• Journal of Ginseng Research
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• 제46권6호
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• pp.759-770
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• 2022

Background: Aerobic cellular respiration provides chemical energy, adenosine triphosphate (ATP), to maintain multiple cellular functions. Sirtuin 1 (SIRT1) can deacetylate peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1α) to promote mitochondrial biosynthesis. Targeting energy metabolism is a potential strategy for the prevention and treatment of various diseases, such as cardiac and neurological disorders. Ginsenosides, one of the major bioactive constituents of Panax ginseng, have been extensively used due to their diverse beneficial effects on healthy subjects and patients with different diseases. However, the underlying molecular mechanisms of total ginsenosides (GS) on energy metabolism remain unclear. Methods: In this study, oxygen consumption rate, ATP production, mitochondrial biosynthesis, glucose metabolism, and SIRT1-PGC-1α pathways in untreated and GS-treated different cells, fly, and mouse models were investigated. Results: GS pretreatment enhanced mitochondrial respiration capacity and ATP production in aerobic respiration-dominated cardiomyocytes and neurons, and promoted tricarboxylic acid metabolism in cardiomyocytes. Moreover, GS clearly enhanced NAD⁺-dependent SIRT1 activation to increase mitochondrial biosynthesis in cardiomyocytes and neurons, which was completely abrogated by nicotinamide. Importantly, ginsenoside monomers, such as Rg1, Re, Rf, Rb1, Rc, Rh1, Rb2, and Rb3, were found to activate SIRT1 and promote energy metabolism. Conclusion: This study may provide new insights into the extensive application of ginseng for cardiac and neurological protection in healthy subjects and patients.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제6권9호
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• pp.2098-2117
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• 2012

This paper jointly investigates the bandwidth allocation, transmission strategy and relay positions for two-way transmission aware cellular networks with network coding (NC). Our goal is to minimize the transmission power of mobile terminals (MTs). Consider a cellular system, where multiple MTs exchange information with their common base station, firstly, we propose an efficient bandwidth allocation method and then give a transmission strategy for each MT to determine whether to use relay stations (RSs) for its two-way transmission with the BS or not. To further improve the system performance, the optimal positions of RSs are also jointly discussed. A GA-based algorithm is presented to obtain the optimum positions for RSs. Besides, the impacts of frequency reuse on MT's transmission power and system spectral efficiency (SE) under different number of relays are also discussed in our work. Numerical results show that the proposed NC aware scheme can extend MTs' battery life at least 6% more than traditional method.

• 전기화학회지
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• 제10권1호
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• pp.31-35
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• 2007

이 리뷰를 통하여, 휴대폰용 리튬이차전지의 최근 기술동향을 설명하였다. 휴대폰용 이차전지로는 니카드, 니켈-금속수소, 리튬이온 혹은 리튬이온폴리머의 세 가지 형태의 전지가 있으며, 리튬 이차전지가 에너지밀도 측면에서 가장 성능이 우수하다. 즉, 동일한 용량을 갖는 이차전지 가운데 가장 작고 가벼운 것은 리튬이차전지이다. 이러한 리튬이차전지의 시장은 매년 약 15%의 높은 성장을 기록하고 있다. 연구개발은 $LiFePO_4$를 포함하는 새로운 양극, $Li_4Ti_5O_{10}$, Si, 주석 등의 새로운 음극소재, 새로운 전해질과 안정성 확보에 관한 것을 중심으로 진행되고 있다.

• 대한기계학회논문집A
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• 제31권6호
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• pp.694-700
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• 2007

Recently, a new cellular metal, WBK(Wire woven Bulk Kagome) has been introduced. WBK is fabricated by assembling metal wires in six directions into a Kagome-like truss structure and by brazing it at all the crossings. Wires as the raw material are easy to handle and to attain high strength with minimum defect. And the strength and energy absorption are superior to previous cellular metals. Therefore, WBK seems to be promising once the fabrication process for mass production is developed. In this paper, an upper bound solution for the mechanical properties of the bulk WBK under compression is presented. In order to simulate uniform behavior of WBK consisted of perfectly uniform cells, a unit cell of WBK with periodic boundary conditions is analyzed by the finite element method. In comparison with experimental test results, it is found that the solution provides a good approximation of the mechanical properties of bulk WBK cellular metals except for Young's modulus. And also, the brazing joint size does not have any significant effect on the properties with an exception of an idealized thin joint.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제12권12호
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• pp.5701-5722
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• 2018

The continuous increase in the cost of energy production and concerns for environmental sustainability are leading research communities, governments and industries to amass efforts to reduce energy consumption and global $CO_2$ footprint. Players in the information and communication industry are keen on reducing the operational expenditures (OpEx) and maintaining the profitability of cellular networks. Meanwhile, network virtualization has been proposed in this regard as the main enabler for 5G mobile cellular networks. In this paper, we propose a generic framework of slice resource provisioning and customized physical resource allocation for energy-efficiency and quality of service optimization. In resource slicing, we consider user demand and population resources provisioning scheme aiming to satisfy quality of service (QoS). In customized physical resource allocation, we formulate this problem with an integer non-linear programming model, which is solved by a heuristic algorithm based on minimum vertex coverage. The proposed algorithm is compared with the existing approaches, without consideration of slice resource constraints via system-level simulations. From the perspective of infrastructure providers, traffic is scheduled over a limited number of active small-cell base stations (sc-BSs) that significantly reduce the system energy consumption and improve the system's spectral efficiency. From the perspective of virtual network operators and mobile users, the proposed approach can guarantee QoS for mobile users and improve user satisfaction.

• 한국패류학회지
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• 제32권1호
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• pp.45-54
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• 2016

환경오염 평가를 위한 생물지표로 세포내 에너지할당(CEA) 의 적용성을 검토하기 위해 바지락 (Ruditapes philippinarum) 조직을 대상으로 에너지 함량과 에너지 소비율을 분석하였다. 원유를 인위적으로 오염시킨 퇴적물에 바지락을 1, 2, 4, 7, 10 일간 노출 후 일부 조직 (발, 입출수공, 아가미 그리고 몸통) 내 지질, 글루코오스, 단백질 함량, 그리고 전자전달계 (electron transport system, ETS) 활성을 측정하였다. 바지락의 체내 지질, 글루코오스, 단백질 에너지 함량(energy available, EA)은 오염의 수준과 노출시간이 증가함에 따라 감소하였으나, 이와 대조적으로 ETS 활성은 그 반대의 경향을 보였다. 바지락의 조직별 EA는 발 > 입출수공 > 아가미 > 몸통 순이었다. EA와 EC의 분석에서 통계적으로 유의한 차이는 노출 최고 농도 (58.3 mg TPAHs/kg DW) 에서만 발견되었다. 노출 1 일째 발과 아가미에서, 노출 2, 7 일째 몸통에서 EA가 감소하였고, 노출 4 일째 몸통에서 EC가 증가하였다. CEA는 EA 또는 EC 보다 오염에 더 민감하게 반응하였다. 특히, 노출 1-7 일 기간 동안 몸통에서 CEA는 오염 수준이 낮은 (6.5 mg TPAHs/kg DW) 범위에서도 크게 감소하였다. CEA는 급성독성이 나타나지 않는 낮은 수준의 퇴적물오염 평가에서 EA 또는 EC보다 더 민감하였다. 바지락을 이용한 오염 퇴적물 평가시 노출은 4 일간, 그리고 몸통부위에서 CEA를 측정하는 것이 가장 민감하고 신뢰할 수 있을 것으로 여겨진다.

• 한국통신학회논문지
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• 제39B권2호
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• pp.53-60
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• 2014

최근 전력난으로 인해 각 분야에서 에너지 절감을 위한 기술에 대한 연구가 활발하게 진행됨에 따라 네트워크분야에서도 에너지 절감을 위한 연구가 활발히 진행되고 있다. 본 논문에서는 변화하는 트래픽 밀도에 따라 기지국의 전송파워를 조절하여 트래픽이 없거나 적은 경우 발생하는 불필요한 기지국의 에너지 소모를 줄임으로서 기지국의 소모 에너지를 절감하는 셀 주밍 기법을 제안하고, 트래픽의 변화에 따른 기지국의 서비스 시나리오를 비교하여 에너지 절감을 확인하였다.

• Clinical and Experimental Pediatrics
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• 제48권2호
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• pp.126-137
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• 2005

New insights in the complex metabolic pathways and its control mechanism for energy homeostasis have refined our understanding of the pathophysiology of obesity. It is now recognized that there are several additional regulatory mechanism such as peripheral signals including leptin, ghrelin, GLP-1 and PYY and cellular signals including uncoupling proteins and ${\beta}$ Adrenergic receptors, which contribute to the regulation of food intake and energy expenditure, respectively. In addition, the function of adipocyte as an endocrine organ in energy homeostasis has been recently emphasized. Recent findings suggest that elevated levels of adipokines, such as leptin, adiponectin, resistin and TNF-${\alpha}$, in addition to increased free fatty acid level could be related to the pathophysiology of insulin resistance in obesity. For effective treatments and prevention of obesity, further studies on the circuits of neural and endocrine interactions in the regulation of energy homeostasis are needed.

• Journal of Communications and Networks
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• 제6권4호
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• pp.397-402
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• 2004

Location management is difficult in ad hoc networks due to many features such as the lack of a wired infrastructure, the scarce energy, memory and processing capabilities of nodes, and nodes’ movement which leads to a dynamic topology. These characteristics make the location management schemes designed for mobile cellular networks inefficient for ad hoc networks. New solutions for location management have therefore been proposed in the literature in the recent past. In this paper, a taxonomy of location management strategies is presented; some of the more interesting approaches proposed in the literature are critically discussed, highlighting their advantages and disadvantages.

• 대한화장품학회지
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• 제39권1호
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• pp.1-8
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• 2013

본 연구에서는 한국과 중국 감초(Glycyrrhiza uralensis) 및 우즈베키스탄 감초(Glycyrrhiza glabra)를 이용하여 원산지별 감초 추출물의 항산화 활성에 관한 비교 연구를 수행하였다. 감초 추출물의 자유 라디칼(1, 1-phenyl-2-picrylhydrazyl, DPPH) 소거활성($FSC_{50}$)은 각 3가지 원산지 중 한국 감초가 50% 에탄올 추출물(21.15 ${\mu}g/mL$), 에틸아세테이트 분획(29.15 ${\mu}g/mL$), 아글리콘 분획(3.26 ${\mu}g/mL$)에서 모두 가장 우수한 활성을 나타내었다. 루미놀-의존성 화학발광법을 이용한 $Fe^{3+}-EDTA/H_2O_2$ 계에서 생성된 활성산소종(reactive oxygen species, ROS)에 대한 감초 추출물의 총 항산화능($OSC_{50}$)은 중국 감초의 50% 에탄올 추출물(1.00 ${\mu}g/mL$)과 에틸아세테이트 분획(0.34 ${\mu}g/mL$)이 가장 높은 활성을 나타내었다. Rose-bengal로 증감된 사람 적혈구의 광용혈에 대한 억제 효과를 측정하였을 때 원산지별 감초의 50% 에탄올 추출물과 아글리콘 분획 모두 농도범위(5 ~ 50 ${\mu}g/mL$)에서 농도의존적으로 세포 보호 효과를 나타내었으며, 특히 아글리콘 분획(10 ${\mu}g/mL$)의 경우 한국 감초(${\tau}_{50}$ = 847.4 min)가 동일한 종인 중국 감초(${\tau}_{50}$ = 194.3 min)보다 약 4배 더 우수한 활성을 나타내었다. 이상의 결과를 통해 미백 소재로만 주로 사용되어오던 감초 추출물이 천연 항산화제로서 화장품 분야에 응용될 수 있을 것으로 예상된다. 특히 세포보호 효과가 우수한 것으로 보아 감초 추출물이 자외선으로 유도된 $^1O_2$와 외 ROS로부터 피부를 효과적으로 보호할 수 있을 것으로 예상된다.