• 제목/요약/키워드: cell infection

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Identification of a Prophage-encoded Abortive Infection System in Levilactobacillus brevis

  • Feyereisen, Marine;Mahony, Jennifer;O'Sullivan, Tadhg;Boer, Viktor;van Sinderen, Douwe
    • 한국미생물·생명공학회지
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    • 제48권3호
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    • pp.322-327
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    • 2020
  • Abortive infection systems (Abi) are phage resistance systems that can be prophage-encoded. Here, two genes encoding an Abi system were identified on a prophage sequence contained by the chromosome of the Levilactobacillus brevis strain UCCLBBS124. This Abi system is similar to the two-component AbiL system encoded by Lactococcus lactis biovar. diacetylactis LD10-1. The UCCLBBS124 prophage-derived Abi system (designated here as AbiL124) was shown to exhibit specific activity against phages infecting L. brevis and L. lactis strains. Expression of the AbiL124 system was shown to cause reduction in the efficiency of plaquing and cell lysis delay for phages of both species.

침윤성 Streptococcus pneumoniae 감염에 의한 비전형적 용혈성 요독 증후군 1 례 (A Case of Atypical Hemolytic Uremic Syndrome Associated with Invasive Streptococcus pneumoniae Infection)

  • 황수자;유은선;이승주
    • Childhood Kidney Diseases
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    • 제3권1호
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    • pp.104-108
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    • 1999
  • Atypical hemolytic uremic syndrome associated with neuraminidase-producing Streptococcus pneumoniae usually associated with invasive infection such as fulminant pneumonia, sepsis, and meningitis and may occur earlier in lift and has a higher mortality rate than typical hemolytic uremic syndrome. We have experienced a 22-month-old female patient with hemolytic uremic syndrome associated with S. pneumoniae pneumonia and empyema. The patient was treated with ceftriaxone and washed red blood cell transfusion. As the disese course could be aggravated by the use of blood products containing anti-Tomsen-Friedenreich antigen, early recognition and sensible use of blood products such as washed RBC might lead to the improved outcome.

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경남 북부지역에서 도축된 한우의 간질 감염율과 혈액성장의 변화에 관한 연구 (Prevalence of Fascioliasis and changes in blood components in slaughtered Korean native cattle of North Kyeongnam area)

  • 서득록;이국천;이순선;김종수;김충희
    • 한국동물위생학회지
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    • 제18권2호
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    • pp.158-162
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    • 1995
  • An abattoir survey was carried out on 300 Korean native cattles reared and slaughtered in North Kyeongnam area to determine the prevalence of Fasciola hepatica infections. The average prevalence of fascioliasis was 46.4% ; the infection rate had a tendency to increase with age. Some hematological and biochemical indices were assayed in Korean native cattle naturally harbouring Fasciola hepatica infection and compared with uninfection control. Affected animal revealed reduction total erythrocyte count and hemoglobin, which was consistent in total leucocyte count and packed cell volume. Infected cattle had lower level of serum total protein and albumin, was consistent serum calcium and glucose indices, had higher levels of SGOT, SGPT and cholesterol indices.

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양 폐충 감염증에 의한 전신 호산구 침윤증 (Systemic Eosinophil Infiltration by Ovine Lungworm Infection)

  • 김옥진
    • 한국수의병리학회지
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    • 제6권1호
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    • pp.7-9
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    • 2002
  • Case 1 was showed severe caughing and nasal discharge, who was one of 5-month-old 18 male sheep taking inspection for MCF experiment. Pathological examination of case 1 was conducted. Macroscopic observations were the foamy sticky fluids in nasal and tracheal cavity, the grey spots with 2-4 mm diameter on the surface of lung. Histopathological observations were severe eosinophil and other round cell infiltration in general organs including lung, trachea, small intestine, large intestine, liver. Also, in the lung, there were parasite-cutting lesions in some alveolar spaces and bronchioles. Following these observations, case 1 was diagnosed as ovine lungworm infection.

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광주지역에서 발생한 토끼 Eimeria stiedae 감염증 (Outbreak of Eimeria stiedae infection in a rabbit farm in Kwangju)

  • 배성열;김철희;고바라다;박성도;나호명;김용환;오대영
    • 한국동물위생학회지
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    • 제21권4호
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    • pp.385-390
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    • 1998
  • A rabbit farm reared about 500 New Zealand White in Kwangju city was occurred Eimeria stiedae infection. Morbidity and cumulative mortality were more than 39% and 14%, respectively, from May, 1997 to March, 1998. Most of cases with severe diarrhea were belong to younger than 2-month old. In necrospy, there were multifocally white nodules with about 1-5mm in diameter on the liver surface and dark greenish mucous exudate in intestinal lumen. Main microscopic lesions included marked hyperplasia of the bile duct epitheilia containing different developmental stages of Eimeria stiedae and inflammatory cell infiltration, and the degeneration of small intestinal epithelia. Many oocysts of Eimeria stiedae were detected in the intestinal contents and epithelia, the feces, the bile juice, the bile duct and the liver.

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Interleukin-32 in Inflammatory Autoimmune Diseases

  • Kim, Soohyun
    • IMMUNE NETWORK
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    • 제14권3호
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    • pp.123-127
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    • 2014
  • Interleukin-32 (IL-32) is a cytokine inducing crucial inflammatory cytokines such as tumor necrosis factor-${\alpha}(TNF{\alpha})$ and IL-6 and its expression is elevated in various inflammatory autoimmune diseases, certain cancers, as well as viral infections. IL-32 gene was first cloned from activated T cells, however IL-32 expression was also found in other immune cells and non-immune cells. IL-32 gene was identified in most mammals except rodents. It is transcribed as multiple-spliced variants in the absence of a specific activity of each isoform. IL-32 has been studied mostly in clinical fields such as infection, autoimmune, cancer, vascular disease, and pulmonary diseases. It is difficult to investigate the precise role of IL-32 in vivo due to the absence of IL-32 gene in mouse. The lack of mouse IL-32 gene restricts in vivo studies and restrains further development of IL-32 research in clinical applications although IL-32 new cytokine getting a spotlight as an immune regulatory molecule processing important roles in autoimmune, infection, and cancer. In this review, we discuss the regulation and function of IL-32 in inflammatory bowel diseases and rheumatoid arthritis.

Disseminated Herpes Zoster in an Immunocompetent Elderly Patient

  • Yoon, Keon Jung;Kim, Su Hwa;Lee, Eun Ha;Choi, Ji Hye
    • The Korean Journal of Pain
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    • 제26권2호
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    • pp.195-198
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    • 2013
  • Herpes zoster is a cutaneous infection that is characterized by an acute vesicobullous rash with ipsilateral one or two dermatomal distribution and painful allodynia, while predominantly being found in the elderly. Extensive cutaneous dissemination has been reported in immune-compromised patients, such as those who suffer from HIV infections, cancer, chemotherapy, and corticosteroid therapy patients. However, we report a case of disseminated herpes zoster infection in an immuno-competent elderly individual.

Ultrastructure of Compatible and Incompatible Interactions of Pumpkin Stems Infected with Phytophthora capsici

  • Lee, Byung-Kook;Hong, Jeum-Kyu;Hwang, Byung-Kook
    • The Plant Pathology Journal
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    • 제17권1호
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    • pp.29-35
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    • 2001
  • Early infection process of Phytophthora capsici in pumpkin stems was similar in the compatible and incompatible interactions 24 h after inoculation. Intercellularly growing hyphae penetrated host parenchyma cells by growing hyphae penetrated host parenchyma cells by forming haustoria. An extrahaustorial matrix was found around the haustoria in both compatible and incompatible interactions. No wall appositions were observed at the infection sites in the parenchyma cells. In the compatible interaction, infecting hyphae grew well in the intercellular spaces between xylem vessels in stem tissues. Degraded host cell wall, plasmolysis of plasma membrane, and degenerated chloroplasts were pathological features of pumpkin stem tissues in both compatible and incompatible interactions. A characteristic host response in the resistant pumkin cultivar Danmatmaetdol was rapid cytoplasmic movement of host cells toward the oomycete haustoria.

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재래산양의 Anaplasma spp 감염에 대한 혈액학적 및 혈청학적 조사 (Hematological and Serological Survey to Anaplasma spp in Goat)

  • 박경옥;이정아;오강희;박영구
    • 한국동물위생학회지
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    • 제20권2호
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    • pp.217-223
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    • 1997
  • To investigate infection rates of Anaplasma spp in Red Blood Cell(RBC) of 209 goats and to detect the Anaplasma antibody in sera of 242 goats by Complement Fixation test (CF test), the present study was practiced. The obtained results were as follows : 1. Infection rates of Anaplasma spp in RBC of blood smears, stained by the Giemsa method, were seasonally 15.3% in spring, 20.0% in summer, 39.3% In fall, 16.9% in winter, respectively. 2. The positive rates of the Anaplasma antibody in sera of goats tested by CF test were seasonally 80.2% In spring, 79.0% in summer, 85.7% in fall, 62.0% In winter, respectively.

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자카스펭귄에서 발생한 Aspergillus fumigatus 감염증 (Aspergillus fumigatus infection in Jackass penguin)

  • 김규태;조성환;손화영;류시윤
    • 대한수의학회지
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    • 제44권4호
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    • pp.615-619
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    • 2004
  • A three years old male Jackass penguin(Spheniscus demersus) showed anorexia, depression, respiratory problem for a few days, followed by clinical treatment for 20 days resulted in death. Grossly, multiple white nodules measuring 2~3 mm in diameter were observed in the surface of and inside lung, liver, kidney, thoracic wall. Microscopically, granuloma formations were observed in the lung and liver. The margin of granuloma surrounded by connective tissue barrier and infiltrated lymphocytes, and also observed giant cell near the granuloma. By Periodic acid Schiff reaction, hyphae were detected in granuloma of lung and liver. This case was a chronic and systemic aspergillosis caused by Aspergillus fumigatus infection in a Jackass penguin at a zoo.