• Title/Summary/Keyword: center in Seoul

Search Result 11,609, Processing Time 0.113 seconds

Intensive Monitoring Survey of Nearby Galaxies (IMSNG) : On the progenitor system of Type Ia SN 2018kp

  • Choi, Changsu;Im, Myungshin;Kim, Dohyeong;Lim, Gu;Paek, Gregory S.H.;Kim, Sophia;Hwang, Sungyong
    • The Bulletin of The Korean Astronomical Society
    • /
    • v.45 no.1
    • /
    • pp.36.2-36.2
    • /
    • 2020

  • Intensive Monitoring Survey of Nearby Galaxies (IMSNG) has been managed over 6 years. It aimed to constrain the progenitor system and explosion mechanism of SNe by detection of very early signal from shock heated emission. We have conducted monitoring observation of nearby bright galaxies those were carefully selected using global network of 1-m class telescopes. More than 20 SNe have occured in our target fields. As One of result of the survey, we present light curve analysis of type Ia SN 2018kp, which was discovered in NGC 3367. Based on photometric analysis, we calculated explosion parameters and set constraints of physical conditions of this supernova. We compared the results with theoretical model progenitor systems to find out which scenario is the most fitted to SN 2018kp case. Moreover, we estimate the distance to the galaxy and look into the relation between SNe and galactic physical parameters.

  • PDF

Prasugrel-based De-Escalation of Dual Antiplatelet Therapy After Percutaneous Coronary Intervention in Patients With STEMI

  • You-Jeong Ki;Bong Ki Lee;Kyung Woo Park;Jang-Whan Bae;Doyeon Hwang;Jeehoon Kang;Jung-Kyu Han;Han-Mo Yang;Hyun-Jae Kang;Bon-Kwon Koo;Dong-Bin Kim;In-Ho Chae;Keon-Woong Moon;Hyun Woong Park;Ki-Bum Won;Dong Woon Jeon;Kyoo-Rok Han;Si Wan Choi;Jae Kean Ryu;Myung Ho Jeong;Kwang Soo Cha;Hyo-Soo Kim;HOST-RP-ACS investigators
    • Korean Circulation Journal
    • /
    • v.52 no.4
    • /
    • pp.304-319
    • /
    • 2022

  • Background and Objectives: De-escalation of dual-antiplatelet therapy through dose reduction of prasugrel improved net adverse clinical events (NACEs) after acute coronary syndrome (ACS), mainly through the reduction of bleeding without an increase in ischemic outcomes. Whether the benefits of de-escalation are sustained in highly thrombotic conditions such as ST-elevation myocardial infarction (STEMI) is unknown. We aimed to assess the efficacy and safety of de-escalation therapy in patients with STEMI or non-ST-segment elevation ACS (NSTE-ACS). Methods: This is a pre-specified subgroup analysis of the HOST-REDUCE-POLYTECH-ACS trial. ACS patients were randomized to prasugrel de-escalation (5 mg daily) or conventional dose (10 mg daily) at 1-month post-percutaneous coronary intervention. The primary endpoint was a NACE, defined as a composite of all-cause death, non-fatal myocardial infarction, stent thrombosis, clinically driven revascularization, stroke, and bleeding events of grade ≥2 Bleeding Academic Research Consortium (BARC) criteria at 1 year. Results: Among 2,338 patients included in the randomization, 326 patients were diagnosed with STEMI. In patients with NSTE-ACS, the risk of the primary endpoint was significantly reduced with de-escalation (hazard ratio [HR], 0.65; 95% confidence interval [CI], 0.48-0.89; p=0.006 for de-escalation vs. conventional), mainly driven by a reduced bleeding. However, in those with STEMI, there was no difference in the occurrence of the primary outcome (HR, 1.04; 95% CI, 0.48-2.26; p=0.915; p for interaction=0.271). Conclusions: Prasugrel dose de-escalation reduced the rate of NACE and bleeding, without increasing the rate of ischemic events in NSTE-ACS patients but not in STEMI patients.

  • https://doi.org/10.4070/kcj.2021.0293 인용 PDF

The Methods for Foot Function Index and Foot and Ankle Outcome Score Measurement: A Comparison between Paper-and-Pencil Method and Electronic Method (Foot Function Index와 Foot and Ankle Outcome Score의 기입방법 연구: 종이와 연필을 이용한 기입 방법과 전자기기를 이용한 두 가지 측정방법에 대한 일치도 비교)

  • Kim, Ji-Beom;Kwon, Min-Soo;Kim, Jung-Gon;Yi, Young;Lee, Woo-Chun;Ha, Jeong-Ku;Jang, Suk-Hwan
    • Journal of Korean Foot and Ankle Society
    • /
    • v.21 no.1
    • /
    • pp.33-38
    • /
    • 2017

  • Purpose: The patient-reported outcome measure (PROM) is used to quantify the subjective state of patients before and after the treatment. The electronic method was recently developed and used for the completion of PROM, in addition to the conventional paper and pencil method. This study identified whether the results of Foot Function Index (FFI) and Foot and Ankle Outcome Score (FAOS) using the paper and pencil method was different from those using the electronic method. Materials and Methods: Between May 2016 and August 2016, 42 patients who were admitted to the Seoul Foot and Ankle Center two days before surgery were included for evaluation. The mean age was 46 years (range, 21~72 years). There were 29 males and 13 females. To use the electronic method, the PADAS software (PADAS, Seoul, Korea) was implemented using a touch pad. The primary trial of FFI and FAOS was performed using either the paper-and-pencil method or the electronic method. At 24 hours after the primary test, a secondary trial of FFI and FAOS was performed using the other method. Then, we identified the reliability of FFI and FAOS between the two methods by calculating the intraclass coefficient. Results: Twenty-two patients underwent the first trial using the paper-and-pencil method, and 20 patients underwent the first trial using the electronic method. Of the 42 patients, 8 patients were excluded from this study and only 34 patients were included in this study. The reliability of FFI was excellent with an intraclass coefficient of 0.957, and the reliability of FAOS was also excellent with an intraclass coefficient of 0.840. Conclusion: The paper-and-pencil method and the electronic method have the same result for the completion of FFI and FAOS in this study. Therefore, it is commonly considered that the completion of FFI and FAOS using the electronic method can be applied in practice.

  • https://doi.org/10.14193/jkfas.2017.21.1.33 인용 PDF