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Effects of γ-aminobutyric acid-enriched fermented sea tangle (Laminaria japonica) on brain derived neurotrophic factor-related muscle growth and lipolysis in middle aged women

  • Choi, Wook-chul;Reid, Storm N.S.;Ryu, Je-kwang;Kim, Yunsook;Jo, Young-Hong;Jeon, Byeong Hwan
    • ALGAE
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    • v.31 no.2
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    • pp.175-187
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    • 2016
  • This study evaluated the effects of γ-aminobutyric acid (GABA)-enriched fermented sea tangle (GFST), as a functional food, on brain derived neurotrophic factor (BDNF)-related muscle growth and lipolysis, in a sarcopenic obesity high-risk group. Twenty-one middle-aged women (53-63 y) participated in this randomized, double-blind, placebo controlled study. Participants ingested either 1,000 mg of GFST (n = 10) or a sucrose placebo (CON) (n = 11) everyday, for 8 weeks. Subjects were asked to abstain from any regular exercise. Fasting venous blood samples, body composition and muscular strength were measured before and after supplementation period. Collectively, we demonstrated that GFST significantly decreased total fat mass and triglyceride in body composition, as well as significantly increasing serum BDNF (p < 0.001), angiotensin converting enzyme (p < 0.001), human growth hormone and insulin-like growth factor-1 levels (p < 0.05 and p < 0.05, respectively) accompanied by increased total lean mass (p < 0.01). Furthermore, the reported improvements in total work, knee extension and flexion at 60° s−1 (p < 0.05), and peak torque normalized to body weight of knee flexion at 60° s−1 (p < 0.05), support an ergogenic effect of GABA associated with increased growth factor levels. The use of GFST, as a functional food ingredient, to elicit anti-obesity effects and stimulate the release of muscle-related growth factors with increasing serum BDNF levels may provide a protective intervention for age-related degeneration such as sarcopenic obesity.

Introduction to the Technology, Applications, Products, Markets, R&D, and Perspectives of Nanofoods in the Food Industry

  • Kim, Dong-Myong;Lee, Gee-Dong
    • Preventive Nutrition and Food Science
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    • v.11 no.4
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    • pp.348-357
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    • 2006
  • Nano is a unit that designates a billionth; accordingly nanotechnology could be described as the study and applications of the unique characteristics and phenomena of nanometer size materials. Applications of nanotechnology fall into two categories (one is top-down and the other is bottom-up). Currently, most products are the results of the top-down approach. Nanofoods have distinct functional characteristics stemming from the size, mass, chemical combinations, electrolytic features, magnetic properties of food sources at the nano level and which can be applied for safe absorption and delivery into the body. The greatest advantage of nanofood is that it permits the efficient use of small quantities of nutritional elements by increasing digestive absorption ability and by delivering natural elements without any change in their original characteristics. On the other hand, there are still unsolved problems, such as questions about safety and introduction of harmful material. The demand for new commercial food products is increasing, and commercial food producers are gradually combining nanotechnology and traditional food preparation methods. Nanofoods will improve our eating habits remarkably in the future. Tomorrow we will design nanofoods by shaping molecules and atoms. It will have a big impact on the food and food-processing industries. The future belongs to new products and new processes with the goals of customizing and personalizing consumer products. Nanotechnology is expected to be applied to not only foods themselves, but also to food packaging, production, safety, processing and storage. Also, it is believed that nanotechnology will be applied tracking finished products back to production facilities and even to specific processing equipment in those facilities. The aim of this study is the introduction of technology, applications, products, markets, R&D, and perspectives of nanofoods in the food industry.

Effect of Intake Flow Control Method on Part Load Performance in SI Engine(1) - Comparison of Throttling and Masking (스파크점화기관에서 흡기제어 방식이 부분부하 성능에 미치는 영향(1) - 스로틀링과 마스킹의 비교)

  • Kang, Min Gyun;Ohm, Inyong
    • Transactions of the Korean Society of Automotive Engineers
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    • v.22 no.2
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    • pp.156-165
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    • 2014
  • This paper is the first investigation on the effect of flow control methods on the part load performance in a spark ignition engine. For comparison of the methods, two control devices, port throttling and masking, were applied to a conventional engine without any design change of the intake port. Steady flow evaluation shows that steady flow rates per unit opening area and swirl ratio are very low compared with the port throttling and saturated from mid-stage valve lift, however, swirl increases slightly as the lift is higher in case of 1/4 masking control. In the part load performance, the effect of simple port throttling on lean misfire limit expansion is limited and insufficient; on the other hand a masking improves the limit considerably without any port modification for increasing swirl. Also the results show that the intake flow control improves the combustion with following two mechanisms: stratification induced by the combination of the flow pattern and the fuel injection timing attribute to ignition ability and the intensified flow ensure fast burn. In addition fuel consumption reduces under the flow controls and the reduction rate is different according to the operation conditions and control methods. At the Stoichiometric and/or low speed and low load the throttling method is more advantageous; however vice versa at lean and high load condition. Finally, the throttling is more efficient for HC reduction than masking, on the other side the NOx emissions increase under the masking and decrease under the port throttling compared with conventional port scheme.

Prevalence of Helminthic Infections among Inhabitants of Lao PDR

  • Eom, Keeseon S.;Yong, Tai-Soon;Sohn, Woon-Mok;Chai, Jong-Yil;Min, Duk-Young;Rim, Han-Jong;Jeon, Hyeong-Kyu;Banouvong, Virasack;Insisiengmay, Bounnaloth;Phommasack, Bounlay
    • Parasites, Hosts and Diseases
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    • v.52 no.1
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    • pp.51-56
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    • 2014
  • The prevalence of helminthic infections was surveyed on a total of 6,178 residents (males 2,549 and females 3,629) in 102 villages of 9 provinces in Lao PDR between 2007 and 2011 under the project of Korea-Laos Collaborative Project for Control of Foodborne Trematode Infections in Lao PDR. Fecal specimens were collected and examined by the Kato-Katz thick smear and Stoll's egg counting techniques. The overall liver/intestinal helminth egg positive rate was 71.9% with a single or mixed infections with Opisthorchis viverrini and minute intestinal flukes (Ov/MIF), Ascaris lumbricoides, hookworms, Trichuris trichiura, Trichostrongylus sp., echinostomes, Taenia spp., and others. Ov/MIF revealed the highest prevalence (55.6%) followed by hookworms (27.8%) and T. trichiura (6.5%). The endemic regions with the highest prevalence of Ov/MIF were Savannakhet, Khammouane, Vientiane (Nam Ngum), Champasak (Khong Island), and Saravane Province. High prevalences of A. lumbricoides (33.8%), hookworms (47.8%), and T. trichiura (32.6%) were observed in Phongsaly, Luang Prabang, and Vientiane (Nam Ngum) areas, respectively. The results of this study highlight helminth parasites of current public health significance in different areas of Lao PDR.

Effect of embryo and recipient condition on pregnancy rate following bovine embryo transfer (소 수정란이식(受精卵移植)에 있어서 수란우(受卵牛)와 수정란(受精卵)의 조건이 수태율(受胎率)에 미치는 영향)

  • Lee, Jung-ho;Park, Hang-kyun;Shin, Sang-tae
    • Korean Journal of Veterinary Research
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    • v.29 no.1
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    • pp.61-68
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    • 1989
  • This study was carried out to determine suitable selection factors for recipients and embryos which could improve pregnancy rates following bovine embryo transfer. The experiment included 52 surgical transfers from February, 1985 through June, 1986 performed on Kyungpook Breeding Center in southern Korea. The pregnancy rate was highest when recipients were in estrus within 6 hours before the donor to 12 hours after the donor (78.3% versus 50% for recipients in estrus earlier or later). Pregnancy rates were acceptable following culture under field conditions for up to 17 hours. More recipients over 15 months of age (76.1%) remained pregnant than those under 15 months (66.7%). Embryos transferred during the months from February to July resulted in higher pregnancy rates than those transferred during the remaining 6 months (77.3% versus 57.1%). Transferrable embryos were classified A (best) to C (worst); those graded A or B resulted in significantly higher pregnancy rates than those graded C (81.8% and 73.3% versus 25.0%, p<.05). Pregnancy rates among recipients of the Korean native breed tended to be higher than among Holstein recipients (100% versus 71.1%). Similarly, when the embryo was transferred to the right uterine horn, pregnancy rates tended to be higher than when it was transferred to the left (81.3% versus 65%). Pregnancy rates did not differ according to the stage of development of the embryo; they were for morulae, tight morulae, blastocysts, and advanced blastocysts, respectively: 75.0%, 66.7%, 75.0%, and 77.4%.

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Construction of EST Database for Comparative Gene Studies of Acanthamoeba

  • Moon, Eun-Kyung;Kim, Joung-Ok;Xuan, Ying-Hua;Yun, Young-Sun;Kang, Se-Won;Lee, Yong-Seok;Ahn, Tae-In;Hong, Yeon-Chul;Chung, Dong-Il;Kong, Hyun-Hee
    • Parasites, Hosts and Diseases
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    • v.47 no.2
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    • pp.103-107
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    • 2009
  • The genus Acanthamoeba can cause severe infections such as granulomatous amebic encephalitis and amebic keratitis in humans. However, little genomic information of Acanthamoeba has been reported. Here, we constructed Acanthamoeba expressed sequence tags (EST) database (Acanthamoeba EST DB) derived from our 4 kinds of Acanthamoeba cDNA library. The Acanthamoeba EST DB contains 3,897 EST generated from amebae under various conditions of long term in vitro culture, mouse brain passage, or encystation, and downloaded data of Acanthamoeba from National Center for Biotechnology Information (NCBI) and Taxonomically Broad EST Database (TBestDB). The almost reported eDNA/genomic sequences of Acanthamoeba provide stand alone BLAST system with nucleotide (BLAST NT) and amino acid (BLAST AA) sequence database. In BLAST results, each gene links for the significant information including sequence data, gene orthology annotations, relevant references, and a BlastX result. This is the first attempt for construction of Acanthamoeba database with genes expressed in diverse conditions. These data were integrated into a database (http://www. amoeba.or.kr).

Disaster Management and Disaster Medical Improvement in Underground Space (서울시 지하공간 재난관리 및 재난의료 개선방안)

  • Bae, Yoonshin;Park, Jihye
    • Journal of the Society of Disaster Information
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    • v.7 no.2
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    • pp.110-122
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    • 2011
  • In this study, the disaster management and disaster medical improvement was described in underground space(specifically underground shopping center) in case of fire disaster occurred. Firstly, statue and system was discussed concerning building law, safety, fire services, refuge. The underground in Seoul management is classified as to space and form and management agent is different according to the type form. Because the difficulty of emergency rescue arises due to individual management system unified system needs to be established and improvement of facility management agent is necessary. For the patient to be transfer on the ground, corporation between command head quarter and emergency rescue team are essential. And disaster information and emergency medical information are also need to be considered. Therefore, effective countermeasures for emergency saving is urgent considering distribution of medical institution and medical treatment.

Study on Sugar, Amino Acid, and Sensory Characteristics in Traditional Korean Gyupjang (Soy sauce) According to Different Methods (제조방법을 달리한 겹장의 당, 아미노산 분석 및 관능 특성에 관한 연구)

  • Kim, Kyungmin;Lee, Jiyoon;Chung, Rak Won
    • Journal of the Korean Society of Food Culture
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    • v.31 no.4
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    • pp.348-356
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    • 2016
  • The purpose of this study was to investigate the chemical contents (sugar, nitrogen, and amino acids) and sensory characteristics of traditional soy sauce according to three different methods. The samples were taken from four different periods (0, 20, 40, and 60 days after fermentation). Total sugar contents increased in all groups according to ripening period, and Gyupjang (G) showed the highest sugar content among the groups. Total nitrogen and amino acid contents of all groups increased after 60 days of ripening, and Gyupjang (G) and Gyupjang mixed with salt water (SG) had higher total nitrogen content compared to Chungjang (S) at the same period. The results from the sensory evaluation show that preferable sensory characteristics, such as color preferences, sweetness, umami taste, and overall preference, were significantly higher in Gyupjang (G) and Gyupjang mixed with salt water (SG) than in Chungjang (S). Preferable sensory characteristics had significantly high positive correlation with most amino acids, total nitrogen, and sugar contents, except for glutamine. Based on the significant difference in preferable sensory characteristics between Gyupjang mixed with salt water (SG) and Chungjang (S), Gyupjang mixed with salt water (SG) can be used to improve sensory characteristics. This research implies that adding salt water during the manufacturing Gyupjang process is advisable to yield high quality soy sauce.

Development of the Expert Education Program for the Management of Mental Health Prevention (정신건강예방관리 전문직 직무교육 프로그램 개발)

  • Park, Sung-Mi;Lee, Hyo-Young;Im, Hyuk;Chae, Eun-Hee;Kim, Hye-Sook
    • The Korean Journal of Health Service Management
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    • v.6 no.2
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    • pp.219-234
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    • 2012
  • Mental health service facilities implement an effort to meet the increased mental health demands. However, no specific 'mental health expert education program' have been offered yet. This study aimed to develop of the expert education programs which are general programs(GP), and specific programs(SP) for the management of mental health prevention in 3 kinds of facilities, psychosocial rehabilitation centers, homeless facilities, and domestic violence counselling facilities. Data were gathered from the service providers by structured questionnaire, and experts related with mental health by delphi study. We surveyed the management status and present expert programs. Consequently, domains of the education programs were extracted. As results, we identified the type of provider's job & demands for education. Thus, we gained the informations for developing the expert education programs in mental health facilities. GP were composed by 3 domains and 9 programs, and SP were composed by 3 programs each facilities. This study should be helpful in expanding the government educational operations related with mental health prevention areas. Eventually, community mental health will be promoted and socio-economic burdens by mental health problems will be lessened. In addition, it will be a basic evidence for developing specialized programs in a mental health prevention system foundation.

Effect of the family dentist system on oral health status of children and adolescents in Busan, Korea (치과주치의 사업이 아동·청소년의 구강건강에 미친 변화: 부산지역을 중심으로)

  • Kim, Min-Ji;Han, Dong-Hun;Kim, Jin-Bom
    • Journal of Korean society of Dental Hygiene
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    • v.13 no.3
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    • pp.501-507
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    • 2013
  • Objectives : The purpose of this study was to evaluate the effect of the family dentist system on oral health status of children and adolescents of Community Children's Centers in Busan, Korea. Methods : The subjects of this study were 81 children and adolescents, 6 to 14 years old, using Community Children's Centers. The oral health survey was conducted on the subjects from the starting stage of family dentist program in 2009 to the evaluation stage in 2010. Dental health status was examined by a trained dentist according to the guideline proposed by the World Health Organization. In addition, the information on the oral health knowledge, belief, and process of dental care were obtained using questionnaires. Data were analyzed using the paired samples t-test. Results : Percentages of subjects with fissure sealants on permanent teeth and filling rate among DMF teeth of 2010 year were higher than those of 2009 year (P<0.05). However, the rate of decayed teeth among DMF teeth of 2010 year was lower than those of 2009 year (p=0.049). Conclusions : These findings showed that the family dentist system brought a positive effect on caries prevention and proper dental care of children and adolescents of the Community Children's Centers.