• Title/Summary/Keyword: causes and consequences

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Sciatic neurotmesis and periostitis ossificans progressiva due to a traumatic/unexpected glass injury: a case report

  • Berkay Yalcinkaya;Hasan Ocak;Ahmet Furkan Colak;Levent Ozcakar
    • Journal of Yeungnam Medical Science
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    • v.41 no.1
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    • pp.45-47
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    • 2024
  • Peripheral nerves may be affected or injured for several reasons. Peripheral nerve damage can result from trauma, surgery, anatomical abnormalities, entrapment, systemic diseases, or iatrogenic injuries. Trauma and iatrogenic injuries are the most common causes. The ulnar, median, and radial nerves are the most injured nerves in the upper extremities, while the sciatic and peroneal nerves are the most injured nerves in the lower extremities. The clinical symptoms of peripheral nerve damage include pain, weakness, numbness/ tingling, and paresthesia. Therefore, early diagnosis and appropriate treatment of peripheral nerve injuries are crucial. If a peripheral nerve injury is left untreated, it can lead to severe complications and significant morbidity. The sciatic nerve is one of the most affected nerves. This nerve is generally injured by trauma and iatrogenic causes. Children are more susceptible to trauma than adults. Therefore, sciatic nerve injuries are observed in pediatric patients. When the sciatic nerve is damaged, pain, weakness, sensory loss, and gait disturbances can occur. Therefore, the diagnosis and treatment of sciatic nerve injuries are important to avoid unexpected consequences. Ultrasound can play an important role in the diagnosis of peripheral nerve injury and the follow-up of patients. The aim of this case report is twofold. First, we aimed to emphasize the critical role of ultrasonographic evaluation in the diagnosis of peripheral nerve injuries and pathologies. Second, we aimed to present this case, which has distinguishing features, such as the existence of periostitis ossificans progressiva with sciatic neurotmesis due to a traumatic glass injury.

A Review of Urban Flooding: Causes, Impacts, and Mitigation Strategies (도시 홍수: 원인, 영향 및 저감 전략 고찰)

  • Jin-Yong Lee
    • The Journal of Engineering Geology
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    • v.33 no.3
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    • pp.489-502
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    • 2023
  • Urban floods pose significant challenges to cities worldwide, driven by the interplay between urbanization and climate change. This review examines recent studies of urban floods to understand their causes, impacts, and potential mitigation strategies. Urbanization, with its increase in impermeable surfaces and altered drainage patterns, disrupts natural water flow, exacerbating surface runoff during intense rainfall events. The impacts of urban floods are far-reaching, affecting lives, infrastructure, the economy, and the environment. Loss of life, property damage, disruptions to critical services, and environmental consequences underscore the urgency of effective urban flood management. To mitigate urban floods, integrated flood management strategies are crucial. Sustainable urban planning, green infrastructure, and improved drainage systems play pivotal roles in reducing flood vulnerabilities. Early warning systems, emergency response planning, and community engagement are essential components of flood preparedness and resilience. Looking to the future, climate change projections indicate increased flood risks, necessitating resilience and adaptation measures. Advances in research, data collection, and modeling techniques will enable more accurate flood predictions, thus guiding decision-making. In conclusion, urban flooding demands urgent attention and comprehensive strategies to protect lives, infrastructure, and the economy.

Stereological study of testes following experimentally-induced unilateral cryptorchidism in rats

  • Javad Sadeghinezhad;Fatemeh Yarmahmoudi;Mohammad Mehdi Dehghan;Saeed Farzad Mohajeri;Ehsan Roomiani;Hadis Bojarzadeh;Mahdi Aghabalazadeh Asl;Ava Saeidi;Margherita De Silva
    • Clinical and Experimental Reproductive Medicine
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    • v.50 no.3
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    • pp.160-169
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    • 2023
  • Objective: Cryptorchidism is one of the main causes of infertility and can result in testicular cancer. This study aimed to present quantitative data on the damage caused by cryptorchidism using stereological analysis. Methods: Thirty newborn rats were randomly divided into control and experimental groups. The experimental group underwent surgery to induce unilateral cryptorchidism in the left testis, whereas the control group underwent a sham surgical procedure 18 days after birth. The testes were removed at designated time points (40, 63, and 90 days after birth) for stereological evaluation and sperm analysis. Total testicular volume, interstitial tissue volume, seminiferous tubule volume and length, and seminiferous epithelium volume and surface area were measured. Other parameters, such as sperm count, sperm morphology, and sperm tail length, were also examined. Results: Statistically significant differences (p<0.05) were observed between the experimental and the control groups at different ages regarding the volumes of various parameters, including the surface area of the germinal layer, the length of the seminiferous tubules, sperm count, and sperm morphology. However, no significant differences were observed in the epithelial volume and the sperm tail length of the groups. Conclusion: Given the substantial effect of cryptorchidism on different testicular parameters, as well as the irreversible damage it causes in the testes, it is important to take this abnormality seriously to prevent these consequences.

Male Infertility in the Era of ICSI (ICSI시대에서의 남성불임)

  • Seo, Ju-Tae
    • 대한생식의학회:학술대회논문집
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    • 2003.12a
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    • pp.21-30
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    • 2003
  • As a result of the technological advance provided by intracytoplasmic sperm injection (ICSI) in 1992, the evaluation and treatment of the infertile male has changed significantly. Many men who were previously thought to be irreversibly infertile have the potential to initiate their own biologic pregnancy. However, not all men having impaired semen parameter are ideal candidates for ICSI for numerous reasons including a lack of addressing the underlying problem causing the male infertility, unknown genetic consequences, and cost-effectiveness issues. In this era of ICSI, the fundamental approach to the male with suspected subfertility is unchanged and is based on a history, physical examination, and focused laboratory testing. The urologist should approach the patient with an intent to identify remediable causes of subfertility given the specific clinical situation. For instance, should a gentleman have his varicocele repaired or vasectomy reversed, or should he proceed directly with ICSI? If no factors can be improved in a timely manner, then ICSI should be considered using the available sperm. Examples of recent advances include the diagnosis and treatment of ejaculatory duct obstruction, indications and techniques for performing testis biopsy, and technique for sperm harvesting. In addition, potential genetic causes of male subfertility should be diagnosed and discussed with the patient. Cystic fibrosis gene mutation, karyotype abnormallities, and Y-chromosome microdeletions all have recently been identified as causative for male infertility in otherwise phenotypically normal men. With recently evolved diagnostic and therapeutic techniques now available for the infertile couple, even the most severe male factor problems in patients previously considered irreversibly infertile are now potentially treatable. The physician should be aware of the availability and limitations of these new and exciting reproductive technologies because they will allow him to provide timely and more effective therapy for the infertile couple. An understanding of these advances by all physicians is important as we progress into the $21^{st}$ century

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Study on Risk Assessment Method of Hydrogen Station using FAHP-HAZOP (FAHP-HAZOP을 적용한 수소충전소의 위험성평가 방법 연구)

  • Yeong Gwang Jo;Sien Ho Han
    • Journal of the Korean Institute of Gas
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    • v.27 no.4
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    • pp.92-101
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    • 2023
  • To solve the problem of climate change, carbon neutrality has now become a necessity rather than an option. Hydrogen is not only a energy storage that can supplement the intermittent production of renewable energy, but is also considered a good alternative in the field of utilization as it does not emit carbon dioxide after reaction. In order to revitalize hydrogen vehicles, one of the fields of hydrogen utilization, the construction of hydrogen station infrastructure must be preceded. Prioritization of risk factors is necessary for efficient operation and risk assessment of hydrogen stations, but due to the short operation period of domestic hydrogen stations, there is a lack of frequency data on accidents and their reliability is low. In this study, we aim to identify the causes and consequences of deviations in hydrogen stations through HAZOP analysis. Additionally, we intend to analyze them using Fuzzy-AHP. Through this, we intend to derive the decision values for the causes of deviations in hydrogen stations and apply them to hydrogen accident cases and risk assessments to confirm the reliability and utility of the data.

Chronic administration of ketamine ameliorates the anxiety- and aggressive-like behavior in adolescent mice induced by neonatal maternal separation

  • Shin, Sang Yep;Baek, Nam Jun;Han, Seung Ho;Min, Sun Seek
    • The Korean Journal of Physiology and Pharmacology
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    • v.23 no.1
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    • pp.81-87
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    • 2019
  • Ketamine has long been used as an anesthetic agent. However, ketamine use is associated with numerous side effects, including flashbacks, amnesia, delirium, and aggressive or violent behavior. Ketamine has also been abused as a cocktail with ecstasy, cocaine, and methamphetamine. Several studies have investigated therapeutic applications of ketamine, demonstrating its antidepressant and anxiolytic effects in both humans and rodents. We recently reported that neonatal maternal separation causes enhanced anxiety- and aggressive-like behaviors in adolescent. In the present study, we evaluated how acute and chronic ketamine administration affected the behavioral consequences of neonatal maternal separation in adolescent mice. Litters were separated from dams for 4 hours per day for 19 days beginning after weaning. Upon reaching adolescence (post-natal day 35-49), mice were acutely (single injection) or chronically (7 daily injections) treated with a sub-anesthetic dose (15 mg/kg) of ketamine. At least 1 h after administration of ketamine, mice were subjected to open-field, elevated-plus maze, and resident-intruder tests. We found that acute ketamine treatment reduced locomotor activity. In contrast, chronic ketamine treatment decreased anxiety, as evidenced by increased time spent on open arms in the elevated-plus maze, and remarkably reduced the number and duration of attacks. In conclusion, the present study suggests that ketamine has potential for the treatment of anxiety and aggressive or violent behaviors.

Enhanced reasoning with multilevel flow modeling based on time-to-detect and time-to-effect concepts

  • Kim, Seung Geun;Seong, Poong Hyun
    • Nuclear Engineering and Technology
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    • v.50 no.4
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    • pp.553-561
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    • 2018
  • To easily understand and systematically express the behaviors of the industrial systems, various system modeling techniques have been developed. Particularly, the importance of system modeling has been greatly emphasized in recent years since modern industrial systems have become larger and more complex. Multilevel flow modeling (MFM) is one of the qualitative modeling techniques, applied for the representation and reasoning of target system characteristics and phenomena. MFM can be applied to industrial systems without additional domain-specific assumptions or detailed knowledge, and qualitative reasoning regarding event causes and consequences can be conducted with high speed and fidelity. However, current MFM techniques have a limitation, i.e., the dynamic features of a target system are not considered because time-related concepts are not involved. The applicability of MFM has been restricted since time-related information is essential for the modeling of dynamic systems. Specifically, the results from the reasoning processes include relatively less information because they did not utilize time-related data. In this article, the concepts of time-to-detect and time-to-effect were adopted from the system failure model to incorporate time-related issues into MFM, and a methodology for enhancing MFM-based reasoning with time-series data was suggested.

Proposal for an Evaluation Method for the Performance of Work Procedures

  • Mohammed, Mouda;Mebarek, Djebabra;Wafa, Boulagouas;Makhlouf, Chati
    • Safety and Health at Work
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    • v.7 no.4
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    • pp.299-306
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    • 2016
  • Background: Noncompliance of operators with work procedures is a recurrent problem. This human behavior has been said to be situational and studied by many different approaches (ergonomic and others), which consider the noncompliance with work procedures to be obvious and seek to analyze its causes as well as consequences. Methods: The object of the proposed method is to solve this problem by focusing on the performance of work procedures and ensuring improved performance on a continuous basis. Results: This study has multiple results: (1) assessment of the work procedures' performance by a multicriteria approach; (2) the use of a continuous improvement approach as a framework for the sustainability of the assessment method of work procedures' performance; and (3) adaptation of the Stop-Card as a facilitator support for continuous improvement of work procedures. Conclusion: The proposed method emphasizes to put in value the inputs of continuous improvement of the work procedures in relation with the conventional approaches which adopt the obvious evidence of the noncompliance to the working procedures and seek to analyze the cause-effect relationships related to this unacceptable phenomenon, especially in strategic industry.

Byron's Don Juan VII-VIII: Characters' Diverse Attitudes toward Glory through War

  • Yu, Jie-Ae
    • Journal of English Language & Literature
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    • v.56 no.3
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    • pp.429-443
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    • 2010
  • The purpose of this article is to examine how Byron's Don Juan VII-VIII depicts the various facets of characters' minds and actions in taking attitude toward glory during wartime in Ismail, Turkey. It explores the multifaceted sides of their hidden intentions and military activities in the self-centered and ruthless battle. Byron investigates their diverse and unreasonable causes, which drive them to undertake their particular deeds while participating in the combat. He unfolds the complex, dark layers of man's motivations and acts in responding to such martial ideals as fame, honor, success, or triumph. By making an effective characterization of four major figures such as Suwarrow, Juan, Johnson, and the Turkish Khan, Byron, indeed, enriches the poem with a variety of their different conceptions and stances toward these remarkable achievements. While fighting in the same battle, they, interestingly, reveal strikingly different attitudes, especially in responding to the complex aspects of reputation, glory, war, manliness or fate. The article also considers how the two Cantos of Don Juan feature the ironic results of the characters' quest for glory, which bring about an extensive range of inhuman consequences. The poet accentuates the diverse, negative aftermaths of their illusionary, abusive pursuit of fame and honor. In doing so, he effectively utilizes figurative portrayals of brutal pictures to highlight the unanticipated boundaries and dreadful outcomes, which have been caused by the undesirable or irrational exercises of their freedom of choice in pursuing such self-centered desires and renown.

Evaluation of the role of Lactobacillus casei on alcohol metabolism and liver functions of rats

  • Kim, Ji-Hyun;Kim, Hyun-Jin;Kim, Sung-Koo
    • 한국생물공학회:학술대회논문집
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    • 2003.10a
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    • pp.214-218
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    • 2003
  • Alcohol consumption causes numerous consequences on the health of the human body. Heavy drinking on a daily base has caused liver diseases. Furthermore, some products such as acetaldehyde produced from alcohol metabolism are more toxic than alcohol itself. This study was carried out to evaluate the role of Lactobacillus casei on alcohol metabolism, especially, the removal of the toxic effect of alcohol. The maximum alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities from L. casei were observed at 4 hr of culture. L. casei was confirmed to produce the ADH and ALDH by the SDS-PAGE. From in vivo test using SD rats with 22% alcoholic drink, blood alcohol concentration (BAC), glutamic oxaloacetic transaminase (GOT) and glutamic pyruvic transaminase (GPT) of the rats feeding the medium containing L. casei were lower than those of the rats feeding the medium containing an alcoholic drink only This demonstrates that the ADH and ALDH produced by L. casei have virtual functions to detoxicate the alcohol in vivo and the fermentation broth of L. casei can be used as an alcohol detoxification drink.

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