• Bulletin of the Korean Chemical Society
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• v.19 no.6
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• pp.667-671
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• 1998

A series of 1-aryl-lH-pyrazolo[4,3-c]quinolines and 2-aryl-2H-pyrazolo[4,3-c]quinolines are prepared by reacting 3-acyl-4-chloroquinolines in ethanol or 3-acyl-4(lH)-quinolone in acetic acid with appropriate hydrazines as possible anti-ulcer agents. A regiospecific synthesis of 1-aryl-lH-pyrazolo[4,3-c]quinolines is also achieved. The central pyridine ring could be easily reduced by catalytic hydrogenation.

• Bulletin of the Korean Chemical Society
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• v.11 no.3
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• pp.245-248
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• 1990

A series of compounds were synthesized that contain varying number of mesogenic units, 4-n-butylazobenzene moiety, attached to the central benzene ring through ester bond. These compounds were subjected to thermal analysis on a differential scanning calorimeter (DSC) and also on a polarizing microscope. It was found from this study that the presence of mesogenic units in a multi-mesogenic compound does not guarantee for the compound to become mesomorphic and that the linear molecular shape is conducive to form a liquid crystalline phase.

• 한국해양학회지
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• v.29 no.3
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• pp.248-257
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• 1994

Growth rates of two manganese nodules collected in the Korea Deep Ocean Study (KODOS-89) site in the Clarion-Clipperton Fracture Zones in the central Equatorial Pacific have been estimated by employing uranium-series disequilibrium techniques to investigate the geochemical processes leading to the formation of deep-sea nodules. the growth rates estimated from the profiles of excess /SUP 230/Th activities and ratios of excess /SUP 230/Th to /SUP 232/Th to /SUP 232/Th are in the order of a few millimeters per million years. Growth rates at bottom-side of nodules are 2-3 times faster than those at top-sides. Diagenetic supply of manganese could explain the faster growth at the bottom-side of nodules.

• Journal of the Korean earth science society
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• v.37 no.6
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• pp.359-372
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• 2016

The time-series of Walker circulation index (WCI) in this study shows the strengthening of the Walker circulation in recent years. To further understand the large-scale features related to the WCI strengthening, a difference between the averaged meteorological variables in two time periods 1999-2013 and 1984-1998 is analyzed. The difference in 850 hPa stream flows between the two periods shows that the anomalous easterlies (anomalous trade wind) are dominant due to the strengthening of anomalous anticyclonic circulations at the subtropical Pacific of both hemispheres. The difference between the averaged zonal atmospheric circulations over $5^oS-5^oN$ in the two periods confirms that upward flows are strengthened at the tropical western Pacific and downward flows are strengthened at the tropical central and eastern Pacific in recent years. It matches the WCI strengthening in recent years. The time-series of tropical cyclone (TC) genesis frequency from July to September shows that a mean TC genesis frequency from 1999-2013 decreases compared to that of the time period 1984-1998. The monsoon trough in the period 1984-1998 was located in the further east direction and stronger than that in the period 1999-2013. TCs in the recent period that are generated in further west than TCs in the past period moved from the west. Thus, the TC intensity along the coasts in East Asia becomes weaker in recent period. The intensification of Walker circulation in recent years is related to the weaker TC intensity in East Asia through strengthened anomalous anticyclones at the subtropical western Pacific.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.15 no.3
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• pp.521-527
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• 2011

POWER PC series are common to the Central Processing Unit for Military Single Board Computer. Among them, G4 group, which contains the 74xx series supported by Freescale manufacturer is mainly used in the Military applications. We focus on the Interface between memory and controller. PCB stacking method, component routing, impedance matching and harsh environment for Military spec are the main constraints for implementation. Also, we developed memory as a module for the consideration of Military environments. The overall type of SBC should be designed by the form of 6U VME or 3U VME. Therefore this study suggests the electrically optimum Interface matching, Artwork technology based on the signal cross over and PCB stacking method on the harsh environment.

• Journal of dental hygiene science
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• v.10 no.1
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• pp.25-29
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• 2010

This study was to estimate the effect of herbal medicines on periodontal disease. To screen effective materials for periodontal disease, we performed a series of test for 15 herbal medicine extracts. MIC test for P. gingivalis, IL-$1{\alpha}$ inhibition test, MMP-1 inhibition test and SOD activation test were carried out for herbal medicine extracts, respectively. The results are as followings : 1) Eunhang, Youkdoogu, Daewhang, Hoobak, Goojulcho, Yongacho, Mokhyang, Sesin, Sancho and Hoehyang extracts were effective for reduce P. gingivalis, 2) Eunhang, Jacyak, Youkdoogu, Hagocho, Hoobak, Guaru and Sanyak extracts showed high IL-$1{\alpha}$ inhibition rates, 3) Eunhang and Youkdoogu extracts have effects on MMP-1 inhibition, 4) Eunhang, Sanyak and Youkdoogu extracts effectively activate SOD. Especially, Eunhang extract has high performance through all estimations and can effectively prevent and treat periodontal disease.

• Korean Journal of Applied Biomechanics
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• v.20 no.1
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• pp.67-73
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• 2010

The purpose of this study was to compare the differences in kinematic and kinetic parameters of the ankle and knee joint according to three landing direction(central, left, right). Fifteen collegiate male athletes(age: $22.7{\pm}3.5$ years, height: $174.9{\pm}7.1\;cm$, weight: $69.4{\pm}6.7\;kg$) with the right leg as dominant were chosen. The subjects performed series of drop landings in three directions. In terms of the three different landing directions, plantar flexion was the greatest during the central drop landings. For each initial contact of the landing direction, plantar flexion of the ankle was greatest at the central drop landing, inversion of the ankle was greatest at the right landing and valgus of the knee was greatest at the left drop landing. Regarding the peak force, the greatest was at the 1st peak force during the central drop landing. For the time-span of the 2nd peak force and the 2-1 peak force, both right sides resulted as the greatest. Therefore, with the appropriate training in landing techniques and developing neuromuscular training for proprioception by taking the injury mechanisms on ankle and knee during drop landings into account, it will assist in preventing such injuries.

• Bulletin of the Korean Chemical Society
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• v.28 no.12
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• pp.2241-2247
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• 2007

A new series of chiral bent-shaped liquid crystals with an asymmetric central core based on 1,6- dihydroxynaphthalene and chiral terminal chain prepared from (S)-(?)-2-methyl-1-butanol, 1,6-naphthalene bis[4-(4-alkoxyphenyliminomethyl)]benzoates [N(1,6)-n-O-PIMB(n-2)*-(n-4)O (n = 8-11)] were synthesized. Their mesomorphic properties and phase structures were investigated by means of electro-optical, polarization reversal current, and second harmonic generation measurements in order to confirm the relationship between the molecular structure and phase structure. All odd n (n = 9 and 11) compounds, N(1,6)-9-O-PIMB7*-5O and N(1,6)-11-O-PIMB9*-7O exhibit antiferroelectric phase, whereas even n (n = 8 and 10) compounds was flexible, N(1,6)-10-O-PIMB8*-6O exhibits the ferroelectric phase but N(1,6)-8-O-PIMB6*-4O exhibits the antiferroelectric phase. These results come from the decrease of the closed packing efficiency within a layer and the lack of uniform interlayer interaction between adjacent layers, which were caused by the asymmetrical naphthalene central core. Thus, we concluded that the structure of central core as well as the terminal chain plays an important role for the emergence of particular polar ordering in phase structures.

• Proceedings of the KOSOMBE Conference
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• v.1993 no.11
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• pp.40-43
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• 1993

Electronic fetal monitoring system is an easier ar d usual method in various prenatal and labor period fetal surveilence methods currently in use. But there haven't been enough cases of using the central monitoring system despite the fact that the bedside fetal monitoring system have already been widely in use in Korea as an essential medical equipment item. We have developed more efficient central fetal monitoring system based on the personal computer with the visual maternal monotoring device using infrared camera which processes the signals from existing bedside fetal monitoring systems such as H/P's 8040 series. And we have performed the clinical application on 41 pregnant women and the results were satisfactory. In conclusion, more efficient and familial fetal monitoring is possible with our PC based central fetal monitoring system which provides the medical personnel with the view of a selected pregnant woman on the same screen where the electronic waveforms and data are displayed.

• CELLMED
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• v.9 no.4
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• pp.8.1-8.5
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• 2019

Introduction: Psoriasis is a major health concern around the world. Physicians of the Unani system of medicine have been treating psoriasis for centuries. Aim: The purpose of our study was to assess the effect of Majoon Mundi (a semisolid Unani medication intended for oral intake used as blood purifier) and Qairooti Karnab (a Unani medication in paste form intended for topical application used as emollient) in the treatment $na{\ddot{i}}ve$ psoriasis cases and to collect data to warrant further clinical trials. Material and Methods: Psoriasis cases were diagnosed clinically. Data were collected during treatment of five patients of psoriasis treated with the Majoon Mundi (oral intake of 5 gm twice daily with 200 ml of water for 12 weeks) and Qairooti Karnab (topical application on affected sites twice a day for 12 weeks). Patients were treated for 12 weeks. Treatment response was seen with clinical improvement in skin lesions and measurement of Psoriasis Area and Severity Index (PASI Scoring) before and after treatment. Results: Reduced PASI Score was observed in all five patients after 12 weeks of treatment [PASI before and after treatment was (mean${\pm}$SD) $20.7{\pm}4.6$ vs. $3.2{\pm}1.8$; p-value <0.05.]. Clinical improvement was noticed within an average of 4 weeks of treatment. Conclusion: Preliminary findings indicate the potential therapeutic role of Majoon Mundi and Qairooti Karnab in the treatment of psoriasis. Clinical trials based on this Unani pharmacopeial formulation should be conducted to explore the therapeutic potential of this formulation in psoriasis