• Title/Summary/Keyword: build-up region

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Geant4 Code Based Simulation of 6 MV Photon Beam for Analysis of Dose Distribution (Geant4 코드를 이용한 선형가속기 6 MV 광자선의 선량분포에 관한 연구)

  • Lee, Jun-Seong;Kim, Yang-Soo;Lee, Sun-Young
    • Journal of radiological science and technology
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    • v.45 no.5
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    • pp.449-455
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    • 2022
  • This study is to present a Geant4 code for the simulation of the absorbed dose distribution given by a medical linac for 6 MV photon beam. The dose distribution was verified by comparison with calculated beam data and beam data measured in water phantom. They were performed for percentage depth dose(PDD) and beam profile of cross-plane for two field sizes of 10 × 10 and 15 × 15 cm2. Deviations of a percentage and distance were obtained. In energy spectrum, the mean energy was 1.69 MeV. Results were in agreement with PDD and beam profile of the phantom with a tolerance limit. The differences in the central beam axis data 𝜹1 for PDD had been less than 2% and in the build up region, these differences increased up to 4.40% for 10 cm square field. The maximum differences of 𝜹2 for beam profile were calculated with a result of 4.35% and 5.32% for 10 cm, 15 cm square fields, respectively. It can be observed that the difference was below 4% in 𝜹3 and 𝜹4. For two field sizes of 𝜹50-90 and RW50, the results agreed to within 2 mm. The results of the t-test showed that no statistically significant differences were found between the data for PDD of 𝜹1, p>0.05. A significant difference on PDD was observed for field sizes of 10 × 10 cm2, p=0.041. No significant differences were found in the beam profile of 𝜹3, 𝜹4, RW50, and 𝜹50-90. Significant differences on beam profile of 𝜹2 were observed for field sizes of 10 × 10 cm2, p=0.025 and for 15 × 15 cm2, p=0.037. This work described the development and reproducibility of Geant4 code for verification of dose distribution.

History of Land Registration and Small House Policies in the New Territories of the Hong Kong Special Administrative Region, the People's Republic of China

  • Fung, Philip Sing-Sang;Lee, Almond Sze-Mun
    • Land and Housing Review
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    • v.5 no.1
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    • pp.53-56
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    • 2014
  • Hong Kong, a well-known metropolis characterized by skyscrapers on both sides of the Victoria Harbour, consists mainly of 3 parts, namely the Hong Kong Island, the Kowloon peninsula and the New Territories (N.T.) which is the land area north of Kowloon plus a number of outlying islands. Located in the N.T. are all the new towns, market towns; and in the plains and valleys lie scattered village houses of not more than 3 storeys within the confines of well-defined village. These village houses are governed by a rural housing policy that could be traced back to the very beginning of the former British administration in the N.T. By the Convention of Peking of 1898, the N.T., comprising the massive land area north of Kowloon up to Shenzhen River and 235 islands, was leased to Britain by China for 99 years from 1st July 1898. Soon after occupation, the colonial government conducted a survey of this uncharted territory from 1899 to 1903, and set up a land court to facilitate all land registration work and to resolve disputed claims. By 1905, the Block Crown Leases with Schedule of Lessees and details of the lots, each with a copy of the lot index plan (Demarcation Plan) were executed. Based on the above, Crown rent rolls were prepared for record and rent collection purposes. All grants of land thereafter are known as New Grant lots. After completion and execution of the Block Crown Lease in 1905, N.T. villagers had to purchase village house lots by means of Restricted Village Auctions; and Building Licences were issued to convert private agricultural land for building purposes but gradually replaced by Land Exchanges (i.e. to surrender agricultural land for the re-grant of building land) from the early 1960's until introduction of the current Small House Policy in October 1972. It was not until the current New Territories Small House Policy came into effect in December 1972 that the Land Authority can make direct grant of government land or approve the conversion of self-owned agricultural land to allow indigenous villagers to build houses within the village environs under concessionary terms. Such houses are currently restricted to 700 square feet in area and three storeys with a maximum height of 27 feet. An indigenous villager is a male descendent of a villager who was the resident of a recognized village already existing in 1898. Each villager is only allowed one concessionary grant in his lifetime. Upon return of Hong Kong to the People's Republic of China on July 1st, 1997, the traditional rights of indigenous villagers are protected under Article 40 of the Basic Law (a mini-constitution of the Hong Kong Special Administrative Region). Also all N.T. leases have been extended for 50 years up to 2047. Owing to the escalating demand and spiral landed property prices in recent years, abuse of the N.T. Small House Policy has been reported in some areas and is a concern in some quarters. The Hong Kong Institute of Land Administration attempts to study the history that leads to the current rural housing policy in the New Territories with particular emphasis on the small house policy, hoping that some light can be shed on the "way forward" for such a controversial policy.

Characteristics of 15 MV Photon Beam from a Varian Clinac 1800 Dual Energy Linear Accelerator (CLINAC 1800 선형가속기의 15 MV X-선의 특성)

  • Kim, Kye-Jun;Lee, Jong-Young;Park, Kyung-Ran
    • Radiation Oncology Journal
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    • v.9 no.1
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    • pp.131-141
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    • 1991
  • A comprehensive set of dosimetric measurements has been made on the Varian Clinac 1800 15 MV photon beam. Beam quality, percentage depth dose, dose in the build up region, output, symmetry and flatness, transmission through iead (Cerrobend), tray attenuation, isodose curves for the open and wedged fields were measured using 3 dimensional water phantom dosimetry system (including film densitometer system) and polystyrene phantoms. These dosimetric measurements sufficiently characterized the beam to permit clinical use. The depth dose characteristics of photon beam is $d_{max}$ of 3.0 cm and percentage depth dose of $76.8\%$ at 10 cm,100 cm source-surface distance, field size of $10\times10\;cm^2$ for 15 MV X-ray beam. The Output factors ranged 0.927 for $4\times4\;cm^2$ field to 1,087 for $35\times35\;cm^2$ field. The build-up level of maximum dose was at 3.0 cm and surface dose was approximately $15.5\%$ for a field size $10\times10\;cm^2$ The stability of output is $within\pm1\%$ and flatness and symmetry are $within\pm3\%$. The half value thickness (HVL) of lead is 13 mm, which corresponds to an attenuation coefficient of $0.053\;mm^{-1}$. These figures compare facorably with the manufacturesr`s specifications.

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Crop Injury (Growth Inhibition) Induced by Herbicides and Remedy to Reduce It (제초제(除草劑) 약해발생(藥害發生) 양상(樣相)과 경감대책(輕減對策))

  • Kim, K.U.
    • Korean Journal of Weed Science
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    • v.12 no.3
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    • pp.261-270
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    • 1992
  • Many herbicides that are applied at the soil before weed emergence inhibit plant growth soon after weed germination occurs. Plant growth has been known as an irreversible increase in size as a result of the processes of cell divison and cell enlargement. Herbicides can influence primary growth in which most new plant tissues emerges from meristmatic region by affecting either or both of these processes. Herbicides which have sites of action during interphase($G_1$, S, $G_2$) of cell cycle and cause a subsequent reduction in the observed frequency of mitotic figures can be classified as an inhibitor of mitotic entry. Those herbicides that affect the mitotic sequence(mitosis) by influencing the development of the spindle apparatus or by influencing new cell plate formation should be classified as causing disruption of the mitotic sequence. Sulfonylureas, imidazolinones, chloroacetamides and some others inhibit plant growth by inhibiting the entry of cell into mitosis. The carbamate herbicides asulam, carbetamide, chlorpropham and propham etc. reported to disrupt the mitotic sequence, especially affecting on spindle function, and the dinitroaniline herbicides trifluralin, nitralin, pendimethalin, dinitramine and oryzalin etc. reported to disrupt the mitotic sequence, particularly causing disappearence of microtubles from treated cells due to inhibition of polymerization process. An inhibition of cell enlargement can be made by membrane demage, metabolic changes within cells, or changes in processes necessary for cell yielding. Several herbicides such as diallate, triallate, alachlor, metolachlor and EPTC etc. reported to inhibit cell enlargement, while 2, 4-D has been known to disrupt cell enlargement. One potential danger inherent in the use of soil acting herbicides is that build-up of residues could occur from year to year. In practice, the sort of build-up that would be disastrous is unikely to occur for substances applied at the correct soil concentration. Crop injury caused by soil applied herbicides can be minimized by (1) following the guidance of safe use of herbicides, particularly correct dose at correct time in right crop, (2) by use of safeners which protect crops against injury without protecting any weed ; interactions between herbicides and safeners(antagonists) at target sites do occur probably from the following mechanisms (1) competition for binding site, (2) circumvention of the target site, and (3) compensation of target site, and another mechanism of safener action can be explained by enhancement of glutathione and glutathione related enzyme activity as shown in the protection of rice from pretilachlor injury by safener fenclorim, (3) development of herbicide resistant crops ; development of herbicide-resistant weed biotypes can be explained by either gene pool theory or selection theory which are two most accepted explanations, and on this basis it is likely to develop herbicide-resistant crops of commercial use. Carry-over problems do occur following repeated use of the same herbicide in an extended period of monocropping, and by errors in initial application which lead to accidental and irregular overdosing, and by climatic influence on rates of loss. These problems are usually related to the marked sensitivity of the particular crops to the specific herbicide residues, e.g. wheat/pronamide, barley/napropamid, sugarbeet/ chlorsulfuron, quinclorac/tomato. Relatively-short-residual product, succeeding culture of insensitive crop to specific herbicide, and greater reliance on postemergence herbicide treatments should be alternatives for farmer practices to prevent these problems.

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Comparative Studies on Absorbed Dose by Geant4-based Simulation Using DICOM File and Gafchromic EBT2 Film (DICOM 파일을 사용한 Geant4 시뮬레이션과 Gafchromic EBT2 필름에 의한 인체 내 흡수선량 비교 연구)

  • Mo, Eun-Hui;Lee, Sang-Ho;Ahn, Sung-Hwan;Kim, Chong-Yeal
    • Progress in Medical Physics
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    • v.24 no.1
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    • pp.48-53
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    • 2013
  • Monte Carlo method has been known as the most accurate method for calculating absorbed dose in the human body, and an anthropomorphic phantom has been mainly used as a method of simulating internal organs for using such a calculation method. However, various efforts are made to extract data on several internal organs in the human body directly from CT DICOM files in recent Monte Carlo calculation using Geant4 code and to use by converting them into the geometry necessary for simulation. Such a function makes it possible to calculate the internal absorbed dose accurately while duplicating the actual human anatomical structure. Thus, this study calculated the absorbed dose in the human body by using Geant4 associating with DICOM files, and aimed to confirm the usefulness by compare the result with the measured dose using a Gafchromic EBT2 film. This study compared the dose calculated using simulation and the measured dose in beam central axis using the EBT2 film. The results showed that the range of difference was an average of 3.75% except for a build-up region, in which the dose rapidly changed from skin surface to the depth of maximum dose. In addition, this study made it easy to confirm the target absorbed dose by internal organ and organ through the output of the calculated value of dose by CT slice and the dose value of each voxel in each slice. Thus, the method that outputs dose value by slice and voxel through the use of CT DICOM, which is actual image data of human body, instead of the anthropomorphic phantom enables accurate dose calculations of various regions. Therefore, it is considered that it will be useful for dose calculation of radiotherapy planning system in the future. Moreover, it is applicable for currently-used several energy ranges in current use, so it is considered that it will be effectively used in order to check the radiation absorbed dose in the human body.

The Variation of Surface Dose by Beam Spoiler in 10 MV Photon Beam from Linear Accelerator (선형가속기 10 MV 광자선에서 산란판(Beam Spoiler) 사용 시 표면선량 변화)

  • Bae, Seong-Cheol;Kim, Jun-Ho;Lee, Choul-Soo
    • The Journal of Korean Society for Radiation Therapy
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    • v.18 no.1
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    • pp.21-28
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    • 2006
  • Purpose: The purpose of this study is to find a optimal beam spoiler condition on the dose distribution near the surface, when treating a squamous cell carcinoma of the head and neck and a lymphatic region with 10 MV photon beam. The use of a optimal spoiler allows elivering high dose to a superficial tumor volume, while maintaining the skin-sparing effect in the area between the surface to the depth of 0.4 cm. Materials and Methods: The lucite beam spoiler, which were a tissue equivalent, were made and placed between the surface and the photon collimators of linear accelerator. The surface-dose, the dose at the depth of 0.4 cm, and the maximum dose at the dmax were measured with a parallel-plate ionization chamber for $5{\times}5cm\;to\;30{\times}30cm^2$ field sizes using lucite spoilers with different thicknesses at varying skin-to-spoiler separation (SSS). In the same condition, the dose was measured with bolus and compared with beam spoiler. Results: The spoiler increased the surface and build-up dose and shifted the depth of maximum dose toward the surface. With a 10 MV x-ray beam and a optimal beam spoiler when treating a patient, a similer build-up dose with a 6 MV photon beam could be achieved, while maintaining a certain amount of skin spring. But it was provided higher surface dose under SSS of less than 5 cm, the spoiler thickness of more than 1.8 cm or more, and larger field size than $20{\times}20cm^2$ provided higher surface dose like bolus and obliterated the spin-sparing effect. the effects of the beam spoiler on beam profile was reduced with increasing depths. Conclusion: The lucite spoiler allowed using of a 10 MV photon beam for the radiation treatment of head and neck caner by yielding secondary scattered electron on the surface. The dose at superficial depth was increased and the depth of maximum dose was moved to near the skin surface. Spoiling the 10 MV x-ray beam resulted in treatment plans that maintained dose homogeneity without the consequence of increased skin reaction or treat volume underdose for regions near the skin surface. In this, the optimal spoiler thickeness of 1.2 cm and 1.8 cm were found at SSS of 7 cm for $10{\times}10cm^2$ field. The surface doses were measured 60% and 64% respectively. In addition, It showed so optimal that 94% and 94% at the depth of 0.4 cm and dmax respectively.

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Near Infrared Spectroscopy for Diagnosis: Influence of Mammary Gland Inflammation on Cow´s Milk Composition Measurement

  • Roumiana Tsenkova;Stefka Atanassova;Kiyohiko Toyoda
    • Near Infrared Analysis
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    • v.2 no.1
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    • pp.59-66
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    • 2001
  • Nowadays, medical diagnostics is efficiently supported by clinical chemistry and near infrared spectroscopy is becoming a new dimension, which has shown high potential to provide valuable information for diagnosis. The investigation was carried out to study the influence of mammary gland inflammation, called mastitis, on cow´s milk spectra and milk composition measured by near infrared spectroscopy (NIRS). Milk somatic cell counts (SCC) in milk were used as a measure of mammary gland inflammation. Naturally occurred variations with milk composition within lactation and in the process of milking were included in the experimental design of this study. Time series of unhomogenized, raw milk spectral data were collected from 3 cow along morning and evening milking, for 5 consecutive months, within their second lactation. In the time of the trial, the investigated cows had periods with mammary gland inflammation. Transmittance spectra of 258 milk samples were obtained by NIRSystem 6500 spectrophotometer in 1100-2400 nm region. Calibration equations for the examined milk components were developed by PLS regression using 3 different sets of samples: samples with low somatic cell count (SCC), samples with high SCC and combined data set. The NIR calibration and prediction of individual cow´s milk fat, protein, and lactose were highly influenced by the presence of mil samples from animals with mammary gland inflammation in the data set. The best accuracy of prediction (i.e. the lower SEP and the higher correlation coefficient) for fat, protein and lactose was obtained for equations, developed when using only “healthy” samples, with low SCC. The standard error of prediction increased and correlation coefficient decreased significantly when equations for low SCC milk were used to predict examined components in “mastitis” samples with high SCC, and vice versa. Combined data set that included samples from healthy and mastitis animals could be used to build up regression models for screening. Further use of separate model for healthy samples improved milk composition measurement. Regression vectors for NIR mild protein measurement obtained for “healthy” and “mastitic” group were compared and revealed differences in 1390-1450 nm, 1500-1740 nm and 1900-2200 nm regions and thus illustrated post-secretory breakdown of milk proteins by hydrolytic enzymes that occurred with mastitis. For the first time it has been found that monitoring the spectral differences in water bands at 1440 nm and 1912 nm could provide valuable information for inflammation diagnosis.

A Study on the Effects of Wedge Filter in Peripheral Dose Distribution (Wedge Filter가 주변선량분포에 주는 영향에 관한 연구)

  • Kang, Wee-Saing;Kim, Il-Han;Park, Charn-Il
    • Radiation Oncology Journal
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    • v.3 no.2
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    • pp.145-151
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    • 1985
  • The peripheral dose distributions of wedge fields of Co-60 $\gamma-ray$ and 1 OMV x-ray were measured by the solid state detector controlled by means of semiautomatic water phentom system. The measurements were made on the principal plane parallel to the cross section of wedge filter (blade and ridge direction). For parallel motion of the detector to the beam axis the distance from the margin of radiation field at suface were 3, 5 and 10cm. For tranverse motion the depth of measurement were dm, 5, 10 and 15cm. The followings were drawn from the measurement. 1. The peripheral dose of the blade side of wedges was generally higher than that of the ridge side at symmetric point about beam axis. 2. In the superficial region phenomena of dose build-up appeared. 3. For Co-60 $\gamma-ray$ field, the peripheral dose did not monotonously decrease with the distance from the field margin but increase in some range, consequently showing a peak dose. 4. The peripheral dose did not only depend on radiation quality and field size, but also on wedge angle and wedge direction.

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Enrollment Elevation to the Chinese International Students in Local Universities in Korea (한국 지방대학의 중국유학생 유치·관리방안)

  • Chung, Kyoun-Sup;Lei, Song-Lin;Sim, Moon-Bo
    • The Journal of the Korea Contents Association
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    • v.10 no.8
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    • pp.327-340
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    • 2010
  • Since South Korea has problems existing in the respects of educational resources, environment, policies, etc., local universities of South Korea have been in an inferior position in the competition of overseas student enrollment. With increasingly deepening of cultural exchange between China and South Korea, due to geographic close relationship between the two countries, a great number of South Korean students go to China for study; also, Chinese students have increasingly become the important target of recruitment by all local universities in South Korea. In recent years, with rapid increase in the number of Chinese students in South Korea, the overseas student education system of South Korea has been progressed continuously. Compared with educational advantages of universities in European, American developed countries, and the capital region of South Korea, however there still exists a lot of problems in Chinese student recruitment by local universities. The major findings of the study can be summarized as follows. There exist not only some advantages but also some problems to be addressed urgently in Chinese student enrollment by South Korean local universities. How to build a distinctive recruitment environment suitable for Chinese students; and, how to develop a complete "one-stop" educational system suitable for study; and, how to make a strategy of development for Chinese students; and, how to perfect set up the overseas students' education management system; which are the remaining tasks to be solved for. To achieve a win-win for both overseas students and South Korean local universities, it is very important and urgent works to do for administrators of Chinese students in all local universities of South Korea.

Prediction Model of Suicidal Ideation in Elderly Men Living Alone Based on Ecological System Theory (생태학적 체계이론에 기반한 남자독거노인의 자살생각 예측모형)

  • Hong, Si Myung
    • Journal of agricultural medicine and community health
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    • v.42 no.2
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    • pp.57-68
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    • 2017
  • Objectives: This study was performed to build the predictive model of suicidal ideation of elderly men living alone. Methods: As for the subject, 251 subjects suitable for the selection criteria were selected among elderly men living alone above 65 years old in one region in Gyeongnam and three regions in Gyeongbuk. The data were collected via questionnaires and analyzed using SPSS version 20.0 and Amos version 18.0. Results: The goodness-of-fit test result of hypothetical model were suitable for recommended level: ${\chi}^2/df=1.47$, RMR=.04, GFI=.92, AGFI=.90, CFI=.95, IFI=.95, RMSEA=.04. Self-esteem, individual coping, family cohesion, social support, social activity, and depression explained 55% of the model of suicidal ideation. The most influential direct factor of suicidal ideation was self-esteem, and social isolation was the most influential indirect influence on suicidal ideation. Conclusion: To sum up the above results, if we promote the researched variables of self-esteem, family cohesion, social activity, individual coping and social support in addition to developing and utilizing an efficient customized suicidal prevention nursing intervention program thereby reducing depression and social isolation, suicidal ideation of elderly men living alone would be prevented.