• 제목/요약/키워드: candidate materials

검색결과 809건 처리시간 0.026초

다중 양중장비와 자재 야적 위치의 최적 결정을 위한 모델 개발 (Optimization of Multiple Tower Cranes and Material Stockyards Layout)

  • 김경주;김경민;이상규
    • 한국건설관리학회논문집
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    • 제10권6호
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    • pp.127-134
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    • 2009
  • 본 연구에서는 여러 대의 타워 크레인이 다양한 후보지점을 갖고, 자재 역시 다양한 야적 후좌지점을 가질 때 자재 운반 최적화를 지원하기 위한 유전자 알고리즘 기반의 모델을 제시하고자 한다. 대형 건축공사에서 타워 크레인의 위치와 자재 야적 위치의 변화는 자재 운반시간의 변화를 가져온다. 또한 여러 대의 타워 크레인을 사용하는 경우 각 자재의 운반에 어떠한 타워 크레인을 배정하느냐에 따라 작업의 효율성이 변화한다. 따라서 본 연구에서는 다중의 타워 크레인 설치 후보지, 여러 종류의 자재, 자재 야적 후보지점간의 다양하고 복잡한 상관관계를 다루기 위하여 유전자 알고리즘을 적용한 다중 양중장비 및 자재 야적 위치 최적화모델을 제시하였다. 또한, 제시된 모델을 사례에 적용하여 적용 과정을 예시하고 활용성을 검증하였다.

PLK2 Single Nucleotide Variant in Gastric Cancer Patients Affects miR-23b-5p Binding

  • Dominkus, Pia Puzar;Mesic, Aner;Hudler, Petra
    • Journal of Gastric Cancer
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    • 제22권4호
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    • pp.348-368
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    • 2022
  • Purpose: Chromosomal instability is a hallmark of gastric cancer (GC). It can be driven by single nucleotide variants (SNVs) in cell cycle genes. We investigated the associations between SNVs in candidate genes, PLK2, PLK3, and ATM, and GC risk and clinicopathological features. Materials and Methods: The genotyping study included 542 patients with GC and healthy controls. Generalized linear models were used for the risk and clinicopathological association analyses. Survival analysis was performed using the Kaplan-Meier method. The binding of candidate miRs was analyzed using a luciferase reporter assay. Results: The PLK2 Crs15009-Crs963615 haplotype was under-represented in the GC group compared to that in the control group (Pcorr=0.050). Male patients with the PLK2 rs963615 CT genotype had a lower risk of GC, whereas female patients had a higher risk (P=0.023; P=0.026). The PLK2 rs963615 CT genotype was associated with the absence of vascular invasion (P=0.012). The PLK3 rs12404160 AA genotype was associated with a higher risk of GC in the male population (P=0.015). The ATM Trs228589-Ars189037-Grs4585 haplotype was associated with a higher risk of GC (P<0.001). The ATM rs228589, rs189037, and rs4585 genotypes TA+AA, AG+GG, and TG+GG were associated with the absence of perineural invasion (P=0.034). In vitro analysis showed that the cancer-associated miR-23b-5p mimic specifically bound to the PLK2 rs15009 G allele (P=0.0097). Moreover, low miR-23b expression predicted longer 10-year survival (P=0.0066) in patients with GC. Conclusions: PLK2, PLK3, and ATM SNVs could potentially be helpful for the prediction of GC risk and clinicopathological features. PLK2 rs15009 affects the binding of miR-23b-5p. MiR-23b-5p expression status could serve as a prognostic marker for survival in patients with GC.

Wavelength Conversion Lanthanide(III)-cored Complex for Highly Efficient Dye-sensitized Solar Cells

  • Oh, Jung-Hwan;Song, Hae-Min;Eom, Yu-Kyung;Ryu, Jung-Ho;Ju, Myung-Jong;Kim, Hwan-Kyu
    • Bulletin of the Korean Chemical Society
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    • 제32권8호
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    • pp.2743-2750
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    • 2011
  • Lanthanide(III)-cored complex as a wavelength conversion material has been successfully designed and synthesized for highly efficient dye-sensitized solar cells, for the first time, since light with a short wavelength has not been effectively used for generating electric power owing to the limited absorption of these DSSCs in the UV region. A black dye (BD) was chosen and used as a sensitizer, because BD has a relatively weak light absorption at shorter wavelengths. The overall conversion efficiency of the BD/WCM device was remarkably increased, even with the relatively small amount of WCM added to the device. The enhancement in $V_{oc}$ by WCM, like DCA, could be correlated with the suppression of electron recombination between the injected electrons and $I_3{^-}$ ions. Furthermore, the short-circuit current density was significantly increased by WCM with a strong UV light-harvesting effect. The energy transfer from the Eu(III)-cored complex to the $TiO_2$ film occurred via the dye, so the number of electrons injected into the $TiO_2$ surface increased, i.e., the short-circuit current density was increased. As a result, BD/WCM-sensitized solar cells exhibit superior device performance with the enhanced conversion efficiency by a factor of 1.22 under AM 1.5 sunlight: The photovoltaic performance of the BD/WCM-based DSSC exhibited remarkably high values, $J_{sc}$ of 17.72 mA/$cm^2$, $V_{oc}$ of 720 mV, and a conversion efficiency of 9.28% at 100 mW $cm^{-2}$, compared to a standard DSSC with $J_{sc}$ of 15.53 mA/$cm^2$, $V_{oc}$ of 689 mV, and a conversion efficiency of 7.58% at 100 mW $cm^{-2}$. Therefore, the Eu(III)-cored complex is a promising candidate as a new wavelength conversion coadsorbent for highly efficient dye-sensitized solar cells to improve UV light harvesting through energy transfer processes. The abstract should be a single paragraph which summaries the content of the article.

초고온가스로용 Alloy 617의 불순물 함유 헬륨/공기 중에서 고온부식 특성 (High Temperature Corrosion of Alloy 617 in Impure Helium and Air for Very High-Temperature Gas Reactor)

  • 정수진;이경근;김동진;김대종
    • Corrosion Science and Technology
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    • 제12권2호
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    • pp.102-112
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    • 2013
  • A very high-temperature gas reactor (VHTR) is one of the next generation nuclear reactors owing to its safety, high energy efficiency, and proliferation-resistance. Heat is transferred from the primary helium loop to the secondary helium loop through an intermediate heat exchanger (IHX). Under VHTR environment Alloy 617 is being considered a candidate Ni-based superalloy for the IHX of a VHTR, owing to its good creep resistance, phase stability and corrosion resistance at high temperature. In this study, high-temperature corrosion tests were carried out at 850 - $950^{\circ}C$ in air and impure helium environments. Alloy 617 specimens showed a parabolic oxidation behavior for all temperatures and environments. The activation energy for oxidation was 154 kJ/mol in helium environment, and 261 kJ/mol in an air environment. The scanning electron microscope (SEM) and energy-dispersive x-ray spectroscopy (EDS) results revealed that there were a Cr-rich surface oxide layer, Al-rich internal oxides and depletion of grain boundary carbide after corrosion test. The thickness and depths of degraded layers also showed a parabolic relationship with the time. A corrosion rate of $950^{\circ}C$ in impure helium was higher than that in an air environment, caused by difference in the outer oxide morphology.

자발적 상분리법과 수열합성법을 이용한 ZnO계 일차원 나노구조의 수직 합성법 연구

  • 조형균;김동찬;배영숙
    • 한국재료학회:학술대회논문집
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    • 한국재료학회 2009년도 추계학술발표대회
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    • pp.5.2-5.2
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    • 2009
  • From 10 years ago, the development of nano-devices endeavored to achieve reconstruction of information technology (IT) and nano technology (NT) industry. Among the many materials for the IT and NT industry, zinc oxide (ZnO) is a very promising candidate material for the research of nano-device development. Nano-structures of ZnO-based materials were grown easily via various methods and it attracts huge attention because of their superior electrical and optical properties for optoelectronic devices. Recently, among the various growth methods, MOCVD has attracted considerable attention because it is suitable process with benefits such as large area growth, vertical alignment, and accurate doping for nano-device fabrication. However, ZnO based nanowires grown by MOCVD process were had the principal problems of 1st interfacial layers between substrate and nanowire, 2nd a broad diameter (about 100 nm), and 3rd high density, and 4th critical evaporation temperature of Zinc precursors. In particular, the growth of high performance nanowire for high efficiency nano-devices must be formed at high temperature growth, but zinc precursors were evaporated at high temperature.These problems should be repaired for materialization of ultra high performance quantum devices with quantum effect. For this reason, we firstly proposed the growth method of vertical aligned slim MgZnO nanowires (< 10 nm) without interfacial layers using self-phase separation by introduced Mg at critical evaporation temperature of Zinc precursors ($500^{\circ}C$). Here, the self-phase separation was reported that MgO-rich and the ZnO-rich phases were spontaneously formed by additionally introduced Mg precursors. In the growth of nanowires, the nanowires were only grown on the wurzite single crystal seeds as ZnO-rich phases with relatively low Mg composition (~36 at %). In this study, we investigated the microstructural behaviors of self-phase separation with increasing the Mg fluxes in the growth of MZO NWs, in order to secure drastic control engineering of density,diameter, and shape of nanowires.

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유리기판 위에 Ag 후막의 마이크로웨이브 소결 (Microwave Sintering of Silver Thick Film on Glass Substrate)

  • 황성진;;;김형순
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2009년도 하계학술대회 논문집
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    • pp.22-22
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    • 2009
  • The silver thick film has been used in many industries such as display, chip, solar cell, automobile, and decoration with conventional heating. The silver thick film is fired with optimal time and temperature. However, decreasing the fabrication time is required due to high production power. Furthermore, there is a problem that silver in electrode is diffused throughout any substrates. For inhibiting the Ag diffusion and long fabrication time we considered a microwave heating. We investigated firing of silver thick film with conventional and microwave heating. The temperature of substrate was measured by thermal paper and the temperature of substrate was under $100\;^{\circ}C$ The shrinkage of electrode was measured with optical microscopy and optical profilometry. The shrinkage of electrode heat treated with microwave for 5min was similar to the that fired by the conventional heating for several hours. After firing by two types of heating, the diffusion of silver was determined using a optical microscope. The microstructure of sintered silver thick film was observed by SEM. Based on our results, the microwave heating should be a candidate heating source for the fabrication electronic devices in terms of saving the tact time and preventing the contamination of substrate.

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High Temperature Oxidation and Sulfidation of Ni-15at.%W Coatings

  • Kim Chanwou;You Teayoul;Shapovalov Yuriy;Ko Jaehwang;Lee Dongbok;Lee Kyuhwan;Chang Doyon;Kim Dongsoo;Kwon Sikchol
    • 한국표면공학회지
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    • 제38권1호
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    • pp.1-6
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    • 2005
  • Ni-15at.% W coatings with film thicknesses of 20-40 ㎛ were electroplated on a steel substrate, and their oxidation behavior was investigated at 700 and 800℃ in air. For comparison, a pure Ni coating and a bulk Ni were also oxidized. The Ni-15at.%W coating displayed the worst oxidation resistance, due to the formation of less-protective NiO, Fe₂O₃, NiFe₂O₄ and NiWO₄. The corrosion behavior Ni-15at.%W coatings electroplated on a steel substrate was similarly investigated at 700 and 800℃ in the Ar-l%SO₂ atmosphere. For comparison, the uncoated steel substrate was also corrosion-tested in the Ar-l %SO₂ atmosphere. Severe scale spallation and the internal corrosion of the steel that occurred in the uncoated substrate were not observed in the coated specimen. However, it seemed that the Ni-15at.%W coating cannot be a potential candidate as a sulfidation-resistant coating, due to the formation of less-protective NiO, NiS, WO₃ and NiWO₄.

열차폐코팅용 (La1-xGdx)2Zr2O7 산화물의 상형성과 열전도도 (Phase Evolution and Thermal Conductivities of (La1-xGdx)2Zr2O7 Oxides for Thermal Barrier Coatings)

  • 권창섭;이성민;오윤석;김형태;장병국;김성원
    • 한국분말재료학회지
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    • 제19권6호
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    • pp.429-434
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    • 2012
  • With increase in operating temperature of gas turbine for higher efficiency, it is necessary to find new materials of TBC for replacement of YSZ. Among candidate materials for future TBCs, zirconate-based oxides with pyrochlore and fluorite are prevailing ones. In this study, phase structure and thermal conductivities of $(La_{1-x}Gd_x)_2Zr_2O_7$ oxide system are investigated. $(La_{1-x}Gd_x)_2Zr_2O_7$ system are comprised by selecting $La^{3+}/Gd^{3+}$ as A-site ions and $Zr^{4+}$ as B-site ion in $A_2B_2O_7$ pyrochlore structures. With powder mixture from each oxide, $(La_{1-x}Gd_x)_2Zr_2O_7$ oxides are fabricated via solid-state reaction at $1600^{\circ}C$. Either pyrochlore or fluorite or mixture of both appears after heat treatment. For the developed phases along $(La_{1-x}Gd_x)_2Zr_2O_7$ compositions, thermal conductivities are examined, with which the potential of $(La_{1-x}Gd_x)_2Zr_2O_7$ compositions for TBC application is also discussed.

디젤엔진 배출가스 질소산화물 저감을 위한 Solid SCR의 반응률에 관한 연구 (A Study on Reaction Rate of Solid SCR for NOx Reduction of Exhaust Emissions in Diesel Engine)

  • 이호열;윤천석;김홍석
    • 한국자동차공학회논문집
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    • 제21권6호
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    • pp.183-194
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    • 2013
  • Liquid urea based SCR has been used in the market to reduce NOx in the exhaust emission of the diesel engine vehicle. This system has several problems at low temperature, which are freezing below $-12^{\circ}C$, solid deposit formation in the exhaust, and difficulties in dosing system at exhaust temperature below $200^{\circ}C$. Also, it is required complicated exhaust packaging equipment and mixer due to supply uniform ammonia concentration. In order to solve these issues, solid urea, ammonium carbonate, and ammonium carbamate are selected as ammonia sources for the application of solid SCR. In this paper, basic research on reaction rate of three ammonia-transporting materials was performed. TGA (Thermogravimetric Analysis) and DTA (Differential Thermal Analysis) tests for these materials are carried out for various heating conditions. From the results, chemical kinetic parameters such as activation energy and frequency factor are obtained from the Arrhenius plot. Additionally, from test results of DSC (Differential Scanning Calorimeter) for these materials, chemical kinetic parameters using the Kissinger method are calculated. Activation energies of solid SCR from this experiment are compared with proper data of literature study, then obtained data of this experiment are used for the design of reactor and dosing system for candidate vehicle.

강유전체 $(Bi,Nd)_4Ti_3O_{12}$ 박막의 결정 구조와 분극 특성 (Crystal Structure and Polarization Properties of Ferroelectric Nd-Substituted $Bi_4Ti_3O_{12}$ Thin Films Prepared by MOCVD)

  • 강동균;박원태;김병호
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2006년도 추계학술대회 논문집 Vol.19
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    • pp.135-136
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    • 2006
  • Bismuth titanate ($Bi_4Ti_3O_{12}$, BIT) thin film has been studied intensively in the past decade due to its large remanent polarization, low crystallization temperature, and high Curie temperature. Substitution of various trivalent rare-earth cations (such as $La^{3+}$, $Nd^{3+}$, $Sm^{3+}$ and $Pr^{3+}$) in the BIT structure is known to improve its ferroelectric properties, such as remanent polarization and fatigue characteristics. Among them, neodymuim-substituted bismuth titanate, ((Bi, Nd)$_4Ti_3O_{12}$, BNT) has been receiving much attention due to its larger ferroelectricity. In this study, Ferroelectric $Bi_{3.3}Nd_{0.7}Ti_3O_{12}$ thin films were successfully fabricated by liquid delivery MOCVD process onto Pt(111)/Ti/$SiO_2$/Si(l00) substrates. Fabricated polycrystailine BNT thin films were found to be random orientations, which were confirmed by X-ray diffraction and scanning electron microscope analyses. The remanent polarization of these films increased with increase in annealing temperature. And the film also demonstrated fatigue-free behavior up to $10^{11}$ read/write switching cycles. These results indicate that the randomly oriented BNT thin film is a promising candidate among ferroelectric materials useful for lead-free nonvolatile ferroelectric random access memory applications.

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