• Archives of Plastic Surgery
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• 제42권4호
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• pp.469-474
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• 2015

Background Many methods have been proposed for the correction of sunken upper eyelids. These methods include surgical treatments, such as micro-fat, dermofat, or fascia-fat grafts, or the use of alloplastic materials. Here, we present our experience of sunken upper eyelid correction involving the simple addition of anchoring the central fat pad to the medial fat pad during upper blepharoplasty. Methods We performed 74 cases of upper blepharoplasty with sunken upper eyelid correction between October 2013 and September 2014. The lateral portion of the central fat pad was partially dissected to facilitate anchoring. The medial fat pad was gently exposed and then pulled out to facilitate anchoring. After the rotation of the dissected lateral portion of the central fat pad by $180^{\circ}$ to the medial side, it was anchored spreading to the medial fat pad. Photographs taken at 6 months postoperatively were presented to three physicians for objective assessment. Of the 74 patients, 54 patients followed at 6 months postoperatively were included in this retrospective, objective assessment. Results Sunken eyelids were effectively corrected in 51 of the 54 patients, but 3 had minimal effect because preaponeurotic fat pads had been removed during previous upper blepharoplasty. In addition to correcting sunken eyelids, lateral bulging was corrected and a better definition of the lateral portion of upper lid creases was obtained. Conclusions Anchoring the central fat pad to the medial fat pad provides an effective means of correcting sunken upper eyelids during upper blepharoplasty.

• Journal of Nutrition and Health
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• 제25권7호
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• pp.628-641
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• 1992

To investigate the effects of exercise-training on fat distribution several indicators of body fatness(percent body fat skinfolds thickness body circumference) were assessed in 128 healthy male subjects submitted to an 8-wk high intensive exercise-training. The subjects(average age=20.3$\pm$1.3 yrs) exercised 5 days/week. Daily energy intake and expenditure wee recorded. The results obtained are summarized as follows : 1) Through exercise-training lean body mass increased significantly (changes : 0.5$\pm$1.5kg; p=0.000) decreased significantly. 2) Suprailiac was the most reduced site by exercise-training among eight site skinfolds. Central skinfolds were changed more by exercise-training than peripheral skinfolds with reduction of 1.7$\pm$2.1mm and 0.4$\pm$1.8mm respectively. Central site circumferences were reduced more by exercise-training than peripheral site circumferences. 3) As a result of analyzing 12 of the fattest(top 10% of weight) and 12 of the leanest men(bot-tom 10% of weight) it indicated that there was a significant reduction of fat tissue in body composition and skinfolds thickness for the fat group. However there was no significant change for the lean groups. 4) Correlational analysis showed that predicting changes in body fat by infrared(NIR) measurement seemed to be closely associated with changes in body fat by Kim's equation and Katch's equation in young men.

• International Journal of Industrial Entomology and Biomaterials
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• 제2권2호
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• pp.149-153
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• 2001

The influence of baculovirus Bombyx mori Nuclear Polyhedrosis virus (BmNPV) infection on intermediary metabolic pathways in silkworm Bombyx mori L. was investigated. Studies revealed that NADP-linked malate dehydrogenase activity in hemolymph of infected silkworms at 96 hrs post infection (p.i.) with visible symptoms of infection was enhanced in comparison to healthy larvae of the same age. Also, NADP-dependent MDH activity was significantly lower in fat body cytosol of infected larvae at 96 hrs p.i. when compared to healthy larvae. Similarly, some biometabolic parameters like growth, protein content and cholesterol titer were observed to be influenced by baculovirus infection. While the growth of infected larvae was significantly retardedi protein content was also drastically reduced in both hemolymph and fat body tissues. Cholesterol titers however, was enhanced in infected larvae. The results observed herein point to a significant change in the normal biochemical and biometabolic pathways required for growth and development following BmNPV infection.

• Journal of Nutrition and Health
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• 제23권4호
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• pp.257-269
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• 1990

We designed this study to compare the total body fat content and its distribution of diabetics with those of normal subjects. Skinfold thicknesses at eight sites(subscapular, subcostal, abdomen, suprailiac, triceps, forearm, thigh and calf) and body circumferences at five sites(waist, hip, arm, thigh and calf) were measured on 220 diabetics(82 male, 138 female) and on 160 nondiabetic subjects(male 57, female 103). We matched 92 pairs with diabetics and nondiabetic control subjects by sex, age, body weight and height, and made comparisons between two groups(case-control study). The results were as follows: 1) There was no significant difference in total body fat content of diabetics and control (male ; 20.40$\pm$2.12%, 19.20$\pm$3.52%, female ; 26.46$\pm$2.53%, 27.01$\pm$2.92%, respectively). However, body muscle mass(%) in diabetic men(33.37$\pm$4.19%) was significantly lower than in nondiabetic men(38.16$\pm$7.11%). 2) Diabetics, especially women, were characterized by more central body fat than control. That is, indices of centrality of body fat distribution(subscapular/triceps skinfold : STR, central/peripheral fat : CPR) of diabetics were higher than those of control. 3) Body weight, body mass index and %IBW(current body weight$\times$100/ideal body weight) had negative correlations with duration of diabetes(r=-0.23~-0.33), but total body fat content(%) and indices of body fat distribution, such as STR, CPR, waist/hip girth ratio(WHR), and waist/thigh girth ratio(WTR), were not related to duration of diabetes.

• 한방비만학회지
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• 제1권1호
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• pp.1-11
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• 2001

Obesity is a metabolic disease associated with multiple hormonal abnormalities. Therefore, obesity management aims at balancing these endocrine malfunctions nowadays. Although many studies proved interactions of hormones related with obesity, there are still lots of controversies. Most of these malfunctions are more pronounced in central, visceral obesity than in peripheral obesity. Recently, it is revealed that a central lesion of endocrine malfunction in human visceral obesity is probably related with a hypersensitivity of hypothalamopituitary-adrenal(HPA) axis. Probably associated with this axis, Insulin and cortisol promote lipid accumulation by expressing lipoprotein lipase activity, while sex hormones and growth hormone exert the opposite effects. Also reviewed was thyroid hormone which is closely related with thermogenesis. Serotonin is prescribed as antidepressant and it is applied to some eating disorders. Recently, leptin made in fat deposit also took attentions in terms of regulator of appetite and messenger of sex signal.

• Journal of Yeungnam Medical Science
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• 제40권2호
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• pp.207-211
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• 2023

Fat embolism syndrome is a rare but alarming, life-threatening clinical condition attributed to fat emboli entering the circulation. It usually occurs as a complication of long-bone fractures and joint reconstruction surgery. Neurological manifestations usually occur 12 to 72 hours after the initial insult. These neurological complications include cerebral infarction, spinal cord ischemia, hemorrhagic stroke, seizures, and coma. Other features include an acute confusional state, autonomic dysfunction, and retinal ischemia. In this case series, we describe three patients with fat embolism syndrome who presented with atypical symptoms and signs and with unusual neuroimaging findings. Cerebral fat embolism may occur without any respiratory or dermatological signs. In these cases, diagnosis was established after excluding other differential diagnoses. Neuroimaging using brain magnetic resonance imaging is of paramount importance in establishing a diagnosis. Aggressive hemodynamic and respiratory support from the beginning and consideration of orthopedic surgical intervention within the first 24 hours after trauma are critical to decreased morbidity and mortality.

• Food Science and Biotechnology
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• 제17권4호
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• pp.700-704
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• 2008

Anti-obesity effects of $\beta$-cyclodextrin in obese C57BL/6J mice induced by a high fat diet (HD) were observed. The administration of $\beta$-cyclodextrin reduced the gain of body weight, abdominal fat, liver weight, the lipid deposits of hepatocytes and the size of adipocytes in the HD group. In serum analysis, the total and low-density lipoprotein-cholesterols were significantly decreased in the $\beta$-cyclodextrin-supplemented HD group than in the HD group. However, high-density lipoprotein-cholesterol was not changed in these groups. In hypothalamic homogenates, the decrease of neuropeptide Y and increase of $\alpha$-melanocyte stimulating hormone were detected in the $\beta$-cyclodextrin-supplemented HD group compared to that in the HD group. These effects of $\beta$-cyclodextrin were similar to those of Garcinia cambogia, which is widely used as a natural anti-obesity product. These results suggest that $\beta$-cyclodextrin has anti-obesity effects through the lowering of the abdominal fat pad and inhibits the central effects of hunger.

• Journal of Preventive Medicine and Public Health
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• 제24권1호
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• pp.57-69
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• 1991

중심성 지방분포와 고혈압과의 관계와 비근 내측 피부두께가 기존의 말초성 지방분포를 나타내주는 삼두근 피부두께에 비해 더 우수한 지표가 되는지를 알아보기위해서 1990 년 해군수중 근무자 특수신체검사자 중에서 450 명을 연구자의 편의에 의해 추출되었다. 대상자의 평균 연령이 27.9 세였고 범위가 19-51세었다. 말초성 지방분포의 지표로 삼두근과 비골 내측 피부두께를, 중심성 지방분포는 견갑골하 피부두께와 이것과 삼두근으로 이루어진 비와 차이로 측정을 했다. 신체의 지방분포를 나타내는 피부두께와 이 들을 기준으로한 비와 차이의 지수를 4 분위수로 나누어 첫 1/4 분위수를 기준으로 하고 나머지 3 가지 수준을 기준에 비교를 했다. 연령과 전체적인 비만도를 다중지수분석으로 통제를 한 후 고혈압과의 관계에서 견갑골하 피부두께가 기준인 1/4 분위수와 비교해 보아 2/4, 3/4, 4/4 분위수로 증가함에 따라 각각 2.05(95 % 신뢰구간 1.18-3.59), 2.02(1.06-3.86), 4.00 (1.99-8.06) 의 유병비차비를 보였다. 견갑골하 피부두께와 비골 내측 피부두께의 차이 역시 4/4 분위수가 되었을 때만 2.45 (1.28-4.68)의 비차비를 보였다. 그 외의 삼근 피부두께와 비근내측 피부두께에서는 기준에 비교해 보아 1 을 포함하지 않은 비차비는 없었다. 연령과 전체적인 비만도를 조정한 비차비는 조정치 않은 조비차비에 비해 대체적으로 조금 감소했다. 비근 내측의 피부두께는 삼두근 피부두께에 비교해보아 더 우수한 말초성 지방분포를 대표해주는 피부두께로 보였다. 이러한 결과는 전체적인 비만도 수준과는 독립적으로 견갑골하 피부두께로 측정된 중심성 지방분포가 고협압과 관계가 있으며 우수한 중심성 지방분포를 나타내주는 지표가 됨을 시사해주는 소견이다.

• Archives of Plastic Surgery
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• 제44권6호
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• pp.559-563
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• 2017

Supported by recent literature on the signs of aging of the middle and lower face, our clinical research has documented a loss of volume of the deep structural components of the central face and a progressive descent of the nasolabial fat and the jowl fat, leading to facial fragmentation. The signs that appear around the age of 45 to 50 years are well targeted by the mini-invasive technique described here. We focused on refitting the jowl fat and the nasolabial fat associated with cutaneous tightening. The use of absorbable barbed sutures (Quill) led to significant improvements, enabling the fitting of fat on fat. In the past 4 years, 167 operations were performed using this technique. The clinical results were very satisfactory, yielding a natural effect caused by the mobilization and strong fixation of the nasolabial fat and the jowl fat in the direction opposite to their displacement.

• 대한지역사회영양학회지
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• 제1권3호
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• pp.405-422
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• 1996

The purpose of this study is provide reference data for anthropometry and body composition and also to compare body fat estimation among skinfold thickness, BIA and NIR methods. Anthropometric measurements of height, weight, eight sites of skinfolds and six sites of circumferences were taken from 76 elderly male and 153 elderly female. Skinfold thicknesses, body composition and circumferences except waist were lowered with advancing age in elderly females and males. The degree of change with age vaired among parameters but was consistently and significantly(p<0.05) greater in elderly females than I males. Although sum of skinfold thicknesses and the amount of central and peripheral fat were significantly higher in females than that of males, the ratio of central fat to peripheral fat was significantly greater in males than in females. WHR is also significantly higher in males than that of females. This indicates that fat distribution of males tend to be centralized toward the trunk of the body than females. Estimation of body fat from skinfold thickness(male : 18.5$\pm$4.1$\%$, female : 29.7$\pm$4.0$\%$) and BIA(male : 19.5$\pm$7.3$\%$, female : 29.6$\pm$6.7$\%$) were similar but were significantly different from NIR method(male : 24.7$\pm$5.6$\%$, 34.8$\pm$4.9$\%$). Estimation of body fat by NIR measurement seemed to be more overestimated. Understanding the normal changes in body composition with increasing old age, and the ability to measure these changes and compare them with appropriate reference data are important for the health of the elderly.