• Title/Summary/Keyword: cell width

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Red Cell Distribution Width as a Predictor of Prostate Cancer Progression

  • Albayrak, Sebahattin;Zengin, Kursad;Tanik, Serhat;Bakirtas, Hasan;Imamoglu, Abdurrahim;Gurdal, Mesut
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.18
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    • pp.7781-7784
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    • 2014
  • Background: The aims of this study were to investigate the utility of red blood cell distribution width (RDW) as a simple and readily available marker in prostate cancer, as well as to evaluate RDW as a predictor of progression in prostate cancer patients. Materials and Methods: We evaluated 62 newly diagnosed prostate cancer patients who underwent transrectal ultrasound (TRUS)-guided biopsy and 62 healthy controls of mean age 64 (range, 45-75) years at the Urology Clinic of Bozok University Hospital. Data collection was performed using our laboratory information system database to retrieve findings regarding RDW, hemoglobin, prostatespecific antigen (PSA), and age. The RDW values were compared between the healthy control group and prostate cancer patients. A high risk of progression as defined as a Gleason score (GS) >6, total number of cores positive for cancer >33%, each core containing >50% cancer cells, and a prostate-specific antigen (PSA) level >10 ng/mL. Patients were classified according to risk of progression, as well as divided into subgroups according to the RDW quartile. Results: The mean RDW value of prostate cancer patients was 14.6, compared with 13.7 in the healthy control group (p=0.001). A higher RDW was associated with an increased risk of progression, whereas a lower RDW value was correlated with a low risk of progression. Conclusions: RDW is an easily derived measure that might, in combination with other markers, help predict prostate cancer risk and progression. We suggest that RDW may be used in combination with other parameters in the assessment of prostate cancer.

Numerical Investigation on Initiation Process of Spherical Detonation by Direct Initiation with Various Ignition Energy

  • Nirasawa, Takayuki;Matsuo, Akiko
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2008.03a
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    • pp.45-52
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    • 2008
  • In order to investigate the initiation and propagation processes of a spherical detonation wave induced by direct initiation, numerical simulations were carried out using two-dimensional compressible Euler equations with an axisymmetric assumption and a one-step reaction model based on Arrhenius kinetics with various levels of ignition energy. By varying the amount of ignition energy, three typical initiation behaviors, which were subcritical, supercritical and critical regimes, were observed. Then, the ignition energy of more than $137.5{\times}10^6$ in non-dimensional value was required for initiating a spherical detonation wave, and the minimum ignition energy(i.e., critical energy) was less than that of the one-dimensional simulation reported by a previous numerical work. When the ignition energy was less than the critical energy, the blast wave generated from an ignition source continued to attenuate due to the separation of the blast wave and a reaction front. Therefore, detonation was not initiated in the subcrtical regime. When the ignition energy was more than the minimum initiation energy, the blast wave developed into a multiheaded detonation wave propagating spherically at CJ velocity, and then a cellular pattern radiated regularly out from the ignition center in the supercritical regime. The influence on ignition energy was observed in the cell width near the ignition center, but the cell width on the fully developed detonation remained constant during the expanding of detonation wave due to the consecutive formation of new triple points, regardless of ignition energy. When the ignition energy was equal to the critical energy, the decoupling of the blast wave and a reaction front appeared, as occurred in the subcrtical regime. After that, the detonation bubble induced by the local explosion behind the blast wave expanded and developed into the multiheaded detonation wave in the critical regime. Although few triple points were observed in the vicinity of the ignition core, the regularly located cellular pattern was generated after the onset of the multiheaded detonation. Then, the average cell width on the fully developed detonation was almost to that in the supercritical regime. These numerical results qualitatively agreed with previous experimental works regarding the initiation and propagation processes.

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Design and Growth of InAs Multi-Quantum Dots and InGaAs Multi-Quantum Wells for Tandem Solar Cell (텐덤형 태양전지를 위한 InAs 다중 양자점과 InGaAs 다중 양자우물에 관한 연구)

  • Cho, Joong-Seok;Kim, Sang-Hyo;HwangBoe, Sue-Jeong;Janng, Jae-Ho;Choi, Hyon-Kwang;Jeon, Min-Hyon
    • Journal of the Korean Vacuum Society
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    • v.18 no.5
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    • pp.352-357
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    • 2009
  • The InAs multi-quantum dots (MQDs) solar cell and InGaAs multi-quantum wells (MQWs) solar cell to cover 1.1 eV and 1.3 eV were designed by 1D poisson, respectively. The MQDs and MQWs of 5, 10, 15 layers were grown by molecular beam epitaxy. The photo luminescence results showed that the 5 period stacked MQDs have the highest intensity at around 1.1 eV with 57.6 meV full width at half maximum (FWHM). Also we can observe 10 period stacked MQWs peak position which has highest intensity at 1.31 eV with 12.37 meV FWHM. The density and size of QDs were observed by reflection high energy electron diffraction pattern and atomic force microscope. Futhermore, AlGaAs/GaAs sandwiched tunnel junctions were modified according to the width of GaAs layer on p-type GaAs substrates. The structures with GaAs width of 30 nm and 50 nm have backward diode characteristics. In contrast, tunnel diode characteristics were observed in the 20 nm of that of sample.

A One-Pass Standard Cell Placement Algorithm Using Multi-Stage Graph Model (다단 그래프 모델을 이용한 빠른 표준셀 배치 알고리즘)

  • 조환규;경종민
    • Journal of the Korean Institute of Telematics and Electronics
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    • v.24 no.6
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    • pp.1074-1079
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    • 1987
  • We present a fast, constructive algorithm for the automatic placement of standard cells, which consists of two steps. The first step is responsible for cell-row assignment of each cell, and converts the circuit connectivity into a multi-stage graph under to constraint that sum of the cell-widths in each stage of the multi-state graph does not exceed maximum cell-row width. Generatin of feed-through cells in the final layout was shown to be drastically reduced by this step. In the second step, the position of each cell within the row is determined one by one from left to right so that the cost function such as the local channel density is minimized. Our experimental result shows that this algorithm yields near optimal results in terms of the number of feed-through cells and the horizontal tracks, while running about 100 times faster than other iterative procedures such as pairwise interchange and generalized force directed relaxation method.

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A Study on Uniformity of Current Distribution in Hull Cell (Hull Cell에서 전류분포의 균일화에 관한 연구)

  • 여운관
    • Journal of the Korean institute of surface engineering
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    • v.27 no.6
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    • pp.340-346
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    • 1994
  • The method of uniforming current distribution in Hull cell are studied by using auxiliary anode, current shield bipolar electrode, and combinings bipolar electrode with current shield in order to find a way of uni-form deposition. The current density distributions are measured by each ammeter of the same inner resistance connected to divided cathode pannel respectively. The current density distributions of cathode electrode divided into five sections with 5mm width have a tendency of linear inclination, and that of twenty sections have a tendency of smoother curve than the curve of original Hull cell pannel. Their results showed lower value on the high current density portion and higher value on the low portion than that original Hull cell pannel. The current distribution in Hull cell is able to unify by using auxiliary anode, or combining bipo-lar electrode with current shield, but not efficient in using one of both individually.

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Design analysis of high efficiency crystalline silicon solar cell using the selective emitter (선택적 에미터를 적용한 고효율 결정질 실리콘 태양전지 구조 설계)

  • Lim, Jong-Keun;Lee, Won-Jae;Moon, In-Sik;Oh, Hoon;Cho, Eun-Chel
    • 한국신재생에너지학회:학술대회논문집
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    • 2009.11a
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    • pp.355-358
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    • 2009
  • This paper presents the technology of selective emitter for high efficiency crystalline silicon solar cell. The effect of selective emitter is analyzed by using the simulation program for solar cell, PC1D. The selective emitter shows better spectral response in short wavelength regions compared to homogeneous emitter. Therefore, the efficiency of solar cell with selective emitter can be improved by changing the sheet resistance from 60 $\Omega/\square$ to 120 $\Omega/\square$. In addition, the power loss of solar cell can be minimized by optimizing width and gap of the finger electrodes on the selective emitter.

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Electron Microscopic Visualization of Bacillus thuringiensis (Bacillus thuringiensis의 전자현미경적(電子顯微鏡的) 연구(硏究))

  • Choi, Y.H.;Kim, K.S.;Lee, H.H.
    • Applied Microscopy
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    • v.13 no.1
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    • pp.63-70
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    • 1983
  • The cell division of Bacillus thuringiensis are studed by a electron microscope. It was observed that when the cell division was occurred, the bacterial transverse septeum was centripetally formed, and the bacterial spore was divided into two daughter cells. The fore spore septum was initiated by invagination from either sides of the cell membranes, and was easily distinguished it from the transverse septum of the vegetative cell division. The large vesicular mesosome was. observed at one end of the cell membrane. The nucleoids were of variously irregular shapes and had no a nuclear membrane. The morphology of the bacteria was visualizd by a scanning electron microscope. The surface of the cell was generally rough and had a single polar flagellum, which was appeared to be $0.2{\mu}$ in width and $13{\mu}$ in length.

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Effects of TESTIN Gene Expression on Proliferation and Migration of the 5-8F Nasopharyngeal Carcinoma Cell Line

  • Zhong, Zhun;Zhang, Fei;Yin, Shu-Cheng
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.6
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    • pp.2555-2559
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    • 2015
  • Purpose: To investigate effects of the TESTIN (TES) gene on proliferation and migration of highly metastatic nasopharyngeal carcinoma cell line 5-8F and the related mechanisms. Materials and Methods: The target gene of human nasopharyngeal carcinoma cell line 5-8F was amplified by PCR and cloned into the empty plasmid pEGFP-N1 to construct a eukaryotic expression vector pEGFP-N1-TES. This was then transfected into 5-8F cells. MTT assays, flow cytometry and scratch wound tests were used to detect the proliferation and migration of transfected 5-8F cells. Results: A cell model with stable and high expression of TES gene was successfully established. MTT assays showed that the OD value of 5-8F/TES cells was markedly lower than that of 5-8F/GFP cells and 5-8F cells (p<0.05). Flow cytometry showed that the apoptosis rate of 5-8F/TES cells was prominently increased compared with 5-8F/GFP cells and 5-8F cells (p<0.05). In vitro scratch wound assays showed that, the width of the wound area of 5-8F/TES cells narrowed slightly, while the width of the wound area of 5-8F/ GFP cells and 5-8F cells narrowed sharply, suggesting that the TES overexpression could inhibit the migration ability. Conclusions: TES gene expression remarkably inhibits the proliferation of human nasopharyngeal carcinoma cell line 5-8F and reduces its migration in vitro. Thus, it may be a potential tumor suppressor gene for nasopharyngeal carcinoma.

Design of the Wideband Microwave Absorber for X-band Applications (X-대역 응용을 위한 광대역 전파 흡수체 설계)

  • Hong, Young-Taek;Jeoung, Gu-Ho;Choi, Jaehoon
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.28 no.9
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    • pp.749-755
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    • 2017
  • In this paper, a wideband microwave absorber for X-band(8~12 GHz) applications is proposed. The structure of the proposed absorber unit cell consists of a resonator with a slot and slit, a backing ground plate, and a Taconic RF-30(${\varepsilon}_r=3$, $tan{\delta}=0.0014$) substrate with a dimension of $8.5{\times}8.5{\times}0.5mm^3$. The proposed absorber has a dual resonance at 9.83 and 10.37 GHz. To demonstrate the operating principle of the proposed absorber structure at each resonance frequency, the simulated current distributions on the unit cell are analyzed. To verify the performance of the proposed absorber, a prototype absorber was fabricated with a planar array of $20{\times}20$ unit cells. The measured results exhibit two absorptivity peaks stronger than 99 % and full-width at half-maximum(FWHM) bandwidth of 1.1 GHz(9.51~10.61 GHz).

Study on optimum structure of free-breathing Polymer Electrolyte Membrane Fuel Cell (PEMFC) for robotic application (로봇용 자연급기형 연료전지의 최적구조에 관한 연구)

  • Choi, Jae-Hyuk;Park, Sang-Kyun
    • Journal of Advanced Marine Engineering and Technology
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    • v.30 no.2
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    • pp.231-238
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    • 2006
  • The performance of free-breathing polymer electrolyte membrane fuel cell (PEMFC) was studied experimentally and the effect of cathode separator structure on the cell performance was investigated. Cathode separators were used for the cell with $18cm^2$ active area. In channel type, the contact resistance is low, and the nature convection. which is strongly affected by the cross-sectional shape of cathode separator channel, is dominant in a cell performance. The maximum power density with $18cm^2$ active area is $105mW/cm^2$ using the 10mm depth and 2mm width channel. A computational analysis was optimum structure of free-breathing channel type PEMFC for robotic application.