• Title/Summary/Keyword: center in Seoul

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Post-Coronary Artery Bypass Grafting Myocardial Ischemia Caused by an Overgrown Left Internal Thoracic Artery Side Branch

  • Kim, Eung Re;Oh, Se Jin;Kang, Hyun-Jae;Kim, Ki-Bong
    • Journal of Chest Surgery
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    • v.47 no.5
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    • pp.465-467
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    • 2014
  • We present a patient who developed recurrent angina after coronary artery bypass grafting (CABG). Myocardial single-photon emission computed tomography (SPECT) demonstrated deterioration in the myocardial perfusion, and coronary angiography revealed an overgrown side branch of the grafted left internal thoracic artery (ITA); otherwise, there were no significant changes compared with previous imaging studies obtained after the CABG. After percutaneous embolization of the grafted left ITA side branch, the angina was resolved and myocardial SPECT showed improved perfusion.

Update on genetic screening and treatment for infertile men with genetic disorders in the era of assisted reproductive technology

  • Lee, Seung Ryeol;Lee, Tae Ho;Song, Seung-Hun;Kim, Dong Suk;Choi, Kyung Hwa;Lee, Jae Ho;Kim, Dae Keun
    • Clinical and Experimental Reproductive Medicine
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    • v.48 no.4
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    • pp.283-294
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    • 2021
  • A genetic etiology of male infertility is identified in fewer than 25% of infertile men, while 30% of infertile men lack a clear etiology, resulting in a diagnosis of idiopathic male infertility. Advances in reproductive genetics have provided insights into the mechanisms of male infertility, and a characterization of the genetic basis of male infertility may have broad implications for understanding the causes of infertility and determining the prognosis, optimal treatment, and management of couples. In a substantial proportion of patients with azoospermia, known genetic factors contribute to male infertility. Additionally, the number of identified genetic anomalies in other etiologies of male infertility is growing through advances in whole-genome amplification and next-generation sequencing. In this review, we present an up-to-date overview of the indications for appropriate genetic tests, summarize the characteristics of chromosomal and genetic diseases, and discuss the treatment of couples with genetic infertility by microdissection-testicular sperm extraction, personalized hormone therapy, and in vitro fertilization with pre-implantation genetic testing.

The Patterns of Residential Changes among Households in the City of Seoul (서울시 거주 가구의 주거입지 변화 패턴)

  • 윤복자
    • Journal of the Korean housing association
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    • v.8 no.2
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    • pp.49-59
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    • 1997
  • The purpose of this study is to analyze Phenomenon of the residential movement and important factors in the city of Seoul. First, The patterns of residential location during 1975-1994 in terms of macro aspects are to be investigated. Second, Residential patterns among households based on the literature survey data in terms of micro aspects are to be indentified. Methodology applied to the study is regression analysis using 1975-1994statistical data and content analysis based on the literature survey. The results of this study are as follows : 1) The factors of residential movement in the city of Seoul are explained by the changes of the economic structure, residential environment, individual characteristics, and housing policy. That is. the development of transportation systems, the number of homeownership scheme holders, crime rates, increase of residential areas effect on the decrease of the population in the city center of Seoul 2) According to the income groups and resident characteristics, Residential location patterns are different in residential location choice and the scope of spatial migration.

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Automated Detection and Segmentation of Bone Metastases on Spine MRI Using U-Net: A Multicenter Study

  • Dong Hyun Kim;Jiwoon Seo;Ji Hyun Lee;Eun-Tae Jeon;DongYoung Jeong;Hee Dong Chae;Eugene Lee;Ji Hee Kang;Yoon-Hee Choi;Hyo Jin Kim;Jee Won Chai
    • Korean Journal of Radiology
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    • v.25 no.4
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    • pp.363-373
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    • 2024
  • Objective: To develop and evaluate a deep learning model for automated segmentation and detection of bone metastasis on spinal MRI. Materials and Methods: We included whole spine MRI scans of adult patients with bone metastasis: 662 MRI series from 302 patients (63.5 ± 11.5 years; male:female, 151:151) from three study centers obtained between January 2015 and August 2021 for training and internal testing (random split into 536 and 126 series, respectively) and 49 MRI series from 20 patients (65.9 ± 11.5 years; male:female, 11:9) from another center obtained between January 2018 and August 2020 for external testing. Three sagittal MRI sequences, including non-contrast T1-weighted image (T1), contrast-enhanced T1-weighted Dixon fat-only image (FO), and contrast-enhanced fat-suppressed T1-weighted image (CE), were used. Seven models trained using the 2D and 3D U-Nets were developed with different combinations (T1, FO, CE, T1 + FO, T1 + CE, FO + CE, and T1 + FO + CE). The segmentation performance was evaluated using Dice coefficient, pixel-wise recall, and pixel-wise precision. The detection performance was analyzed using per-lesion sensitivity and a free-response receiver operating characteristic curve. The performance of the model was compared with that of five radiologists using the external test set. Results: The 2D U-Net T1 + CE model exhibited superior segmentation performance in the external test compared to the other models, with a Dice coefficient of 0.699 and pixel-wise recall of 0.653. The T1 + CE model achieved per-lesion sensitivities of 0.828 (497/600) and 0.857 (150/175) for metastases in the internal and external tests, respectively. The radiologists demonstrated a mean per-lesion sensitivity of 0.746 and a mean per-lesion positive predictive value of 0.701 in the external test. Conclusion: The deep learning models proposed for automated segmentation and detection of bone metastases on spinal MRI demonstrated high diagnostic performance.

Evaluation of the Dietary Diversity and Nutrient Intakes in Obese Adults (비만성인의 영양소 섭취량 및 식사 다양성 평가)

  • Kim, So-Hye;Kim, Ju-Young;Ryu, Kyoung-A;Sohn, Cheong-Min
    • Korean Journal of Community Nutrition
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    • v.12 no.5
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    • pp.583-591
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    • 2007
  • The purpose of this study was to assess the diet diversity, food habit and nutrient intake of obese adults who were visiting the health promotion center. This study was accomplished with the 138 obese adults (men = 103, women= 35) aged over 20 years old whose BMI were above $25 kg/m^2$. Nutrient adequacy ratio (NAR), the number of foods (Dietary Variety Score DVS), and food group consumed (Dietary Diversity Score, DDS) by using the data from the three days record were analyzed and the food habit and lifestyle were assessed by self reporting questionnaire. The average enemy intake of men was 2150.2 kcal which was significantly higher than that of women (p < 0.05). The intake ratio of carbohydrate, protein and fat over total energy was 54.8% : 19.3% : 25.8% in men, 59.5% : 17.8% : 22.6% in women respectively. Frequency of the breakfast in a week above 4, $2{\sim}3$ time and under one time was 75.7% 10.7% and 9.7% in men 77.1%, 5.7% and 14.3% in women respectively. frequency of eating between meals in a day under one time was 73.8% in men, 57.1% in women (p < 0.05). The average DDS and DVS was $3.63{\pm}0.07$ and $14.10 {\pm}3.45$, respectively which was significantly correlated with MAR (r=0.40 in DDS, r=0.64 in DVS, p < 0.01). The most frequent style of food pattern was DMGFV = 01101 in 35% of men, and DMGFV= 01111 in 37.1% of women. Our results show that dietary diversity and variety are useful parameters far evaluating nutrient intakes in obese adults. These findings suggest that nutritional education based on obese persons' eating behavior and eating diversity may be required to increase educational efficiency of weight control programs.

Functional Reorganization Associated with Semantic Language Processing in Temporal Lobe Epilepsy Patients after Anterior Temporal Lobectomy: A Longitudinal Functional Magnetic Resonance Image Study

  • Kim, Jae-Hun;Lee, Jong-Min;Kang, Eun-Joo;Kim, June-Sic;Song, In-Chan;Chung, Chun-Kee
    • Journal of Korean Neurosurgical Society
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    • v.47 no.1
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    • pp.17-25
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    • 2010
  • Objective: The focus of this study is brain plasticity associated with semantic aspects of language function in patients with medial temporal lobe epilepsy (mTLE) Methods: Using longitudinal functional magnetic resonance imaging (fMRI), patterns of brain activation were observed in twelve left and seven right unilateral mTLE patients during a word-generation task relative to a pseudo-word reading task before and after anterior temporal section surgery. Results: No differences were observed in precentral activations in patients relative to normal controls (n = 12), and surgery did not alter the phonological-associated activations. The two mTLE patient groups showed left inferior prefrontal activations associated with semantic processing (word-generation>pseudo-word reading), as did control subjects. The amount of semantic-associated activation in the left inferior prefrontal region was negatively correlated with epilepsy duration in both patient groups. Following temporal resection, semantic-specific activations in inferior prefrontal region became more bilateral in left mTLE patients, but more left-lateralized in right mTLE patients. The longer the duration of epilepsy in the patients, the larger the increase in the left inferior prefrontal semantic-associated activation after surgery in both patient groups. Semantic activation of the intact hippocampus, which had been negatively correlated with seizure frequency, normalized after the epileptic side was removed. Conclusion: These results indicate alternation of semantic language network related to recruitment of left inferior prefrontal cortex and functional recovery of the hippocampus contralateral to the epileptogenic side, suggesting an intra- and inter-hemispheric reorganization following surgery.

A Successful Bilateral Lung Transplantation in a Patient with High Panel Reactive Antibody and Positive Cross Matching

  • Bok, Jin San;Jun, Jae Hyun;Lee, Hyun Joo;Park, In Kyu;Kang, Chang Hyun;Yang, Jaeseok;Kim, Young Tae
    • Journal of Chest Surgery
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    • v.47 no.4
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    • pp.420-422
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    • 2014
  • A 44-year-old pregnant female patient gave stillbirth while being treated for pneumonia. She developed acute respiratory failure, which resulted in mechanical ventilator support. Diagnostic lung biopsy revealed a cryptogenic organizing pneumonia. The patient's condition deteriorated and a venous-venous extracorporeal membrane oxygenation was placed. She was listed for lung transplantation. Because of her worsening condition lung transplantation was performed despite positive cross matching result. She was treated with rituximab, intravenous immunoglobulin, and plasmapheresis and recovered without event. There is no sign of rejection at the time of last follow-up.

Electrically Controllable Fiber Bragg Gratings with Liquid Crystal Cladding

  • Baek Seungin;Roh Sookyoung;Na Jun-Hee;Kwon Jaejoong;Yoon Ilyong;Chung Seunghwan;Jeong Cherlhyun;Lee Sin-Doo;Lee Byoungho;Jeong Yoonchan
    • Journal of the Optical Society of Korea
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    • v.9 no.3
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    • pp.123-128
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    • 2005
  • An electrically controllable fiber Bragg grating inscribed in a hydrogen-loaded standard single-mode fiber with liquid-crystal cladding is presented. Control of the optic axis of liquid crystals by means of external electric fields results in the change of reflectivity and Bragg wavelength of the grating. The increase of surrounding refractive index of a fiber makes effective refractive index of a propagation mode higher, which results in high field confinement and longer Bragg wavelength. The reduction of the fiber diameter by chemical etching process improves the long-range ordering of liquid-crystal molecules and reduces controlling voltage. The tunable ranges of reflectivity and Bragg wavelength of the liquid crystal-cladding fiber Bragg grating were $\~4.6dB\;and\;\~0.3nm$, respectively.