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Depression and Risk Factors in Patients with Crohn's Disease (크론병 환자의 우울과 위험요인)

  • Cho, Ok-Hee;Yoo, Yang-Sook;Yang, Suk-Kyun
    • Journal of Korean Academy of Nursing
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    • v.42 no.2
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    • pp.207-216
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    • 2012
  • Purpose: This study was conducted to determine the risk factors among patients with depression with Crohn's disease. Methods: Data were collected by questionnaire from 276 patients who were diagnosed with Crohn's disease at a tertiary hospital located in Seoul. Measurements included patients' demographic characteristics, clinical characteristics, depression level, and health-related quality of life. Data were analyzed using t-test, $X^2$-test, Wilcoxon rank sum test, and logistic regression analyses. Results: The incidence rate of depression (BDI-II${\geq}$14scores) was 31.9% (n=88). Univariate analysis revealed that being a woman, school graduation status, economic status (low), BMI(<$18.5Kg/m^2$), disease duration (${\geq}3$ years), CDAI (${\geq}150$ scores), frequency of hospital admission (${\geq}2$), extra-intestinal manifestation (arthralgia, stomatitis), administration of 5-aminosalicylic acid, and disease related quality of life (SIBDQ<50 scores) were associated with depression. Multivariate analysis revealed that economic status (low), school graduation status, and quality of life (SIBDQ<50 scores) were more likely to report high level of depression. Conclusion: Future research should consider managing depression as an essential component of comprehensive care for patients with Crohn's disease. In addition, further research is needed to develop strategies to better improve quality of life among patients with Crohn's disease who are depressed.

A Review on Dynamic Changes of Consumer's Attributes and Marketing Mix Strategies of Cut Roses in Korea (장미에 대한 선호속성의 동태적 변화와 마케팅 믹스전략 탐색)

  • Kim, Bae-Sung
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.12 no.10
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    • pp.4328-4336
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    • 2011
  • The aim of this study is to find changes of the attributes that influence the purchase of cut roses during recent five years(2007~2011) and suggest some implications on ways to promote cut roses marketing. For this purpose, a survey was conducted through the Internet among 1,100 randomly chosen people living in Seoul, Inchon and Gyeonggi Province in 2011. A total of 1,023 valid replies were received for the analysis of the survey which was carried out by the subsidiary consulting firm. The survey panels and estimation models to analyze changes of consumers' preference attributes during recent five years are same to them of Kim, et al.(2007). That is, empirical analysis tools such as ordered probit model, multinomial logit model, and conjoint analysis were used according to Kim, et al.(2007). This paper suggests several policy implications to set up the target market of cut roses and marketing mix strategy to specify the best 4P(product, price, place and promotion).

Recurrent macrophage activation syndrome since toddler age in an adolescent boy with HLA B27 positive juvenile ankylosing spondylitis

  • Park, Joon Hyeong;Seo, Yu Mi;Han, Seung Beom;Kim, Ki Hwan;Rhim, Jung Woo;Chung, Nack Gyun;Kim, Myung Shin;Kang, Jin Han;Jeong, Dae Chul
    • Clinical and Experimental Pediatrics
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    • v.59 no.10
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    • pp.421-424
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    • 2016
  • Recurrent macrophage activation syndrome (MAS) is very rare. We present the case of an adolescent boy with human leukocyte antigen (HLA) B27-positive ankylosing spondylitis (AS), who experienced episodes of recurrent MAS since he was a toddler. A 16-year-old boy was admitted because of remittent fever with pancytopenia and splenomegaly after surgical intervention for an intractable perianal abscess. He had been diagnosed with hemophagocytic lymphohistiocytosis (HLH) 4 different times, which was well controlled with intravenous immunoglobulin and steroids since the age of 3. We were unable to identify the cause for the HLH. He remained symptom-free until the development of back pain and right ankle joint pain with swelling at 15 years of age. He was diagnosed with HLA B27-positive AS with bilateral active sacroiliitis. He showed symptom aggravation despite taking naproxen and methotrexate, and the symptoms improved with etanercept. On admission, his laboratory data showed leukopenia with high ferritin and triglyceride levels. Bone marrow biopsy examination showed histiocytic hyperplasia with hemophagocytosis. There was no evidence of infection. He received naproxen alone, and his symptoms and laboratory data improved without any other immunomodulatory medications. Genetic study revealed no primary HLH or inflammasome abnormalities. In this case, underlying autoimmune disease should have been considered as the cause of recurrent MAS in the young patient once primary HLH was excluded.

Factors Influencing the Quality of Life of Stroke Patients : A Systematic Review (뇌졸중 환자의 삶의 질에 영향을 끼치는 요인: 체계적 문헌고찰)

  • Jung, Jun-Sik
    • Therapeutic Science for Rehabilitation
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    • v.4 no.1
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    • pp.39-51
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    • 2015
  • Objective : To synthesize and identify the studies that delineated the relationship between quality of life and other factors in stroke patients in South Korea. Method : Electronic databases were searched, including KISS, NDSL, National Assembly Library and KmBase. The search terms included stroke, quality of life and correlation, relationship. Only papers published in Korean were included. Results : Twelve studies, from 256 references screened, were included. All studies were non-experimental and correlational analysis. A correlation coefficient between Quality of Life and ADL .293~.622, Depression -.804~-.533, Cognition .090~.610, Quality of Sleep .107, Quality of Satisfaction .367, Fatigue -.260, MAL(Quality of Movement .208, Amount of Use .364), Family Support .824, Pain -.306, Motivation for Rehabilitation .51~.86, Balance .740, Self-efficacy .388 were analyzed respectively. Conclusion : The quality of life of stroke patients was influenced by multiple factors. Occupational therapists need to consider the functions of upper extremity and activities of daily living as well as depression, cognition, sleep, family support, pain, and self efficacy to improve quality of life of stroke patients.

Investigation of Cooling Performance of Injection Molds Using Pulsed Mold Temperature Control (가변 금형온도 제어기법을 적용한 사출금형의 냉각성능 고찰)

  • Sohn, Dong Hwi;Park, Keun
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.37 no.1
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    • pp.35-41
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    • 2013
  • In injection molding, the mold temperature is one of most important process parameters that affect the flow characteristics and part deformation. The mold temperature usually varies periodically owing to the effects of the hot polymer melt and the cold coolant as the molding cycle repeats. In this study, a pulsed mold temperature control was proposed to improve the part quality as well as the productivity by alternatively circulating hot water and cold water before and after the molding stage, respectively. Transient thermal-fluid coupled analyses were performed to investigate the heat transfer characteristics of the proposed pulsed mold heating and cooling system. The simulation results were then compared with those of the conventional mold cooling system in terms of the heating and cooling efficiencies of the proposed pulsed mold temperature control system.

Structural Analysis of the fcbABC Gene Cluster Responsible for Hydrolytic Dechlorination of 4-Chlorobenzoate from pJS1 Plasmid of Comamonas sp. P08

  • Lee, Jeong-Soon;Lee, Kyoung;Ka, Jong-Ok;Jong-Chan;Kim, Chi-Kyung
    • Journal of Microbiology
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    • v.41 no.2
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    • pp.89-94
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    • 2003
  • Bacterial strain No. P08 isolated from wastewater at the Cheongju industrial complex was found to be capable of degrading 4-chlorobenzoate under aerobic condition. P08 was identified as Comamonas sp. from its cellular fatty acid composition and 16S rDNA sequence. The fcb genes, responsible for the hydrolytic dechlorination of 4-chlorobenzoate, were cloned from the plasmid pJJl of Comamonas sp. P08. The fcb gene cluster of comamonas sp. PO8 was organized in the order fcbB-fcbA-fcbTl-fcbT2-fcbT3-fcbC. This organization of the fcb genes was very similar to that of the fcb genes carried on the chromosomal DNA of pseudomonas sp. DJ-12. However, it differed from the fcbA-fcbB -fcbC ordering of Arthrobacter sp. SU. The nucleotide sequences of the fcbABC genes of strain P08 showed 98% and 53% identities to those of Pseudomonas sp. DJ-12 and Arthrobacter sp. SU, respectively. This suggests that the fcb genes might have been derived from Pseudomonas sp. DJ-12 to form plasmid pJSl in Comamonas sp. P08, or that the fcb genes in strain DJ-12 were transposed from Comamonas sp. P08 plasmid.

Microstructure Characterization of Nb-Si-B alloys Prepared by Spark Plasma Sintering Process (방전 플라즈마 소결(Spark Plasma Sintering) 방법에 의해 제조된 Nb-Si-B계 합금의 미세조직 특성)

  • Kim, Sang-Hwan;Kim, Nam-Woo;Jeong, Young-Keun;Oh, Sung-Tag;Kim, Young Do;Lee, Seong;Suk, Myung Jin
    • Journal of Powder Materials
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    • v.22 no.6
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    • pp.426-431
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    • 2015
  • Microstructural examination of the Nb-Si-B alloys at Nb-rich compositions is performed. The Nb-rich corner of the Nb-Si-B system is favorable in that the constituent phases are Nb (ductile and tough phase with high melting temperature) and $T_2$ phase (very hard intermetallic compound with favorable oxidation resistance) which are good combination for high temperature structural materials. The samples containing compositions near Nb-rich corner of the Nb-Si-B ternary system are prepared by spark plasma sintering (SPS) process using $T_2$ and Nb powders. $T_2$ bulk phase is made in arc furnace by melting the Nb slug and the Si-B powder compact. The $T_2$ bulk phase was subsequently ball-milled to powders. SPS is performed at $1300^{\circ}C$ and $1400^{\circ}C$, depending on the composition, under 30 MPa for 600s, to produce disc-shaped specimen with 15 mm in diameter and 3 mm high. Hardness tests (Rockwell A-scale and micro Vickers) are carried out to estimate the mechanical property.

Analysis of Pulse Waveform and Pulse Wave Velocity of Carotid Artery and Radial Artery by Using Clip-type Pulsimeter Equipped with Permanent and Hall Device (영구자석과 홀소자가 구비된 맥진기를 이용한 경동맥과 요골동맥의 맥진파형과 맥파전달속도 분석)

  • Kim, Dong-Young;Lee, Sang-Suk;Hyeon, Seog-San;Rhee, Jin-Kyu
    • Journal of the Korean Magnetics Society
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    • v.24 no.5
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    • pp.146-151
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    • 2014
  • The pulse waveforms of a carotid artery in the neck and a radial artery in the hand wrist were individually measured by using clip-type pulsimeter equipped with a permanent and Hall device. The pulse transit time and the pulse wave velocity obtained through comparison of two pulse waveforms were analyzed each other. A value of the pulse wave velocity was about 8.5 m/s similar to one measured by a conservative method. This result suggests that the clip-type pulsimeter as the reproducible and reliable one oriental diagnostic medical device can be predicted to any atherosclerosis state in the cardiac circulatory system.

Study on the Effects of Work-Family Spillover among Married Individuals: Focusing on the Moderating Effects of the Use of HFSC (기혼자의 일-가족 전이에 미치는 영향 연구: 건강가정지원센터 이용유무에 따른 조절효과 중심으로)

  • Chang, Jinkyung;Jun, Jongmi
    • Journal of Families and Better Life
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    • v.33 no.4
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    • pp.1-17
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    • 2015
  • The purpose of this study was to investigate the effects of individual characteristics, family characteristics, job characteristics, and family strength on work-family spillover in dual-earner families focusing on users and non-user of Healthy Family Support Centers(HFSC). The subjects were 703 people who lived in Seoul and Gyeonggi-Do. The results were analyzed by using the PASW 21.0 program. The findings of this study led to the following conclusions: First, the users of HFSC showed a higher level of family strength than the non-users did. This is the users had a high level of awareness of family's values and importance compared to the non-users. Second, the users revealed higher levels at a positive spillover from work to family and from family to work than the non-users. Therefore, it is confirmed that the users have a positive view of work-family spillover due to their family strength. Finally, there was a significant result at the moderation effects of work-family spillover according to personal traits, family and job characteristics. Specifically, work-family negative spillover was effected family strength through the age of the users' children. The result suggest that family strength has positive effects on the family cycle. It will be worthwhile to pay attention in future research to discover what is the appropriate support for dual earner families.

Structural Relationships among 4- to 5- Year-Old Children's Playfulness, Communication Skills, and Creative Characteristics (만 4, 5세 유아의 놀이성과 의사소통 능력 및 창의적 행동특성 간의 구조적 관계)

  • Chung, Mi Ra;Kang, Su Kyoung;Kim, Min Jeong
    • Human Ecology Research
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    • v.53 no.5
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    • pp.531-542
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    • 2015
  • This study examined the structural relationships among 4- and 5-year-old children's playfulness, communication skills, and creative characteristics. This research analyzed the direct and indirect influence of child's playfulness on communication skills and creative characteristics. The study subjects were 249 children who attend kindergartens located in the Seoul and Gyeonggi-do area. A survey questionnaire was distributed to the children's mothers and teachers. The sample was analyzed using SPSS 21.0 and AMOS 21.0 program. The parameters were estimated by maximum likelihood method. The significance of indirect effect was tested by bootstrapping at .05 level. The results of this study were: (1) in both ages 4 and 5, playfulness had a direct and positive influence on communication skills, (2) in both ages, communication skills had a direct and positive effect on creative characteristics, and (3) the 5-year-old children's playfulness had a direct effect on creative characteristics, the 4-year-old children's playfulness did not exert direct influence onto creative characteristics. Communication skills 5-year-old children were seen to precipitate a partial mediation effect between playfulness and creative characteristics. At age 4, communication skills played a full mediation variable role between playfulness and creative characteristics. Discussions include suggestions to prosper creative characteristics through enhancing a child's playfulness and communication skills.