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Atypical Radiologic Manifestation of NARP Mimicking MELAS: a Case Report

  • Lee, Youdae;Lee, Donghoon;Hwang, Hokyeong
    • Investigative Magnetic Resonance Imaging
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    • v.22 no.2
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    • pp.119-122
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    • 2018

  • Neurogenic weakness, ataxia and retinitis pigmentosa (NARP) syndrome is a rare maternally inherited mitochondrial disorder. Radiologic findings in NARP syndrome are varied; they include cerebral and cerebellar atrophy, basal ganglia abnormalities, and on rare occasions, leukoencephalopathy. This article describes an extremely rare case of NARP syndrome mimicking mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS).

  • https://doi.org/10.13104/imri.2018.22.2.119 인용 PDF KSCI

Influence of Digestion Temperature on the Extraction of Soil Heavy Metal by Korean Ministry of Environment Standard Method (토양오염공정시험기준에 따른 토양 중금속 추출 시 분해 온도가 미치는 영향)

  • Shin, Gunhwan;Park, Hyunjung;Oh, Kiseok;Jung, Gain;Shin, Dongjun;Lee, Goontaek;Joo, Changkyu;Lee, Sangmo;Kim, Taeseung
    • Journal of Soil and Groundwater Environment
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    • v.27 no.3
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    • pp.11-21
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    • 2022

  • The purpose of this study was to evaluate the influences of digestion temperature on the extraction of heavy metals from soil using the standard method established by Korean Ministry of Environment (KMES). A total of 7 heavy metals (As, Cd, Cr, Cu, Ni, Pb and Zn) in soil samples were extracted at varying digestion temperatures [(66 ± 2.0)℃, (73 ± 1.9)℃, (80 ± 1.3)℃, (85 ± 1.7)℃, (92 ± 2.0)℃, (98 ± 1.7)℃]. As, Cd, Cu, Pb and Zn concentrations remained relatively constant over the temperature range, but Ni and Cr concentrations greatly varied with the digestion temperature. The extent of variation in extraction efficiencies as compared to the concentration obtained at 66℃ was in following order; Ni (7.09% ~ 35.42%) > Cr (4.79% ~ 25.40%) > Zn (3.99% ~ 17.52%) > Cu (2.22% ~ 19.34%) > As (3.54% ~ 8.26%) > Cd (-5.08% ~ 1.08%) > Pb (-4.71% ~ -1.70%). The accuracy for certified reference materials at the digestion temperature of 80 and 85℃ was 98.7% ~ 105.8%. Therefore, digestion temperature of 80℃ ~ 85℃ is suggested to obtain reliable and reproducible data when the standard method by Korean Ministry of Environment is employed to analyze multiple heavy metal components in soil samples.

  • https://doi.org/10.7857/JSGE.2022.27.3.011 인용 PDF KSCI HTML

Study on Quality Changes Caused by Rancidity and Methods to Reduce Rancidity for Domestically Distributed Herbal Medicines (유통 한약재의 산패에 따른 품질변화 및 산패 저감화 연구)

  • Young-Ae Park;Suk-Kyung Ko;Hyun-Kyung Lee;Eun-Jung Choi;Sung-Cho Hong;Yun-Seon Park;Ji-Hun Jung;Ju-Sung Park;Yong-Seung Shin
    • Korean Journal of Pharmacognosy
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    • v.54 no.2
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    • pp.80-87
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    • 2023

  • Rancidity changes were examined for 6 herbal medicines, namely Persicae Semen, Armeniacae Semen, Lini Semen, Trichosanthis Semen, Arecae Semen, Myristicae Semen known to have relatively high fat content. In order to reduce rancidity of herbal medicines, samples were stored at 3 different conditions of room, refrigerating and freezing temperatures, and the rancidity was measured for 10 months with every 2 month interval. Fat content was extracted by using ethyl ether, and acid values and peroxide values, which are generally accepted indicators of fat rancidity, were measured. When storing Persicae Semen, Lini Semen and Arecae Semen at room temperature, the acid values increased as the storage period increased, and it was higher than when stored in refrigeration or freezing. The measurement of peroxide value showed more significantly higher initial degree of rancidity when Persicae Semen, Trichosanthis Semen, Arecae Semen and Myristicae Semen were stored at room temperature. It was observed that storing herbal medicines in refrigeration or freezing inhibited their rancidity compared to storing them at room temperature. To investigate the quality changes according to rancidity, the analysis of aflatoxins and indicator components showed that aflatoxins B1 and B2 were detected in Armeniacae Semen, Arecae Semen and Myristicae Semen, and the amount of amygdalin was well maintained within the specification standard.

  • https://doi.org/10.22889/KJP.2023.54.2.80 인용 PDF HTML

Survey on the Pesticides Suspected as an Endocrine Disrupter In Agricultural Products Distributed in Seoul (서울지역 유통 농산물 중 내분비계 장애 추정농약의 잔류실태 조사)

  • Kim, Ouk-Hee;Park, Sung-Kyu;Choi, Young-Hee;Seoung, Hyun-Jung;Han, Sung-Hee;Lee, Young-Ju;Jang, Jung-Im;Kim, Yun-Hee;Jo, Han-Bin;Park, Geon-Yong;Yu, In-Sil;Han, Ki-Young
    • The Korean Journal of Pesticide Science
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    • v.15 no.1
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    • pp.36-47
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    • 2011

  • This study was performed to investigate the contaminated status of endocrine disruptor-suspected pesticides in agricultural products distributed in northern Seoul in 20l0. We analyzed 33 kinds of pesticides by multiresidue analysis method in 3,081 samples. Twelve pesticidcs were detected 600 times and violated 22 times from the agricultural products. The highest frequency of detection was procymidone and that of violation was endosulfan. The highest rates of detection divided violation times as diazinon. In agricultural products, 466 samples had pesticide residues and 22 samples violated the maximum residue limits (MRLs). Agricultural products were also classified by type and red pepper powder belonged to the others was the highest detection rate at 70.7%, fruiting vegetables 35.3%, tea leaves 23.6%, stalk and stem vegetables 21.2%, fruits 14.6% and leafy vegetables 11.2%. The rates of violation sample were stalk and stem vegetables 1.1%, leafy vegetables 1.0% and roots and tubers 0.4%. Leek was to be managed primarily because it had the high detection and violation ratio and was detected together several pesticides.

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