• 한국생물공학회:학술대회논문집
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• 2005.10a
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• pp.868-869
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• 2005

• Journal of Korean society of Dental Hygiene
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• v.18 no.5
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• pp.653-664
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• 2018

Objectives: The purpose of this study was to examine the association between two major oral diseases and cardiovascular diseases. Methods: Data from the 6th Korean National Health and Nutrition Examination Survey (2013-2015) were used. The study included 12,754 adults, aged ${\geq}19years$, who participated in the questionnaire survey of health related to hypertension, stroke, myocardial infarction, and angina pectoris as well as completed blood tests, anthropometry, and oral examination. Statistical analyses included complex sample frequency, complex sample general linear, complex sample cross-tabulation, and complex sample logistic regression analyses. Results: With respect to the number of Decayed-Missing-Filled-Teeth(DMFT ), patients with hypertension (DMFT 8.05), stroke (DMFT 8.66), and angina pectoris (DMFT 8.24) showed a DMFT score of >2, compared with those who did not have these diseases (p<0.05). Patients with hypertension, stroke, myocardial infarction, and angina pectoris presented an approximately 2.7, 3.5, 4, and 3 times higher incidence of periodontal diseases, respectively, than those who did not (p<0.05). Based on the analysis of the relationship between the number of DMFT and cardiovascular diseases, patients with cardiovascular diseases had a risk of 1.033 higher DMFT than those who did not (p<0.05). As per the analysis of the relationship between periodontal diseases and cardiovascular diseases, patients with cardiovascular diseases had a 2.969 higher risk of periodontaldiseasesthanthosewithout them (p<0.05). Conclusions: Two major oral diseases were found to be associated with cardiovascular diseases. Therefore, to prevent these major oral diseases in patients with cardiovascular diseases, oral hygiene management must be actively performed.

• The Journal of Internal Korean Medicine
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• v.28 no.4
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• pp.717-726
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• 2007

Objectives : This study was conducted to assess the effect of Uhwangchungsimwon on the autonomic nervous system. Methods : Eligible subjects were enrolled from healthy people in their 20s-30s. They were divided into two groups, the UC group (n=22) and the control group (n=20). We monitored ECG from 14:00 to 18:00 in both groups. In the UC group, subjects were administered UC at 15:00. HRV analysis was conducted at 14:00, 16:00, and 17:00 for 512 seconds. Results : The degree of LF/HF ratio change was significantly higher in the UC group at 1 hour after administration. Conclusion : We suggest Uhwangchungsimwon may be useful for stabilization of the autonomic nervous system by activating parasympathetic nerve in healthy people.

• The Journal of Korean Oriental Chronic Disease
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• v.10 no.1
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• pp.46-52
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• 2005

When we prescribed Shiryungtang to a 65 years-old male patient with ARF after stroke, we could observe that his symptoms, I/O balance and laboratory findings were all improved. Therefore, we suggest that shiryungtang might be useful for ARF in the patient with stroke.

• The Journal of Internal Korean Medicine
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• v.27 no.1
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• pp.197-207
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• 2006

The object of this study was to examine the relationship between arteriosclerosis and oriental medical diagnosis of the patients who had suffered ischemic stroke. The degree of arteriosclerosis of the patients was assessed by cardio-ankle vascular index(CAVI), and diagnostic criteria used for all patients were deficiency of ki, deficiency of blood, blood stasis and stagnation of water. One hundred four patients were included and their general characteristics, CAVI and oriental diagnosis were evaluated. Results showed a significantly strong correlation between CAVI and blood stasis. These results suggest a close relationship between arterioslcerosis and blood static syndrome as defined by oriental medicine. If so, diagnosis of blood static syndrome is a reilable predictor of arteriosclerosis.

• The Journal of Korean Medicine
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• v.30 no.1
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• pp.95-108
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• 2009

Objectives: Uwhangchungsim-won (DC) has been used in various medical fields such as stroke, hypertension, atherosclerosis, autonomic imbalance and mental instability, etc. The aim of this study was to evaluate the effect of UC on cerebral hemodynamics and estimate the appropriate dose of UC. Methods: We studied changes of hyperventilation-induced cerebrovascular reactivity and mean blood flow velocity of middle cerebral arteries (MCA) using transcranial Doppler. We observed the changes of mean blood pressure, pulse rate and expiratory CO2 using S/5 Compact Anesthesia Monitor from 10 healthy young volunteers who were administered UC twice a day in the 1 st section and then once a day in the 2nd section. Results: Mean blood pressure tended to decrease at 1 hour and pulse rate tended to decrease at 2 hours after second administration. After 2 hours, mean blood pressure rose to state before administration, but pulse rate maintained from 2 hours to 4 hours. The changes were not statistically significant. Cerebral blood flow velocity in middle cerebral artery was not statistically significant after second administration. Cerebrovascular reactivity increased from 2 hours to 4 hours after second administration. Conclusions: This study provides that administration of UC twice a day is more effective on hyperventilation-induced cerebrovascular reactivity than administration of UC once a day.

• The Journal of Internal Korean Medicine
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• v.28 no.3
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• pp.421-433
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• 2007

Objectives : This study was performed to evaluate the relationships among blood-stasis. cardio-ankle vascular index(CAVI) and cardiovascular risk. Methods : We obtained general characteristics. blood-stasis score and CAVI from 150 stroke patients. Blood-stasis score was evaluated by blood-stasis criteria. Cardiovascular risk (the following. Stuart's risk score) was evaluated by Stuart's risk scoring scale. We divided subjects into a blood-stasis group and a non blood-stasis group by blood-stasis scores. high CAVI and normal CAVI groupsby CAVI. We compared the general characteristics. CAVI (excluded from comparison between high CAVI group and normal CAVI group), Stuart's risk score and blood-stasis score (excluded from comparison between blood-stasis group and non blood-stasis group) between each pair of groups. Pearson correlation analysis was applied to examine the relationship between blood stasis score and CAVI, blood stasis score and Stuart's risk score. CAVI and Stuart's risk score. Results : The blood-stasis group had significantly higher CAVI and Stuart's risk scores than the non blood stasis group. The high CAVI group had significantly higher blood-stasis score and Stuart's risk score than the normalCAVI group. In correlation analysis. there were significant positive relationship between blood stasis score and Stuart's risk score, CAVI and Stuart's risk score. and blood stasis score and CAVI. Conclusions : This study suggeststhat there is a significant relationship among blood stasis,CAVI and cardiovascular risk.

• Korean Circulation Journal
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• v.48 no.12
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• pp.1160-1162
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• 2018

• Advances in Traditional Medicine
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• v.7 no.5
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• pp.579-582
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• 2008

This study was aimed to evaluate the effectiveness of moxibustion on dysphagia after stroke. We conducted his study in the Department of Cardiovascular and Neurologic Diseases (Stroke Center), Hospital of Oriental Medicine, Kyung Hee Medical Center, from May 1, 2005 to August 1, 2006. After recruiting dysphagia patients after stroke, we applied the Direct Moxibustion ($1.2\;{\times}\;1.4\;cm$) to the Chon-Jung acupoint 5 times, and assessed its effect on swallowing reflex by Swallowing Provocation Test (SPT) before and 30 min after treatment. Effectiveness of the swallowing reflex was assessed by the Latency Time of Swallowing Reflex (LTSR) which was checked from test starting to the onset of swallowing reflex. Thirty four subjects with dysphagia were treated with moxibustion. The mean of the latency time in swallowing reflex was shortened from $2.2\;{\pm}\;0.9$ to $1.5\;{\pm}\;0.5$ seconds after moxibustion, which had statistical significance (P < 0.001). We suggest that moxibustion at Chon-Jung could be useful for dysphagia after stroke. Further study with a randomized controlled trial compared to placebo is needed to confirm this suggestion.

• The Journal of Korean Medicine
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• v.28 no.4
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• pp.69-73
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• 2007

Objectives : With an assumption of the traditional oriental medical theory, we were to evaluate the effect of tonification/sedation-manipulated acupuncture on autonomic nervous activity in healthy subjects. Methods : This study is a randomized cross-over trial. We enrolled healthy subjects, and assigned them randomly into group A or group B. Group A received acupuncture therapy on Shen-Men (He-7) and Nei-Kuan (EH-6) with tonification-manipulation, while Group B received it with sedation-manipulation. Their heart rate variability was monitored for 2 hours. After 3 days of washout period, the subjects were crossed over to the other manipulation method, and the same procedures were performed. Results : There was no statistical significance in the change of RR, SDNN, LF, HF, and LF/HF ratio between the tonification-manipulated and the sedation-manipulated groups. However, HF curve in the tonification manipulated group showed increasing tendency for 15 minutes after acupuncture. Conclusions :We suggest that the traditional tonification-manipulated acupuncture on Shen-Men and Nei-Kuan could increase parasympathetic activity shortly after acupuncture, but further evaluation on a larger sample size is needed to confirm this suggestion.