• Korean Journal of Applied Biomechanics
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• v.16 no.1
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• pp.55-63
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• 2006

The purpose of this study is to prove the kinematical characteristics of Deff motion, the high bar performance, in terms of flying phases so that we can provide basic sources for improving gymnastic performance. To do this, we selected and analyzed the performance of two athletes who did Deff motion in the high bar competition of male artistic gymnastic in the 22nd Universiade 2003 Daegu. We drew the conclusions from the kinematical factors that were came out through analyzing three-dimensional cinematography of the athletes' movements, by using a high speed video camera. To make a successful performance, a performer releases the bar at a height of a high bar vertically and at a height of 82cm horizontally, and the flying performance should be made without moving forward, as maintaining the proper balance, in order to rise over 118cm high during the flying phase. When the performer is releasing the bar, an increase of the vertical speed in the center of the body and extension of a knee joint and a hip joint contribute to increasing a flying height. And when the moving body is twisted, leaning to left side is caused by the winding movement of a knee joint, which causes an unstable bar grasp. To grasp the bar stably, just before releasing the performer should gain propulsive force from twisting rotation through increasing the speed of shoulder rotation. And before the peak point, the performer should make sure of a body rotation distance over $164^{\circ}$ so that he or she can do an aerial rotary performance smoothly. When grasping the high bar, the center of the body should be above the bar and the angle of shoulder rotation should be maintained close to $540^{\circ}$ simultaneously. he high point performance(S1) has more speed on an ascending phase and less speed on a descending phase than the low point performance (S2). At the peak point, both the rotation angle of the body and that of the shoulder in high point performance are big as well. In conclusion, it is shown that a performer can make a jump toward the high bar easily with the body straight because the performer can hold the upper part of the body erect early in a descending phase.

• Journal of Life Science
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• v.29 no.8
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• pp.904-915
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• 2019

Prostate cancer (PCa) is one of the most metastatic tumor. Although hormone therapy or surgical castration is mostly conducted to treat PCa, it has a lot of side effects. Recently, many researchers have been exploring the tumor microenvironment to remedy these circumstances. Immune cells, especially macrophages, are an important composition of the tumor microenvironment. Under normal conditions, macrophages exhibit mild tumoricidal activity against tumors. However, once activated by interferon gamma or lipopolysaccharides, macrophages can kill cancer cells directly or indirectly by secreting cytokines and chemokines. In this study, murine macrophage RAW 264.7 cells were treated with Phellinus linteus extract. To analyze their pro-inflammatory phenotype, we were used several assays such as a real-time polymerase chain reaction, an enzyme-linked immunosorbent and nitric oxide assay. Prostate cancer cells were treated with the RAW 264.7-conditioned media, which was identified as a pro-inflammatory nature, for 48 h, and the expression of epithelial-mesenchymal transition (EMT)-related genes was determined. Not only N-cadherin, Snail, Twist, Slug, and Cadherin 11, which are mechenchymal-related proteins, were decrease, but epithelial marker of E-cadherin was increased. In addition, the mRNA level of vimentin, ccl2, and vegfa were decreased, as the EMT is closely related to the migration and invasion of cancer cells. In conclusion, the RAW 264.7-conditioned media stimulated with P. linteus extract inhibited migration and invasion and regulated the EMT pathway in human prostate cancer cells.

• BMB Reports
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• v.52 no.10
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• pp.595-600
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• 2019

Cardiac fibrosis is a common feature in chronic hypertension patients with advanced heart failure, and endothelial-to-mesenchymal transition (EndMT) is known to promote Angiotensin II (Ang II)-mediated cardiac fibrosis. Previous studies have suggested a potential role for the transcription factor, ETS-1, in Ang II-mediated cardiac remodeling, however the mechanism are not well defined. In this study, we found that mice with endothelial Ets-1 deletion showed reduced cardiac fibrosis and hypertrophy following Ang II infusion. The reduced cardiac fibrosis was accompanied by decreased expression of fibrotic matrix genes, reduced EndMT with decreased Snail, Slug, Twist, and ZEB1 expression, as well as reduced cardiac hypertrophy and expression of hypertrophy-associated genes was observed. In vitro studies using cultured H5V cells further confirmed that ETS-1 knockdown inhibited $TGF-{\beta}1$-induced EndMT. This study revealed that deletion of endothelial Ets-1 attenuated Ang II-induced cardiac fibrosis via inhibition of EndMT, indicating an important ETS-1 function in mediating EndMT. Inhibition of ETS-1 could be a potential therapeutic strategy for treatment of heart failure secondary to chronic hypertension.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.36 no.2
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• pp.73-88
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• 2000

A series of analysis and experiment on the fishing gear and method of the existing midwater pair trawl net with 12,800mm of maximum mesh size is carried out to determine the most effective shape factor. As the first step of this study, the fishing gear and method for the existing net are analyzed to solve problems, such as being low of the net height by increasing the towing speed, twist of net pendant and twine, suspension of float between knots of mesh. etc. Standing on these results, the existing net are modified by very effective shape based on the theory and technology designing the fishing gear. Also, the model experiment is carried out to determine the most effective shape factor of the modified net in the circulation water channel. The obtained results can be summarized as follows : 1. On the length of net pendants(No.2 and No.3) connected with side line, opening efficiency of net with length 8.0cm of net pendant is the greatest and in the order of 11.5cm, 15.0cm. 2. On the number of the net pendant, opening efficiency of net with 4 lines of net pendant is the greatest and in the order of 3 lines, 2 lines. Center part of side panel is pushed out backward, and the pushed length is increasing by increasing flow speed. 3. On the sinking force, opening efficiency of the net is increasing by increasing sinking force. And opening efficiency shows almost the same when sinking force is greater about 1.5 times than that of the existing net in case of the net with 3 lines of net pendant, and about 1.6 ~ 1.7 times than that of the existing net in case of the net with 2 lines.

• Journal of the Korean Wood Science and Technology
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• v.41 no.6
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• pp.535-543
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• 2013

The objective of this study was to analyse the residual stress in Larix kaempferi board during and after kiln-drying. The boards were primarily intended for using as laminar of cross laminated timber (CLT). In this study, the equivalence of moisture content by equalizing treatment was proved and reduction of residual stress by conditioning treatment was quantified. Prong test and slice test were carried out to analyse the residual stress in wood during drying. Transverse casehardening was measured immediately after making prong sample. Residual stress of four parts in wood from surface to center was analyzed quantitatively based on elastic deformation after just cutting slices from board. Tensile stress and compressive stress on the surface of board during drying did not exceed 2.2 MPa when boards were dried by kiln-drying schedule of T10-C4 and T12-D5. Because the tensile strength and compressive strength of transverse direction of Larix kaempferi lumber are 2.65 MPa and 4.60 MPa, application of more severe drying schedule can be recommended. Cup and twist were reduced by about 40% by equalizing and conditioning treatments after drying.

• Journal of the Korean Society of Marine Environment & Safety
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• v.20 no.1
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• pp.11-17
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• 2014

In this study, a hydraulic model experiment under wave conditions was carried out to investigate the gap/distance between two near-unit farm lines that affects the rope kink and shape variation of a seaweed farm during mooring block movement. As a result, rope kink occurred during the low wave height condition as the gap/distance between the two near-unit farm lines decreased. The seaweed farm maintained a stable shape in the higher wave height conditions as the gap/distance between the two near-unit farm lines increased. This result indicates that rope kink is sensitively affected by the gap/distance between the two near-unit farm lines. A tendency to increase the critical wave height was observed when mooring block movement occurred, and as the mooring block weight and wave period increased. From the experimental results in which incident wave conditions and the mooring block weight changed, as the front side mooring block weight increased from 3.0 to 8.0 tons, the seaweed farm was stable, and rear side mooring block movement hardly occurred. The observed tension of the seaside mooring line was a maximum at about 3.0 ton/m.

• Progress in Medical Physics
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• v.26 no.1
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• pp.6-11
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• 2015

The purpose of this study was to analyze the rotational errors of roll, pitch, and yaw in the whole breast cancer treated by the three-dimensional radiation therapy (3D-CRT) using TomoDirect (TD). Twenty-patient previously treated with TD 3D-CRT was selected. We performed a retrospective clinical analysis based on 80 images of megavoltage computed tomography (MVCT) including the systematic and random variation with patient setup errors and treatment setup margin (mm). In addition, a rotational error (degree) for each patient was analyzed using the automatic image registration. The treatment margin of X, Y, and Z directions were 4.2 mm, 6.2 mm, and 6.4 mm, respectively. The mean value of the rotational error for roll, pitch, and yaw were $0.3^{\circ}$, $0.5^{\circ}$, $0.1^{\circ}$, and all of systematic and random error was within $1.0^{\circ}$. The errors of patient positioning with the Y and Z directions have generally been mainly higher than the X direction. The percentage in treatment fractions in less than $2^{\circ}$ at roll, pitch, and yaw are 95.1%, 98.8%, and 97.5%, respectively. However, the edge of upper and lower (i.e., bottom) based on the center of therapy region (point) will quite a possibility that it is expected to twist even longer as the length of treatment region. The patient-specific characters should be considered for the accuracy and reproducibility of treatment and it is necessary to confirm periodically the rotational errors, including patient repositioning and repeating MVCT scan.

• Korean Journal of Heritage: History & Science
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• v.56 no.2
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• pp.80-98
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• 2023

In the late Joseon Dynasty, when the bride would ride a palanquin when she went to live with her in-laws, it was a custom to cover the palanquin with tiger skin to ward off misfortunes that may come her way. The higher classes used tiger skin or leopard skin for this purpose, but the common people had to substitute this expensive item with a tiger pattern painted on a blanket. Such blankets were called hotanja, hogu, hoguyok and the like. The term "hotanja" is a pure Korean word. It is not known when the cover for the bridal palanquin was first used, but it was popular from the end of the 19^th century and then gradually disappeared. This is due to the introduction of new Western style weddings that eliminated the need for a bridal palanquin. The tiger print blanket was used not only to cover the bride's palanquin but also to cover a table or floor during the wedding ceremony. This study ran a material analysis on nine pieces of tiger print blankets. All of the blanket artifacts examined in this study had an outer cover and a lining made of fabric that used cotton thread for the warp and wool thread for the weft. Two kinds of wool were found in the weft thread in the outer covers: fat-tailed sheep hair from China and goat hair for carpets from the Hebei province, China. Records show that "blankets with painted tiger patterns" were imported from Russia, and the imported blankets were from Russia and China. The outer cover can be categorized into six types, and the lining into three types depending on the weave and direction of the thread twist. The hem facing can be divided into four types. The lining and outer cover use the full width of the fabric, which was woven in wide widths of 135 cm or wider. The tiger pattern on the blanket was made by stenciling. The stencil design of the body and tail of the tiger were placed on a red blanket to be painted in white, and then the background color of the tiger, which is yellow, would be painted over the white, and then black stripes would be added. The pattern of the tiger varies, which shows that the blankets were made by various craftspeople. The pattern of the tiger print blanket is usually of a tiger lying down, but there were tiger print blankets with a tiger standing up. The pattern of the tiger grew smaller over time, and flower patterns were added in the background. Decorative elements were gradually added to the tiger print blanket patterns, but its function as a palanquin cover became lost. By taking the features of tiger print blankets into consideration, it can be assumed that there are imported pieces among the remaining pieces, and were produced in various places because it was popular at that time.