• Title/Summary/Keyword: cell coordination

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A novel cis/trans-diaminocyclohexane platinum coordination complexes possessing in vitro and in vivo antitumor activity

  • Jung, Jee-Chang;Chang, Sung-Goo;Lee, Kyung-Tae;Park, Young-Soo;Lee, Joo-Han;Lee, Kyou-Heung;Kim, Sang-Lin
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1997.04a
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    • pp.111-111
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    • 1997
  • As part of a drug discovery program to develope more effective platinum-based anticancer drugs, a series of platinum complexes trans-diaminocyclohexane platinum bi sdiphenylphosphino - ethane ( KHPC- 002) cis-diaminocyclohexane platinum bi sdiphenylphosphino - ethane ( KHPC- 006) has been evaluated in vitro against 4 human carcinoma cell lines with those of cisplatin using a tetrazolium-based colorimetric assay (MTT assay). The cell lines were two human bladder carcinoma cell lines, HT-1197 and HT-1376, human colon carcinoma cell line, HCT-116, and prostate cancer cell line DU-145. in vitro cytotoxic potential of each platinum complex was expressed as the cytotoxicity index (Cl, %).

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The Role of Cytoskeletal Elements in Shaping Bacterial Cells

  • Cho, Hongbaek
    • Journal of Microbiology and Biotechnology
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    • v.25 no.3
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    • pp.307-316
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    • 2015
  • Beginning from the recognition of FtsZ as a bacterial tubulin homolog in the early 1990s, many bacterial cytoskeletal elements have been identified, including homologs to the major eukaryotic cytoskeletal elements (tubulin, actin, and intermediate filament) and the elements unique in prokaryotes (ParA/MinD family and bactofilins). The discovery and functional characterization of the bacterial cytoskeleton have revolutionized our understanding of bacterial cells, revealing their elaborate and dynamic subcellular organization. As in eukaryotic systems, the bacterial cytoskeleton participates in cell division, cell morphogenesis, DNA segregation, and other important cellular processes. However, in accordance with the vast difference between bacterial and eukaryotic cells, many bacterial cytoskeletal proteins play distinct roles from their eukaryotic counterparts; for example, control of cell wall synthesis for cell division and morphogenesis. This review is aimed at providing an overview of the bacterial cytoskeleton, and discussing the roles and assembly dynamics of bacterial cytoskeletal proteins in more detail in relation to their most widely conserved functions, DNA segregation and coordination of cell wall synthesis.

Analysis on Interference Control in Heterogeneous Networks (이기종 네트워크에서의 간섭 제어 분석)

  • Kim, Seong-Eui;Kim, Ki-Su;Hong, Een-Kee
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.38A no.3
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    • pp.268-276
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    • 2013
  • In this paper, we introduce the technologies to handle the interference in the heterogeneous network and evaluate the performance of enhanced Inter-Cell Interference Coordination (enhanced ICIC, eICIC) techniques that are being introduced in 3GPP Release 10. In the time-domain eICIC scheme, time-domain resources are scheduled to avoid the interference by using Almost Blank Subframe (ABS) and Cell Range Expansion (CRE). To mitigate the cross-tier interference between macro and femtocell, it is important to efficiently combine the ABS and CRE in heterogeneous network. Since it is hard to evaluate the total throughput of heterogeneous network numerically, we evaluate the total throughput by using system level simulation (SLS). As a result of evaluation, the throughputs of many different cases of combination of ABS and CRE are compared.

Joint Operation of ABS with Power Control and Derivation of an Effective ABS Ratio for LTE Hetnet Environments (LTE-A 이종망 환경에서 ABS와 Power Control의 동시적용과 ABS 비율 도출)

  • Sung, No-Hoon;Choi, Young-June;Jang, Ji-Woong
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.40 no.12
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    • pp.2381-2388
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    • 2015
  • It has been known that interference occurs between macrocell ans small-cell base stations in a heterogeneous network (HetNet) of LTE-A. For solving this problem, 3GPP suggested eICIC (Enhanced Inter Cell Interference Coordination) that includes ABS (Almost Blank Subframe) and power control. This paper proposes to use ABS with power control and derives an effective ABS ratio as a function of the number of users and HeNBs. Through simulation, we confirm that integration of ABS and power control can mitigate interference than using ABS only. Furthermore, we verify that an effective ABS ratio is different depending on the number of users and HeNBs.

Transmit Power Allocation for Soft Frequency Reuse in Coordinated Cellular Systems (인접셀간 협력하는 셀룰라 시스템에서 소프트 주차수 재사용을 위한 송신전력할당 기법)

  • Kim, Dong-Hee
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.34 no.4A
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    • pp.316-323
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    • 2009
  • Power allocation of soft frequency reuse(SFR) to increase cell edge user throughput by reducing inter-cell interference is proposed for coordinated cellular systems. SFR is the effective technique to increase cell edge user throughput, however, it costs the degradation of total system throughput. The cost increases when SFR operated in distributed resource controlled systems fails to be fast adaptive in the change of user distribution. The proposed scheme enables coordinated cells to control transmit power adaptively depending on user distribution so that it minimizes the loss of system throughput introduced from SFR while it guarantees enhancement of cell edge user throughput. Through system level simulation considering neighboring two cells, evaluation result for adaptive power allocation is shown compared with static power allocation.

In vivo action of RNA G-quadruplex in phloem development

  • Cho, Hyunwoo;Cho, Hyun Seob;Hwang, Ildoo
    • BMB Reports
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    • v.51 no.11
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    • pp.547-548
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    • 2018
  • Phloem network integrates cellular energy status into post-embryonic growth, and development by tight regulation of carbon allocation. Phloem development involves complicated coordination of cell fate determination, cell division, and terminal differentiation into sieve elements (SEs), functional conduit. All of these processes must be tightly coordinated, for optimization of systemic connection between source supplies and sink demands throughout plant life cycle, that has substantial impact on crop productivity. Despite its pivotal role, surprisingly, regulatory mechanisms underlying phloem development have just begun to be explored, and we recently identified a novel translational regulatory network involving RNA G-quadruplex and a zinc-finger protein, JULGI, for phloem development. From this perspective, we further discuss the role of RNA G-quadruplex on post-transcriptional control of phloem regulators, as a potential interface integrating spatial information for asymmetric cell division, and phloem development.

Synthesis and Photovoltaic Performance of Long Wavelength Absorption Dyes for the Dye Sensitized Solar Cell (장 파장 대 태양광을 흡수하는 염료감응형태양전지에 대한 염료와 합성)

  • Kim, Sangah;Yoon, Jooyoung;Kim, Jaehong
    • 한국신재생에너지학회:학술대회논문집
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    • 2010.06a
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    • pp.89.2-89.2
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    • 2010
  • The dye-sensitized solar cell (DSSC) is a device for the conversion of visible light into electricity, based on the sensitization of wide bandgap semiconductors. The performance of the cell mainly depends on a dye used as sensitizer. The absorption spectrum of the dye and the anchorage of the dye to the surface of $TiO_2$ are important parameters determining the efficiency of the cell. Generally, transition metal coordination compounds(ruthenium polypyridyl complexes) are used as the effective sensitizers, due to their intense charge-transfer absorption in the whole visible range and highly efficient metal-to ligand charge transfer. However, ruthenium polypyridyl complexes contain a heavy metal, which is undesirable from point of view of the environmental aspects. Moreover, the process to synthesize the complexes is complicated and costly. Alternatively, organic dyes can be used for the same purpose with an acceptable efficiency. The advantages of organic dyes include their availability and low cost. We designed and synthesized a series of organic sensitizers containing long wavelength absorption-chromophores for the dye sensitized solar cell. The DSSC composed of Blue-chromophores for the sensitization absorbed long wavelength region which is different also applied into the dye-cocktail (mixing) system. The photovoltaic property of DSSCs organic long wavelength absorption-chromophores were measured and evaluated by comparison with that of individual chromophores.

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Synthesis and Photovoltaic Performance of NIR Absorption Dyes for the Dye Sensitized Solar Cell (NIR 흡수 염료를 이용한 염료감응형 태양전지)

  • Kim, Sangah;Jung, Miran;Lee, Minkyung;Kim, Jaehong
    • 한국신재생에너지학회:학술대회논문집
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    • 2011.05a
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    • pp.118.1-118.1
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    • 2011
  • The dye-sensitized solar cell (DSSC) is a device for the conversion of visible light into electricity, based on the sensitization of wide bandgap semiconductors. The performance of the cell mainly depends on a dye used as sensitizer. The absorption spectrum of the dye and the anchorage of the dye to the surface of TiO2 are important parameters determining the efficiency of the cell. Generally, transition metal coordination compounds(ruthenium polypyridyl complexes) are used as the effective sensitizers, due to their intense charge-transfer absorption in the whole visible range and highly efficient metal-to ligand charge transfer. However, ruthenium polypyridyl complexes contain a heavy metal, which is undesirable from point of view of the environmental aspects. Moreover, the process to synthesize the complexes is complicated and costly. Alternatively, organic dyes can be used for the same purpose with an acceptable efficiency. The advantages of organic dyes include their availability and low cost. We designed and synthesized a series of organic sensitizers containing long wavelength absorption-chromophores for the dye sensitized solar cell. The DSSC composed of Blue-chromophores for the sensitization absorbed long wavelength region which is different also applied into the dye-cocktail (mixing) system. The photovoltaic property of DSSCs organic long wavelength absorption-chromophores were measured and evaluated by comparison with that of individual chromophores.

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Regulation of Intercellular Protein and RNA Movement (생체고분자 단백질 및 RNA의 세포간 이동 조절)

  • Moon, Ju-Yeon;Jung, Jin-Hee;Rim, Yeong-Gil;Datla, Raju;Joliot, Alain;Jackson, David;Kim, Jae-Yean
    • Journal of Plant Biotechnology
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    • v.34 no.2
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    • pp.129-137
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    • 2007
  • Intercellular signaling is a crucial biological process for the coordination of cell differentiation, organ development and whole plant physiology. The intercellular movement of macromolecule signals such as proteins and RNAs has emerged as a novel mechanism of cell-to-cell communication in plant. Plasmodesmata, which are intercellular symplasmic channels, provide a key pathway for cell-to-cell trafficking of regulatory proteins / RNAs. This review specifically focuses on integrating the recent understanding on non-cell autonomous macromolecules, their function and regulatory mechanisms of intercellular trafficking through plasmodesmata.

On the Multiuser Diversity in SIMO Interfering Multiple Access Channels: Distributed User Scheduling Framework

  • Shin, Won-Yong;Park, Dohyung;Jung, Bang Chul
    • Journal of Communications and Networks
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    • v.17 no.3
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    • pp.267-274
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    • 2015
  • Due to the difficulty of coordination in the cellular uplink, it is a practical challenge how to achieve the optimal throughput scaling with distributed scheduling. In this paper, we propose a distributed and opportunistic user scheduling (DOUS) that achieves the optimal throughput scaling in a single-input multiple-output interfering multiple-access channel, i.e., a multi-cell uplink network, with M antennas at each base station (BS) and N users in a cell. In a distributed fashion, each BS adopts M random receive beamforming vectors and then selects M users such that both sufficiently large desired signal power and sufficiently small generating interference are guaranteed. As a main result, it is proved that full multiuser diversity gain can be achieved in each cell when a sufficiently large number of users exist. Numerical evaluation confirms that in a practical setting of the multi-cell network, the proposed DOUS outperforms the existing distributed user scheduling algorithms in terms of sum-rate.