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Neutral zone approach for rehabilitation in a patient who underwent mandibulotomy: A case report (하악골 이단술을 시행한 환자에서 중립대를 활용한 상하악 총의치 수복 증례)

  • Heedo Shin;Hag-Young Lee;Jee-Hwan Kim
    • The Journal of Korean Academy of Prosthodontics
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    • v.61 no.1
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    • pp.18-25
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    • 2023
  • We present the case of a 65-year-old man with maxillary and mandibular complete dentures prepared using neutral zone technique after undergoing mandibulotomy due to tonsil cancer 10 years ago. The patient had a short edentulous period; hence, there was minimal absorption of the alveolar ridge and no abnormality in the motor function of the tongue. However, the retromolar pad was located inside the hamular notch, and the posterior alveolar ridge was relatively turned inward. If the artificial teeth would have been aligned conventionally, the functional space of the tongue would have been invaded, which would have moved the tongue posteriorly thereby reducing the stability of the denture. Therefore, applying the concept of the neutral zone can be a good reference point in such cases. The neutral zone was registered using tissue conditioner, and tooth alignment was performed by making a silicone putty index. The biggest advantage of using neutral zone concept is denture stability. In this case, the neutral zone technique was applied to obtain the lingual alignment limit of the posterior teeth to avoid invasion of the tongue space by the left posterior part of the mandible. Particularly, in case of a patient in which denture stability is difficult to obtain due to absorption of the alveolar ridge, it is believed that better results can be obtained using neutral zone technique.

A Study on the Altmetrics of the Papers of Library and Information Science Researchers Published in International Journals (국제 학술지에 발표된 문헌정보학 연구자 논문의 알트메트릭스에 관한 연구)

  • Jane Cho
    • Journal of Korean Library and Information Science Society
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    • v.53 no.4
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    • pp.143-162
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    • 2022
  • Altmetrics is an alternative impact evaluation index that evaluates the social interest in the research performance of individuals or institutions in universities, research institutions, and research fund support institutions. This study empirically analyzed what kind of attention a papers of domestic library and information science researchers published in an international academic journal was receiving in the international community using Altmetric explorer. As a result of the analysis, 230 papers were tracked. The average Altmetric Attention Score (AAS) was 6.63, but there were 2 papers that received overwhelming attention (over 170 points) as they were mentioned in news report and Twitter. Second, there was a tendency for high AAS to appear in cases where a domestic researcher participated as a co-author and the main author belonged to an overseas institution, and in the case where the research funds were supported by foreign government agencies. In addition to the field of the library information science or information system, the papers classified as the field of public health service and education showed high AAS, and it was confirmed that these papers were published in the journals of various fields such as life science. Finally, it was confirmed that there was a weak correlation of r =0.25 between the AAS and the number of citations of the analyzed paper, but a strong correlation of r =0.68 between the number of Mendeley readers and the number of citations.

A Study on the Correlation between Effective Impact Speed and the Severity of Collision Accidents with Fishing Vessels (유효충돌속도에 따른 어선 충돌사고 피해 상관성에 관한 연구)

  • Hyungoo Park;Young-Soo Park;Sang-Won Park
    • Journal of Navigation and Port Research
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    • v.47 no.4
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    • pp.202-211
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    • 2023
  • In maritime accidents, collisions involving fishing vessels are more frequent and severe than those involving other types of vessels. Previous cases of collision accidents caused by fishing vessels causing serious damage implied that fishing vessels maintained high speeds until just before the collision and that they collided with much larger vessels. This study investigated the correlation between the severity of ship damage resulting from fishing vessel collisions and the vessel's speed. The effective impact speed commonly used in the road transport sector was utilized to analyze ship collision accidents. The study collected collision data between fishing vessels and between fishing vessels and non-fishing vessels from accident investigation reports from 2016 to 2022. The effective impact speed was calculated for a total of 617 vessels. After using binary and multinomial logistic regression methodology, the analysis was carried out with effective impact speed as the independent variable and severity of accident as the dependent variable. The analysis revealed a statistically significant correlation between the effective impact speed and the severity of ship damage, indicating that the severity of ship damage is influenced not only by the effective impact speed but also by the tonnage of the vessel.

Mutations in GJB2 as Major Causes of Autosomal Recessive Non-Syndromic Hearing Loss: First Report of c.299-300delAT Mutation in Kurdish Population of Iran

  • Azadegan-Dehkordi, Fatemeh;Bahrami, Tayyebe;Shirzad, Maryam;Karbasi, Gelareh;Yazdanpanahi, Nasrin;Farrokhi, Effat;Koohiyan, Mahbobeh;Tabatabaiefar, Mohammad Amin;Hashemzadeh-Chaleshtori, Morteza
    • Journal of Audiology & Otology
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    • v.23 no.1
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    • pp.20-26
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    • 2019
  • Background and Objectives: Autosomal recessive non-syndromic hearing loss (ARNSHL) with genetic origin is common (1/2000 births). ARNSHL can be associated with mutations in gap junction protein beta 2 (GJB2). To this end, this cohort investigation aimed to find the contribution of GJB2 gene mutations with the genotype-phenotype correlations in 45 ARNSHL cases in the Kurdish population. Subjects and Methods: Genomic DNA was extracted from a total of 45 ARNSHL families. The linkage analysis with 3 short tandem repeat markers linked to GJB2 was performed on 45 ARNSHL families. Only 9 of these families were linked to the DFNB1 locus. All the 45 families who took part were sequenced for confirmation linkage analysis (to perform a large project). Results: A total of three different mutations were determined. Two of which [c.35delG and c.-23+1G>A (IVS1+1G>A)] were previously reported but (c.299-300delAT) mutation was novel in the Kurdish population. The homozygous pathogenic mutations of GJB2 gene was observed in nine out of the 45 families (20%), also heterozygous genotype (c.35delG/N)+(c.-23+1G>A/c.-23+1G>A) were observed in 4/45 families (8.8%). The degree of hearing loss (HL) in patients with other mutations was less severe than patients with c.35delG homozygous mutation (p<0.001). Conclusions: Our data suggest that GJB2 mutations constitute 20% of the etiology of ARNSHL in Iran; moreover, the c.35delG mutation is the most common HL cause in the Kurdish population. Therefore, these mutations should be included in the molecular testing of HL in this population.

Mortality rate undergoing anesthesia in Thoroughbred racehorses at Busan Race Park (부산경남경마공원 Thoroughbred 경주마의 마취중 치사율)

  • Yang, Jaehyuk;Park, Yong-Soo
    • Journal of Practical Agriculture & Fisheries Research
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    • v.17 no.1
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    • pp.125-132
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    • 2015
  • The report about equine anesthesias in Korea are very rare. This paper aimed at the mortality rate during anesthesia in Thoroughbred horses at Equine Hospital of Busan Race Park, KRA in South Korea from 2005 to 2010. Drugs used in anesthesia was IV injection of detomidine hydrochloride (0.01 mg/kg) or xylazine(0.5mg/kg) for sedation and premedication, Guaifenesin(50-100 mg/kg) for muscle relaxation, ketamine hydrochloride(2 mg/kg) for induction of anaesthesia and Inhalational isoflurane(1.3-1.5 %) to maintain anesthesia. Total number of anesthetic cases was 190, 150 of inhalational anesthesia and 40 of general anesthesia, repectively. The purpose of anesthesia was highest in the disorder of musculoskeletal system, followed by urogenital system and respiratory system Mortality case due to anesthesia was one during arthroscopic surgery for removal of osteochondral chip fragments. The time of anesthesia was 150 min, fatal sign was hypoxemia and the reason was improper machine operation of the anesthetist. In conclusion, the perianesthetic mortality rate during anesthesia in Thoroughbred horses at Busan Race Park was 0.52%(1 death per 190 anesthetics).

Clinical Outcomes and Contributors in Contemporary Kidney Transplantation: Single Center Experience (근래의 신장이식 임상성적과 관련인자들: 단일기관 연구)

  • Ahn, Jae-Sung;Park, Kyung Sun;Park, Jongha;Chung, Hyun Chul;Park, Hojong;Park, Sang Jun;Cho, Hong Rae;Lee, Jong Soo
    • Korean Journal of Transplantation
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    • v.31 no.4
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    • pp.182-192
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    • 2017
  • Background: In recent years, introduction of novel immunosuppressive agents and its proper implementation for clinical practice have contributed to improving clinical outcomes of kidney transplantation (KT). Here, we report clinical outcomes of KTs and related risk factors. Methods: From July 1998 to June 2016, 354 KTs (182 from living and 172 from deceased donors) have been performed at Ulsan University Hospital. We retrospectively reviewed the clinical characteristics and outcomes of KT recipients, then estimated graft and patient survival rate were estimated and analyzed risk factors using Cox-regression. Results: The median follow-up period was 53 months (range; 3 to 220 months). The mean ages of recipients and donors were 45.0 years (SD, 12.5) and 44.7 years (SD, 13.6) years, respectively. During follow-up, 18 grafts were lost and 5- and 10-year death-censored graft survival was 96.7% and 91.5%, respectively. Biopsy-proven acute rejection (BPAR) occurred in 71 patients (55 cases of acute cellular rejection and 16 of antibody-mediated rejection). Cox-regression analysis showed that BPAR was a risk factor related to graft loss (hazard ratio [HR], 14.38; 95% confidence interval [CI], 3.79 to 54.53; P<0.001). In addition, 15 patients died, and the 5- and 10-year patient survival was 97.2% and 91.9%, respectively. Age ≥60 years (HR, 6.03; 95% CI, 1.12 to 32.61; P=0.037) and diabetes (HR, 6.18; 95% CI, 1.35 to 28.22; P=0.019) were significantly related to patient survival. Conclusions: We experienced excellent clinical outcomes of KT in terms of graft failure and patient survival despite the relatively high proportion of deceased donors. Long-term and short-term clinical outcomes have improved in the last two decades.

Mutations in GJB2 as Major Causes of Autosomal Recessive Non-Syndromic Hearing Loss: First Report of c.299-300delAT Mutation in Kurdish Population of Iran

  • Azadegan-Dehkordi, Fatemeh;Bahrami, Tayyebe;Shirzad, Maryam;Karbasi, Gelareh;Yazdanpanahi, Nasrin;Farrokhi, Effat;Koohiyan, Mahbobeh;Tabatabaiefar, Mohammad Amin;Hashemzadeh-Chaleshtori, Morteza
    • Korean Journal of Audiology
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    • v.23 no.1
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    • pp.20-26
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    • 2019
  • Background and Objectives: Autosomal recessive non-syndromic hearing loss (ARNSHL) with genetic origin is common (1/2000 births). ARNSHL can be associated with mutations in gap junction protein beta 2 (GJB2). To this end, this cohort investigation aimed to find the contribution of GJB2 gene mutations with the genotype-phenotype correlations in 45 ARNSHL cases in the Kurdish population. Subjects and Methods: Genomic DNA was extracted from a total of 45 ARNSHL families. The linkage analysis with 3 short tandem repeat markers linked to GJB2 was performed on 45 ARNSHL families. Only 9 of these families were linked to the DFNB1 locus. All the 45 families who took part were sequenced for confirmation linkage analysis (to perform a large project). Results: A total of three different mutations were determined. Two of which [c.35delG and c.-23+1G>A (IVS1+1G>A)] were previously reported but (c.299-300delAT) mutation was novel in the Kurdish population. The homozygous pathogenic mutations of GJB2 gene was observed in nine out of the 45 families (20%), also heterozygous genotype (c.35delG/N)+(c.-23+1G>A/c.-23+1G>A) were observed in 4/45 families (8.8%). The degree of hearing loss (HL) in patients with other mutations was less severe than patients with c.35delG homozygous mutation (p<0.001). Conclusions: Our data suggest that GJB2 mutations constitute 20% of the etiology of ARNSHL in Iran; moreover, the c.35delG mutation is the most common HL cause in the Kurdish population. Therefore, these mutations should be included in the molecular testing of HL in this population.

Spontaneous Resolution of Iatrogenic Calcinosis Cutis after Parenteral Calcium Gluconate Therapy in Neonates (신생아에서 비경구적 칼슘 글루코네이트 요법 이후의 의인성 피부 석회침착증 후 자연관해)

  • Song, Kwang Soon;Lee, Si Wook;Kim, Du-Han;Min, Kyung-Keun;Yon, Chang Jin
    • Journal of the Korean Orthopaedic Association
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    • v.54 no.2
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    • pp.192-196
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    • 2019
  • Iatrogenic calcinosis cutis is due to the intravenous administration of calcium gluconate or calcium chloride to treat hypocalcemia. The arthors report three cases of calcinosis cutis with calcifications involving the upper or lower extremities in neonates following the extravasation of calcium gluconate. Three neonates, a 2-week-old girl, 4-week-old boy, and a 4-week-old girl, were consulted for indurated nodules after the intravenous administration of calcium gluconate at the intensive care unit. Complete remission of palpable nodule and calcification was observed on the radiograph at three weeks, four weeks and six months after the initial presentation in each. All three neonates with iatrogenic calcinosis curtis were resolved spontaneously without functional and cosmetic complications. According to enhancement of the patient's cognition about benign disease, a suitable explanation of the disease and avoiding unnecessary treatment through an early diagnosis of iatrogenic calcinosis cutis will reduce a number of potential medical malpractice disputes.

Improvement of Encoding Detection Algorithm for Multi-byte Encoded Data with Errors (오류가 발생한 멀티바이트 인코딩 데이터의 인코딩 기법 판별 알고리즘 개선)

  • Bae, Junwoo;Kim, Seonbeom;Park, Heejin
    • The Journal of Korean Institute of Next Generation Computing
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    • v.13 no.2
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    • pp.18-25
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    • 2017
  • In computer science, an encoding is a standardization of converting information to one format for audio, video or text. Therefore, the encoding information of the data should be known to open and read it and there are algorithms detecting encoder of the data. However, some informations of data could be disappeared by packet loss when transmitted on network, especially, if the data is snatched by packet sniffing or eavesdropping from wireless communications. In this paper, we improve the performance of encoding detection algorithm of 'uchardet' program for multi-byte encoded data with errors based on bit-shift algorithm. To simulate the performance, we generated Korean and Japanese text data with errors that is removed some random bits at random positions. Then the detection algorithm are tested using the data and 'uchardet-bitshift' showed better performance than 'uchardet'. When Korean texts are used, 'uchardet' could detect perfectly with ≤0.005% errors but it showed 0% detection rate with ≥1% errors while 'uchardet-bitshift' detected perfectly with ≤0.05% errors and it showed correct detection cases with ≥1% errors. Japanese texts with errors tend to report falsely as Chinese encoding because Japanese texts include lots of Chinese characters. As a results, we improved encoding detection algorithms by applying bit shift operation.

Conversion to Veno-arteriovenous Extracorporeal Membrane Oxygenation for Differential Hypoxia

  • Ho Jeong Cha;Jong Woo Kim;Dong Hoon Kang;Seong Ho Moon;Sung Hwan Kim;Jae Jun Jung;Jun Ho Yang;Joung Hun Byun
    • Journal of Chest Surgery
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    • v.56 no.4
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    • pp.274-281
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    • 2023
  • Background: Patients who require initial venoarterial extracorporeal membrane oxygenation (VA ECMO) support may need to undergo veno-arteriovenous ECMO (VAV ECMO) conversion. However, there are no definitive criteria for conversion to VAV ECMO. We report 9 cases of VAV ECMO at Gyeongsang National University Changwon Hospital, Gyeongsang National University College of Medicine. Methods: Of 158 patients who received ECMO support between January 2017 and June 2019, 82 were supported by initial VA ECMO. We retrospectively reviewed the medical records of 9 patients (7 men and 2 women; age, 53.1±19.4 years) who had differential hypoxia and required VAV ECMO support. Percutaneous transaortic catheter venting was used to detect the differential hypoxia. Results: Among the 82 patients who received VA ECMO support, 9 (10.9%) had differential hypoxia and required conversion to VAV ECMO support. The mean time from VA ECMO support to VAV ECMO support and the mean duration of the VAV support were 2.1±2.2 days and 1.9±1.5 days, respectively. The average peak inspiratory pressure before and after VAV ECMO application was 23.89±3.95 cmH2O and 20.67±5.72 cmH2O, respectively, decreasing by an average of 3.2±3.5 cmH2O (p=0.040). The PaO2/FiO2 ratio was kept below 100 mm Hg in survivors and non-survivors for 116±65.4 and 250±124.9 minutes, respectively (p=0.016). Six patients underwent extracorporeal cardiopulmonary resuscitation, of whom 4 survived (67%). The overall survival rate of patients who underwent conversion from VA ECMO to VAV ECMO was approximately 56%. Conclusion: Rapid detection of differential hypoxia is required when VA ECMO is applied, and efficient conversion to VAV ECMO may be critical for patient survival.