• The Journal of the Korea Contents Association
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• v.13 no.10
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• pp.266-277
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• 2013

Climate change asks the government to make changes in water management system. Although water demand is increasing according to urbanization, clean and safe water supply is limited. Therefore efficient water management is one of the key issues. Korean water management system is evaluated inefficient because it is executed by five different ministries. This study reviewed previous literature about Korean water management system, analysed present function sharing among 5 ministries, and conducted survey on improvement of water management system. Experts recognized that the most important problem of water policy is the failure of policy coordination among Ministries, and the solution of it is to make a new integral organization or to integrate related functions into one Ministry. Based on them, this study conclude that the central government functions related with water management need to be integrated on a new organization or Ministry of Environment focused on water quality improvement in the light of preservation instead of development.

• BMB Reports
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• v.39 no.4
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• pp.339-345
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• 2006

The blood-neural barrier (BNB), including blood-brain barrier (BBB) and blood-retinal barrier (BRB), is an endothelial barrier constructed by an extensive network of endothelial cells, astrocytes and neurons to form functional 'neurovascular units', which has an important role in maintaining a precisely regulated microenvironment for reliable neuronal activity. Although failure of the BNB may be a precipitating event or a consequence, the breakdown of BNB is closely related with the development and progression of CNS diseases. Therefore, BNB is most essential in the regulation of microenvironment of the CNS. The BNB is a selective diffusion barrier characterized by tight junctions between endothelial cells, lack of fenestrations, and specific BNB transporters. The BNB have been shown to be astrocyte dependent, for it is formed by the CNS capillary endothelial cells, surrounded by astrocytic end-foot processes. Given the anatomical associations with endothelial cells, it could be supposed that astrocytes play a role in the development, maintenance, and breakdown of the BNB. Therefore, astrocytes-endothelial cells interaction influences the BNB in both physiological and pathological conditions. If we better understand mutual interactions between astrocytes and endothelial cells, in the near future, we could provide a critical solution to the BNB problems and create new opportunities for future success of treating CNS diseases. Here, we focused astrocyte-endothelial cell interaction in the formation and function of the BNB.

• Progress in Medical Physics
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• v.11 no.1
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• pp.1-18
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• 2000

For wedged photon beams, the variation of the wedge factor with field size was reported by several authors. However, until now such variation with field size had not been explained quantitatively. Therefore, the variation of the wedge factor was investigated by measuring outputs with field sizes increasing from 4 cm $\times$ 4 cm to 25 cm $\times$ 25 cm for open and wedged 6 and 10MV X-ray beams. The relative outputs for wedged fields to 10 cm $\times$ 10 cm have been obtained. The results show the Increase of the wedge factor caused by the change in fluence of high energy Photon beam with field size, up to 8.0% for KD77-6MV X-ray beam. This increase could be explained as a linear function of the irradiated wedge volume except small field size up to about 10 cm. In the cases of the narrow rectangular beam parallel to the wedge direction, the wedge factor decreases slightly with increasing field size up to about 10-15 cm due to a relatively reduced photon fluence from the change of the wedge thickness. We could explain the causes of a wedge factor variation with field size as the fluences of primary photon passed throughout the wedge, contributing to the dose at the central beam axis and that the fluences were affected by the gradient of the wedge with the change of field size. For clinical use, the formula developed to describe the wedge factor variation with field size has been corrected.

• Development and Reproduction
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• v.9 no.1
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• pp.1-5
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• 2005

The hypothalamo-pituitary-gonadal hormone axis is centrally controlled by a complex regulatory network of excitatory and inhibitory signals, that is dormant during infantile and juvenile periods and activated at puberty. The kisspeptins are the peptide products of the KiSS-1 gene and the endogenous agonists for the G protein-coupled receptor 54(GPR54). Although KiSS-1 was initially discovered as a metastasis suppressor gene, a recent evidence suggests the KiSS-1/GPR54 system is a key regulator of the reproductive system. Yet the actual role of the KiSS-1/GPR54 system in the neuroendocrine control of gonadotropin secretion remains largely unexplored, the system could be the first missing link in the reproductive hormonal axis. Central or peripheral administration of kisspeptin stimulates the hypothalamic-pituitary-gonadal axis, increasing circulating gonadotropin levels in rodents, sheep, monkey and human models. These effects appear likely to be mediated via the hypothalamic GnRH neuron system, although kisspeptins may have direct effects on the anterior pituitary gland. The loss of function mutations of the GPR54(GPR54-/-) have been associated with lack of puberty onset and idiopathic hypogonadotropic hypogonadism(IHH). So kisspeptin infusion may provide a novel mechanism for HPG axis manipulation in disorders of the reproductive system.

• Development and Reproduction
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• v.13 no.2
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• pp.79-87
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• 2009

Due to its well-known function in parturition and milk ejection, oxytocin (OT) has been considered as a 'female neurohypophyseal hormone'. Recent studies, however, clearly indicate that OT has some local roles in male reproduction via both central and peripheral routes. In experimental rodents, OT is released within distinct brain regions in response to social stimuli, and the brain OT receptor (OTR) mediated actions were strongly involved in the regulation of a variety of male behaviors such as mating-associated behaviors. In particular, OT and/or OTR knockout mice provide important clues about the molecular regulatory mechanism of the socio-sexual behaviors. Several lines of evidence also show that OT is synthesized within rodents testis, epididymis and prostate, and the presence of OTRs in these organs. In rodent testes, OT might have a role in the modulation of steroidogenesis via stimulation of the conversion of testosterone (T) to dihydrotestosterone (DHT) by 5alpha-reductase. Similar effects of OT on this androgen conversion were observed in epididymis and prostate suggesting the OT's modulatory role, such as contractility induction, in these androgen-dependent organs. In this context, further investigations on the OT's role in male CNS and reproductive organs are likely to provide better understanding on the complex socio-sexual behaviors and a platform for development of therapeutics to treat some psychological and/or andrological problems.

• Journal of Conservation Science
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• v.30 no.2
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• pp.111-122
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• 2014

In Bongseon-ri site, the central type and the local type of the Baekje tombs co-exist together. Many swords with ring pommel which to regional leaders in Seocheon the Beekje government granted are excavated from these tombs. These represent that the regional leaders were controlled by the Baekje government gradually. Four swords with ring pommel and one simple sword are investigated metallurgically and we seek what swords have a function of weapon or what sword produce for grave goods. The simple sword is made by solid carburizing technology and quenching of heat treatment so it's possibly used as a weapon. In contrast, four swords with ring pommel has little chance of weapon because the blade of swords consists of microstructure that have low hardness and the back of swords don't have microstructure can absorb the shock. The most identical characteristic of the simple sword and swords with ring pommel is that they are possible to classify clearly into practical/non-practical tools. Additionally, according to non-metallic inclusion analysis result of these swords, w$\ddot{u}$stite and glass phase are found together. Thus, it is able to say that reduction method in low temperature is applied during smelting process.

• Korean Journal of Environmental Agriculture
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• v.25 no.4
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• pp.316-322
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• 2006

Objective of this research was to assess the release characteristics of metals from the mine tailing to base the prediction of metal load potential from tailing to soils. Water-soluble concentrations of Cd, Cu, Pb and Zn released from mine tailing after 2 hrs were 2.31, 129.38, 17.17, and 287.53 mg/kg, respectively, as compared to 1.6, 128, 108, and 142 mg/kg that were extractable by 0.1 M HCl. Kinetics of metal releases followed the power function model significantly indicating that more of water soluble fractions of those metals released at the initial short time, followed by a slow increase. Concentrations of metals released from tailing by water and 0.1 M HCl were in the orders of Zn > Cu > Pb > Cd. The breakthrough curve from the column experiment showed that concentrations of Cd, Cu, and Zn reached at highest after one pore volume, but that of Pb reached highest after five pore volumes when 0.1 M HCl was used as eluent. The release rate of Cd from mine tailing was the fastest but Pb was the slowest. The cumulative mass of metal released by 0.1 M HCl was in the order of Zn > Cu > Pb > Cd after nine pore volume elution.

• Archives of design research
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• v.16 no.2
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• pp.385-394
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• 2003

Modem market's tendency is displaying brand strategy of Corporation sells product and consumer buys rand'.Brand acts by intermediate that reflect consumer's request and experience and attach product and consumer hat produce. Successful brand intended strategy empirical esthetics enemy, and consumer recognizes brand to novel experience and think by one fixed idea (awareness). any corporations wish to get maximum effect into minimum investment expense that reduce huge public elations and advertisement charge. Do to incuse impression for product brand through direct interview with consumer at purchase visual point, and do function hat drive purchase and the importance great rawly. Therefore, sight expression of brand image must be able to from immobile one impression in consumer's spirit being inked nearly with brand .Brand that situate by affirmative impression once can arrive in purchase by brand without alternative information being withdrawn by consumer's emory. Solution of visual expression for this being city cornification laying stress on logo and mark of brand as central element of brand image, speak as communication actor who back this. This to be Dija as direction that product and connection are deep before meaning that is sight language enemy who allow fetters special quality and the seniority in age sex language enemy of brand as ell as have direction of by methods method for problem solution present can .Therefore, relation with brand image analysis of sports equipment and consumer product purchase that this research forms market economy theoretical investigating to be effective and present direction that is image-making to be consistency this the purpose be.

• Journal of Korean Ophthalmic Optics Society
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• v.16 no.1
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• pp.1-5
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• 2011

Purpose: Measurement of the horizontal and vertical prism diopter was investigated which was occurred due to distance differences between the optical inter-centeral distance (OC) and the interpupillary distance (PD) of the prescribed glasses. Methods: We surveyed 96 subjects (192 eyes) at the average age of 21.56 years old. The PD was measured by using the PD measurement system (DONGYANG PD-85, Korea), and the OC of the glasses was measured by using the projective peak refractive power measurement system (TOPCON CL-200, Japan). The OH value was measured by using Penlight and the PD ruler. Results: The PD which had been measured by the PD system and the OC of the glasses revealed 78.1% of differences. 62.5% of the objects were base-in value prescribed glasses; 58.3% were out of permissible error. Only 8 subject showed concurrence between the prescribed glasses and the OH value, and 82.3% of the objects were induced vertical prism of over 1 (prism diopter). Conclusions: In order to improve the vision function of people who wear glasses, it is necessary to advance the accuracy of PD, OH measurement and making glasses as well.

• Journal of Korean Ophthalmic Optics Society
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• v.12 no.1
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• pp.1-7
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• 2007

To investigate the momentary movement pattern of soft contact lens(SCL) depending on wearing time, eight types of soft contact lenses were worn by 10 normal subjects and the momentary movements of SCLs were estimated using by high speed camera(FASTCAM ultima 1024). When the momentary movements of SCLs in the cornea between blinkings were compared after 15 min wearing, the vertical movements of all eight SCLs were about 2 times larger than the horizontal movement but the extent of these movement difference was a function of kinds of SCLs. The momentary moving distance of SCL varied from the kinds of SCLs, which A and B lens, daily wear lens, moved significantly larger distance compared with other SCLs. The momentary movements between blinkings decreased significantly after 8hr wear of SCLs. The extents were different when SCLs were compared with each other, which the reduction range of horizontal and vertical movement was 24.6~60.0% and 20.4~94.3%, respectively. The A, B and C lenses which had relatively higher water content showed the larger movement reduction after SCL wear. This results suggest that wearing SCL for some hours decreases the movement of SCl, which can induce the change of tear flow.