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Cost-Sensitive Case Based Reasoning using Genetic Algorithm: Application to Diagnose for Diabetes

  • Park Yoon-Joo;Kim Byung-Chun
    • 한국지능정보시스템학회:학술대회논문집
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    • 한국지능정보시스템학회 2006년도 춘계학술대회
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    • pp.327-335
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    • 2006
  • Case Based Reasoning (CBR) has come to be considered as an appropriate technique for diagnosis, prognosis and prescription in medicine. However, canventional CBR has a limitation in that it cannot incorporate asymmetric misclassification cast. It assumes that the cast of type1 error and type2 error are the same, so it cannot be modified according ta the error cast of each type. This problem provides major disincentive to apply conventional CBR ta many real world cases that have different casts associated with different types of error. Medical diagnosis is an important example. In this paper we suggest the new knowledge extraction technique called Cast-Sensitive Case Based Reasoning (CSCBR) that can incorporate unequal misclassification cast. The main idea involves a dynamic adaptation of the optimal classification boundary paint and the number of neighbors that minimize the tatol misclassification cast according ta the error casts. Our technique uses a genetic algorithm (GA) for finding these two feature vectors of CSCBR. We apply this new method ta diabetes datasets and compare the results with those of the cast-sensitive methods, C5.0 and CART. The results of this paper shaw that the proposed technique outperforms other methods and overcomes the limitation of conventional CBR.

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Al-Cu첨가(添加)에 의(依)한 CV흑연주철(黑鉛鑄鐵)에 관한 기초연구 (A Study of the CV graphite cast iron with small additions of a Al-Cu alloy)

  • 전형탁;허보영;김수영
    • 한국주조공학회지
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    • 제3권4호
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    • pp.239-247
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    • 1983
  • CV graphite cast iron has been studied and generally known to have properties close to the average values of those between flake and spheroidal graphite cast iron. However, the thermal diffusivity of CV graphite cast iron is much larger than that of the average value of those between flake and spheroidal graphite cast iron. In this study, an easy production method of CV graphite cast iron with small additions of a Al-Cu which is known as the element of the graphitization was investigated. The effects of hold time and of Al-Cu additions after the treatments with spheroidizer (Fe-Si-Mg alloy) were also investigated. Increasing the additions of a Al-Cu alloy, the holding time to form a CV graphite cast iron was decreasing. Tensile strength and thermal diffusivity (flash method) were measured in order to find the changes of the mechanical properties and the physical properties. Spheroidal, CV, and flake graphite cast iron have tensile strengths 46.44, 38.29, and $27.29\;kg/mm^2$ and thermal diffusivities $3.95{\times}10^{-6,}$ $8.41{\times}10^{-6}$, $8.81{\times}10^{-6}m^2/sec$, respectively at room temperature.

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한우분내에 인의 첨가가 지렁이의 생육과 분립생산량에 미치는 영향 (Effect of supplementing phosphorus to Korean cow manure on the growth and cast production of earthworm (Eisenia foetida))

  • 이주삼;이필원
    • 한국축산시설환경학회지
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    • 제7권2호
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    • pp.127-136
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    • 2001
  • This experiment was carried out to investigate the effect of supplementing phosphorus to Korean cow manure on the growth and cast production of earthworm(Eisenia Foetida), and to estimate the optimal phosphorus level for the growth and cast production of earthworm and ratios of available phosphorus and calcium content of cast in optimal phosphorus levels. Phosphorus supplementing ratios to Korean native cow were 0, 1%, 2%, 4% and 8A%, respectively. The volume of raising box was 3375cm$^3$(15$\times$15$\times$15cm), and 500g of cow manure filled up to 10cm layer. Raising density was 90㎤ per worm during the experimental period(60 days). The maximum fresh weight and cast production of earthworm were obtained at 2~4% and 1% levels of phosphorus supplementation to Korea native cow manure. The total phosphorus and available phosphorus contents of earthworm tissues were not significant among in all treatments. There was a positive significantly differences between total phosphorus and available phosphorus of cast and residual matters. Available phosphorus content of cast were ranged from 9.3mg/g to 17.3mg/g at 1~4% levels of phosphorus supplementation. Ratios of available phosphorus and calcium contents of cast were 1.94~3.15:1 and 0.87~1.33:1 at 2~4% and 0~1% levels of phosphorus supplementation.

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연결방법에 따른 주조체 변위에 관한 3차원적 비교연구 (THREE-DIMENSIONAL COMPARISON OF FRAMEWORK DISPLACEMENTS JOINED BY VARIOUS CONNECTION TECHNIQUES)

  • 임장섭;전영찬;정창모
    • 대한치과보철학회지
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    • 제37권3호
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    • pp.358-374
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    • 1999
  • This study measured the relative displacements of the five-unit fixed partial dentures as cast with the same fixed partial dentures sectioned and assembled by investment-soldering, solder-ing stand-soldering, and cast-joining techniques A total of fifteen specimens using a type IV gold alloy were one-piece cast as control and then sectioned and assembled five test specimens for each method were prepared. A computerized three dimensional coordinate measuring machine and specially designed cylinder for this study were used. Displacement was defined by six displacement variables for the each of cylinders incorporated in each casting: three component displacements(${\Delta}Lx,\;{\Delta}Ly,\;and\;{\Delta}Lz$) and rotational displacements(${\Delta}{\theta}x,\;{\Delta}{\theta}y,\;{\Delta}{\theta}z$). The global displacement was computed using the mathematical formula ${\Delta}R$ = Global displacement =$\sqrt{{(x'-x)}^2+{(y'-y)}^2+{(z'-z)}^2}$ Under the conditions of this study, the following conclusions were drawn: 1. The investment-soldering group showed the largest mean value of final global displacements, followed by stand-soldering group, cast-joining group and one-piece cast group. However, between the mean values of final global displacement for the cast-joining group and one-piece cast group, there was no significant difference. 2. For investment-soldering and stand-soldering groups, the greater global displacements were recorded in soldering phase than in indexing or investing phase. 3. For one-piece cast group, the displacements occured mostly in the casting phase. And for cast-joining group, there was no significant difference in global displacements among the fabricating procedures. 4. Intercentroidal distance decreased in framework-patterning, solder-indexing, solder-standing, and soldering phases, but increased in investment block-investing and casting phases. 5 Specially designed cylinder for touch-trigger type coordinate measuring machine was validated.

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Mapping of the Porcine Calpastatin Gene and Association Study of Its Variance with Economic Traits in Pigs

  • Choi, B.H.;Lee, J.S.;Jang, G.W.;Lee, H.Y.;Lee, J.W.;Lee, K.T.;Chung, H.Y.;Park, H.S.;Oh, S.J.;Sun, S.S.;Myung, K.H.;Cheong, I.C.;Kim, T.H.
    • Asian-Australasian Journal of Animal Sciences
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    • 제19권8호
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    • pp.1085-1089
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    • 2006
  • The objectives of this study were to confirm a location of the calpastatin (CAST) gene in chromosome 2 and to detect associations of genetic variations with economic traits in the porcine CAST gene as a candidate gene for growth and meat quality traits in pigs. Calpastatin is a specific endogenous inhibitor of calpains. The calpain protease system is ubiquitous, and is involved in numerous growth and metabolic processes. Three single nucleotide variations were identified within a 1.6 kb fragment of the porcine CAST gene and these polymorphisms were used for genetic linkage mapping. Linkage and QTL mapping were performed with the National Livestock Research Institute (NLRI) reference families using eight microsatellites and SNP makers in the CAST gene. The porcine CAST gene was mapped adjacent to the markers, SW395 and SW1695 on SSC2 with LOD scores of 15.32 and 8.50, respectively. According to the QTL mapping, a significant association was detected at 82 cM between SW395 and CAST-Hinf I for weight at the age of 30 weeks. In addition, an association study was performed with the $F_2$ animals of NLRI reference families for Hinf I, Msp I and Rsa I polymorphisms in the CAST gene. Two polymorphisms, CAST-Rsa I and CAST-Hinf I, showed significant correlation for growth traits at p<0.01 and p<0.05, respectively.

알루미늄 주조/단조 공정에서 주조조직 제어에 관한 연구 (A Study on the Control of Cast Microstructure in the Aluminum Casting/Forging Process)

  • 배원병;강정윤;이영석;이성모;홍창호
    • 한국정밀공학회지
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    • 제16권9호
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    • pp.41-47
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    • 1999
  • The scale of dendritic structure of a cast preform plays a key role in determining the mechanical properties of cast/forged products. In this study, casting experiments are carried out to reduce dendrite arm spacing (DAS) to smaller than 20 ${\mu}$m by increasing cooling rate of the mold and then to spheriodize dendritic structures by addition of alloying elements such as Zr and Ti-B. From the casting experiments, appropriate casting conditions for producing the cast preform of a motorcycle connecting rod are obtained. To obtain fine microstructures of the cast preform, mold temperature must set to be low whilst cooling rate being high. When cooling rate is 10 $^{\circ}C$/s, the size of DAS is 17.4 ${\mu}$m. And the degree of spheriodization of a grain in the cast preform is described by aspect ratio, which is defined as the ratio of major and minor radii of an elliptical grain. When 0.5% Zr and 0.24 % Ti+B are added to the molten aluminum alloy, the best aspect-ratio 0.75 is obtained. After forging the cast preform of a motorcycle connecting rod, the microstructure and mechanical properties of the cast preform are compared with those of the cast/forged product. Cast/forged products are superior in microstructure and in mechanical properties such as ultimate strength, elongation, and hardness.

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한우(Bos taurus coreanae)의 CAST 유전자 내 변이지역 탐색 및 경제형질과의 연관성 분석 (Identification of Polymorphisms in CAST Gene Associated with Economic Traits in Hanwoo (Bos taurus coreanae))

  • 오재돈;이진아;이건우;박경도;조병욱;전광주;이학교;공홍식
    • 생명과학회지
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    • 제20권10호
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    • pp.1498-1504
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    • 2010
  • Calpastatin (CAST)은 calpain의 억제제 역할을 하는 유전자이며 BTA7에 위치하고 있다. Calpain을 억제하는 CAST 유전자 내 다형성이 육질의 연도에 영향을 미치고 있는 것이 알려져 있다. 또한 여러 연구를 통해 calpain 시스템은 일반 골격근의 성장에 중요한 역할을 하는 것으로 보고되었다. 따라서 본 연구는 한우 집단의 CAST 유전자 내 변이 지역을 탐색하여 경제형질과의 연관성을 분석하기 위하여 실시하였다. CAST 유전자(Accession no. NC_007305) 단일염기변이지역을 탐색 결과 총 5개의 변이(109749T/C, 116151G/A, 109737G/A, 109823T/C, 109926G/A) 지역이 탐색 NCBI에 등록되어 있지 않은 새로운 변이로 본 연구를 통해 탐색되었다. 한우집단 내에서 탐색된 총 5개의 SNP를 대상으로 연관불균형(LD, Linkage disequilibrium) 분석을 수행하였다. 변이들 간의 연관불균형(LD) 정도가 가장 낮은 수준에 있는 2개의 변이지역(109926G/A와 116151G/A, $r^2$=0.038)을 대상으로 경제형질과의 연관성 분석을 실시한 결과 등심단면적(109926G/A, p<0.05)과 18개월령 체중(116151G/A, p<0.05)에서 유의적인 연관성이 검출 되었다. CAST유전자는 도축 후 숙성과정에서 고기의 연도를 증가시키는데 영향을 미칠 뿐만 아니라 가축의 성장에도 깊은 연관성이 있으며, 본 연구를 통해 CAST 유전자 내 변이는 성장 관련 형질과의 연관성이 유의적인 것으로 확인되었다.

고 Cr 주철계 육성용접부의 연삭(abrasion)마모 특성에 대한 연구 (Abrasive wear characteristics of high Cr cast iron hardfacing)

  • 이형근
    • Journal of Welding and Joining
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    • 제15권4호
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    • pp.154-165
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    • 1997
  • Abrasive wear characteristics of high Cr white cast iron-based hardfacing were investigated using the rubber wheel abrasion wear test method according with the ASTM G65-85. Mild steel was also tested for comparison with high Cr cast iron hardfacing. Wear experiments, where the applied force, wheel revolution rate and abrasive powder feed rate were selected as test valuables, were planned and analyzed by response surface method to evaluate wear statistically and quantitatively. Weight loss of high Cr cast iron hardfacing was mostly affected by the applied force and wheel revolution rate, and little by the powder feed rate. Weight loss of mild steel was greatly affected by the wheel revolution rate and powder feed rate, and slowly and steadily increased with the applied force. Abrasive wear mechanism of high Cr cast iron and mild steel was discussed in the light of the wear test results.

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토양상에 의한 Trichloroethyene처리에 관한 연구 (A Study on Control of Trichloroethyene by Soil bed)

  • 이혜령;고경숙;임경택
    • 한국환경보건학회지
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    • 제24권3호
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    • pp.41-47
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    • 1998
  • The purpose of this research is evaluation of adsorption capacity of the cast for TCE comparing with the yellow clay. Furthermore, the experimental data was fitted with the Langmuir and Freundlich isotherm and was found to be apllicable to the adsorption isotherm equation. The soil bed reactor used in this study was made of glass(10 cm in diameter, 100 cm in depth). The cast and yellow clay used as adsorbents were screened with 8-20 mesh mecanically. Results from Equilibrium test with adsorbents showed that the equibrium time of the cast and yellow clay was 9min independent of the amount of the adsorbents. The adsorption efficiencys of the cast and yellow clay for TCE was 66.3% and 56.2%, respectively. In the application of Freundlich isotherm, 1/n of the cast and yellow clay were 0.786 and 0.704, respectively. These results showed that the cast was more available than the yellow clay as TCE adsorbent. The best adsorption capacity was showed at 0% moisture content, 70 ppm inlet concentration and 25$^{\circ}$C temperature.

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주조/단조 기술을 이용한 알루미늄 Lower Control Arm 제조에 관한 연구 (A Study on the Manufacture of Lower Control Arm by Casting/Forging Process)

  • 유민수;권오혁;배원병
    • 한국소성가공학회:학술대회논문집
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    • 한국소성가공학회 2003년도 춘계학술대회논문집
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    • pp.139-142
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    • 2003
  • In this study, casting/forging process was used to produce an aluminum lower control arm for automobiles. Firstly, casting experiments were carried out to get an enhanced preform for forging the lower control arm. In the casting experiment, the effect of an additive, Sr, on the mechanical properties such as tensile strength and elongation and the microstructure of a cast preform were investigated. And a finite element analysis was peformed to determine an optimal configuration of the cast preform. Lastly, a forging experiment was carried out to make the final product of aluminum lower control arm by using the above cast preform. In the casting experiments, when 0.025% Sr was added into molten A356, the maximum values of tensile strength and elongation of the cast preform were obtained. In the forging experiment, It was confirmed that the optimal configuration of a cast preform predicted by FE analysis was very useful. The cast/forged product using designed preform was made without any defects.

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