309-1314
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• 2008

I.G.G is abbreviation for Inert Gas Generator, High temperature in Cargo Tank it desulfurize, exhausted and froze the gas that combined brimstone element and soot, then supply Inert gas by blower, and mack tank inside incombustible range this is equipment that nip in the bud the explosion. The blower for suppling inactivated gas has big impeller with heavy weight to achieve the high pressure, it causes a delay for first operation time and too much load is delivered to motor, total destruction by fire of motor is happening frequently. On this research, we will reduce the size & weight of impeller and install it with several stage, it makes an effect for reducing the first operation time. We also intend to contribute to efficient IGG blower design by research a flowing & pressure specialty from the diameter of impeller, number of blade, and size of casing.

• 한국유체기계학회 논문집
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• 제17권1호
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• pp.41-46
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• 2014

The thermal-flow characteristics of screw compressor were numerically investigated with various geometrical configurations of its coolant flow passage applied to the separate block for enhancing the heat transfer performance of it. The length ratio($L_s/D$=4.8, 5.6, 6.4) and thickness ratio(t/D=0.2, 0.4, 0.6) of the separate block in the flow passage of the water jacket were adopted to design parameters. Results showed that the pressure drop and heat transfer were increased as the length of separate block increases due to the flow separation and centrifugal force. The results were graphically depicted with various flow and geometrical conditions.

• 한국철도학회논문집
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• 제15권2호
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• pp.162-171
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• 2012

본 연구에서는 곡선부를 주행하는 틸팅열차와 궤도와의 동적상호작용을 고려한 동적해석을 수행하기 위한 해석기법을 제시하였다. 본 연구에서는 3차원 차량요소를 이용하여 틸팅열차를 모형화하였으며, 틸팅열차의 곡선부 주행시 차량의 주행방향이 크게 변화하는 상황에서 주행속도 및 원곡선 반경에 상응하는 원심력의 표현, 선로의 캔트량, 차륜-레일의 접촉각 및 열차의 틸팅각 등을 고려한 동적상호작용해석 방법을 제안하였다. 제안된 해석방법은 기본적인 검증예제들에서 만족할만한 결과를 보여주었으며, 실제적인 문제에 적용이 가능할 것으로 기대된다.

• 한국결정성장학회지
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• 제3권1호
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• pp.18-30
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• 1993

균일한 자장과 비균일한 자장이 도가니에 가하여졌을 때의 Czochralski유동장이 수치적으로 해석되었다. 여기에서 부력의 효과, thermocapillarity 효과, 원심력의 효과, 자장의 효과등이 Czochralski유동장을 지배하고 있다. 자오면에서의 속도성분과 회전방향의 속도성분이 구하여졌으며 온도, 전류의 흐름 등이 해석되었다. 균일한 자장의 경우에 세기가 증가하면 모든 속도성분이 작아지고 있으며 결정표면 아래에서 회전방향으로의 전류의 세기가 증가한다. 불균일한 자장의 경우에는 자장의 불균일성이 증가하면 자오면에서의 평면유동은 억제되는 반면 회전방향의 속도성분은 더 증가하게 된다. 이와 같은 여러 형태의 자장의 영향아래에서의 Czochralski 유동장에 대한 이해는 도가니(Crucible)안의 용질 및 불순물의 농도에 관한 거동을 연구할 수 있는 기초를 제공하고 있다.

• 설비공학논문집
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• 제3권4호
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• pp.241-249
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• 1991

A quasi-three dimensional calculation method is presented on the basis of Wu's idea using finite element methods. In B-B flow the governing equations are cast into a single equation to overcome the restriction of the type of turbomachinery, and Kutta condition is exactly assured by introducing a combination of two kinds of stream functions. In H-S flow a dissipative force which is assumed to be opposed to the relative velocity is added to the governing equation for a consistent loss model. The entropy change along each streamline is then calculated by assuming that the dissipative force may be a force coming from laminar viscous stresses with inviscid velocity distributions. Both the flow solvers are combined to build a three-dimensional flow field through a few iterations. For an effect of the distortion of H-S flow surface the body forces are computed after each B-B flow calculation is finished. Mizuki's centrifugal impellers are tested numerically. The reliability of the numerical solution compared with experimental data is guaranteed.

• 한국주조공학회지
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• 제17권5호
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• pp.443-449
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• 1997

The purpose of this study is to investigate the effect of P addition and homogenizing heat treatment on the mechanical properties of Cu-Sn-Ni alloy. The addition of P was 0.025wt.%P to 0.085wt.%P and homogenizing heat-treated at 400, 500, $600^{\circ}C$ under $N_2$ gas atmosphere. Mechanical properties was investigated in this study were Rockwell hardness, tensile strength, and elongation. Tensile strength and elongation increased with P and homogenizing time. Temperature was significantly influence on mechanical properties. Hardness decreased with increasing homogenizing time and temperature, but 0.085wt.%P specimen was showed higher hardness and lower tensile strength and elongation than 0.073wt.%P specimen due to the presence of more $Cu_3P$ in matrix.

• Nuclear Engineering and Technology
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• 제53권12호
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• pp.3892-3901
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• 2021

The pressure drop of a moisture separator in a steam generator is the important design parameter to ensure the successful performance of a nuclear power plant. The moisture separators have a wide range of operating conditions based on the arrangement of them. The prediction of the pressure drop in a moisture separator is challenging due to the complexity of the multi-dimensional two-phase vortex flow. In this study, the moisture separator test facility using the air/water two-phase flow was used to predict the pressure drop of a moisture separator in a Korean OPR-1000 reactor. The prototypical steam/water two-phase flow conditions in a steam generator were simulated as air/water two-phase flow conditions by preserving the centrifugal force and vapor quality. A series of experiments were carried out to investigate the effect of hydraulic characteristics such as the quality and liquid mass flux on the two-phase pressure drop. A new prediction model based on the scaling law was suggested and validated experimentally using the full and half scale of separators. The suggested prediction model showed good agreement with the steam/water experimental results, and it can be extended to predict the steam/water two-phase pressure drop for moisture separators.

• BMB Reports
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• 제37권3호
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• pp.376-382
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• 2004

The Epstein-Barr-transformed B lymphoblastoid cell lines, LCL, which express antigens, are potential antigen-presenting cells (APCs) for the induction of cytotoxic T lymphocytes in vitro. However, transfecting LCL with subsequent selection by antibiotics is notoriously difficult because the plating efficiencies of LCL are reported to be 1% or less. Therefore, this study investigated the optimal conditions for increasing the transduction efficiency of a recombinant adenovirus to LCL for use as a source of APCs. The transduction efficiencies were < 13% (SD $\pm$ 2.13) at a multiplicity of infection (MOI) of 100, while it was increased to 28% (SD $\pm$ 9.43) at an MOI of 1000. Moreover, its efficiencies to LCL that expressed the coxsackie adenovirus receptor were increased to 60% (SD $\pm$ 6.35) at an MOI of 1000, and were further increased to 70% (SD $\pm$ 4.56) when combined with the centrifugal method. The cationic liposome or anionic polymer had no effect on the transduction efficiency when compared to that of the centrifugal method. These results may be used as a convenient source of target cells for a CTL assay and/or autologous APCs for the induction of the in vitro CTL responses that are specific to viral and tumor antigens.

• 한국지반공학회논문집
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• 제30권6호
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• pp.5-21
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• 2014

지진시 불포화 도로성토의 붕괴는 지하수 및 강우의 침투에 기인한 함수비의 증가가 그 원인이 됨이 지적되어 왔다. 따라서, 이와 같은 지반재해의 방지를 위한 합리적 보강방안 및 적절한 설계기준의 정립을 위해 불포화 도로성토의 동적안정성 및 변형모드에 대한 함수비의 영향을 연구할 필요가 있다. 본 연구에서는 불포화 도로성토의 변형 및 파괴거동에 대한 함수비의 영향을 연구하기 위해 상이한 함수비를 갖는 도로성토 모형에 대하여 동적 원심모형실험을 진행하였다. 본 실험에서는 도로성토 모형에 대한 동적하중 부가시의 변위, 간극수압 및 가속도의 계측을 통해 최적함수비 부근 및 최적함수비보다 높은 함수비를 갖는 불포화 도로성토에 대한 동적 거동을 고찰하였다. 이와 함께, 화상해석에 의한 변위 및 변형율 분포의 분석을 통하여 최적함수비보다 높은 함수비를 갖는 불포화 도로성토의 변형모드를 구명하였다. 이로부터 사면 천단부의 침하는 천단부 아래에서의 체적압축에 기인하며, 구속압력이 작은 사면 선단부 및 사면 표면부 부근에서는 체적팽창을 동반한 큰 전단변형이 발생함을 확인하였다.