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The Effect of Gamisungmagalguntang(加味升麻葛根湯) on Chronic Urticaria Identified as "Wind Heat" Pattern (풍열형(風熱型) 만성 두드러기에 대한 가미승마갈근탕(加味升麻葛根湯)의 치료효과)

  • Hong, Eu-Gene;Kim, Bong-Hyun;Shin, Jun-Hyuk;Nam, Hae-Jeong;Kim, Kyu-Seok
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.26 no.4
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    • pp.60-69
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    • 2013
  • Objective : This case series study was designed to assess the effect of Gamisungmagalguntang for chronic urticaria identified as "Wind-Heat" pattern by retrospective methods. Methods : We treated 19 patients for chronic urticaria with Gamisungmagalguntang(加味升麻葛根湯), who visited to care chronic urticaria at the department of Ophthalmology, Otolaryngology and Dermatology of Korean Medicine at Kyunghee University Korean Medical Center from 1st January 2013 to 31st August 2013. We analyzed information and body conditions of 19 patients. And by using Urticaria Activicy Score(UAS), frequency and number of wheals, itch severity and total score on a 4-point(0-3) scale were assessed in 19 patients. The change of each criterion and total scores between baseline and follow up were analyzed using paired t-test and Wilcoxon test(p<0.05). Results : 1. UAS improvement was statistically significant(p<0.001). Effects of symptom improvement were excellent(31.58%) that means symptom remission and good(42.10%) that means symptom improved over 50%. 2. Heat sensitivity as suspected provocation factor could be a marker for the Wind-Heat pattern urticaria. 3. Among the Wind-Heat pattern urticaria patients, normal digestion(52.63%) and no thirst(78.95%) were higher than abnormal conditions. Whereas about sweat item, abnormal conditions(57.89%) were higher than normal. That means abnormal sweat conditions could be a marker for a defense qi(衛氣) dysfunction of the Wind-Heat pattern urticaria. Conclusions : Our findings suggest that Gamisungmagalguntang could be effective on the Wind-Heat pattern urticaria.

An Optimum Design of the Shaped Cassegrainian Antenna (수정 곡면 카세그레인 안테나의 최적 설계)

  • Ryu, Hwang;Kim, Ik-Sang
    • The Journal of Engineering Research
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    • v.2 no.1
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    • pp.113-123
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    • 1997
  • The purpose of this paper is an optimum design of the shaped Cassegrainian antenna system for the base station. The process of the shaped Cassegrainian antenna design is as follows : 1) the aperture field distribution is determined so as to meet design specifications, 2) a proper design parameter is selected, 3) extracting of the dimension data for the main and sub-reflector antenna To do these, Hansen's distribution is chosen as the aperture field, and the far-field pattern from the aperture is predicted by the angular spectrum. Firstly, the aperture field distribution is designed to satisfy the specification for design frequency, it is confirmed if this distribution meet the specification for another frequency band. The main- and the sub-reflectors are synthesized so as for the given beamwaveguide feed pattern to be transformed into the prescribed aperture distribution. The designed system has circular aperture, left-right symmetry and no tilted structure. The continuous surface functions of reflectors are obtained by adopting the global interpolation technique to the discrete reflector profiles. Jacobi polynomial-sinusoidal is used as the basis function. A Ka-band Cassegrainian antenna operates over 17.7 – 20.2 GHz for down-link band and 27.5 – 30 GHz for up-link band is designed.

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A Study on the Transport-related Impacts of Flexible Working Policy using Activity-Based Model (활동기반모형을 이용한 유연근무제의 교통부문 영향 연구)

  • CHO, Sung-Jin;BELLEMANS, Tom;JOH, Chang-Hyeon;CHOI, Keechoo
    • Journal of Korean Society of Transportation
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    • v.35 no.6
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    • pp.511-524
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    • 2017
  • This study aims to evaluate the availability of ABM (Active-Based Model), FEATHERS, as a policy evaluation tool. To achieve the goal, scenario analysis on flexible working policy was conducted to measure its impact on activity-travel behavior. As a consequence, there seems no significant change in worker's daily life, other than mitigating traffic congestion due to decreasing commuting travel in the rush hour. The result of VKT (vehicle kilometers traveled) shows an opposite pattern according to given household/individual constraints. The scenario analysis on telecommuting indicates a decreasing trend in both travel frequency and distance because of the diminished number of commuting trips. As the activity space of telecommuters is shifted to a residential area, there are more short-distance trips by using non-motorized transport, which leads to decrease in VKT (using a private vehicle). Thus, the sensitivity of VKT by population groups varies due to transport mode shift (between personal and another mode) and growing non-work trips (using a private mode). This study found few things. First, it is necessary to evaluate the details of policy impact by population groups since it can be varied depending on household/individual characteristics. Second, the case study shows a promising performance of ABM as policy measurement that provides reality in policy evaluation. Third, ABM allows us to do more accurate analysis (i.e. time-series analysis by population groups) of policy assessment than those of FSM (Four-Step Model). Lastly, a further effort in data collection, literature review, and expert survey should be made to enhance the accuracy and confidence of future research.

Study on antioxidative, antidiabetic and antiobesity activity of solvent fractions of smilax china L. leaf extract (청미래덩굴잎 추출물 용매분획의 항산화, 항당뇨 및 항비만 활성연구)

  • Kang, Yun Hwan;Lee, Young-Sil;Kim, Kyoung Kon;Kim, Dae Jung;Kim, Tae Woo;Choe, Myeon
    • Journal of Nutrition and Health
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    • v.46 no.5
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    • pp.401-409
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    • 2013
  • Smilax china L., a native plant found in Asian countries, has several medicinal properties including antioxidant, anti-inflammatory, and anti-cancer effects. Although the root of the plant is commonly used as traditional herbal medicine in Korea and China, the medicinal properties of the leaves have not gained the same attention. In this study, we analyzed the antioxidant activity, ${\alpha}$-glucosidase inhibitory effect and lipid accumulation inhibition effect of Smilax china L. leaf water extract (SCLE) and its solvent fractions. SCLE was fractionated by using a series of organic solvents, including ethylacetate (EA) and n-butanol (BuOH). The EA fraction had the highest total polyphenol content ($440.20{\pm}12.67$ mg GAE/g) and total flavonoid content ($215.14{\pm}24.83$ mg QE/g). The radical scavenging activity $IC_{50}$ values of the EA fraction for 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2-azino-bis-(3-ethylbenzthiazoline)-6-sulfonic acid (ABTS) were 0.022 mg/mL and 0.13 mg/mL, respectively. Further, SOD-like activity and reducing power values of the EA fraction were higher than those of the other fractions. However, both the ${\alpha}$-glucosidase and lipid accumulation inhibition assays showed that the BuOH fraction ($83.35{\pm}4.18%$ at 1 mg/mL) and water extract ($11.27{\pm}2.67%$) were more effective than the EA fraction ($64.13{\pm}6.35%$, and $45.66{\pm}7.20%$). These results provide new insights into the potential anti-diabetic and anti-obesity effects of Smilax china L. leaf.

Extraction of the ship movement information by a radar target extractor (Radar Target Extractor에 의한 선박운동정보의 추출에 관한 연구)

  • Lee, Dae-Jae;Kim, Kwang-Sik;Byun, Duck-Soo
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.38 no.3
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    • pp.249-255
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    • 2002
  • This paper describes on the extraction of ship's real-time movement information using a combination full-function ARPA radar and ECS system that displays radar images and an electronic chart together on a single PC screen. The radar target extractor(RTX) board, developed by Marine Electronics Corporation of Korea, receives radar video, trigger, antenna bearing pulse and heading pulse signals from a radar unit and processes these signals to extract target information. The target data extracted from each pulse repetition interval in DSPs of RTX that installed in 16 bit ISA slot of a IBM PC compatible computer is formatted into a series of radar target messages. These messages are then transmitted to the host PC and displayed on a single screen. The position data of target in range and azimuth direction are stored and used for determining the center of the distributed target by arithmetic averaging after the detection of the target end. In this system, the electronic chart or radar screens can be displayed separately or simulaneously and in radar mode all information of radar targets can be recorded and replayed In spite of a PC based radar system, all essential information required for safe and efficient navigation of ship can be provided.

Herbicidal Activity of Natural Compound Chrysophanic Acid Under the Greenhouse Condition (온실조건에서 천연물질 Chrysophanic Acid의 제초활성)

  • Kang, Chung-Kil;Lee, Sang-Beom;Lee, Byung-Mo;Nam, Hong-Sik;Lee, Yong-Ki;Jee, Hyeong-Jin;Hong, Moo-Ki;Rho, Yeong-Deok;Choi, Jung-Sup
    • Korean Journal of Weed Science
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    • v.31 no.1
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    • pp.112-117
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    • 2011
  • A series of experiments was conducted to investigate the herbicidal activity of natural compound chrysophanic acid under the greenhouse condition in 16 weed species. Chrysophanic acid showed non-selective herbicidal activity. While chrysophanic acid exhibited severe injury by foliar treatment, little or no injury was found by the soil treatment. Among the tested weeds, the most effective activity was found in grass and broad leaf weeds, a lower significant difference in herbicidal activity was found in sedge. At early post-emergence, weeds appeared to be very susceptible to chrysophanic acid with $2,000{\mu}g\;mL^{-1}$. The higher the natural compound concentrations, the lower weed growth. At middle post-emergence, weeds appeared to be very effective to chrysophanic acid with $30,000{\mu}g\;mL^{-1}$.

The Factor Analysis of Land Surface Temperature(LST) Change using MODIS Imagery and Panel Data (MODIS 영상 자료와 패널 자료를 이용한 지표면온도변화 요인분석)

  • BAE, Da-Hye;KIM, Hong-Myung;HA, Sung-Ryong
    • Journal of the Korean Association of Geographic Information Studies
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    • v.21 no.1
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    • pp.46-56
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    • 2018
  • This paper aimed to identify main factors of community characters, which have an effect on the land surface temperature(LST) change and estimate the impacting coefficient(ratio) of factors in a significant level of statistics. Chungcheongbuk-do province was selected and then partitioned into city and county areas for the sake of convenience of modeling. LST time series data and the community character data were developed based on Terra Satellite MODIS data and collected from the National Statistical Office, respectively. By the cause and effect relationship between community characters and LST, regression coefficients were estimated using a penal model. In a panel modeling, LST and community characters were used as a dependent variable and explanatory variables, respectively. Panel modeling analysis was carried out using statistical package STATA14 and one-way fixed effect model was selected as the most suitable model to evaluate the regression coefficients in the study area. The impacting ratio of LST change by any explanatory variable derived from the regression coefficients of the panel model fixed. Impacting ratios for industrial areas, elevation ${\times}$ building, energy usage, average window speed, non-urban management area, agricultural, nature and environmental conservation, average precipitation were 3.746, 2.856, 2.742, 0.553, 0.102, 0.071 and 0.003, respectively.

Wideband Colpitts Voltage Controlled Oscillator with Nanosecond Startup Time and 28 % Tuning Bandwidth for Bubble-Type Motion Detector (나노초의 발진 기동 시간과 28 %의 튜닝 대역폭을 가지는 버블형 동작감지기용 광대역 콜피츠 전압제어발진기)

  • Shin, Im-Hyu;Kim, Dong-Wook
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.24 no.11
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    • pp.1104-1112
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    • 2013
  • This paper presents a wideband Colpitts voltage controlled oscillator(VCO) with nanosecond startup time and a center frequency of 8.35 GHz for a new bubble-type motion detector that has a bubble-layer detection zone at the specific distance from itself. The VCO circuit consists of two parts; one is a negative resistance part with a HEMT device and Colpitts feedback structure and the other is a resonator part with a varactor diode and shorted shunt microstrip line. The shorted shunt microstrip line and series capacitor are utilized to compensate for the input reactance of the packaged HEMT that changes from capacitive values to inductive values at 8.1 GHz due to parasitic package inductance. By tuning the feedback capacitors which determine negative resistance values, this paper also investigates startup time improvement with the negative resistance variation and tuning bandwidth improvement with the reactance slope variation of the negative resistance part. The VCO measurement shows the tuning bandwidth of 2.3 GHz(28 %), the output power of 4.1~7.5 dBm and the startup time of less than 2 nsec.

FOLLOW-UP OBSERVATIONS TOWARD PLANCK COLD CLUMPS WITH GROUND-BASED RADIO TELESCOPES

  • LIU, TIE;WU, YUEFANG;MARDONES, DIEGO;KIM, KEE-TAE;MENTEN, KARL M.;TATEMATSU, KEN;CUNNINGHAM, MARIA;JUVELA, MIKA;ZHANG, QIZHOU;GOLDSMITH, PAUL F;LIU, SHENG-YUAN;ZHANG, HUA-WEI;MENG, FANYI;LI, DI;LO, NADIA;GUAN, XIN;YUAN, JINGHUA;BELLOCHE, ARNAUD;HENKEL, CHRISTIAN;WYROWSKI, FRIEDRICH;GARAY, GUIDO;RISTORCELLI, ISABELLE;LEE, JEONG-EUN;WANG, KE;BRONFMAN, LEONARDO;TOTH, L. VIKTOR;SCHNEE, SCOTT;QIN, SHENGLI;AKHTER, SHAILA
    • Publications of The Korean Astronomical Society
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    • v.30 no.2
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    • pp.79-82
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    • 2015
  • The physical and chemical properties of prestellar cores, especially massive ones, are still far from being well understood due to the lack of a large sample. The low dust temperature (< 14 K) of Planck cold clumps makes them promising candidates for prestellar objects or for sources at the very initial stages of protostellar collapse. We have been conducting a series of observations toward Planck cold clumps (PCCs) with ground-based radio telescopes. In general, when compared with other star forming samples (e.g. infrared dark clouds), PCCs are more quiescent, suggesting that most of them may be in the earliest phase of star formation. However, some PCCs are associated with protostars and molecular outflows, indicating that not all PCCs are in a prestellar phase. We have identified hundreds of starless dense clumps from a mapping survey with the Purple Mountain Observatory (PMO) 13.7-m telescope. Follow-up observations suggest that these dense clumps are ideal targets to search for prestellar objects.

Full-Length Enriched cDNA Library Construction from Tissues Related to Energy Metabolism in Pigs

  • Lee, Kyung-Tai;Byun, Mi-Jeong;Lim, Dajeong;Kang, Kyung-Soo;Kim, Nam-Soon;Oh, Jung-Hwa;Chung, Chung-Soo;Park, Hae-Suk;Shin, Younhee;Kim, Tae-Hun
    • Molecules and Cells
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    • v.28 no.6
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    • pp.529-536
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    • 2009
  • Genome sequencing of the pig is being accelerated because of its importance as an evolutionary and biomedical model animal as well as a major livestock animal. However, information on expressed porcine genes is insufficient to allow annotation and use of the genomic information. A series of expressed sequence tags of 5' ends of five full-length enriched cDNA libraries (SUSFLECKs) were functionally characterized. SUSFLECKs were constructed from porcine abdominal fat, induced fat cells, loin muscle, liver, and pituitary gland, and were composed of non-normalized and normalized libraries. A total of 55,658 ESTs that were sequenced once from the 5′ ends of clones were produced and assembled into 17,684 unique sequences with 7,736 contigs and 9,948 singletons. In Gene Ontology analysis, two significant biological process leaf nodes were found: gluconeogenesis and translation elongation. In functional domain analysis based on the Pfam database, the beta transducin repeat domain of WD40 protein was the most frequently occurring domain. Twelve genes, including SLC25A6, EEF1G, EEF1A1, COX1, ACTA1, SLA, and ANXA2, were significantly more abundant in fat tissues than in loin muscle, liver, and pituitary gland in the SUSFLECKs. These characteristics of SUSFLECKs determined by EST analysis can provide important insight to discover the functional pathways in gene networks and to expand our understanding of energy metabolism in the pig.