• 한국사회정책
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• 제20권3호
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• pp.9-46
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• 2013

사회보장법에 나타나는 위임의 정도는 의회의원후보공천방식과 의회상임위원회제도의 운영방식과 관련이 있다. 위임이 적은 사회보장법 구조는 상향식 공천방식과 지속적으로 임기를 보장하는 상임위원회제도와 친화적이다. 독일과 같이 당원이 연방의원후보를 결정하는 과정에서 중요한 역할을 하는 상향식 공천방식과 지속적인 임기를 보장하는 상임위원회제도는 위임이 적은 독일의 사회법과 친화성을 갖는다. 반면에 위임이 많은 사회보장법 구조는 하향식 공천방식과 지속적인 임기를 보장하지 않는 상임위원회제도와 친화적이다. 우리나라와 같이 국회의원후보자를 중앙당에서 주도적으로 결정하는 하향식 공천방식과 지속적인 임기를 보장하지 않는 상임위원회제도는 위임이 많은 우리나라의 사회보장법과 친화성을 갖는다.

• Journal of Dairy Science and Biotechnology
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• 제18권1호
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• pp.47-60
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• 2000

Over decades of work, the probiotic research has grown rapidly with a number of new cultures, which is claimed a variety of benefit. However, many of the specific effects attributed to the ingestion of probiotics remain convoluted and scientifically unsubstantiated. Accordingly, the scientific community faces a greater challenge and must objectively seek cause and effect relationships for many potential and currently investigated probiotic species. Rational selection and design of probiotics remains an important challenge and will require a solid information about the physiology and genetics of candidate strains relevant to their intestinal roles, functional activities, and interaction of with other resident micro flora. As far as beneficial culture of lactic acid bacteria (LAB) is concerned, simple, cost-effective, and exact identification of candidate strains is of foremost importance among others. Until recently, the relatedness of bacterial isolates has been determined sorely by testing for one or several phenotyphic markers, using methods such as serotyping, phage-typing, biotyping, and so forth. However, there are problems in the use of many of these phenotype-based methods. In contrast, some of newer molecular typing methods involving the analysis of DNA offer many advantages over traditional techniques. These DNA-based methods have the greater discriminatory power than that of phenotypic procedures. This review focuses on the importance and the basis of molecular typing methods along with some considerations on de-sign and selection of probiotic culture for human consumption.

• Communications for Statistical Applications and Methods
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• 제28권2호
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• pp.189-204
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• 2021

In a regression analysis, a single best model is usually selected among several candidate models. However, it is often useful to combine several candidate models to achieve better performance, especially, in the prediction viewpoint. Model combining methods such as stacking and Bayesian model averaging (BMA) have been suggested from the perspective of averaging candidate models. When the candidate models include a true model, it is expected that BMA generally gives better performance than stacking. On the other hand, when candidate models do not include the true model, it is known that stacking outperforms BMA. Since stacking and BMA approaches have different properties, it is difficult to determine which method is more appropriate under other situations. In particular, it is not easy to find research papers that compare stacking and BMA when regression model assumptions are violated. Therefore, in the paper, we compare the performance among model averaging methods as well as a single best model in the linear regression analysis when standard linear regression assumptions are violated. Simulations were conducted to compare model averaging methods with the linear regression when data include outliers and data do not include them. We also compared them when data include errors from a non-normal distribution. The model averaging methods were applied to the water pollution data, which have a strong multicollinearity among variables. Simulation studies showed that the stacking method tends to give better performance than BMA or standard linear regression analysis (including the stepwise selection method) in the sense of risks (see (3.1)) or prediction error (see (3.2)) when typical linear regression assumptions are violated.

• Communications for Statistical Applications and Methods
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• 제22권2호
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• pp.173-180
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• 2015

We propose a selection procedure of principal components in principal component regression. Our method selects principal components using variable selection procedures instead of a small subset of major principal components in principal component regression. Our procedure consists of two steps to improve estimation and prediction. First, we reduce the number of principal components using the conventional principal component regression to yield the set of candidate principal components and then select principal components among the candidate set using sparse regression techniques. The performance of our proposals is demonstrated numerically and compared with the typical dimension reduction approaches (including principal component regression and partial least square regression) using synthetic and real datasets.

• Genomics & Informatics
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• 제14권4호
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• pp.149-159
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• 2016

With the success of the genome-wide association studies (GWASs), many candidate loci for complex human diseases have been reported in the GWAS catalog. Recently, many disease prediction models based on penalized regression or statistical learning methods were proposed using candidate causal variants from significant single-nucleotide polymorphisms of GWASs. However, there have been only a few systematic studies comparing existing methods. In this study, we first constructed risk prediction models, such as stepwise linear regression (SLR), least absolute shrinkage and selection operator (LASSO), and Elastic-Net (EN), using a GWAS chip and GWAS catalog. We then compared the prediction accuracy by calculating the mean square error (MSE) value on data from the Korea Association Resource (KARE) with body mass index. Our results show that SLR provides a smaller MSE value than the other methods, while the numbers of selected variables in each model were similar.

• Communications for Statistical Applications and Methods
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• 제21권2호
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• pp.161-168
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• 2014

In mixture experiments with process variables, we consider the case that some of process variables are either uncontrollable or hard to control, which are called noise variables. Given the such mixture experimental data with process variables, first we study how to search for candidate models. Good candidate models are screened by the sequential variables selection method and checking the residual plots for the validity of the model assumption. Two methods, which use numerical optimization methods proposed by Derringer and Suich (1980) and minimization of the weighted expected loss, are proposed to find a cost-effective robust optimal condition in which the performance of the mean as well as the variance of the response for each of the candidate models is well-behaved under the cost restriction of the mixture. The proposed methods are illustrated with the well known fish patties texture example described by Cornell (2002).

• 한국정보과학회논문지:소프트웨어및응용
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• 제31권2호
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• pp.164-172
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• 2004

일반적으로 국지적 탐색에서 최적해를 획득할 가능성은 가능한 많은 이웃해를 생성하면서 반복 수를 늘릴수록 높아지나 긴 탐색시간이 소요된다. 따라서 한정된 시간 내에 최적해를 효율적으로 찾기 위해서는. 적절한 수의 이웃해를 생성하되, 탐색의 질을 높일 수 있는 이웃해를 선별해서 생성하는 것이 요구된다. 본 논문에서는 국지적 탐색기법을 적용하여 부하평준화 문제를 해결할 때, 탐색의 효율을 향상시킬 수 있는 이웃해 선정 기법을 제안하고, 실세계 데이타를 대상으로 그 성능을 검증하였다. 본 논문에서 제안하는 이웃해 선정 기법은 확률적 선별에 기반 한 방법으로서, 탐색의 질을 개선시킬 가능성에 대한 추정치를 기준으로 부여된 확률에 따라 이웃해를 선별하여 생성하는 기법이다. 대상 문제에 국지적 탐색기법으로 tabu 탐색과 simulated annealing를 적용한 실험에서, 무작위 또는 그리디 선별에 기반 한 방법보다 우수한 성능을 보임을 확인하였다.

• 한국산업보건학회지
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• 제24권4호
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• pp.587-612
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• 2014

Objectives: There is requirement to select candidate materials for chronic inhalation/carcinogenicity testing, so we would like to set the priority of candidate materials. Methods and Results: We recommend the priorities for candidate materials based on the chemicals stipulated in the Occupational Safety and Health Act(OSHAct) and the Toxic Chemicals Control Act(TCCA) in Korea. Conclusions: We presented candidate chemicals consisting of solids(powders), gases and liquids(Such as organic solvents) with priorities.

• 품질경영학회지
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• 제41권1호
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• pp.109-118
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• 2013

혼합물 성분비와 공정변수들에 관한 실험 자료가 주어진 경우에, 주어진 실험 자료를 잘 설명하는 적절한 결합모형을 찾는 것은 중요한 과제이다. 우선 모형 선택 기준에 부합하는 시작모형의 후보들을 교적모형의 범주에서 찾고, 다음으로 선택된 시작모형을 완전모형으로 간주하여, 모형의 간결성의 원칙에 따라서 완전모형의 부분모형으로 구성된 적절한 결합모형들을 찾는데, 일반적으로 여러 개의 결합모형들이 추천된다. 주어진 실험 자료에 대한 적절한 모형으로 여러 개의 모형이 추천된 경우에, 엔지니어들의 실용적인 관심사는 각각의 결합모형에 대한 반응변수의 기대값의 예측치와 예측치의 표준편차의 추정치를 동시에 최적으로 하는 최적조건의 찾기이다. 이를 위한 실용적인 방법으로 반응변수가 여러 개인 다중 반응표면 분석에서 동시 최적화 기법을 활용한 최적조건을 찾는 방법을 제안하고, 잘 알려진 혼합물성분-공정변수 실험 자료에 대해서 Design Expert 8.0을 활용하여 적절한 결합모형들을 찾고, 이 모형들을 동시에 최적화하는 최적조건 찾기가 예시된다.

• Asian-Australasian Journal of Animal Sciences
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• 제30권2호
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• pp.149-153
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• 2017

Objective: This study was to determine the relationship between estimated breeding value and phenotype information after farrowing when juvenile selection was made in candidate pigs without phenotype information. Methods: After collecting phenotypic and genomic information for the total number of piglets born by Landrace pigs, selection accuracy between genomic breeding value estimates using genomic information and breeding value estimates of best linear unbiased prediction (BLUP) using conventional pedigree information were compared. Results: Genetic standard deviation (${\sigma}_a$) for the total number of piglets born was 0.91. Since the total number of piglets born for candidate pigs was unknown, the accuracy of the breeding value estimated from pedigree information was 0.080. When genomic information was used, the accuracy of the breeding value was 0.216. Assuming that the replacement rate of sows per year is 100% and generation interval is 1 year, genetic gain per year is 0.346 head when genomic information is used. It is 0.128 when BLUP is used. Conclusion: Genetic gain estimated from single step best linear unbiased prediction (ssBLUP) method is by 2.7 times higher than that the one estimated from BLUP method, i.e., 270% more improvement in efficiency.