• BMB Reports
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• v.57 no.3
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• pp.149-154
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• 2024

The stomach has emerged as a crucial endocrine organ in the regulation of feeding since the discovery of ghrelin. Gut-derived hormones, such as ghrelin and cholecystokinin, can act through the vagus nerve. We previously reported the satiety effect of hypothalamic clusterin, but the impact of peripheral clusterin remains unknown. In this study, we administered clusterin intraperitoneally to mice and observed its ability to suppress fasting-driven food intake. Interestingly, we found its synergism with cholecystokinin and antagonism with ghrelin. These effects were accompanied by increased c-fos immunoreactivity in nucleus tractus solitarius, area postrema, and hypothalamic paraventricular nucleus. Notably, truncal vagotomy abolished this response. The stomach expressed clusterin at high levels among the organs, and gastric clusterin was detected in specific enteroendocrine cells and the submucosal plexus. Gastric clusterin expression decreased after fasting but recovered after 2 hours of refeeding. Furthermore, we confirmed that stomachspecific overexpression of clusterin reduced food intake after overnight fasting. These results suggest that gastric clusterin may function as a gut-derived peptide involved in the regulation of feeding through the gut-brain axis.

• Journal of Korean Society for Atmospheric Environment
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• v.29 no.3
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• pp.317-324
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• 2013

This research assessed the surface properties of modified activated carbons with three different acids and five different metals for ammonia gas removal. Raw bituminous coal-based activated carbon ($4{\times}8$ mesh) had low adsorption capacity of 0.72 mg $NH_3/g$ based on the analysis in the column adsorption experiment. Adsorption capacities of carbons modified with $CH_3COOH$, $H_3PO_4$, and $H_2SO_4$ increased up to 3.34, 21.00, and 35.21 mg $NH_3/g$, respectively. Those of carbons with Cu, Zn, Zr, Fe, and Sn were 9.63, 9.13, 7.09, 25.12 and 15.03 mg $NH_3/g$. Ammonia adsorption was enhanced by the presence of surface oxygen groups on carbon materials, which influenced pH of carbon surface. BET surface area of raw carbon was analyzed to be $1087m^2/g$, but it decreased by carbon surface modification. Fe-impregnated carbon showed $503.02m^2/g$ of surface area. These observations were mostly caused by chemical adsorption.

• Proceedings of the KOSOMBE Conference
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• v.1997 no.11
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• pp.365-368
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• 1997

We are developing a small gamma camera or imaging malignant breast tumors. The small scintillation camera system consists of NaI(Tl) crystal ($60\;{\times}\;60\;{\times}\;6\;mm^3$) coupled to position sensitive photomultiplier tube (PSPMT), nuclear instrument module (NIM), analog to digital converter (ADC), and personal computer. High quality flood source image and hole mask image were obtained using the gamma camera developed in this study. Breast phantom containing $2{\sim}7\;mm$ diameter spheres was successfully imaged with parallel hole collimator. The obtained image displayed accurate activity distribution over the imaging field of view. Linearity and uniformity correction algorithms are being developed. It is believed that the developed small gamma camera could be useful or detection of malignant breast cancer.

• The Korean Journal of Food And Nutrition
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• v.23 no.3
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• pp.419-427
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• 2010

The focus of the current study was to investigate the physicochemical properties of a corn starch-sponge matrix prepared at a low concentration below gel forming by freeze-drying. The effect of variables(starch concentration, heating temperature, and heating hold time) on the physicochemical properties of the samples was analyzed by response-surface methodology. Regression models on the properties of samples such as hardness, springiness, and water solubility index(WSI) showed high correlation coefficients(r>0.95) and significant F values, but regression models for the other properties(swelling power, apparent viscosity, reducing sugar content, and digestibility) showed them to have relatively low significance. Sample hardness of sample showed the highest value at condition of $90^{\circ}C$ and 5%, whereas springiness was at a maximum at $130^{\circ}C$ and 5%. Also, at 1% of starch concentration, mechanical properties were greatly decreased as the relative humidity increased, compared with the 3% and 5%, especially in the hardness of samples. The WSI showed an increasing trend with heating temperature regardless of starch concentration. Overall, the physicochemical properties of freeze-dried corn starch-sponge matrix were influenced much more by starch concentration and heating temperature than by heating hold time. The results of this study show that the basic properties of freeze-dried corn starch-sponge matrix can be used for the specific food applications or as a functional material for its stability.

• Journal of Hospice and Palliative Care
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• v.24 no.2
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• pp.116-129
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• 2021

Purpose: The purpose of this study was to examine the knowledge, caregiving performance, stress levels, and mental health of family caregivers of terminal cancer patients with delirium, insofar as these characteristics are relevant for delirium. Methods: Between May 1, 2019, and June 1, 2020, 96 family caregivers of terminal cancer patients with delirium completed a structured survey, the results of which were analyzed. Results: The average correct answer rate for delirium-related knowledge was 53.2% across all subcategories, which included knowledge of causes (41.5%), symptoms (65.4%), and caregiving (51.7%). The average score for family caregivers' performance of caregiving for delirium was 2.60±0.5, with subcategories including caregiving for patients without delirium (2.16±0.95), caregiving for patients with delirium (2.84±1.01), and stress related to caregiving for delirium (39.88±16.55), as well as categories such as patient-related caregiving (44.32±28.98), duty-related caregiving (44.21±30.15), and interpersonal relationship-related caregiving (22.35±25.03). For mental health, the average score among family caregivers was 1.96±0.70, with the highest score being for the category of additional items (2.28±0.84). Family caregivers of patients with hyperactive delirium as the delirium subtype had higher scores for caregiving performance than caregivers of patients with mixed delirium. Conclusion: Scores for the delirium-related knowledge and caregiving performance of family caregivers were low, while their caregiving stress levels were high due to their lack of knowledge and experience. This indicates the importance of delirium-related education for family members of patients with delirium and the necessity of developing nursing intervention programs to help manage stress and promote mental health among family caregivers.

• JSTS:Journal of Semiconductor Technology and Science
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• v.16 no.2
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• pp.166-171
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• 2016

Nickel silicide is main issue in Polycrystalline silicon Thin Film Transistor (TFT) which is made by Metal Induced Lateral Crystallization (MILC) method. This Nickel silicide acts as a defect center, and this defect is one of the biggest reason of the high leakage current. In this research, we fabricated polycrystalline TFTs with novel method called Edge Cut (EC). With this new fabrication method, we assumed that nickel silicide at the edge of the channel region is reduced. Electrical properties are measured and trap state density also calculated using Levinson & Proano method.

• Annual Conference of KIPS
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• 2016.10a
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• pp.309-312
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• 2016

Green Internet of Things (IoT) is the study and practice of eco-friendly sustainable computing. The basic goal of green computing is to reduce the use of materials and maximize energy efficiency with reliable and secure communications. The paper presents various technologies and issues regarding green IoT. It also studies the green Information and Communication Technology (ICT) such as green M2M, green Cloud Computing (CC), and green Data Center (DC). In addition, this paper mentions about the reliability in IoT Communication and and issues to achieve green IoT communication by applying efficient activity scheduling technique for energy saving. Finally, we propose the green IoT-Home Service (GIHS) model which provides efficient energy management in home automation system.

• Proceedings of The Korean Society of Agricultural and Forest Meteorology Conference
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• 2017.11a
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• pp.36-37
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• 2017

• Korean Journal of Community Nutrition
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• v.10 no.4
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• pp.462-470
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• 2005

The purpose of this study was to determine the characteristics of infants' temperaments, maternal feeding behaviors and feeding practices in picky eaters. Participants were 83 infants (aged 12 - 24 months) from 'A' hospital (Seoul) and 'B' public health center (Kyunggido). Mothers completed questionnaires that assessed their own feeding behavior, feeding practices, infants' temperament and infants' feeding behavior. Picky eaters' demographics were not significantly different from non-picky eaters after adjusting sex and age. The average of thiamin, niacin and vitamin E intakes of picky eaters were below $75\%$ Korean RDA, whereas vitamin A intakes exceed $120\%$ RDA in both groups. Activity level of infants' temperament and disinhibition of maternal feeding behavior in picky eaters were significantly higher than those in non-picky eater. All constructs of infants feeding behavior were significantly associated with certain constructs of infants' temperament, maternal feeding practice and maternal feeding behavior. The pickiness of infants feeding behavior was positively correlated with activity level of infants' temperament, pickiness and disinhibition of maternal feeding behavior and negatively correlated with adaptability of infants' temperament. Findings suggest that maternal feeding behavior and feeding practices as well as infants' temperament should be addressed in nutrition education for picky eaters.

• Korean Journal of Veterinary Research
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• v.39 no.3
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• pp.665-671
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• 1999

The aim of this study was to establish selective hepatic artery catheterization technique through percutaneous femoral artery puncture and to offer digital subtraction angiography (DSA) of hepatic artery in beagle dogs. Percutaneous femoral artery puncture was performed with Sheldinger's method. Microferret$^{TM}$-18 Infusion catheter(William, Cook, Europe) was introduced into abdominal aorta. Then, under fluoroscopy, iopamidol 370(Bracco, Italy) was injected to identify celiac artery and 'J' shaped guide wire was introduced into celiac artery. Catheter could be introduced into celiac artery through guide wire. In this manner, catheter was located at the insertion of hepatic artery and DSA was performed. In DSA of beagle dogs, hepatic artery which was divided into lateral branch, right-medial branch, right-lateral branch of hepatic artery, cystic artery and gastroduodenal artery was opacified without superimposition of any other body structure and so was the parenchyme of liver afterward. In autopsy angiographic finding of resected liver, cystic artery, caudate branch, lateral branch, right-medial branch, right-lateral branch and quadrate branch of hepatic artery were identified. It was concluded that selective hepatic artery catheterization technique was a minimally invasive method that facillitated the approach of hepatic artery and DSA was an excellent tool to visualize the vessle of liver in dogs.