• Journal of the Society of Cosmetic Scientists of Korea
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• v.43 no.4
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• pp.309-320
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• 2017

In this study, the antioxidative effects and component analysis of 50% ethanol extract, ethyl acetate fraction and aglycone fraction obtained from Annona muricata leaf were investigated. Free radical scavenging activities were performed by 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay, total antioxidant capacities were estimated using luminol-dependent chemiluminescence assay and $^1O_2$ quenching effects were estimated. Free radical scavenging activities ($FSC_{50}$) of 50% ethanol extract, ethyl acetate fraction and aglycone fraction were 45.6, 29.8 and $18.0{\mu}g/mL$, and total antioxidant capacities ($OSC_{50}$) were 4.4, 1.1 and $2.8{\mu}g/mL$, respectively. As a result of $^1O_2$ quenching experiment, ethyl acetate and aglycone fraction showed similar activities to L-ascorbic acid used as a comparative control. The cellular protective effects of 50% ethanol extract on the $^1O_2-induced$ cellular damage of human erythrocytes were exhibited at concentration-dependent ($5-50{\mu}g/mL$). TLC and HPLC were used to analyse components in the ethyl acetate fraction and aglycone fraction of Annona muricata leaf. In ethyl acetate fraction, rutin (quercetin-3-O-rutinoside), kaempferol-3-O-neohesperidoside, nicotiflorin (kaempferol-3-O-rutinoside), p-coumaric acid were identified. In aglycone fraction, kaempferol was identified. These results suggest that the extracts of Annona muricata leaf have the applicability as antioxidant cosmeceutical ingredients.

• Proceedings of the Korea Institutes of Information Security and Cryptology Conference
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• 2006.06a
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• pp.365-369
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• 2006

Multiple Message Authentication Codes can be represented by one of the Short MAC, Bloom Filter or Compressed Bloom Filler to reduce communication overheads. However, this will inevitably increase false positive rate (fpr) which is a false authentication probability of adversarial messages in trade-off of communication efficiency. While the simple short MAC scheme has the lowest fpr, one cannot choose arbitrary authenticator size. Bloom filter, randomized data structure often used for membership queries, can represent multiple MACs more flexibly with slightly higher fpr. Furthermore, compressed Bloom filter has the same fpr with the short MAC while maintaining its flexibility. Through our detailed analysis, we show that pros and cons of the three schemes are scenario specific. Therefore one can choose appropriate scheme under given parameters to achieve both communication efficiency and security based on our results.

• Proceedings of the KOSOMBE Conference
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• v.1996 no.11
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• pp.349-350
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• 1996

Using FEM, we analyzed the stress changes on early osteonecrosis of femoral head as the necrotic area increases. A 3D FEM model of proximal femur was made from the CT scam data of fresh frozen adult proximal femur with the material properties from literature. The model consisted of 5994 elements and 5275 nodes. FE analyses were peformed using MSC/NASTRAN. At normal states, stress transmission is mainly along the primary compression trabeculae(PCT). Until 60% involvement of PCT with necrotic lesion, stress transmission is still along the remained PCT. When the PCT involvement is from 60% to 85%, stress transmission is along the PCT and margin of the necrotic lesion. When involvement is more than 85%, stress is mostly transferred to posterior part of femoral head.

• Proceedings of the KIEE Conference
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• 1993.07b
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• pp.971-973
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• 1993

Deflection Yoke(the following, DY) is the important electric device of CRT which deflects R, G, B beans influencing magnetic field produced by yoke coils. Recently, DY is designed to the saddle/saddle type of coils, being proposed for high-definite and high-efficient CRT. This paper presents the optimization of pin-sectioned saddle coil's shape for minimizing gap between desired and practical deflections of electron beams by using Genetic Algorithm. Evolution Startegy is utilized in this paper, since evolution strategy is a kind of genetic algorithms finding the optimized values by choicing the better generation with comparing the parents and their children. Here, the children are generated by only mutations from the normal random variables. Evolution strategy has shown better powerful converge rate than the other genetic algorithms becuase of using only the mutation-operator.

• Korean Journal of Radiology
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• v.24 no.8
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• pp.719-728
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• 2023

Radiofrequency ablation (RFA) has been widely used to manage hepatocellular carcinomas (HCCs) equal to or smaller than 3 cm. No-touch RFA has gained attention and has recently been implemented in local ablation therapy for HCCs, despite its technical complexity, as it provides improved local tumor control compared to conventional tumor-puncturing RFA. This article presents the practice guidelines for performing no-touch RFA for HCCs, which have been endorsed by the Korean Society of Image-Guided Tumor Ablation (KSITA). The guidelines are primarily designed to assist interventional oncologists and address the limitations of conventional tumor-puncturing RFA with describing the fundamental principles, various energy delivery methods, and clinical outcomes of no-touch RFA. The clinical outcomes include technical feasibility, local tumor progression rates, survival outcomes, and potential complications.

• Proceedings of the KIEE Conference
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• 2008.07a
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• pp.307-308
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• 2008

This paper presents the effects of operating Backup Dispatch Center as a System Dispatch Center(SDC). SDC operates the 154kV transmission lines outside of Seoul metropolitan area, and acts as the backup dispatch center in case of central dispatch center's failure. With SDC, it became possible not only to divide operation of Korean transmission lines to separate control centers according to voltage and region, but to clear faults faster and more accurately. It has paved the way to improve power system reliability and advance the power system operation in general.

• Proceedings of the KIEE Conference
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• 1994.07a
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• pp.229-231
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• 1994

In recent years, as the industry has been highly developed and precised, its driving and control system have been changed, what is more, revolutionized. The requirements of these change are more accuracy, more high efficiency, more miniaturized size and more servo functions. Step motor has been adopted for driving servo systems, because of easier controllability, open-loop control, high position accuracy at low speed. In this paper, we deal with developing step motor system, and describe the procedure that contains design, analysis. testing characteristics.

• Journal of Mechanical Science and Technology
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• v.14 no.8
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• pp.861-866
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• 2000

Flow induced shape change is important for spatial interpretation of vascular response and for understanding of mechanotransduction in a single cell. We investigated the possible shapes of endothelial cell (EC) in a mathematical model and compared these with experimental results. The linearized analytic solution from the sinusoidal wavy wall and Stokes flow was applied with the constraint of EC volume. The three dimensional structure of the human umbilical vein endothelial cell was visualized in static culture or after various durations of shear stress (20 $dyne/cm^2$ for 5, 10, 20, 40, 60, 120min). The shape ratio (width: length: height) of model agreed with that of the experimental result, which represented the drag force minimizing shape of stream-lining. EC would be streamlined in order to accommodate to the shear flow environmented by active reconstruction of cytoskeletons and membranes through a drag force the sensing mechanism.

• Environmental Mutagens and Carcinogens
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• v.15 no.2
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• pp.81-87
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• 1995

The clastogenic activity of capsaicin, a major pungent and irritating constituent of hot chili pepper, was evaluated in cultured human lymphocytes. Capsaicin (125, 250, and 500 $\mu$M) caused cytogenetic damage as determined by increased frequency of chromosome/chromatid aberrations compared to the solvent control. The mitotic indices were also decreased in a concentration-related manner in capsaicin-treated cells. Moreover, capsaicin suppressed [$^3$]thymidine incorporation into lymphocytes. The clastogenicity and cytotoxicity of capsaicin towards human lymphocytes were evident without an external metabolic activation system. Taken together, these findings suggest that capsaicin is a genotoxic agent and may thus represent a potential health hazard in humans.

• Molecules and Cells
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• v.39 no.12
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• pp.841-846
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• 2016

Local protein synthesis mediates precise spatio-temporal regulation of gene expression for neuronal functions such as long-term plasticity, axon guidance and regeneration. To reveal the underlying mechanisms of local translation, it is crucial to understand mRNA transport, localization and translation in live neurons. Among various techniques for mRNA analysis, fluorescence microscopy has been widely used as the most direct method to study localization of mRNA. Live-cell imaging of single RNA molecules is particularly advantageous to dissect the highly heterogeneous and dynamic nature of messenger ribonucleoprotein (mRNP) complexes in neurons. Here, we review recent advances in the study of mRNA localization and translation in live neurons using novel techniques for single-RNA imaging.