• Journal of Family Resource Management and Policy Review
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• v.19 no.3
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• pp.17-40
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• 2015

The purpose of this study was to analyze the in-home child care support service experience of twenty child rearing families. In order to conduct this study, grounded theory method was employed. The central phenomenon of the service experience digged out from this study was 'difficulty' (i. e. insecurity and a feeling of helplessness). The causal conditions which brought about the central phenomenon were 'defect of system' and 'service characteristics' The intervening conditions included 'alternative resources' 'working conditions' and 'service institute manager discretion'. The contextual conditions consisted of 'maternal ideology' 'the public nanny's personality awareness'. The action/interaction strategies on the central phenomenon were 'inaction' 'insecurity decrease strategy' and 'dissonance decrease strategy. The final outcome was 'rearing gap fillup "the method of nanny managing" dissatisfaction accumulation' ''system improvement demand'. The families were classified as four types: 'management/subject' 'adaptation/dependent' 'patience/acceptant' 'supplementation/overcoming'. Based on these results, this study provided a few political and practice suggestions to improve this system.

• Journal of Distribution Science
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• v.15 no.3
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• pp.27-37
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• 2017

Purpose - The current study analyzes the effect of business startup education on business startup education satisfaction and entrepreneurial intention. Also, it attempts to discover if business startup confidence plays a moderating role between business startup education satisfaction and entrepreneurial intention. Research design, data, and methodology - The survey was conducted for approximately 60 days, from July 20, 2016 to September 20, 2016, and distributed to 300 restaurant founders who started their business through business startup education provided by Korea Food Service Industry Association in Seoul, Kyungki and Incheon or existing business founders. Results - Per multiple regression analysis of business startup education and business startup education satisfaction, among business startup education, all law, entrepreneurship, commercial power analysis, and practical education have significantly positive effect. Per simple regression analysis of business startup education satisfaction and entrepreneurial intention, business startup education has significantly positive effects on entrepreneurial intention. Business startup education satisfaction and business startup confidence interaction show that they do not have a moderating role between business startup education satisfaction and entrepreneurial intention. Conclusions - Setting up theoretical reasoning, this study supports conclusions drawn by prior studies: business startup education has significantly positive effects on business startup education satisfaction and entrepreneurial intention.

• Journal of Korean Academy of Nursing
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• v.32 no.5
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• pp.694-705
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• 2002

The purpose of this study is to describe the health behavior experience of middle-aged Korean women in rural areas, and to help understand their health practice, perceive their nursing needs and provide guidelines to developing appropriate nursing interventions. Method: The participants were 18 healthy middle-aged women living in rural areas, with no serious illness that require hospitalization. The data was collected through interviews and participant observation, analyzed by the grounded theory methodology of Strauss & Corbin(1997). The data collection period was from April to November of 2001. Result: Depending on the paradigm model, the central phenomenon was family-oriented pursuing of yangsaeng. The causal condition was less confidence on one's own health, responsibilities in caring for family. The contexts were cultural system. The intervening condition was information system, support system, limitation of approaching a medical institution. The action/ interaction strategies were yangsaeng through dietary practice, yangsaeng through promoting clothing and housing, yangsaeng through exercise, practice of folk therapy, yangsaeng through mental hygiene, and use of medical institution. The consequences were stabilization of body and mind, and stabilization of family. Conclusion: It is recommended for nurses to understand health behavior experience of middle-aged women, and provide nursing intervention with theoretical scheme and practical principles so that these women can pursue the family-oriented process of yangsaeng.

• Journal of Korean Academy of Nursing
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• v.46 no.6
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• pp.858-870
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• 2016

Purpose: The purpose of the study was to explore and describe the adaptation process of older people to group homes. Methods: Participants were twenty older adults aged 65 or older who were living in group homes. Data were collected from January to April, 2015. In-depth unstructured interviews were conducted with individual participants. Data were analyzed using Strauss and Corbin's grounded theory method. Results: From open coding, 100 concepts, 38 sub-categories, and 14 categories were identified. Analysis showed that the central phenomenon of the adaptation process of older people to group homes was 'gradually giving up'. Causal conditions were 'good-for-nothing body', contextual conditions were 'pushed', 'beleaguered'. Intervening conditions were 'reliable pillar: children', 'having affection (情) more than having it from family: facility workers', 'comfort - like feeling at home', 'relieved: system'. Action/interaction strategies were 'facing the unfamiliar reality', 'building relationships with other people', 'accepting reality'. Consequences were 'a good place, more than expected', 'hope for the remaining days', 'waiting for a peaceful death'. Conclusion: The results of this study provide an in-depth understanding of the experience of the adaptation process of older people to group homes. The findings from this study can be used as basic data to establish policies to increase the number of small scale facilities which can help older adults adapt easily to the facilities.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.25 no.3
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• pp.185-196
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• 2018

Purpose: The purpose of this study was to investigate the alopecia experience in adults and to explain the process of their experiences. Methods: Using a grounded theory methodology, 18 interviews were performed with fourteen men and four women, 34~57 years of age, suffering from alopecia. Data were analyzed using the constant comparative analysis method. Results: The core category emerged as "inescapable fetters". adults with alopecia engaged in three stages: embarrassment, seeking solution, and acceptance phase. Causal conditions were a vicious cycle of stress, biological factors and poor life style. Contextual conditions were recognition of irreversibleness, negative social awareness, and marriage. The central phenomenon of the adaptation process among the adults with alopecia was withdrawn life due to negative body image. Action/Interaction strategies included rely on medical treatment, efforts to take good care of hair, research for information treatment, efforts to cover up hair loss, and mind control. Intervening conditions were time cost, economic cost, support of surrounding people. Consequences was burden of unfinished lifetime homework. Conclusion: When caring for these adults, it is important to identify needs, allow patients to express what they want at that moment and support them in maintaining a daily life.

• Asian Journal of Business Environment
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• v.11 no.4
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• pp.17-29
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• 2021

Purpose: The aim of this study is to explore the dynamic linkage between conditional stock market volatility and macroeconomic uncertainty of Bangladesh. Research design, data, and methodology: This study uses monthly data covering the time period from January 2005 to December 2018. A comprehensive set of macroeconomic variables, namely industrial production index (IP), consumer price index (CPI), broad money supply (M2), 91-day treasury bill rate (TB), treasury bond yield (GB), exchange rate (EX), inflow of foreign remittance (RT) and stock market index of DSEX are used for analysis. Symmetric and asymmetric univariate GARCH family of models and multivariate VAR model, along with block exogeneity and impulse response functions, are implemented on conditional volatility series to discover the possible interactions and causal relations between macroeconomic forces and stock return. Results: The analysis of the study exhibits time-varying volatility and volatility persistence in all the variables of interest. Moreover, the asymmetric effect is found significant in the stock return and most of the growth series of macroeconomic fundamentals. Results from the multivariate VAR model indicate that only short-term interest rate significantly influence the stock market volatility, while conditional stock return volatility is significant in explaining the volatility of industrial production, inflation, and treasury bill rate. Conclusion: The findings suggest an increasing interdependence between the money market and equity market as well as the macroeconomic fundamentals of Bangladesh.

• Research in Community and Public Health Nursing
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• v.32 no.4
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• pp.506-517
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• 2021

Purpose: The purpose of this study was to explore the health management experience of Vietnamese Married Immigrant Women living in the city. Methods: The study participants were 11 Vietnamese immigrant women residing in the urban area who felt bad about their health. Data collection was conducted in depth through individual interviews, and the collected data were analyzed through Strauss & Corbin data analysis. Results: The core category was "health is not a necessity but a choice in a strange land called Korea". The contextual conditions were, "The hard thing-exposing "myself" to the world", and "Hurts hidden, to be away from people's eyes". For the causal condition, the categories of "Unfamiliar life to live alone", "Unfamiliar life different from expectation", and "Symptoms of body suddenly suffering alone", were derived. Through action-interaction, the immigrant women revealed that in their Korean social-structural context, they tended to follow "Health pushed away in turbulent life". The intervening conditions were "a person who is able to help me", "places that can give a helping hand nearby", and "Vietnamese women's grit". A Vietnamese married immigrant woman had her own "Health in the chain with life". As a result, they gained "Health, which is a top priority in life" or "Health oppressed by the weight of life". Conclusion: This study enhanced the understanding of the healthcare process of Vietnamese married immigrant women living in urban areas.

• Genomics & Informatics
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• v.20 no.1
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• pp.8.1-8.14
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• 2022

Despite the success of recent genome-wide association studies investigating longitudinal traits, a large fraction of overall heritability remains unexplained. This suggests that some of the missing heritability may be accounted for by gene-gene and gene-time/environment interactions. In this paper, we develop a Bayesian variable selection method for longitudinal genetic data based on mixed models. The method jointly models the main effects and interactions of all candidate genetic variants and non-genetic factors and has higher statistical power than previous approaches. To account for the within-subject dependence structure, we propose a grid-based approach that models only one fixed-dimensional covariance matrix, which is thus applicable to data where subjects have different numbers of time points. We provide the theoretical basis of our Bayesian method and then illustrate its performance using data from the 1000 Genome Project with various simulation settings. Several simulation studies show that our multivariate method increases the statistical power compared to the corresponding univariate method and can detect gene-time/ environment interactions well. We further evaluate our method with different numbers of individuals, variants, and causal variants, as well as different trait-heritability, and conclude that our method performs reasonably well with various simulation settings.

• BMB Reports
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• v.55 no.5
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• pp.238-243
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• 2022

Autism or autism spectrum disorder (ASD) is a behavioral syndrome characterized by persistent deficits in social interaction, and repetitive patterns of behavior, interests, or activities. The gene encoding Methyl-CpG binding protein 2 (MeCP2) is one of a few exceptional genes of established causal effect in ASD. Although genetically engineered mice studies may shed light on how MeCP2 loss affects synaptic activity patterns across the whole brain, such studies are not considered practical in ASD patients due to the overall level of impairment, and are technically challenging in mice. For the first time, we show that hippocampal MeCP2 knockdown produces behavioral abnormalities associated with autism-like traits in rats, providing a new strategy to investigate the efficacy of therapeutics in ASD. Ketamine, an N-Methyl-D-aspartate (NMDA) blocker, has been proposed as a possible treatment for autism. Using the MeCP2 knockdown rats in conjunction with a rat model of valproic acid (VPA)-induced ASD, we examined gene expression and ASD behaviors upon ketamine treatment. We report that the core symptoms of autism in MeCP2 knockdown rats with social impairment recovered dramatically following a single treatment with ketamine.

• The Journal of Korean Academic Society of Nursing Education
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• v.28 no.1
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• pp.15-26
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• 2022

Purpose: The purposes of this study was to describe the lived experience structures of married immigrant women with chronic diseases in reorganizing their lives in a variety of situations and contexts. Methods: This study applied grounded theory approach, and the participants were 15 married immigrant women with chronic disease. Data were collected through individual in-depth interviews and then analyzed by the method in Strauss and Corbin (1998). Results: The extracted data were organized 41 concepts, 21 subcategories, and 8 categories. The central phenomenon was determined to be "Life turned into a chronic disease." The causal conditions were "Undergoing physical and mental stress from marriage", "Lack of information on chronic diseases." The extracted contexts was "The demand for health resources." action and interaction strategies, "Finding problems and solutions." The intervention conditions influencing the strategies was "Establishing a support system." The result of such action was "To settle down in a way of life that suits your conditions." Conclusion: By providing a comprehensive and integrative understanding of how married immigrant women with chronic disease reorganize their lives, the study is expected to contribute to the development of social systems and national policies.