• Asian Pacific Journal of Cancer Prevention
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• v.15 no.1
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• pp.151-154
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• 2014

Background: Lung cancer is the most common cause of cancer-related death worldwide. The incidence of lung cancer is aproximately 7-8 thousand percent in Turkish women. In this study, we aimed to evaluate the clinical, pathological properties and survival data of female patients with lung cancer who were treated in our center. Materials and Methods: From 2007 to 2012, 50 women with lung cancer were enrolled. Patient data were evaluated retrospectively. Results: The median age was 61 (40-81). Forty patients (80%) were diagnosed with non small cell lung cancer (NSCLC), 10 patients (20%) were small cell carcinoma (SCC). Twelve (24%) patients were smokers and 13 of 16 non-smokers had a history of exposure to asbestos. The most common histologic subtype was adenocarcinoma (46%) and this accounted for 71% in patients with exposure to asbestos. The most common initial Eastern Cooperative Oncology Group (ECOG) performance score was 1 (24 patients, 48%) and initial stage was IV (25 patients, 50%) in the study group. During the median 15 months (1-96 months) followup period: 1 year overall survival (OS) was 68%, 2year overall survival was 36% and the median survival time was 19 months. According to univariate analysis, poor ECOG performance status, advanced stage, anemia and weight loss at time of diagnosis were negative prognostic factors. However, adenocarcinoma sub-type was a positive prognostic factor. Conclusions: In this study NSCLC sub-type, poor ECOG performance score, advanced stage, anemia and weight loss were prognostic factors in Turkish women with lung cancer.

• The Journal of Korean Medicine
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• v.29 no.4
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• pp.94-103
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• 2008

Objectives: The aim of this study was to determine whether celastrol, the triterpenoid component of Celastrus orbiculatus, offers neuroprotection against Parkinson's disease (PD) in mice administered 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine(MPTP). Methods: We examined how celastrol affected MPTP-induced neuronal loss of tyrosine hydroxylase (TH)-positive dopaminergic neurons in substantia nigra pars compacta (SNpc) in the midbrain of mice. C57BL/6J mice were divided into four groups: (1) saline-saline, (2) saline-celastrol, (3) MPTP-saline, and (4) MPTP-celastrol. The mice were injected intraperitoneally (i.p.) with four administrations of MPTP (18mg/kg) at 2 h intervals and then i.p. administered celastrol (3mg/kg) two times at 12 h after last celastrol administration. Expression of TH on the SNpc of brain tissues were analyzed at 7 days after the treatments by immunohistochemistry and Western blot. Results: Immunohistochemical analysis using TH antibody showed that celastrol provided significantly protective effects against MPTP-induced loss of TH-positive dopaminergic neurons in the SNpc region of the midbrain of mice. Our Western blot study also showed that celastrol significantly inhibits the MPTP-induced neuronal damage via the up-regulation of TH protein levels in MPTP mice. Conclusions: The present results suggest that it may be possible to use celastrol for the prevention of nigral degenerative disorders including PD, caused by exposure to toxic substances.

• Journal of Advanced Navigation Technology
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• v.22 no.1
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• pp.27-30
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• 2018

In this study, a 40 GHz band pass filter(BPF) employing a hair-pin structure has been designed, fabricated, and characterized for millimeter-wave wireless communication applications. Using the 3 dimensional(3-D) electromagnetic(EM) tool and design equations of the hairpin BPF, the BPF was desgned on the 5 mil-thick Duroid substrate(RT5880) with a relative dielectric constant (${\varepsilon}_r$) of 2.2. The tapping point (t) of the U-shape resonator in the input and output port has been determined using extracted an external Q-factor ($Q_e$). The coupling coefficients between the other resonators are calculated by adjusting the physical dimensions for the desired response of the BPF. The fabricated BPF was characterized using probing method on a probe station. Its measured center frequency(fc) and fractional BW are 41.6 GHz and 7.43 %, respectively. The measured return loss is below -10 dB at the pass band and the insertion loss is 3.87 dB. The fabricated BPF is as small as $9.1{\times}2.8mm^2$.

• Journal of Satellite, Information and Communications
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• v.2 no.2
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• pp.10-15
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• 2007

Small size and low profile antenna for mobile vehicular-top-mounted is needed in satellite communication services such as DBS, Satellite Internet and VSAT. In middle latitudes, the development of an array antenna which has the conformal, low profile and 45 degree beam tilted configuration, and has the high gain with sharp beamwidth, low sidelobe and low loss is required for Ku-band satellite communication. In this paper, in order to meet with these performances, an array antenna consisting of the vertical polarized waveguide longitudinal slots based on the leaky-wave mode of traveling wave antenna is proposed. An array antenna consisting of 16 leaky-wave elements is showing 30 dBi of gain, 4.9 degree of beamwidth, below than -20 dB of sidelobe level, 45 degree of beam tilt angle in center frequency. Feed network designed by waveguide cooperated feed shows good performance of wideband and low loss.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2018.05a
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• pp.59-60
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• 2018

In this paper, we studied a design method for a band-pass waveguide filter with a modified H-type resonant iris (RI) placed in a thin transverse wall of a rectangular waveguide. The horizontal straight gap at the center of a conventional H-shaped iris is modified to a U-shaped one to increase the equivalent capacitance, and the equivalent inductance is improved by changing the vertical two straight slots into C-shaped ones. A third-order band pass filter using the proposed modified H-shaped iris was designed and, it was observed that the filter operated in the frequency range of 9.22-9.75 GHz with its insertion loss of 0.5 dB and return loss of 17 dB.

• Journal of the Korean Society for Railway
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• v.17 no.1
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• pp.7-13
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• 2014

Stiffness variations and wave propagation/reflection in railway catenaries are the primary sources of contact loss between a pantograph and a railway contact wire. This paper analyzes which design parameter is more important for 200km/h conventional rail and 300km/h high-speed rail, in order to effectively reduce the contact loss. For the high-speed rail, the wave propagation and reflection in the overhead contact lines are more influential than the stiffness variation over a span. When the high-speed rail needs to speed-up, it is necessary to develop higher strength contact wires in order to increase the wave propagation speed. In addition, the dropper clamp mass should be reduced in order to alleviate the wave reflection. However, it is noted that the increase in the tension to a messenger wire could deteriorate the current collection quality, which contrasts with expectations. For the 200km/h conventional rail, the stiffness variation over a span is more influential than the wave propagation and reflection. Therefore, shortening span length, increasing the tension in the contact wire and optimizing the location of the droppers are recommended for a smoother stiffness variation over the span.

• Journal of Korea Technical Association of The Pulp and Paper Industry
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• v.43 no.4
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• pp.49-58
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• 2011

The maximum drying shrinkage velocity was proposed to verify bulk and stiffness improvement mechanism during drying according to papermaking parameters. It was based on the wet-web shrinkage behavior without the restraint of wet-web during drying, so intact drying impact could be measured. Bulking agent reduced the drying shrinkage and the maximum drying shrinkage velocity, so paper bulk increased and paper strength decreased. When adding cationic starch to stock with the bulking agent for strengthening, the bulk was increased further with additional decreasing of the drying shrinkage and the maximum drying shrinkage velocity. Paper strength also increased except tensile stiffness index with decreasing the drying shrinkage and the maximum drying shrinkage velocity. When using additional strength additives for strengthening of fiber interfaces extended by bulking agent and cationic starch, amphoteric strength additive increased paper stiffness without loss of paper bulk. It was considered that the added amphoteric strength additives were cross-linked to the stretched cationic starch and this cross-linking increased elasticity of fiber-polymer-fiber interfaces without changing the drying behavior. Paper bulk could be increased with decreasing the maximum drying shrinkage velocity. The drying shrinkage of paper also could be controlled by fiber-to-fiber bonding interfaces by the bulking agent. In this case, paper strength including stiffness was decreased by reducing fiber-to-fiber bonding but it could be improved by strengthening fiber-to-fiber interfaces with polymer complex without loss of bulk.

• Journal of Trauma and Injury
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• v.28 no.1
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• pp.15-20
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• 2015

Purpose: Vascular injuries caused by traffic, industrial accidents and by outside activities have increased in Korea. Especially, vascular injuries to the extremities can lead to limb loss and even mortality if they are not appropriately treated. The aim of the study was to evaluate the surgical outcomes of femoropopliteal vascular management after trauma. Methods: The medical records of 12 patients with femoropopliteal vascular injuries who were treated at Dankook University Hospital from 2011 to 2013 were reviewed. Iatrogenic vascular injuries were excluded. The clinical data including the causes of injury, associated injuries and surgical outcomes were analyzed retrospectively. Results: All patients were male, with a mean age of $46.8{\pm}16.3years$ (range: 26~69 years). The causes of vascular injuries were four traffic accidents, three industrial accidents, two iron plates, one outside activity, one glass injury and one knife injury. The average transit time between the place of the accident place and the emergency department was $3.0{\pm}2.1$ (0.5~12.5) hours, and the average preparation time for surgery was $8.0{\pm}6.7$ (1.7~23.3) hours. The anatomic injuries included the popliteal vessel in seven cases and the femoral vessel in five cases. The average Injury Severity Score (ISS) was $12.0{\pm}5.0$ (5~17), and the average Mangled Extremity Severity Score (MESS) was $5.7{\pm}2.1$ (2~9). The operation methods were four interposition grafts, three end-to-end anastomoses, two direct repairs and three patch angioplasties. One case required amputation of the injured extremity. Conclusion: Early recognition and revascularization of the injured vessel are mandatory to reduce limb loss and to obtain satisfactory outcomes. Therefore, careful/rapid evaluation of the vascular injuries and timely/successful surgical treatment are the keys to salvaging an injured limb.

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.43 no.1 s.307
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• pp.31-38
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• 2006

In this paper, we consider one-step-ahead control of waveform parameters (pulse amplitudes and lengths, and FM sweep rate) as well as detection thresholds for optimal range and range-rate tracking in clutter. The optimal control of the combined parameter set minimizes a tracking performance index under a set of parameter constraints. The performance index includes the probability of track loss and a function of estimation error covariances. The track loss probability and the error covariance are predicted using a hybrid conditional average algorithm The effect of the false alarms and clutter interference is taken into account in the prediction. Tracking performance of the one-step-ahead control is presented for several examples and compared with a control strategy heuristically derived from a finite horizon optimization.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.47 no.4
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• pp.38-42
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• 2010

In this paper, a design method of the compact narrow band filter on the microstrip board is proposed using slot-type split spiral resonators. The design technique of this filter is based on cascading filter stages consisting of the combination of slot-type split spiral resonators, capacitive gaps between patches, and inductive grounded stubs with the meander configuration. By these means, it was possible to get the nearly symmetric frequency responses, adjustable bandwidths, compact sizes. And also excellent characteristic of the out-of-band rejection is achieved in contrast to the conventional filter design technique. The measured insertion loss shows good results about -3.47dB at the center frequency($f_0$=1GHz) and passband return loss is less than -12.62dB. The 3dB fractional bandwidth(FBW) is approximately 7.3%. The results of the frequency response measured on the fabricated band pass filter substrate show satisfactory agreement with the simulated frequency responses by the MWS(Microwave Studio) of CST in the region of interest.