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Production of Lipocortin-1$_{1-185}$ Using A Recombinant of Escherichia coli.

  • Lee, Kyung-Il;Oh, Kyung-Hee;Lee, Jung-Hyun;Na, Do-Sun;Lee, Kye-Joon
    • Journal of Microbiology
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    • v.35 no.2
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    • pp.123-126
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    • 1997
  • The aim of the present study was to optimize culture condition for the expression of lipocortin-1$_{1-185}$ in a recombinant of Escherichia coli using batch system. Plasmid (pHT22) carrying lipocortin-1$_{1-185}$ gene was well maintained in the recombinant with the addition of amplicillin as a selection pressures. Optimum temperature was 28$^{\circ}C$ for seed culture and 4$0^{\circ}C$ for main culture and the optimum pH was 7.0. The production of Lipocortin-1$_{1-185}$ was closely associated with cell growth and related to plasmid amplification.

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Introduction of FPSO DPM System and Design Consideration Factor at the Early Design Phase (FPSO DPM 시스템 소개 및 초기 설계 시 고려사항)

  • Lee, Choong Yeol;Jeon, Kwang-Heon;Lee, Hee Sung;Kwon, Youngrag
    • Special Issue of the Society of Naval Architects of Korea
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    • 2013.12a
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    • pp.97-102
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    • 2013
  • As the offshore oil and gas upstream industry moves into deeper water, the FPSOs are the cost-effective solution. In the harsh environment such as in North Sea, station keeping and heading control capability obtained through the DP and Position Mooring (DPM) system of FPSOs play important roles to keep the safety. This paper introduces the concept, function and sub-system of the DPM systems which has been applied for the North Sea FPSOs since the late 1980s. The requirements and guidelines of some internationally recognized standards are also described, which are important to build the design basis at the early phases of the project.

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Treatments of Unilateral Neglect Syndrome: Review (일측성 무시 증후군 치료에 대한 고찰)

  • Shin Du-chul;Chae Soon-yub;Kim Ju Sang;Lee Yun Seob
    • The Journal of Korean Physical Therapy
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    • v.16 no.2
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    • pp.156-168
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    • 2004
  • Unilateral neglect is a common behavioral syndrome in patients following stroke. Unilateral neglect is characterized by the failure to report or responds to people or object presented to the side opposite a brain lesion. The patients with unilateral neglect are severely disabled in all daily activities, have a poor rehabilitation outcome and therefore require professional assessment and treatment This article reviews recent efficacy of rehabilitation techniques includings; drug, cueing, scanning training, prism lense, eye patching, trunk rotation, neck vibration, TENS, limb activation, video feedback. The purpose of this reviews are: to clarify the different types of neglect, as a basis for understanding the tests and measures of unilateral neglect and give information about recent treatments.

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Disseminated Cysticercosis

  • Park, Soo-Yong;Kong, Min-Ho;Kim, Jung-Hee;Song, Kwan-Young
    • Journal of Korean Neurosurgical Society
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    • v.49 no.3
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    • pp.190-193
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    • 2011
  • Disseminated cysticercosis is a rare form of cysticercosis in which the cysticerci spread out through the whole body. We report the first case of a 39-year-old Mongolian with disseminated cysticercosis. He visited our hospital with generalized tonic-clonic seizure. After extensive investigation from brain computed tomography (CT), spine magnetic resonance imaging (MRI), whole body MRI and pathologic biopsy, he was diagnosed as having cysticercosis involving the brain, subcutaneous tissue, and skeletal muscles through the whole body. We treated him with the albendazole in which case the followed MRI showed that numbers of cystic lesions were copiously decreased. We report an unsual case of disseminated cysticercosis treated with medical therapy.

The analysis of difference in the relative renal function based on total counts method and average counts method (총 계수 분석법과 평균 계수 분석법에 따른 신장 기능의 차이 분석)

  • JUNG WOO-YOUNG;CHO SHEE-MAN;PARK SEUNG-YONG;SHIM DONG-OH
    • Journal of The Korean Radiological Technologist Association
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    • v.29 no.1
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    • pp.44-49
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    • 2003
  • Purpose : $^{99m}Tc-DMSA$ renal scan can be used in the evaluation of relative renal function and some anatomy. The relative renal function can be assess by measurement of $^{99m}Tc-DMSA$ uptake by the individual kidney. Renal counts

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A Study on the Application of Artificial Intelligence in Symbolic Execution: Usage in fuzzing and vulnerability detection (기호 실행에서의 인공 지능 적용에 대한 연구: 퍼징과 취약점 탐지에서의 활용)

  • Ha, Whoi Ree;Ahn, Sunwoo;Kim, Hyunjun;Paek, Yunheung
    • Annual Conference of KIPS
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    • 2020.05a
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    • pp.582-584
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    • 2020
  • 기호 실행 (symbolic execution)은 프로그램을 특정 상태로 구동하는 입력 값을 찾는 코드 분석기법이다. 이를 사용하면 자동화 소프트웨어 테스트 기법인 퍼징 (fuzzing)을 훨씬 효율적으로 사용하여 더 많은 보안 취약점을 찾을 수 있지만, 기호 실행의 한계점으로 인하여 쉽게 적용할 수 없었다. 이를 해결하기 위해 인공 지능을 활용한 방법을 소개하겠다.

A Study on Electron-beam Lithography Simulation for Resist Surface Roughness Prediction (Resist 표면 거칠기 예측을 위한 전자빔 리소그라피 시뮬레이션에 관한 연구)

  • Kim, Hak;Han, Chang-Ho;Lee, Ki-Yong;Lee, Woo-Jin;Chun, Kuk-Jin
    • Proceedings of the IEEK Conference
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    • 2002.06b
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    • pp.45-48
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    • 2002
  • This paper discusses the surface roughness of negative chemically amplified resists, SAL601 exposed by I-beam direct writing. system. Surface roughness, as measured by atomic force microscopy, have been simulated and compared to experimental results. Molecular-scale simulator predicts the roughness dependence on material properties and process conditions. A chemical amplification is made to occur in the resists during PEB process. Monte-Carlo and exposure simulations are used as the same program as before. However, molecular-scale PEB simulation has been remodeled using a two-dimensional molecular lattice representation of the polymer matrix. Changes in surface roughness are shown to correlate with the dose of exposure and tile baking time of PEB process. The result of simulation has a similar tendency with that of experiment.

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Neuron Circuit Using a Thyristor and Inter-neuron Connection with Synaptic Devices

  • Ranjan, Rajeev;Kwon, Min-Woo;Park, Jungjin;Kim, Hyungjin;Park, Byung-Gook
    • JSTS:Journal of Semiconductor Technology and Science
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    • v.15 no.3
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    • pp.365-373
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    • 2015
  • We propose a simple and compact thyristor-based neuron circuit. The thyristor exhibits bi-stable characteristics that can mimic the action potential of the biological neuron, when it is switched between its OFF-state and ON-state with the help of assist circuit. In addition, a method of inter-neuron connection with synaptic devices is proposed, using double current mirror circuit. The circuit utilizes both short-term and long-term plasticity of the synaptic devices by flowing current through them and transferring it to the post-synaptic neuron. The double current mirror circuit is capable of shielding the pre-synaptic neuron from the post synaptic-neuron while transferring the signal through it, maintaining the synaptic conductance unaffected by the change in the input voltage of the post-synaptic neuron.

Impact of the Interval between Previous Endoscopic Exam and Diagnosis on the Mortality and Treatment Modality of Undifferentiated-Type Gastric Cancer

  • Lee, Ayoung;Chung, Hyunsoo;Lee, Hyuk-Joon;Cho, Soo-Jeong;Kim, Jue Lie;Ahn, Hye Seong;Suh, Yun-Suhk;Kong, Seong-Ho;Choe, Hwi Nyeong;Yang, Han-Kwang;Kim, Sang Gyun
    • Journal of Gastric Cancer
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    • v.21 no.2
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    • pp.203-212
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    • 2021
  • Purpose: The impact of the interval between previous endoscopy and diagnosis on the treatment modality or mortality of undifferentiated (UD)-type gastric cancer is unclear. This study aimed to investigate the effect of endoscopic screening interval on the stage, cancer-related mortality, and treatment methods of UD-type gastric cancer. Materials and Methods: We reviewed the medical records of newly diagnosed patients with UD gastric cancer in 2013, in whom the interval between previous endoscopy and diagnosis could be determined. The patients were classified into different groups according to the period from the previous endoscopy to diagnosis (<12 months, 12-23 months, 24-35 months, ≥36 months, and no history of endoscopy), and the outcomes were compared between the groups. In addition, patients who underwent endoscopic and surgical treatment were reclassified based on the final treatment results. Results: The number of enrolled patients was 440, with males representing 64.1% of the study population; 11.8% of the participants reported that they had undergone endoscopy for the first time in their cancer diagnosis. The percentage of stage I cancer at diagnosis significantly decreased as the interval from the previous endoscopy to diagnosis increased (65.4%, 63.2%, 64.2%, 45.9%, and 35.2% for intervals of <12 months, 12-23 months, 24-35 months, ≥36 months, and no previous endoscopy, respectively, P<0.01). Cancer-related mortality was significantly lower for a 3-year interval of endoscopy (P<0.001). Conclusions: A 3-year interval of endoscopic screening reduces gastric-cancer-related mortality, particularly in cases of UD histology.