• Journal of Ginseng Research
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• v.44 no.6
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• pp.833-842
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• 2020

Background: Ulcerative colitis (UC) is a commonly encountered large intestine disease in the contemporary world that terminates into colorectal cancer; therefore, the timely treatment of UC is of major concern. Panax ginseng Meyer is an extensively consumed herbal commodity in South East Asian countries, especially Korea. It exhibits a wide range of biologically beneficial qualities for almost head-to-toe ailments in the body. Epimedium koreanum Nakai (EKN) is also a widely used traditional Korean herbal medicine used for treating infertility, rheumatism, and cardiovascular diseases. Materials and methods: Separately the anti-inflammatory activities of both red ginseng extracts (RGEs) and EKNs had been demonstrated in the past in various inflammatory models; however, we sought to unravel the anti-inflammatory activities of the combination of these two extracts in dextran sulfate sodium (DSS)-induced ulcerative colitis in mice model because the allopathic remedies for UC involve more side effects than benefits. Results: Our results have shown that the combination of RGE + EKN synergistically alleviated the macroscopic lesions in DSS-induced colitic mice such as colon shortening, hematochezia, and weight loss. Moreover, it restored the histopathological lesions in mice and decreased the levels of proinflammatory mediators and cytokines through the repression of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) and nucleotide-binding domain (NOD)-like receptor protein 3 (NLRP-3) expression. In vitro, this combination also reduced the magnitude of nitric acid (NO), proinflammatory mediators and cytokine through NF-κB and mitogen-activated protein kinase (MAPK) pathways in RAW 264.7 mouse macrophage cells. Conclusion: In the light of these findings, we can endorse this combination extract as a functional food for the prophylactic as well as therapeutic treatment of UC in humans together with allopathic remedies.

• Journal of the Society of Naval Architects of Korea
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• v.41 no.6
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• pp.120-125
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• 2004

There are very few numbers of 115K FPP (Fixed Pitch Propulsion) Tankers for the Baltic ice class IA because the minimum power requirement of FMA (Finish- Swedish Maritime Association) needs quite large engine power and the 40 m Beam is out of calculation range of FMA minimum power requirements. The shipyard has no choice except to increase the engine power to satisfy FMA minimum power requirement Rule. And the operation cost, efficiency of hullform and its building cost are not good from the ship owners' point of view To solve this problem, the experience of ice breaking tanker development and the ice tank test results were adopted. The main idea to reduce the ice resistance is by reducing waterline angle at design load waterline. The reason behind the main idea is to reduce the ice-clearing force. Two hull forms were developed to satisfy Baltic Ice class IA. Two ice tank tests and one towing tank test was performed at MARC (Kvaener-Masa Arctic Research Center) and SSMB (Samsung Ship Model Basin) facilities, respectively. The purpose of these tests was to verify the performance in ice and open water respectively The hull form 2 shows less speed loss compared to Hull form 1 in open water operation but hull form 2 shows very good ice clearing ability. finally the Hull Form 2 satisfying Baltic ice class IA. The merit of this hull form is to use the same engine capacity and no major design changes in hull form and other related designs But the hull structure has to be changed according to the ice class grade. The difference in two hull form development methods, ice model test methods and analysis methods of ice model test will be described in this paper.

• Korean Journal of Soil Science and Fertilizer
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• v.45 no.5
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• pp.711-716
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• 2012

Due to the climate change in South Korea the annual total precipitation will increase by 17 percent by 2100. Rainfall is concentrated during the summer in South Korea and the landslide of farmland by heavy rain is expected to increase. Because regional torrential rains accompanied by a storm continue to cause the damage in farmland urgent establishment of adaptation plant for minimizing the damage is in need. In this study we assessed vulnerability of landslide of farmland by heavy rain for local governments. Temporal resolution is 2000 year and the future 2020 year, 2050 year, 2100 year via A1B scenario. Vulnerability of local government were evaluated by three indices such as climate exposure, sensitivity, adaptive capacity and each index is calculated by selected alternative variable. Collected data was normalized and then multiplied by weight value that was elicited in delphi investigation. Current vulnerability is concentrated in Jeju island and Gyeongsangnam-do, however, it is postulated that Kangwon-do will be vulnerable in the future. Through this study, local governments can use the data to establish adaptation plans for farmland landslide by climate change.

• Journal of Korean Society of Transportation
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• v.24 no.7 s.93
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• pp.101-114
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• 2006

Recently due to the increase of cars and city life, the traffic congestion has worsened. It Is particularly worse in the center of the metropolis. Within the general public means, the public transport buses have the advantage of being more cheap, accessible and mobile. But as there is no separate lane for buses, the collision of cars and buses are creating damage to public service. In order to solve this situation, the bus priority signal system has been introduced to reduce the bus travel time and improve its services. The purpose of this study is to establish bus priority signal algorithm which builds bus efficiency under the real-time traffic signal control system and to analyze the effect of it. As the green time was calculated against real time (under the real-time traffic signal control system), compared to existing bus priority signal there was a reduction in cross street loss. The modified cycle was used to maintain signal progression. A case study was carried out using VISSIM simulation model. In result of this study, we found that there was a decrease in bus travel time despite some evidence of car delays and compared to existing bus priority signal the delay of dishonor could be reduced dramatically. The analysed result of person delay using MOE, is that there is evidence that when bus priority signal is in effect, the person delay is reduced.

• Journal of the Korean Society of Marine Environment & Safety
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• v.26 no.4
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• pp.392-402
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• 2020

We investigated the concentrations of acid volatile sulfide (AVS), ignition loss (IL), total organic carbon (TOC), total nitrogen (TN), and metallic elements (As, Cd, Cr, Cu, Fe, Hg, Mn, Pb, and Zn), in August 2015, to determine the spatial distribution and pollution status of organic matter and metals in the surface sediment of Jinju Bay, a spraying shellfish farming area, Korea. The concentrations of organic matter and metallic elements were significantly higher in the southern part of the bay than in the mouth and center of the bay. The C/N ratio (5.7~8.0) in the sediment represents the dominance of organic matter of oceanic origin in the surface sediment of the study area. The concentrations of AVS, TOC, and metals (As, Cd, Cr, Cu, Hg, Pb, and Zn) were much lower than the values of the sediment quality guidelines applied in Korea. Based on the results of the pollution load index (PLI) and ecological risk index (ERI), the metal concentrations in the surface sediment of Jinju Bay have a weakly negative ecological effect on benthic organisms although the sediments with high metal pollution status are distributed in the southern parts of the bay, with high dense shellfish farming areas. Thus, the surface sediments in Jinju Bay are not polluted with organic matter and are slightly polluted with metallic elements.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.41
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• pp.43.1-43.5
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• 2019

Background: Reconstructive surgery is often required for tumors of the oral and maxillofacial region, irrespective of whether they are benign or malignant, the area involved, and the tumor size. Recently, three-dimensional (3D) models are increasingly used in reconstructive surgery. However, these models have rarely been adapted for the fabrication of custom-made reconstruction materials. In this report, we present a case of maxillary reconstruction using a laboratory-engineered, custom-made mesh plate from a 3D model. Case presentation: The patient was a 56-year-old female, who had undergone maxillary resection in 2011 for intraoral squamous cell carcinoma that presented as a swelling of the anterior maxillary gingiva. Five years later, there was no recurrence of the malignant tumor and a maxillary reconstruction was planned. Computed tomography (CT) revealed a large bony defect in the dental-alveolar area of the anterior maxilla. Using the CT data, a 3D model of the maxilla was prepared, and the site of reconstruction determined. A custom-made mesh plate was fabricated using the 3D model (Okada Medical Supply, Tokyo, Japan). We performed the reconstruction using the custom-made titanium mesh plate and the particulate cancellous bone and marrow graft from her iliac bone. We employed the tunneling flap technique without alveolar crest incision, to prevent surgical wound dehiscence, mesh exposure, and alveolar bone loss. Ten months later, three dental implants were inserted in the graft. Before the final crown setting, we performed a gingivoplasty with palate mucosal graft. The patient has expressed total satisfaction with both the functional and esthetic outcomes of the procedure. Conclusion: We have successfully performed a maxillary and dental reconstruction using a custom-made, pre-bent titanium mesh plate.

• Journal of Korean Academy of Nursing Administration
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• v.4 no.1
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• pp.73-88
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• 1998

The management of nursing resource is very important. that is because nursing staff accounts for 30-40% of total staff in a hospital and nurses provide patoents with attentive service for hours daily. The continuous turnover of nursing staff. however, impedes the quality-oriented nursing care, which will consequently leads to the loss of human and material resource in competitive society. This study aimed to calculate nurse's activity and compare the activity amount based on career experience. Futhermore it aimed to find factors which would influence 'quality weighed direct nursing activity amount'. Questionnaires and check lists for this study were distributed to nurses in a suburban hospital outside of Seoul from October 20 to November 14. 1997. The nursing activities were calculated according to professionality. independency and working hour. And then it were accumulated by quality score. The collected data was analyzed by statistical methods as t-test, ANOVA, correlation, multiple regression. The results of this study were as follows ; Firstly, carrel' experience had no influence on the quality weighed nursing activity amount. But the quality level of service of skilled nurses was higher than that of new nurses. Secondly, career was a variable affecting the quality in nursing service. So career was positively related to the quality of nursing care. Patient's disease severity and number of patient were positively correlated with weighed nursing activity amount. But job satisfaction was negatively correlated v:ith the amount. Thirdly, the independent variables which had significant influence on the weighed nursing activity amount were disease severity and the number of patients, The severity score and number of patient were directly proportional to the weighed nursing activity amount. This results indicated· that weighed nursing activity amount was influenced by the number of patient and patient's disease severity. The quality score of nursing services for experienced members is higher than that of new staff. But both new and skilled staff showed no difference in the quality weighed nursing activity amount. Internal and. external environment influences nursing activities. The quality of nursing services is very important factor in nursing activity. Therefore nursing managers should make an effort to improve nursing care quality through continuous research. Also they should try to maintain experience nurses and assign nursing staff appropriately with patient's severity and other relevant factors being considered. The quality-improved nursing care in the hospital will strengthen hospital's competitiveness.

• The Journal of the Acoustical Society of Korea
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• v.34 no.6
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• pp.411-422
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• 2015

This paper presents an overview of the geological environment investigation and underwater acoustic measurements for the purpose of "Study on the Relationship between the Geological Environment and Acoustic Propagation in Shallow Water", which are jointly carried out by KIOST (Korea Institute of Ocean Science & Technology) and Hanyang University in the western shallow water off the Taean peninsula in the Yellow Sea in April-May 2013. The experimental site was made up of various sediment types and bedforms due to the strong tidal currents and coastal geomorphological characteristics. The geological characteristics of the study area were intensively investigated using multi-beam echo sounder, sub-bottom profiler, sparker system and grab sampler. Acoustic measurements with a wide range of research topics in a frequency range of 20~16,000 Hz: 1) low frequency sound propagation, 2) mid-frequency bottom loss, 3) spatial coherence analysis of ambient noise, and 4) mid- frequency bottom backscattering were performed using low- and mid-frequency sound sources and vertical line array. This paper summarizes the topics that motivated the experiment, methodologies of the acoustic measurements, and acoustic data analysis based on the measured geological characteristics, and describes summary results of the geological, meteorological, and oceanographic conditions found during the experiments.

• Journal of Environmental Science International
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• v.17 no.7
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• pp.755-765
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• 2008

To investigate correlation between the distribution of marine bacteria and environmental characteristics in the surface sediments of Kamak Bay, chemical oxygen demand(COD), acid volatile sulfide(AVS), ignition loss(IL), total organic carbon(TOC), and total organic nitrogen(TON) were measured and analyzed at 7 stations in winter and summer. In winter, COD and AVS ranged from 13.45 mg/g to 30.06 mg/g(average: 23.58 mg/g) and from 0.03 mg/g to 1.04 mg/g(average: 0.63 mg/g), respectively. IL, TOC, and TON ranged from 8.03% to 11.41%(average: 9.41%), from 1.17% to 2.10%(average: 1.62%), and from 0.09% to 0.18%(average 0.15%), respectively. In summer, COD, AVS, IL, TOC, and TON ranged from 14.06 mg/g to 32.19 mg/g(average: 24.71 mg/g), from 0.03 mg/g to 1.11 mg/g(average: 0.66 mg/g), from 9.00% to 12.15%(average: 10.96%), from 1.27% to 2.12%(average 1.77%), and from 0.12% to 0.19%(average: 0.16%), respectively. These values were relatively higher than those in winter. Kamak Bay had high C/N ratio that might be resulted from the input of terrestrial sewage and industrial wastewater. The number of marine viable bacteria was $8.9{\times}10^4\;cfu/g$ in winter and $9.7{\times}10^5\;cfu/g$ in summer. The most abundant species were Pseudomonas spp., Flavobacterium spp., and Vibrio spp, in the surface sediments of Kamak Bay. It was found that the concentration of organic matters and viable bacterial cells in the inner part were relatively higher than those in the outer of Kamak Bay. The distribution of viable bacterial cells was closely influenced by environmental factors.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.26 no.5
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• pp.471-482
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• 2015

In this paper, design and implementation of the 94 GHz Gunn oscillator and the evaluation of the maximum power of the Gunn diode used in the oscillator are presented. The 94 GHz Gunn oscillator is used InP Gunn diode and designed employing a WR-10 waveguide. The designed oscillator is fabricated through machining and its performance is measured. The fabricated oscillator shows an oscillation frequency of 95 GHz, output power of 12.64 dBm, and phase noise of -92.7 dBc/Hz at 1 MHz offset frequency. To evaluation the maximum power of the InP Gunn diode used in oscillator, the oscillator structure is modified to a structure having a diaphram. The height of thick diaphram which is used in the oscillator is varied. As a result, an oscillator has several different load impedances, which makes it possible to plot $G_L-V^2$ plot at the post plane. Using the $G_L-V^2$ plot, the maximum power of used Gunn diode including post is computed to be 16.8 dBm. Furthermore using the shorted and zero bias Gunn diode, the post loss used for DC biasing can be computed. Using the two losses, The maximum power of a InP Gunn diode is computed to be 18.55 dBm at 95 GHz. This result is close to a datasheet.