• Journal of the Korean Dietetic Association
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• v.27 no.3
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• pp.179-190
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• 2021

The high caffeine intake by adolescents has been a concern. The purpose of this study was to examine the awareness and consumption of caffeine-containing foods among 443 high school students using a questionnaire. An analysis of the spending patterns of the students' weekly allowance showed that the amounts spent on purchasing caffeine-containing foods were higher for female students than male students (P <0.001). The scoring of the perception of caffeine was 3.1 out of 5, interest in the caffeine content of food was 2.6, consumption of caffeine-containing foods was 2.6, and usefulness of caffeine-containing foods was 2.7. The awareness of caffeine content in food was significantly higher in females (7.3 out of 11) than male students (6.7) (P<0.01). Approximately 59% of students perceived that the relationship between caffeine-containing foods and health, was harmful, and the experience of side effects after taking caffeine was significantly higher in female students than males. These side effects include heartburn (P<0.001), headache or dizziness (P<0.001), irregular heartbeat (P<0.05), and hands and feet shake (P<0.01). Caffeine-containing foods were purchased at convenience stores (62.1%). The factor considered when purchasing caffeine-containing foods was taste (72.2%), and the use of nutrition labeling for caffeine-containing foods scored 2.0 out of 5 points. When assessing the intake of caffeine-containing foods, the foods consumed more than once a week were in the order of coke, chocolate, chocolate milk, chocolate pie, and chocolate bars. These results suggest that it is necessary to prepare a caffeine-related nutrition guide improvement by sales management, and strengthen food labeling standards for the desirable recognition of caffeine and its safe intake by adolescents.

• Journal of the Korean Society of Food Culture
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• v.39 no.3
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• pp.127-137
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• 2024

This study examined dietary habits and mental health according to generalized anxiety disorders (GAD) and caffeine consumption in adolescents. The data were collected from the 18^th Korea Youth Risk Behavior Survey with a sample of 51,850 students. The proportion of students in the GAD High-Risk·Caffeine consumption group (GHRCC) who consumed sweet drinks (p< .001), fast food (p< .001), and midnight meals (p< .001) every day was 15.6, 21.9, and 22.4%, respectively. These proportions were higher than those of students who consumed sweet drinks, fast food, and midnight meals 1-2 times a week, 3-4 times a week, or not at all. In addition, the proportions of GHRCC among students who responded "yes" to experiencing sadness and despair (p< .001), suicidal thoughts (p< .001), suicide plans (p< .001), suicide attempts (p< .001), and loneliness (p< .001) were higher than students who responded "no." The GAD High-Risk group (GHR) had higher odds with the consumption of midnight meals (OR: 2.51, 95% CI: 2.10-2.99), caffeine consumption (OR: 2.46, 95% CI: 2.21-2.74), and fast food (OR: 2.11, 95% CI: 1.75-2.55) than GAD Low-Risk group. Based on the above results, the risk of GHR was higher among students who consumed midnight meals, caffeine, and fast food daily than those who did not.

• Korean Journal of Community Nutrition
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• v.23 no.4
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• pp.289-301
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• 2018

Objectives: The aim of this study was to examine the current status of consumption of energy drinks among college students and investigate the effects of general environmental factors, health behavior factors, caffeine knowledge levels, and perceived stress levels on consumption of energy drinks. Methods: A survey was conducted among a total of 479 college students in Gwangju, using self-administered questionnaires. The questionnaire consisted of items about general environmental factors, health behavior, caffeine knowledge, perceived stress, and energy drink consumption behaviors. Results: 69.1% of participants experienced consumption of energy drinks, and specifically 82.8% of male students and 54.1% of female students experienced consumption of energy drinks (p<0.001). The reasons for drinking energy drinks were found to be recovery from fatigue, curiosity, taste, habit, thirst relief, and stress relief. In addition, 40.7% of participants experienced drinking energy drinks mixed with alcohol, and specifically 48.6% of male students and 27.4% of female students reported drinking energy drinks with alcohol (p<0.001). Moreover, 51.5% of participants responded that they experienced the effects of energy drinks, 31.9% reported experiencing adverse effects, and 41.1% were found to perceive the health risks. As a result of the assessment of caffeine knowledge, the participants showed a high level of knowledge of the arousal effect (77.7%) and the concentration increasing effect (70.8%) of caffeine, whereas they exhibited a low level of understanding of the health problems due to caffeine (32.6%) and adequate caffeine intake levels (24.4%). The higher levels of consumption experience of energy drinks was associated with higher body mass indexes (BMI) (p<0.01), higher academic years (p<0.01), lower levels of interest in health (p<0.05), smoking (p<0.001), alcohol consumption (p<0.05), and higher levels of perceived stress (p<0.05). Conclusions: The risk groups related to consumption of energy drinks among college students were identified as male students rather than female students, students in the third or fourth year of study associated with increased stress levels, and students with negative health behaviors. Therefore, support for diverse health and nutrition education for college students is required along with the improvement of internal and external environments of schools in order for college students to manage increased stress levels due to the schoolwork and preparation for employment and maintain positive health behaviors.

• Korean Journal of Agricultural Science
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• v.46 no.4
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• pp.981-989
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• 2019

Coffee is a popular beverage worldwide, and the scale of consumption is growing rapidly. Many studies have shown that increased coffee consumption has various effects on human health, including beneficial effects on liver diseases, clinical type 2 diabetes, and Parkinson's disease. However, the influences of coffee or caffeine (a component of coffee) on the gut microbiota have not been examined in detail. Here, we tested whether caffeine could alter the antimicrobial activity of L. casei against E. coli. Interestingly, we found that treatment with 0.3 mg/mL caffeine increased the antimicrobial activity of L. casei against E. coli. This activity was not associated with the release of lactic acid but did appear to be related to a heat-labile factor present in the L. casei culture supernatant. Our analyses suggest that the putative antimicrobial factor found in the culture supernatant of L. casei treated with caffeine may be bacteriocin. Taken together, our results suggest that caffeine, which is an ingredient of coffee, increases the antimicrobial activity of L. casei against E. coli through the enhanced production of bacteriocin. These findings also suggest that coffee consumption affects the ability of beneficial bacteria to decrease pathogenic bacteria and/or prevent the progression of bacterial infection-associated diseases in the gut.

• Journal of Korean Biological Nursing Science
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• v.21 no.3
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• pp.217-223
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• 2019

Purpose: Caffeine is the most widely consumed psychostimulant of the methylxanthine class. Among adolescents, high-dose of caffeine consumption has increased rapidly over the last few decades due to the introduction of energy drinks. However, little is known about the time-dependent effect of high doses of caffeine consumption in adolescents. The present study aims to examine the short- and long-term influence of high-dose caffeine on behavior of adolescence. Methods: The animals were divided into three groups: a "vehicle" group, which was injected with 1 ml of phosphate-buffered saline for 14 days; a "Day 1" group, which was injected with caffeine (30 mg/kg), 2 h before the behavioral tests; and a "Day 14" group, which was infused with caffeine for 14 days. An open-field test, a Y-maze test, and a passive avoidance test were conducted to assess the rats'activity levels, anxiety, and cognitive function. Results: High-dose caffeine had similar effects in short-and long-term treatment groups. It increased the level of locomotor activity and anxiety-like behavior, as evidenced by the increase in the number of movements and incidences of rearing and grooming in the caffeine-treated groups. No significant differences were observed between the groups in the Y-maze test. However, in the passive avoidance test, the escape latency in the caffeine-treated group was decreased significantly, indicating impaired memory acquisition. Conclusion: These results indicate that high-dose caffeine in adolescents may increase locomotor activity and anxiety-like behavior and impair learning and memory, irrespective of the duration of administration. The findings will be valuable for both evidence-based education and clinical practice.

• Korean Parent-Child Health Journal
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• v.8 no.2
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• pp.147-156
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• 2005

Purpose: The purpose of this study was the influencing variables of maternal weight gain and neonatal birth weight in full term pregnancies. Method: The subjects were 136 mothers in full term pregnancies(38-42 weeks) and her babies who were selected from 2 general hospital in Pusan. The data were collected from June 14th to October 14th in 2004. Data were obtained by questionnaires. Results: The maternal weight gains was lesser that the pregravid weights was the lower (F=3.410, p=.011). The volumes of weight gains of mothers that had alcohol drinking(t=6.259, p=.014), caffeine consumption (t=4.137, p=.044) were lesser than not. And the birth weight were influenced by passive smoking(t=4.017, p=.047), caffeine consumption (t=5.954, p=.016). Conclusion: The results of this research confirm that the maternal weight gains were influenced by pregravid weight, alcohol drink, caffeine consumption. And the birth weight were influenced by passive smoking, caffeine consumption.

• Journal of Convergence for Information Technology
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• v.9 no.6
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• pp.35-43
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• 2019

This study was conducted in order to identify consumption and experience of adverse effects of high-caffeine energy drink among high school students. This study was a descriptive survey including 245 students in D city. Data were analyzed using descriptive statistics and ${\chi}^2$ test. In the results, 79.5% of the students had previous experience of energy drink consumption. 50.6% of students were experienced adverse effects, mainly palpitation. Among the general characteristics, there was a significant difference according to the experience of high-caffeine energy drink consumption depending on monthly allowance(p=.019) and drinking(p=.033), and a significant difference from adverse effects depending on gender(p=.001) and health condition(p=.006). Also, there was a significant difference according to the experience of adverse effects depending on drinking reason(p=.040) and drinking time(p=.005). After, policy measures are needed to limit the sale of high-caffeine energy drinks and continuous health education is needed to foster the ability of students to control themselves.

• YAKHAK HOEJI
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• v.37 no.4
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• pp.341-349
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• 1993

To determine the reason of individual variation of the effect of caffeine, the absorption and the disposition of caffeine were studied in caffeine sensitive and caffeine nonsensitive volunteers. And also to study the effect of obesity on caffeine pharmacokinetics, the caffeine disposition in the obese rat and in the lean rat were investigated respectively. In result the caffeine sensitive group showed a longer terminal half-life of caffeine(7.35$\pm$0.71 hr : 5.49$\pm$0.73 hr) and a larger AUC (55.42$\pm$9.09 $\mu\textrm{g}$.$ml^{-1}$.hr:44.0$\pm$7.81$\mu\textrm{g}$.$ml^{-1}$.hr) than that of caffeine non-sensitive group without statistical significance. The obese rat showed a longer terminal half-life (3.47 hr : 2.31 hr) and a larger AUC(35.3 $\mu\textrm{g}$.$ml^{-1}$.hr:26.97$\mu\textrm{g}$.$ml^{-1}$.hr) than that of the lean rat. But there was no correlation in the amount of daily caffeine consumption and obesity. In conclusion, we suggest that the individual variation of the effect of caffeine are being caused from the individual differences of caffeine susceptibility or tolerance rather than the differences of the genetic metabolic capacity or metabolic tolerance.

• Journal of Life Science
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• v.12 no.4
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• pp.375-382
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• 2002

The purpose of this experiment was to examine influence of acute exercise on nocturnal sleep which had been disrupted by caffeine(400mg$\times$3) thought the daytime. Six healthy young males aged 21.0$\times$0.2 yr with a history of low caffeine use. Subjects completed three conditions in a within-subject. At three conditions Sleep EEG were investigated: (1) nocturnal following quiet rest, (2) nocturnal sleep following the consumption of 1200mg of caffeine (3) nocturnal sleep following cycling at 60 min of 60% V $O_{2peak}$ with 1200mg of caffeine consumption. Sleep data were calculated for REM sleep, REM latency, sleep onset latency, sleep efficiency, sleep stages, SWS. Those data were analyzed using repeated-measures ANOVA of change scores. A main effect to, drug(caffeine) indicated that caffeine elicited sleep disturbance that is, TST and sleep onset latency increase and sleep efficiency and stage 4 decrease. The effects of exercise on sleep following caffeine intake generally improve sleep that is, stage 2, 3 and SWS increase and sleep onset latency decrease. A condition effect for sleep indicated sleep improvement after exercise Therefore The data supported a restorative theory of slow-wave sleep and suggest that acute exercise may be useful in promoting sleep and reducing sleep disturbance elevated by a high dose of caffeine.

• Clinical and Experimental Reproductive Medicine
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• v.39 no.4
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• pp.144-152
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• 2012

Objective: Concerns are growing about the decrease in male reproductive health. Caffeine is one of the popular nutrients that has been implicated as a risk factor for infertility. In the present study, we examined whether in utero and lactational exposure to caffeine affects the reproductive function of the offspring of rats. Methods: Pregnant rats received caffeine via drinking water during gestation (26 and 45 mg/kg) and lactation (25 and 35 mg/kg). Body and reproductive organ weight, seminiferous tubule diameter, germinal epithelium height, sperm parameters, fertility rate, number of implantations, and testosterone level of the offspring were assessed from birth to adulthood. Results: Significant dose-related decreases were observed in the body and reproductive organ weight, seminiferous tubule diameter, and germinal epithelium height of the offspring. Sperm density had declined significantly in offspring of the low-dose and high-dose groups, by 8.81% and 19.97%, respectively, by postnatal day 150. The number of viable fetuses had decreased significantly in females mated with male offspring of the high-dose group at postnatal days 60, 90, 120, and 150. There were also significant reductions in testosterone levels of high-dose group offspring from birth to postnatal day 150. Conclusion: It is concluded that maternal caffeine consumption impairs gonadal development and has long-term adverse effects on the reproductive efficiency of male offspring rats.