• 제목/요약/키워드: carbon-ion irradiation

검색결과 45건 처리시간 0.027초

Telomere-Mitochondrion Links Contribute to Induction of Senescence in MCF-7 Cells after Carbon-Ion Irradiation

  • Miao, Guo-Ying;Zhou, Xin;Zhang, Xin;Xie, Yi;Sun, Chao;Liu, Yang;Gan, Lu;Zhang, Hong
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권4호
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    • pp.1993-1998
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    • 2016
  • The effects of carbon-ion irradiation on cancer cell telomere function have not been comprehensively studied. In our previous report cancer cells with telomere dysfunction were more sensitive to carbon-ion irradiation, but the underlying mechanisms remained unclear. Here we found that telomerase activity was suppressed by carbon-ion irradiation via hTERT down-regulation. Inhibition of telomere activity by MST-312 further increased cancer cell radiosensitivity to carbon-ion radiation. hTERT suppression caused by either carbon-ion irradiation or MST-312 impaired mitochondrial function, as indicated by decreased membrane potential, mtDNA copy number, mitochondrial mass, total ATP levels and elevated reactive oxygen species (ROS). PGC-$1{\alpha}$ expression was repressed after carbion-ion irradiation, and hTERT inhibition by MST-312 could further exacerbate this effect. Lowering the mitochondrial ROS level by MitoTEMPO could partially counteract the induction of cellular senescence induced by carbon-ion radiation and MST-312 incubation. Taken together, the current data suggest that telomere-mitochondrion links play a role in the induction of senescence in MCF-7 cells after carbon-ion irradiation.

탄소섬유복합재의 표면개질에 따른 트라이볼로지 특성에 관한 연구 (Tribological Characteristics of Carbon Fiber Reinforced Plastics by Surface modification)

  • 전승흥;양준호;오성모;이봉구
    • 한국윤활학회:학술대회논문집
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    • 한국윤활학회 2000년도 제32회 추계학술대회 정기총회
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    • pp.29-36
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    • 2000
  • This investigation has been studied about friction and wear properties which were important problem, when carbon fiber reinforced plastic(CFRP) was used practically. Unidirection carbon fiber reinforced composites was fabricated with epoxy resin matrix and carbon fiber as a reinforced, and its surface was modified by the ion-assisted reaction. And then we tested the their friction and wear properties according to the ion-irradiation. when the amount of ion-irradiation was 1${\times}$10l6$\^$16/ ions/$\textrm{cm}^2$, the friction coefficient values were about 0.1, where as, the friction coefficient values of non-treatment composites were about 0.16. The former was the stablest in wear mode. We know that ion-irradiation was not proportioned to the friction coefficient, so we found the optimal conditions of the friction and wear according to the ion-irradiation.

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이온도움반응법에 의한 탄소섬유복합재의 트라이볼로지 특성연구 (Tribological Characteristics of Carbon Fiber Reinforced Plastics Prepared by Ion-Assisted Reaction)

  • 오성모;김정기;이봉구
    • 한국정밀공학회지
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    • 제21권4호
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    • pp.103-108
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    • 2004
  • Carbon fiber reinforced composites(CFRP) were fabricated with phenolic resin matrix by hot press molding, and its surface was modified by the ion-assisted reaction process. When we tested the friction coefficient and wear rate variation and observed the effect of fibers with respect to friction and wear characteristics, the amount of pitch based carbon fiber was 45wt% and the average friction coefficient was the lowest at 0.12. When the amount of ion-irradiation was $1\times10^{l6}ions/cm^2$, the friction coefficient of the composites was about 0.12 and the wear mode was stable, whereas, the friction coefficient of the non-treated composites was about 0.16 and the wear mode was very unstable. But if the amount of ion-irradiation was $5\times10^{l6}ions/cm^2$$1\times10^{l6}ions/cm^2$ion-irradiation case.

표면개질에 따른 탄소섬유복합재의 마찰마모 특성에 관한 연구 (A Study on the Friction and Wear Characteristics of Carbon Fiber Reinforced Plastics by Surface Modification)

  • 오성모;이봉구
    • 한국정밀공학회지
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    • 제18권8호
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    • pp.122-128
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    • 2001
  • The objective of the present study was to investigate the characteristics of the friction and wear according to the amount of ion-irradiation for the carbon fiber reinforced plastic(CFRP). Unidirectional carbon fiber reinforced composites were fabricated with epoxy resin as a matrix and carbon fiber as a reinforcement, and its surface was modified by the ion-assisted reaction. When the amount of ion-irradiation was $1{\times}10^{16}$ ions/$cm^2$, the friction coefficients of composites were about 0.1 and the wear mode was stable, whereas, the friction coefficient of non-treatment composites were about 0.16 and the wear mode was very unstable. But if the amount of ion-irradiation was $5{\times}10^{16}$ ions/$cm^2$, the friction coefficients were higher rather than that of $1{\times}10^{16}$ ions/$cm^2$. Consequently, the amount of ion-irradiation was not in proportion to the friction coefficients, and it was conformed that the optimal conditions would exist between broth of them.

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탄소섬유복합재의 표면개질에 따른 트라이볼로지 특성에 관한 연구 (Tribological Characteristics of Surface Modification by Carbon Fiber Reinforced Plastics)

  • 김종희;전승홍;이봉구;오성모
    • Tribology and Lubricants
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    • 제18권1호
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    • pp.61-67
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    • 2002
  • The objective of the present study was to investigate the characteristics of the friction and wear according to the amount of ion-irradiation for the carbon fiber reinforced plastic (CFRP). Unidirectional carbon fiber reinforced composites were fabricated with epoxy resin as a matrix and carbon fiber as a reinforcement, and its surface was modified by the ion-assisted reaction. When the amount of ion-irradiation was $1{\times}10^{16}$ $ions/cm^{2}$. the friction coefficients of composites were about 0.1 and the wear mode was stable. whereas, the friction coefficient of non-treatment composites were about 0.16 and the wear mode was very unstable. But if the amount of ion-irradiation was $5{\times}10^{16}$ $ions/cm^{2}$, the friction coefficients were higher rather than that of $1{\times}10^{16}$ $ions/cm^{2}$ Consequently. the amount of ion-irradiation was not in proportion to the friction coefficients, and it was conformed that the optimal conditions would exist between both of them.

a-C:H 박막의 물성 변화에 따른 액정 배향 특성에 관한 연구 (A study on liquid crystal alignment characteristics by the properties of hydrogenated amorphous carbon thin films)

  • 이대규;노순준;백홍구;황정연;조용민;서대식
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2002년도 하계학술대회 논문집 Vol.3 No.2
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    • pp.839-844
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    • 2002
  • This letter focuses on the liquid crystal alignment characteristics according to the properties of hydrogenated amorphous carbon(a-C:H) thin film deposited by RPECVD(Remote Plasma Enhanced Chemical Vapor Deposition) method using $C_2H_2$ and He gases. The properties of the deposited thin films were controlled by the ion beam irradiation time and ion beam energy. The results show that not ion beam energy but ion beam irradiation time plays an important role in the properties of a-G:H thin films. As the ion beam irradiation time increases, not only the sp2 concentration in a-G:H thin films but also liquid crystal pretilt angle was varied.

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Enhanced Field Emission and Luminescent Properties of Straightened Carbon Nanotubes to be Applied in Field Emission Display

  • Lee, Hyeong-Rag;Kim, Do-Hyung;Kim, Chang-Duk;Jang, Hoon-Sik
    • Journal of Information Display
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    • 제4권2호
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    • pp.35-42
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    • 2003
  • The field emission and luminescent properties of carbon nanotubes (CNTs) that were straightened by argon ion irradiation were investigated. Argon ion irradiation permanently straightened both as-grown and screen-printed CNTs (SP-CNTs) in the presence of a strong electric field. The straightening process enhanced the emission properties of as-grown CNT films by showing a decrease in turn-on field, an increase in total emission current, and a stable emission. Recurring problems associated with SP-CNTs, such as bent or/and buried CNTs and the degradation in binder-residue-induced emission, were improved by the permanent straightening of CNTs and protruding CNTs from binders by the irradiation treatment, in addition to its surface cleaning effect. Furthermore, we confirmed that the number of emission sites increases by observing the luminescent properties of CNT films after the straightening. These findings here suggest that ion irradiation treatment is an effective method for achieving uniform field emission and to reduce the electrical aging time.

Multidirectional Liquid Crystal Orientation by Using Ion Beam Irradiation

  • Ahn, Han-Jin;Kim, Kyung-Chan;Kim, Jong-Bok;Hwang, Byung-Har;Baik, Hong-Koo
    • 한국정보디스플레이학회:학술대회논문집
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    • 한국정보디스플레이학회 2005년도 International Meeting on Information Displayvol.I
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    • pp.543-546
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    • 2005
  • We have investigated the alignment ability of multi-domains by using ion beam irradiation on diamond-like carbon (DLC) thin film layers. The DLC thin films were deposited by plasma enhanced chemical vapor deposition (PECVD) system and the low energy ion beam is irradiated from Kaufman type ion gun. The direction of liquid crystal alignment is varied by the direction of Ar ion beam irradiation.

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Preparation of photoresist-derived carbon micropatterns by proton ion beam lithography and pyrolysis

  • Nam, Hui-Gyun;Jung, Jin-Mook;Hwang, In-Tae;Shin, Junhwa;Jung, Chang-Hee;Choi, Jae-Hak
    • Carbon letters
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    • 제24권
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    • pp.55-61
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    • 2017
  • Carbon micropatterns (CMs) were fabricated from a negative-type SU-8 photoresist by proton ion beam lithography and pyrolysis. Well-defined negative-type SU-8 micropatterns were formed by proton ion beam lithography at the optimized fluence of $1{\times}10^{15}ions\;cm^{-2}$ and then pyrolyzed to form CMs. The crosslinked network structures formed by proton irradiation were converted to pseudo-graphitic structures by pyrolysis. The fabricated CMs showed a good electrical conductivity of $1.58{\times}10^2S\;cm^{-1}$ and a very low surface roughness.

Ar+ 이온 빔 조사가 탄소섬유와 열경화성 수지 간 계면결합력에 미치는 영향 (Effects of Ar+ ion Beam Irradiation on the Adhesion Forces between Carbon fibers and Thermosetting Resins)

  • 박수진;서민강;김학용;이경엽
    • 폴리머
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    • 제26권6호
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    • pp.718-727
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    • 2002
  • 본 연구에서는 최종 복합재료의 기계적 계면특성을 향상시키기 위하여 산소 분위기 하에서 반응성 기체를 사용하는 이온 보조 반응법에 의해 탄소섬유 표면에 Ar+ 이온 빔을 조사하였다. 그리고, 단일 섬유 pull-out 시험을 실시하여 가해진 이온 에너지 세기에 대한 수지 내의 섬유의 뽑힘 정도를 측정한 후 Greszczuk의 .기하학적 모델에 기초하여 섬유/매트릭스 간의 계면특성을 알아보고자 하였다. 그 결과, 탄소섬유를 이온 빔으로 처리함에 따라 섬유와 매트릭스 간의 부착력 증가의 원인이 되는 섬유축 방향으로의 표면 etching 및 반응성 그룹이 형성되어 계면 전단강도가 향상되었으며 0.8 keV 이온 빔 세기에서 최대값을 나타내었다.