• Title/Summary/Keyword: cancer early detection

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Implementation of Digital Mammogram CAD Algorithm (디지털 유방영상의 CAD 알고리즘 구현)

  • Lee, Byungchea;Choi, Guirack;Jung, Jaeeun;Lee, Sangbock
    • Journal of the Korean Society of Radiology
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    • v.8 no.1
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    • pp.27-33
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    • 2014
  • Medical imaging has increased rapidly in the increase of interest in health, with the development of computer technology, digitization of medical imaging is rapidly advancing, PACS has been introduced to the medical field. Increase in the production of medical images by these phenomena made increased the workload of radiologist who must read a medical image. in response to the need for secondary diagnosis using a computer, The term of CAD in medical radiology field was introduced. In this study, we have proposed a CAD algorithm for the interpretation of the image obtained by the digital X-ray mammography equipment. The experiments were performed by programmed in Visual C++ for the proposed algorithm. A result of the execution of the CAD algorithm seven sample images, the results of five samples was confirmed in breast cancer and benign tumors, both the images sample was error processing. If you use a program that implements this with the algorithm proposed in this study it is helpful to reading breast images, and it is considered to contribute significantly to the early detection of breast cancer.

A Case of Ectopic Adrenocorticotropic Hormone Syndrome in Small Cell Lung Cancer

  • Jeong, Chaiho;Lee, Jinhee;Ryu, Seongyul;Lee, Hwa Young;Shin, Ah Young;Kim, Ju Sang;Ahn, Joong Hyun;Kang, Hye Seon
    • Tuberculosis and Respiratory Diseases
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    • v.78 no.4
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    • pp.436-439
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    • 2015
  • Small cell lung cancer (SCLC), which originated from neuroendocrine tissue, can develop into paraneoplastic endocrine syndromes, such as Cushing syndrome, because of an inappropriate secretion of ectopic adrenocorticotropic hormone (ACTH). This paraneoplastic syndrome is known to be a poor prognostic factor in SCLC. The reason for poor survival may be because of a higher risk of infection associated with hypercortisolemia. Therefore, early detection and appropriate treatment for this syndrome is necessary. But the diagnosis is challenging and the source of ACTH production can be difficult to identify. We report a 69-year-old male patient who had severe hypokalemia, metabolic alkalosis, and hypertension as manifestations of an ACTH-secreting small cell carcinoma of the lung. He was treated with ketoconazole and spironolactone to control the ACTH dependent Cushing syndrome. He survived for 15 months after chemotherapy, which is unusual considering the poor outcome of the ectopic ATH syndrome associated with SCLC.

Comprehensive Measures for Disease Prevention and Health Promotion (질병예방 및 건강증진 종합 대책)

  • 홍문식
    • Korean Journal of Health Education and Promotion
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    • v.8 no.1
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    • pp.5-13
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    • 1991
  • While the threat from traditional communicable diseases have been decreasing non communicable chronic diseases are increasing due to the aging of population and change in life pattern of the people such as over intake of cholesterol and lack of physical exercise etc. On the other hand, since 1980s, AIDS is spreading rapidly throughout the globe and environmental pollution, accidents, addictive diseases such as drug abuse and alcoholism are becoming serious factors to hinder the health promotion of the people. In order to improve general public health and promote individual health status, existing program for communicable disease control by the government such as tuberculosis, leprosy, STD and acute communicable diseases should be effectively continued. In principle, effort should be placed on eradication of source of infection, reduction of communicability of source in infection, treatment of source of infection as well as increase of individual registance to the diseases through immunization and improvement of physical status. Since the pattern of illness is being shifted from communicable diseases to non communicable chronic diseases such as cancer, cerebral hemorrhage, heart disease and hypertention etc., special emphasis should be placed on the prevention and control of those adult diseases. Early detection of the patients, registration and treatment of patients and health education should be systematically developed for effective control of the diseases. In addition, program activities on MCH, nutrition, dentistry, mental health, environmental health, accident prevention. medical delivery system, health insurance. and all other health issues should be improved in order to achieve our goal of health promotion.

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Management of Pharyngocutaneous Fistula Following Laryngectomy (후두적출술 후 발생한 인두피부누공의 치료 경험)

  • Min Hun-Ki;Kwon Soon-Young;Jung Kwang-Yoon;Choi Jong-Ouck
    • Korean Journal of Head & Neck Oncology
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    • v.11 no.2
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    • pp.167-172
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    • 1995
  • Pharyngocutaneous fistula(PCF) is one of the complications following total laryngectomy in laryngeal and hypopharyngeal cancer. Fistula lead to delayed wound healing, more serious complications such as carotid blow-out, prolonged hospitalization, significant patient morbidity and occasional mortality. Identification of patients at high risk for fistula formation, appropriate preventive measures, and appropriate management are the head and neck surgeon's responsibility. So we analyzed the clinical data of pharyngocutaneous fistula which was developed after total laryngectomy. Following results were obtained: 1) Occurrence of PCF increases with salvage surgery compared to curative surgery. 2) Early detection and effective management of PCF are the key factors to decreasing the hospitalization period. 3) Constructing a pharyngostoma seems to be an ideal method of preventing dangerous complications and ultimately closing the fistula. 4) Simultaneous reconstruction is necessary in the high risk group.

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Fully Automatic Liver Segmentation Based on the Morphological Property of a CT Image (CT 영상의 모포러지컬 특성에 기반한 완전 자동 간 분할)

  • 서경식;박종안;박승진
    • Progress in Medical Physics
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    • v.15 no.2
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    • pp.70-76
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    • 2004
  • The most important work for early detection of liver cancer and decision of its characteristic and location is good segmentation of a liver region from other abdominal organs. This paper proposes a fully automatic liver segmentation algorithm based on the abdominal morphology characteristic as an easy and efficient method. Multi-modal threshold as pre-processing is peformed and a spine is segmented for finding morphological coordinates of an abdomen. Then the liver region is extracted using C-class maximum a posteriori (MAP) decision and morphological filtering. In order to estimate results of the automatic segmented liver region, area error rate (AER) and correlation coefficients of rotational binary region projection matching (RBRPM) are utilized. Experimental results showed automatic liver segmentation obtained by the proposed algorithm provided strong similarity to manual liver segmentation.

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Microcalcification Extraction by Using Automatic Thredholding Based on Region Growing (영역 성장법을 기반으로 자동적인 임계치 설정을 이용한 미세 석회화 추출)

  • 원철호;권용준;이정현;박희준;임성운;김명남;조진호
    • Journal of Biomedical Engineering Research
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    • v.25 no.4
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    • pp.235-242
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    • 2004
  • In this paper, we proposed the algorithm for detection of microtalcification by automatic threshold decision based on region growing method. The region for optimal threshold is grown from local maximum pixel by increasing repeatedly threshold in microralcification candidate region. Then, the optimal threshold is automatically decided at the maximum value of the contrast and edge sharpness in this region. Microcalcifications could be efficiently detected as satisfied result that true positive ratio is 81.5% and average false positive numbers are 1.1 about total 299 microcalcifirations in real image. In a result, we showed that this algorithm can be used to aid diagnostic-radiologist for the diagnosis of the early phase of breast cancer.

Development of the Tailored Health Promotion Program for Rural Elderly: Based on the PRECEDE Model (농촌형 노인 건강증진프로그램 개발 연구: PRECEDE 모형을 중심으로)

  • Oh, Yun-Jung;Park, Jeong-Sook
    • Korean Journal of Health Education and Promotion
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    • v.22 no.4
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    • pp.179-202
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    • 2005
  • Purpose: The purpose of this study was to develop the health promotion program for rural elderly through PRECEDE process. Method: The health promotion program was developed based on the preliminary diagnosis. The data collection was performed from March 10th to April 9th, 2003. The subjects were selected at Mari Myun, Geochang Gun, in Korea. The preliminary diagnosis was examined with the 115 elders. Data was analyzed by descriptive statistics and Cronbach's n test with SPSS/Win 10.0 program. Results: The health promotion program was developed based on diagnostic result using PRECEDE model. The developed program was corrected and revised with the advices from 6 experts. The final program included health responsibility(cancer prevention and early detection, hygienic, false teeth management no smoking and moderation in drink, and chronic disease prevention and management), physical activity(6 kinds of exercise), nutrition(low sodium diet calcium intake, and right eating habit), spiritual growth(spiritual demand and death preparation teaching), interpersonal relations(relationship with couple, children, grandchildren, neighborhood), and stress management(sports dance, foot massage, positive thought, and song class). Conclusion: I propose that it is necessary to identity the effect of health promotion program for rural elderly. And strategy development that can spread the health promotion program elderly is needed.

Peutz-Jeghers Syndrome: A Case Report and Review of Literature (Peutz-Jeghers 증후군: 증례보고와 문헌고찰)

  • Kim, Hyun Soo;Kim, Soung Min;Choi, Jin Young;Myoung, Hoon;Lee, Suk Keun;Lee, Jong Ho
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.34 no.5
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    • pp.363-366
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    • 2012
  • Peutz-Jeghers syndrome is a rare syndrome with characteristic features of multiple hamartomatous polyps and mucocutaneous pigmentation. This syndrome is an autosomal dominant disease, and has complications related with polyps of the gastrointestinal tract, such as small bowel obstruction, iron deficiency anemia associated with bleeding, and intussusceptions. Many studies have reported about higher cancer risk of patients with this syndrome than those with no syndrome in the gastrointestinal tract, including gastric, duodenal, jejunal and the extragastrointestinal organs, such as gallbladder, breast and reproductive system. There are guidelines for periodic test for early detection and treatment for higher risk organs. We report a case of Peutz-Jeghers syndrome patient in the emphasis of Oral and Maxillofacial surgeon's role with review of the literature.

The Effect of Health Promotion Programs on Health Promoting Behavior and Cardiovascular Risk Factors of Middle-aged Women (건강증진프로그램이 중년기 여성의 건강증진행위와 심혈관계 위험요인에 미치는 영향)

  • Park, Jeong-Sook
    • Korean Journal of Adult Nursing
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    • v.14 no.2
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    • pp.233-243
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    • 2002
  • Purpose: This study is aimed at testing the effect of health promotion program on health promoting behavior and cardiovascular risk factors of middle-aged women. Method: The research design was the nonequivalent control group pre-post test. Twelve middle-aged women were the experimental group and ten were the control group. The 8-week health promotion program was given to the experimental group. There were health promotion theories, flexibility and muscle strength exercise, cardiopulmonary endurance exercise, nutrition, stress management, cancer prevention and early detection, management of menopause and wrap-up in health promotion program for middle-aged women. The measurement tool was Health Promoting Behavior developed by researcher using serum cholesterol, obesity rate, systolic blood pressure, and diastolic blood pressure as cardiovascular risk factors. Result: The experimental group showed a higher score of health promoting behavior than the control group. There were no differences on cardiovascular risk factors(cholesterol, obesity rate, diastolic blood pressure) between the experimental and control groups except systolic blood pressure. Conclusion: Conclusively, this health promotion program for middle-aged women was effective in increasing health promotion behaviors, but wasn't effective in decreasing cardiovascular risk factors except the systolic blood pressure. It seems it's necessary to re-study this using more samples and a longer duration of the program, and smaller mortality rate.

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The Effect of Work-site Health Promotion Program on Health Promoting Behavior, Cholesterol, and the Quality of Life of Middle-aged Workers (산업장 건강증진프로그램이 중년기 근로자의 건강증진행위, 콜레스테롤치 및 삶의 질에 미치는 영향)

  • Park, Jeong-Sook;Park, Kyung-Min
    • Korean Journal of Adult Nursing
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    • v.14 no.2
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    • pp.194-204
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    • 2002
  • Purpose: This study is aimed at showing the effect of work-site health promotion programs for health promoting behavior, cholesterol, and quality of life of middle-aged workers. Method: Thirty-one middle-aged workers were the experimental group and thirty-one were the control group. The 8-week work-site health promotion program was given to the experimental group. After this, health promoting behavior, cholesterol and quality of life were measured by questionnaires for the experimental and control groups. Health promotion theory, flexibility and muscle strength, aerobic exercise, nutrition, stress management, cancer prevention and early detection, smoking and alcohol problems, and summary lecture were all included in the 8-week work-site health promotion program. Health promoting behavior was measured by Park's HPBS, cholesterol was measured by enzyme method, and quality of life was measured by Ro's QOL. Result: The experimental group showed a higher score of health promoting behavior than the control group. There were no differences on cholesterol and quality of life between the experimental and control groups. Conclusion: It is necessary that nurses provide middle-aged workers with work-site health promotion programs to improve health promoting behavior. It's necessary also to re-study this with the pre-post research design.

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