• Title/Summary/Keyword: center loss

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Effect of Exopolymers of Aureobasidium pullulans on Improving Osteoporosis Induced in Ovariectomized Mice

  • SONG HEBOK;PARK DONG CHAN;DO GYUNG MIN;HWANG SEUNG-LARK;LEE WON KYU;KANG HEUN-SOO;PARK BOK-RYUN;JANG HEE-JEONG;SONG CHANG-WOO;PARK EUI KYUN;KIM SHIN-YOON;HUH TAE-LIN
    • Journal of Microbiology and Biotechnology
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    • v.16 no.1
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    • pp.37-45
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    • 2006
  • Treatment with exopolymers of Aureobasidium pullulans SM-2001 containing $\beta-1,3/1,6-glucan$ inhibited osteoclastogenesis of bone marrow stem cells in a co-culture system with calvariae osteoblastic cells. In addition, the treatment increased mineral deposition in osteoblastic cells. These two observations prompted us to evaluate whether the exopolymers could be used as an anti-osteoporotic agent, and efficacy of the exopolymers to prevent bone loss was compared with alendronate, a bisphosphonate, in ovariectomized mice prone to osteoporosis. Administration of the exopolymers to the ovariectomized mice resulted in improved effects on femur weight and histomorphometric changes of femur such as trabecular bone volume (TBV), trabecular bone thickness (TBT), and cortical bone thickness (CBT). In conclusion, the exopolymers treatment inhibited bone loss from osteoporosis induced by ovariectomy, and the effect was comparable to alendronate administration.

Classification of Organs Using Impedance of Ultrasonic Surgical Knife to improve Surgical Efficiency (초음파 수술기의 수술 효율성 향상을 위한 진동자 임피던스 측정에 따른 조직 분류 연구)

  • Kim, Hong Rae;Kim, Sung Chun;Kim, Kwang Gi;Kim, Young-Woo
    • Journal of Biomedical Engineering Research
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    • v.34 no.3
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    • pp.141-147
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    • 2013
  • Ultrasonic shears is currently in wide use as an energy device for minimal invasive surgery. There is an advantage of minimizing the carbonization behavior of the tissue due to the vibrational energy transfer system of the transducer by applying a piezoelectric ceramic. However, the vibrational energy transfer system has a pitfall in energy consumption. When the movement of the forceps is interrupted by the tissue, the horn which transfers the vibrational energy of the transducer will be affected. A study was performed to recognize different tissues by measuring the impedance of the transducer of the ultrasonic shears in order to find the factor of energy consumption according to the tissue. In the first stage of the study, the voltage and current of the transducer connecting portion were measured, along with the phase changes. Subsequently, in the second stage, the impedance of the transducer was directly measured. In the final stage, using the handpiece, we grasped the tissue and observed the impedance differences appeared in the transducer To verify the proposed tissue distinguishing method, we used the handpiece to apply a force between 5N and 10N to pork while increasing the value of the impedance of the transducer from 400 ${\Omega}$.. It was found that fat and skin tissue, tendon, liver and protein all have different impedance values of 420 ${\Omega}$, 490 ${\Omega}$, 530 ${\Omega}$, and 580 ${\Omega}$, respectively. Thus, the impedance value can be used to distinguish the type of tissues grasped by the forceps. In the future study, this relationship will be used to improve the energy efficiency of ultrasonic shears.

Development of Primary Standard Gas Mixtures of Fourteen Volatile Organic Compounds in Hazardous Air Pollutants for Accurate Ambient Measurements in Korea (at 1 μmol/mol Levels) (유해대기오염물질 중 14종의 휘발성유기화합물 1차 표준가스개발 (1 μmol/mol 수준))

  • Kang, Ji Hwan;Kim, Young Doo;Kim, Mi Eon;Lee, Jinhong;Lee, Sangil
    • Journal of Korean Society for Atmospheric Environment
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    • v.34 no.2
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    • pp.331-341
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    • 2018
  • Hazardous air pollutants(HAPs) in the atmosphere are regulated as major air pollutants in Korea by the Air Pollution Control Act. In order to manage and control HAPs, accurate standards, which are traceable to the International System of Units(SI), are required. In this study, primary standard gas mixtures(PSMs) of volatile organic compounds(VOCs) which are specified as HAPs were developed at $1{\mu}mol/mol$ levels. The selected fourteen VOCs include Benzene, Toluene, Ethylbenzene, m-Xylene, Styrene, o-Xylene, Chloroform, 1,1,2-Trichloroethane, Trichloroethylene, Tetrachloroethylene, 1,1-Dichloroethane, Carbon tetrachloride, 1,3-Butadiene, and Dichloromethane. The HAPs PSMs were gravimetrically prepared in aluminum cylinders and their consistency was verified within the relative expanded uncertainty of 0.71% (k=2). Potential adsorption loss onto the internal surface of cylinders was estimated by cylinder-to-cylinder division method. No adsorption loss was observed within the uncerainty of 0.53%. The long-term stability of the HAPs PSMs was evaluated comparing with freshly prepared HAPs PSMs. The HAPs PSMs were stable for one year within the uncertainty of 0.38%. The final uncertainty of the PSMs was determined by combining the preparation uncertainty, verification uncertainty, and stability uncertainty. Finally, traceable and stable HAPs PSMs at $1{\mu}mol/mol$ levels were developed with the uncertainty of less than 0.76% in high-pressure aluminum cylinders.

Features of Patients Associated with Falls from Heights Admitted to Republican Research Center of Emergency Medicine (우즈베키스탄 국립응급병원에 내원한 낙상환자들의 임상적인 특성)

  • Khadjibaev, Abdukhakim Muminovich;Sultanov, Pulat Karimovich;Kim, Hoon
    • Journal of Trauma and Injury
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    • v.28 no.4
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    • pp.248-255
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    • 2015
  • Purpose: study of the mutual influence of the individual anatomical regions damage in patients associated with falls from heights. Methods: 561 medical reports of patients associated with falls from heights admitted to Republican Research Center of Emergency Medicine (RRCEM), in period of 2010-2013 yy, were analyzed retrospectively. Patient's age range was from 15 to 89. Treatment of these patients held in three stages: period of acute disorders of vital functions; relative stabilization period; stabilization of vital functions. The scope and content of medical diagnostic procedures performed on pre-hospital and intensive care stages. The severity of each injury was scored according to the AIS scale, the total severity of lesions was scored by points due to ISS. Digital material is treated by methods of mathematical statistics. Results: Falls from heights leads to associated injuries for 4 times more than isolated trauma, and increases according to height of fall and falling surface. Patients with TBI+chest trauma, are most serious contingent that has highest mortality and complications (36.8%). TBI+musculoskeletal system trauma are characterized by high blood loss, traumatic shock and fat embolism, forming a vicious circle. Conclusion: in patients associated with falls from heights clinical manifestations of injuries mutual aggravation syndrome will be seen. TBI leads to complication of chest trauma, delayed diagnostics of abdominal and chest trauma, aggravation of coma condition. Developing of high blood loss and fat embolism in musculoskeletal system trauma leads to shock and pulmonary embolism, which increases probability of death in the presence of abdominal or chest trauma, but abdominal trauma or chest trauma has no significant effect on the severity of the musculoskeletal system trauma.

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Performance of a 5 L Liquid Hydrogen Storage Vessel (5 L급 액체수소 저장용기의 성능특성 연구)

  • KARNG, SARNG WOO;GARCEAU, NATHANIEL;LIM, CHANG MU;BAIK, JONG HOON;KIM, SEO YOUNG;OH, IN-HWAN
    • Journal of Hydrogen and New Energy
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    • v.26 no.3
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    • pp.234-240
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    • 2015
  • In the face of the world's growing energy storage needs, liquid hydrogen offers a high energy density solution for the storage and transport of energy throughout society. A 5 L liquid hydrogen storage tank has been designed, fabricated and tested to investigate boil-off rate of liquid hydrogen. As the insulation plays a key role on the cryogenic vessels, various insulation methods have been employed. To reduce heat conduction loss, the epoxy resin-based insulation supports G-10 were used. To minimize radiation heat loss, vapor cooled radiation shield, multi-layer insulation, and high vacuum were adopted. Mass flow meter was used to measure boil-off rate of the 5 L cryogenic vessel. A series of performance tests were done for liquid nitrogen and liquid hydrogen to compare with design parameters, resulting in the boil-off rate of 1.7%/day for liquid nitrogen and 16.8%/day for liquid hydrogen at maximum.

Development of the HPM System to Improve Efficiency of the Hydraulic Excavator (유압식 굴삭기 효율 향상을 위한 HPM 시스템 개발)

  • Kwon, Yong Cheol;Lee, Kyung Sub;Kim, Sung Hun;Koo, Byoung Kook
    • Journal of Drive and Control
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    • v.16 no.4
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    • pp.1-8
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    • 2019
  • The HPM (High-speed Power Matching) system is an electro-hydraulic control system. It directly controls the swash plate of the pump by selecting four-loop logic based on joystick signals, pump flow, and pressure signal to improve the efficiency and controllability of construction machines. In the NFC (Negative Flow Control) system, a typical pump control system using conventional open center type MCV, the loss is continuously generated by flow through the center bypass line even when the excavator is not in operation. Also, due to the slow response of the pump that indirectly controls the flow rate using the pressure regulator, peak pressure occurs at the start or stop of the operation. Conversely, the HPM system uses an MCV without center-by-pass flow path and the swash plate of a pump for the HPM is controlled by a high-speed proportional flow control valve. As a result, the HPM system minimizes energy loss in standby state of the excavator and enables peak pressure control through rapid electro-hydraulic control of a pump. In this paper, the concept of the HPM system algorithm is introduced and the hydraulic system efficiency is compared with the NFC system using the excavator SAT (System Analysis Tool).

Construction of Deletion Map of 16q by LOH Analysis from HCC Patients and Physical Map on 16q 23.3 - 24.1 Region

  • Chung, Jiyeol;Choi, Nae Yun;Shim, Myoung Sup;Choi, Dong Wook;Kang, Hyen Sam;Kim, Chang Min;Kim, Ung Jin;Park, Sun Hwa;Kim, Hyeon;Lee, Byeong Jae
    • Genomics & Informatics
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    • v.1 no.2
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    • pp.101-107
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    • 2003
  • Loss of heterozygosity (LOH) has been used to detect deleted regions of a specific chromosome in cancer cells. LOH on chromosome 16q has been reported to occur frequently in progressed hepatocellular carcinoma (HCC). Liver tissues from 37 Korean HCC patients were analyzed for LOH by using 25 polymorphic microsatellite markers distributed along 16q. Out of the 37 HCC patients studied, 21 patients (56.8%) showed LOH in various regions of 16q with at least one polymorphic marker. Puring the analysis of these 21 LOH cases, 6 patients showed interstitial LOHs in which the boundary of the LOH region was defined. With two rounds of LOH analysis, five commonly occurring interstitial LOH regions were identified; 16q21-22.1, 16q22.2 - 22.3, 16q22.3, 16q23.2 and 16q23.3 - 24.1. Among the five LOH regions the 16q23.3 - 24.1 region has been reported to be related with chromosome instability. A complete physical map, which covers the 3.2 Mb region of 16q23.3 - 24.1 (D16S402 and D16S486), was constructed to identify novel candidate tumor suppressor genes. We provide the minimally tiling path map consisting of 28 BAC clones. There was one gap between NT_10422.11 and NT_019609.9 of the human genome sequence contig (NCBI sequence build 33, April 29, 2003). This gap can be filled by sequencing the R-1425M20 clone which bridges these sequence contigs.

Design of the Wide-Band Printed-Monopole Antenna Using Parasitic Elements (기생 소자를 이용한 광대역 프린트 모노폴 안테나의 설계)

  • Seo, Seung-Up;Lee, Yun-Bok;Yang, Myo-Geun;Seong, Won-Mo
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.19 no.7
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    • pp.719-725
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    • 2008
  • In this paper, we have proposed a printed monopole antenna using parasitic elements. The broadband characteristics of the antenna is obtained by using the printed monopole and parasitic elements. To confirm the broadband characteristics of the antenna, of have designed and fabricated the proposed antenna. The return loss and radiation patterns are measured in the frequency range of$0.8{\sim}1.2\;GHz$. The measured results show that the proposed antenna has return loss less than -10 dB in the operating frequency band and the radiation pattern is the dipole-like patterns. The antenna gain varies from 1.7 to 4.6 dBi in the operating frequency band. Thus, the proposed antenna can be used for the broadband repeater antenna $0.806{\sim}0.960\;GHz$(TRS-800, CDMA and GSM-900).

An Efficient Intra Prediction Mode Decision for Spatial Enhancement Layer (공간 향상 계층에서 효율적인 화면 내 예측 모드 선택 방법)

  • Myung, Jin-Su;Park, Sung-Jae;Oh, Seoung-Jun;Sim, Dong-Gyu;Kim, Byung-Gyu
    • Journal of Broadcast Engineering
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    • v.12 no.5
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    • pp.491-502
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    • 2007
  • In this parer, we propose an efficient intra prediction mode decision scheme in Scalable Video Coding(SVC) which is an emerging video coding standard as an extension of H.264/MPEG-4 AVC(Advanced Video Coding). The proposed method in base on the characteristic of macroblock smoothness follows the statistical analysis of intra prediction mode in an enhancement layer and it decides a candidate intra prediction mode. We also propose an early termination scheme for Intra_BL mode decision where the RD cost value of Intra_BL is utilized. Simulation results show that the proposed method reduces 54.67% of the computation complexity of intra prediction coding, while the degradation in video quality is negligible; for low QP values, the average PSNR loss is very negligible, equivalently the bit rate increases by 0.011%. For high QP values, the average PSNR loss is less than 0.01dB, which equals to 0.249% increase in bitrate.

A Sketch-based 3D Object Retrieval Approach for Augmented Reality Models Using Deep Learning

  • Ji, Myunggeun;Chun, Junchul
    • Journal of Internet Computing and Services
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    • v.21 no.1
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    • pp.33-43
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    • 2020
  • Retrieving a 3D model from a 3D database and augmenting the retrieved model in the Augmented Reality system simultaneously became an issue in developing the plausible AR environments in a convenient fashion. It is considered that the sketch-based 3D object retrieval is an intuitive way for searching 3D objects based on human-drawn sketches as query. In this paper, we propose a novel deep learning based approach of retrieving a sketch-based 3D object as for an Augmented Reality Model. For this work, we introduce a new method which uses Sketch CNN, Wasserstein CNN and Wasserstein center loss for retrieving a sketch-based 3D object. Especially, Wasserstein center loss is used for learning the center of each object category and reducing the Wasserstein distance between center and features of the same category. The proposed 3D object retrieval and augmentation consist of three major steps as follows. Firstly, Wasserstein CNN extracts 2D images taken from various directions of 3D object using CNN, and extracts features of 3D data by computing the Wasserstein barycenters of features of each image. Secondly, the features of the sketch are extracted using a separate Sketch CNN. Finally, we adopt sketch-based object matching method to localize the natural marker of the images to register a 3D virtual object in AR system. Using the detected marker, the retrieved 3D virtual object is augmented in AR system automatically. By the experiments, we prove that the proposed method is efficiency for retrieving and augmenting objects.