• Journal of the Korean earth science society
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• v.30 no.2
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• pp.153-164
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• 2009

We examined the regional 1-D deep resistivity structure of the Korean Peninsula using MT data acquired at seven sites located in the Kyongsang Basin and Kyonggi Massif. At the sites located in the Kyongsang Basin, surrounding sea distorts observed MT response and hence this distortion, so called "sea effect", is corrected using an iterative tensor stripping method. The 1-D layered inversion results for the seven MT sites reveal 4 layered structure, which is composed of 1) near surface layer, 2) upper crust, 3) lower crust and upper mantle, and 4) asthenosphere from the surface downward. Conrad interface, which is a boundary between upper and lower crust, is distinctly identified beneath all the MT sites. Conrad interface depth is estimated to about be 17km in the Kyongsang Basin and about 12km in the Kyonggi Massif, while the upper crust of the Kyongsang Basin is about 5 times more resistive than that of the Kyonggi Massif. Finally, asthenosphere is inferred to exist below a depth of approximately 100km with a resistivity of 200-300 ohm-m.

• Korean Journal of Community Nutrition
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• v.13 no.4
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• pp.582-591
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• 2008

Both genetic and environmental factors play important roles in the pathogenesis of Parkinson Disease(PD). The contribution of many environmental factors including dietary factor remains unproven. The purpose the study was to investigate the dietary habits, nutrient intake and dietary quality of Korean PD patients according to the duration of disease. PD patients were recruited from K and S university hospitals from May 2005 to January 2006. This study was carried out after approval by the Institute Review Board(IRB). British Brain Bank criteria was used to diagnose PD. The subjects were classified into 2 groups based on the duration of PD: <25 months and $\geq$25 months groups. General characteristics, anthropometric measurements, food habits and dietary intakes were investigated. The results of this study were as follows: 1) The mean age of <25 months group($66.9{\pm}8.0$ yr) was significantly higher than that of $\geq$25 months group($62.2{\pm}8.8$ yr)(p<0.05). No significant differences were found for academic background, occupation, living status and social activity, however, numbers of diseases, exercise and family history of PD were significantly different. 2) Anthropometric measurements were not different between the two groups. 3) The frequency of taking snacks was significantly higher in <25 months group and the amounts of alcohol consumption were significantly higher in $\geq$25 months group. 4) Daily intakes of most nutrients were very low compared with DRI. 5) The MAR score was significantly lower in <25 months group(p<0.05;) however, the scores of DVS, DDS and DQI were not significantly different. As a conclusion an overall nutrient intake and dietary quality of the Parkinson's Disease patients need to be improved regardless of duration of the disease and a well-balanced diet should be emphasized.

• The Korean Journal of Physiology and Pharmacology
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• v.20 no.5
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• pp.459-466
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• 2016

Adipogenic differentiation of mesenchymal stem cells (MSCs) is critical for metabolic homeostasis and nutrient signaling during development. However, limited information is available on the pivotal modulators of adipogenic differentiation of MSCs. Adaptor protein Lnk (Src homology 2B3 [SH2B3]), which belongs to a family of SH2-containing proteins, modulates the bioactivities of different stem cells, including hematopoietic stem cells and endothelial progenitor cells. In this study, we investigated whether an interaction between insulin-like growth factor-1 receptor (IGF-1R) and Lnk regulated IGF-1-induced adipogenic differentiation of MSCs. We found that wild-type MSCs showed greater adipogenic differentiation potential than $Lnk^{-/-}$ MSCs. An ex vivo adipogenic differentiation assay showed that $Lnk^{-/-}$ MSCs had decreased adipogenic differentiation potential compared with wild-type MSCs. Interestingly, we found that Lnk formed a complex with IGF-1R and that IGF-1 induced the dissociation of this complex. In addition, we observed that IGF-1-induced increase in the phosphorylation of Akt and mammalian target of rapamycin was triggered by the dissociation of the IGF-1R-Lnk complex. Expression levels of a pivotal transcription factor peroxisome proliferator-activated receptor gamma ($PPAR-{\gamma}$) and its adipogenic target genes (LPL and FABP4) significantly decreased in $Lnk^{-/-}$ MSCs. These results suggested that Lnk adaptor protein regulated the adipogenesis of MSCs through the $IGF-1/Akt/PPAR-{\gamma}$ pathway.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.2
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• pp.277-286
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• 2017

This study assesses the association of nurses' hope, grateful disposition, and workplace spirituality with the goals of providing human resource management plans that lead to efficient and competitive nurse structure by building a nurse organizational culture based on analyzing the influences affecting organizational citizenship behavior. Participants were 147 nurses working in four general hospitals in Seoul and Gyeonggi-do. The survey data were analyzed by frequencies, t-test, ANOVA, Pearson correlation coefficients and multiple stepwise regression via SPSS WIN 18.0. Results showed that organizational citizenship behavior is positively associated with nurse's hope (${\gamma}=.22{\sim}.36$, p<.001), grateful disposition (${\gamma}=.38$, p<.001) and workplace spirituality (${\gamma}=.38{\sim}.54$, p<.001). The significant predictors of organizational citizenship behavior were workplace spirituality (${\beta}=.54$, p<.001), hope of turnover (${\beta}=.12$, p<.001), hope (${\beta}=.09$, p<.001) and grateful disposition (${\beta}=.08$, p<.001), which explained 41.6% of the variance in organizational citizenship behavior. This study systematizes a theory for workplace spirituality processing the early stage research in nurse structure. To improve organizational citizenship behavior among nurses, educational programs and supporting systems should be developed to increase nurses' hope, disposition of grateful disposition, and workplace spirituality.

• Korean Journal of Soil Science and Fertilizer
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• v.33 no.1
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• pp.32-39
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• 2000

To investigate the adsorption-desorption reaction of Cd by sewage sludge, the adsorption of Cd from $Cd(NO_3)_2$ solutions of concentrations ranging from 5 to $50{\mu}g\;Cd\;mL^{-1}$ by sewage sludge was examined for reaction periods up to 48 hours. The amount of Cd adsorbed as a function of time was measured. The adsorption between Cd in solution and the solid phase could be described by two stages. The initial adsorption of Cd was very rapid, that is, approximately 95% of the added Cd was removed from solution within the first 30 minutes. Further, the greater the concentration of Cd added, the greater was the amount of Cd adsorbed. After the rapid initial decrease of Cd, a slower decline in the Cd concentration resulted which followed first order reversible kinetics. The equilibrium concentrations for the reactions, as well as the time period for the equilibrium reactions were dependent on the initial Cd concentrations. If equilibrium is reached, the amount of Cd remaining in solution is greater when the amount adsorbed is higher, although the percentage of Cd in solution is constant relative to the initial concentration of Cd. Some of the adsorbed Cd was released back to solution since the concentration of Cd after 48 hours was higher than the equilibrium concentration of Cd. However, despite the increased amount of Cd measured, the overall net reaction was a significant adsorption of Cd from solution by sewage sludge.

• Korean Journal of Microbiology
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• v.34 no.4
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• pp.188-193
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• 1998

The authors examined the variations of environmental factors, the distributions of cyanobacteria, heterotrophic bacteria, and microorganisms that inhibit the growth of Anabaena cylindrica according to development and extinction of cyanobacterial bloom at a site in Daechung Dam reservoir. And certified the relationship between each other. Water temperature variated in a typical pattern. pH and concentrations of dissolved oxygen and chlorophylla was high in bloom period, and lowered with the decline of bloom. Phosphorus played as a growth-limiting factor at this study site. Total nitrogen concentration increased during blooming period, which indicated that nitrogen has been fixed by aquatic organisms such as cyanobacteria. Cyanobacteria distributed from June 17, and such cyanobacterial species as Anabaena spp., Aphanizomenon spp., Microcystis spp., Oscillatoria spp. and Phormidium spp. was detected during study period. Anabaena spp. distributed relatively highly distributed from July 23 to September 22, and disappeared completely at September 29. Heterotrophic bacterial and cyanobacterial populations varied inverse-proportionally. There was a relevancy between the variations of Anabaena spp., heterotrophic bacteria, and microorganisms that inhibit the growth of Anabaena cylindrica. Microorganisms that inhibit the growth of Anabaena cylindrica distributed from early growth phase of Anabaena spp. population to immediately after the extinction of Anabaena spp. With the population of Anabaena cylindrica growth-inhibiting microorganisms decreasing, increases of heterotrophic bacterial population followed it. Thease results indicate that microorganisms have a part in the extinction of cyanobacterial bloom, especially at its destroying period.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.32 no.4
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• pp.444-451
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• 1999

The effect of individual density on the growth and survival of Laminaria japonica was experimentally evaluated. Four density treatments of young sporophytes (0.63 cm In maximum length) grown in the laboratory were transplanted to the southeastern coast of Korea and their survivorship and growth rate were measured twice a month from January to July, 1996. Plants showed higher survivorship at low density. Final densities at three lowest densities were similar, ranging from 34 to 38 inds${\cdot}100 cm^{-2}$. Planis at the highest density, however, suffered greater decline than at lower densities, and only 21 plants remained at the end of this study. Mean frond size (length and width) fluctuated throughout the study period at four densities. During the first two mouths after outplanting, mean frond size was negatively correlated with initial density, However, the size was density independent after three months. As stand density increased, size-frequency distribution through time tended to be more positively skewed. The 10 largest plants grew faster in frond size and attained larger size in the lower density. There was a positive relationship between plant size and relative growth rate (or survival). The slope of yield-density (Y-D) relationships at four densities ranged from -0.060 to -0.137. The study suggests that density can strongly affect the survival and growth of this alga. The density-dependent survival and growth patterns, however, were not strictly consistent with those of terrestrial plants.

• Anxiety and mood
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• v.14 no.2
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• pp.53-62
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• 2018

Objective : The Korean Association of Anxiety Disorders developed Korean guidelines for treatment of panic disorder (PD) 2018. In this paper, we discussed the consensus among psychiatrists, regarding initial and maintenance treatment strategies for pharmacological treatment of PD in Korea. Methods : Based on current treatment guidelines published by the American Psychiatric Association, the National Institute for Clinical Excellence, and the Canadian Psychiatric Association, we developed questionnaires pertinent to initial and maintenance treatment strategies for pharmacological treatment of PD. Seventy-two experts in PD answered questionnaires. We classified expert opinions into three categories, first, second, and third-line treatment strategies, by analyzing the 95% confidence interval. Results : Antidepressants, benzodiazepine anxiolytics, and cognitive-behavioral therapy (CBT) were recommended as treatments of choice (ToC), and first-line strategies for initial treatment of PD. Escitalopram, paroxetine, sertraline, and venlafaxine were preferred from among many anti-panic drugs. Mean starting dose of anti-panic drugs for initial treatment of PD was relatively lower, than that for other psychiatric illnesses such as major depressive disorder. In the case of maintenance treatment of PD, antidepressants and CBT were selected as ToC and first-line strategies. Patients were typically examined every four weeks during treatment, to review effectiveness and side effects of the drug. Pharmacotherapy was generally continued for one year or more. Conclusion : This study provides information about consensus among Korean experts regarding pharmacological treatment strategies for patients with panic disorder.

• Journal of the Korean Geotechnical Society
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• v.37 no.9
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• pp.5-12
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• 2021

Pseudo-static slope stability analysis method is widely used in engineering practice to calculate the seismic factor of safety of slope subjected to earthquake ground motions. Although the dynamic analysis method is well recognized to have the primary advantage of simulating the stress-strain response of soils, it is not often used in practice because of the difficult in estimating the factor of safety. In this study, a procedure which utilizes the dynamic analysis method to extract the transient dynamic factor of safety is devleoped. This method overcomes the major limitation of the pseudo-static method, which uses an empirically determined seismic coefficient to derive the factor of safety. The proposed method is applied to a slope model and the result is compared with that of the pseudo-static method. It is shown that minimum dynamic factor of safety calculated by the dynamic analysis is slightly larger than that determined from the pseudo-static method. It is also demonstrated that the dynamic factor of safety becomes minimum when the horizontal seismic coefficient and horizontal average acceleration are maximum.

• Korean Journal of Social Welfare Studies
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• v.48 no.3
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• pp.83-116
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• 2017

The purpose of this study is to raise the issue of the existing deinstitutionalization debate, considering only the shipment process to these two spaces, and still leaving the inter-facility circulation of vulnerable mental handicapped who are still hanging around the facility. In particular, we sought to supplement the discussion of deinstitutionalization by illuminating the problems of those who have to rely on facilities, as well as the mental health facility system and the homeless facility system. In the case of homeless persons with mental disabilities who repeatedly use the mental health facility system and the homeless facility system, they confirmed the pattern of using the facilities by constantly changing the place to manage the overlapping risk of mental illness and homelessness. Also it is triggered by the voluntary nature of the parties with no resources and resources. This situation appeared to be inevitable in the absence of resources and supportive systems that would actually enable a life in the community. Nevertheless, I asserted that the life of the mentally handicapped, which is circling the facility, is extremely unstable and is not desirable from a welfare point of view.