• The Korean Journal of Pain
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• v.8 no.2
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• pp.336-340
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• 1995

Impairment of erectile function, although normally a benign disorder, has a profound impact on the well-being of many men. Penile erection is produced by a complex series of events involving cognition, peripheral sensory input, central and peripheral autonomic nervous events and hormonal vascular events. The multiplicity of potential determinants identified suggest that impotence does not inexorably accompany age, but it is an arugmented significantly modifiable paraaging phenomena. A 53 year old male patients developed sudden impotence. The patients did not respond to intracavernous injection of papaverine. This patient was successfuly treated with 4 repeated stellate ganglion blocks.

• Journal of Integrative Natural Science
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• v.7 no.4
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• pp.227-233
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• 2014

Caspases, a family of cysteinyl aspartate-specific proteases plays a central role in the regulation and the execution of apoptotic cell death. Activation of caspases-3 stimulates a signaling pathway that ultimately leads to the death of the cell. Hence, caspase-3 has been proven to be an effective target for reducing the amount of cellular and tissue damage. In this work, comparative molecular similarity indices analysis (CoMSIA) was performed on a series of 3,4-dihydropyrimidoindolones derivatives which are inhibitors of caspase-3. The best predictions were obtained for CoMSIA model ($q^2$ = 0.586, $r^2$ = 0.955). The predictive ability of test set ($r^2_{pred}$) was 0.723. Statistical parameters from the generated QSAR models indicated the data is well fitted and have high predictive ability. Our theoretical results could be useful to design novel and more potent caspase-3 derivatives.

• Proceedings of the Korean Institute of IIIuminating and Electrical Installation Engineers Conference
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• 1995.10a
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• pp.47-52
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• 1995

This paper presents a new approach in the design of an electronic ballast for fluorescent lamps in the range of 10∼20W. The central point of the design lies in the equivalent concepts for a lamp and for the inverter part of an electronic ballast. The ballast, which adopts half-bridge inverter topology, is designed to adjust ifself to a predefined range of lamp power output by frequency control using MCU. At first, the circuit parameters were estimated using PSpice simulatio, and then were made varied according to the selection of an optimal frequency for each lamp. A series of experiments using fluorescent lamps of 11W, 15W, and 20W were carried out to verify the proposed design. As a result of the experiments, all the three lamps of different kind were run normally with the same ballast under consideration, And the characteristics on lamp starting and light output were satisfactory compared to existen single-output electronic ballasts.

• Toxicological Research
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• v.21 no.3
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• pp.195-208
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• 2005

Diabetes is a major cause of morbidity and mortality, and associated with a high risk of atherosclerosis, and liver, kidney, nerve and tissue damage. Defective insulin secretion in pancreas and/or insulin resistance in peripheral tissues is a central component of diabetes. It is well established that, regardless of the degree of muscle insulin resistance, glucose levels in diabetic and non-diabetic individuals are determined by the rate of hepatic glucose production. Moreover recently studies using liver-specific insulin receptor knockout mice show the paramount role of the liver in insulin resistance and diabetes. Insulin exerts a multifaceted and highly integrated series of actions via its intracellular signaling systems. The first major section of this review defines the major insulin-mediated signaling pathways including phosphatidylinositol 3-kinase and mitogen activated protein kinases. The second major section of the review presents a summary and evaluation of methods for determination of the role and function of signaling pathways, including methods for determination of kinase phosphorylation, the use of pharmacological inhibitors of kinase and dominant-negative kinase constructs, and the application of new RNA interference methods.

• Journal of Marine Bioscience and Biotechnology
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• v.3 no.1
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• pp.38-41
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• 2008

Fish is a major source of protein for the Senegalese population. Fishing plays a dominant role in the Government's policy towards generating employment. It currently generates about 100,000 direct jobs (fishermen) for nationals, of which more than 90% are in small-scale fishing. The fishing industry also contributes to Government revenue through different agreements. In addition to associated dues, fishing agreements imply a series of economic, trade and technical counterparts. Under the latest fishing agreement concluded by Senegal and the European Union (1997-2001), direct financial compensation amounts to about CFAF 32 billion. Despite its economic and social importance, the sector has to face serious disequilibria both in resource exploitation and market supply: the coastal demersal (deep lying fish) stocks with high market value (mostly exported) are fully and even over-exploited, with a serious risk of local market supply shortages looming ahead as the fishing effort shifts from locally consumed species to export-oriented ones.

• ALGAE
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• v.24 no.2
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• pp.67-77
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• 2009

The marine phytoplankton diatom Thalassiosira species are described from the Korean coastal waters, based onobservations of Fine structutre of its frustules. As a fourth series, this study deals with 5 Thlassiosira species (T. decip-iens, T. ecgentrica, T. mala, T. nodulolinmta, and T. proschinae). The most striking features of these species are also theform and position of two processes on frustules. There is a central strutted process on valve face except T. nodvlolin-eata, which has a modified one on its center. The extemal tubes of marginal strutted processes are divided twoforms: "pile" form in T. decipiens and T. proschkinae, "short straw" form in T. eccentrica and T. nodulolineata. T. maladoes not present the extemal tubes in valve margin. The labiate processes are located in valve margin except T.proschkinae, which has it on valve face. Of theae, thrce species (T. mala, T. nodulineata at a final contentration of 5%and T. proschkinae were newly recorded in the coastal waters of Korea.

• Communications of the Korean Mathematical Society
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• v.30 no.4
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• pp.439-446
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• 2015

The main objective of this paper is to establish certain explicit expressions for the Humbert functions ${\Phi}_2$(a, a + i ; c ; x, -x) and ${\Psi}_2$(a ; c, c + i ; x, -x) for i = 0, ${\pm}1$, ${\pm}2$, ..., ${\pm}5$. Several new and known summation formulas for ${\Phi}_2$ and ${\Psi}_2$ are considered as special cases of our main identities.

• Journal of the Korean Applied Science and Technology
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• v.25 no.2
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• pp.240-251
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• 2008

The central role of tyrosine phosphorylation in cell proliferative signaling mechanisms provides another target for chemotherapy. The aim of this research is to develop new quinazoline derivatives that possess the inhibitory activity for depidermal growth factor receptor (EGFR) tyrosine kinase (TK) as protein kinase inhibitors. In this work, a series of new 4-anilino-6-guanidino-7-methoxyquinazoline derivatives (12a-l) were synthesized by the introduction of guanidine moiety at C-6 of quinazoline nucleus and evaluated for their EGFR TK inhibitory activities.

• Steel and Composite Structures
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• v.24 no.6
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• pp.659-670
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• 2017

In the present work, an analytical solution for the static analysis of laminated composites, functionally graded and sandwich singly and doubly curved panels on the rectangular plan-form, subjected to uniformly distributed transverse loading is presented. Mathematical formulation is based on the higher order shear deformation theory and principle of virtual work is applied to derive the equations of equilibrium subjected to small deformation. A solution methodology based on the fast converging finite double Chebyshev series is used to solve the linear partial differential equations along with the simply supported boundary condition. The effect of span to thickness ratio, radius of curvature to span ratio, stacking sequence, power index are investigated. The accuracy of the solution is checked by the convergence study of non-dimensional central deflection and moments. Present results are compared with those available in the literature.

• The Korean Journal of Malacology
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• v.8 no.1
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• pp.21-28
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• 1992

Field investigations were made in 1991 and 1992 in Kwangju and the western and central Chonnam area to determine the distribution of Lymnaea viridis, the intermediate host of Fasciola hepatica, and to study their life history during the different seasons. It had a wide distribution, existing all over the places, and the principal habitats of the snail were rice paddies. The life cycle was determined by making frequent visits to a series of habitats. The snsils began to produce egg masses in April, and egg production was the highest in May and June. Egg laying was continued but decreased in summer. There was sudden decrease in egg production in October when the temperature was below 2$0^{\circ}C$. The number of snails in July. Under the unfavourble conditions the snail either crawle up on the snail to aestivation. At low temperature below 8$^{\circ}C$ the snails hibernated inthe mud of the habitat. It was found in some habitats thao the snails were loving together with L. auricularia and Physa s pp. which indicates the neccessity of differentiation among them.