• Title/Summary/Keyword: build-up effect

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Spatio-temporal Expression and Regulation of Dermatopontin in the Early Pregnant Mouse Uterus

  • Kim, Hyun Sook;Cheon, Yong-Pil
    • Molecules and Cells
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    • v.22 no.3
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    • pp.262-268
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    • 2006
  • During endometrial differentiation the extracellular matrix (ECM) changes dramatically to prepare for implantation of the embryo. However, the genes regulating the ECM build-up in the uterine endometrium during early pregnancy are not well known. Using the PCR-select cDNA subtraction method, dermatopontin was identified in the uterus of a pregnant mouse on day 4 of gestation. Dermatopontin mRNA increased dramatically on day 3, and was at its highest level at the time of implantation. Administration of RU 486 significantly inhibited mRNA expression by day 4 of gestation, but ICI 182,780 did not. Progesterone markedly induced dermatopontin expression in ovariectomized uteri within 4 h of administration, whereas estrogen had little effect. In silico analysis revealed progesterone receptor binding sites in the dermatopontin promoter region. Decidualization did not induce expression of dermatopontin; instead dermatopontin mRNA became strongly localized at the interimplantation site. In situ hybridization revealed that expression gradually decreased in the luminal epithelial cells as pregnancy progressed, whereas it increased in the stromal cells. The pattern of localization and the changes of intensity of dermatopontin mRNA coincided with those of collagen. Collectively, these results strongly suggest that dermatopontin expression is steroid-dependent. They also suggest that, at the time of implantation, dermatopontin expression is primarily regulated spatio-temporally by progesterone via progesterone receptors, and is modulated by the decidual response during implantation. Dermatopontin may be one of the regulators used to remodel the uterine ECM for pregnancy.

A Research on the Effect of Foreign Passengers' Satisfaction on Specialized Cabin Services on Long Haul Flight to Their Loyalty through Airline's Brand Asset (장거리노선 기내특화서비스에 대한 외국인 승객의 만족도가 항공사의 브랜드 자산을 매개로 하여 고객충성도에 미치는 영향에 대한 연구)

  • Kim, Kwang Il;Gwon, Eun Hyeong;Kim, Kee Woong;Park, Sung Sik
    • Journal of the Korean Society for Aviation and Aeronautics
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    • v.21 no.3
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    • pp.65-77
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    • 2013
  • A high brand reputation of a airline means the airline is preferred by passengers because of its unique services being even better than others. This is why airline's specialized services are important in that those services would create a new brand value and build up the airline's brand image, being enable to have competitive advantage over other airlines, to provide satisfied services, to have a mutual trust between passengers and the airline and to create customer's loyalty. A-Airline have been trying to give passengers a joy of flight by providing its customized and specialized cabin services out of airlnes' stereo-typed services.Therefore this paper will find out how their satisfaction of the cabin services have a positive impact on customer loyalty through brand image, brand reputation, brand identity and brand attraction. Those services would not only contribute to upgrade A-airline's corporate image but show the way to which the cabin service is heading also.

Clustering and traveling waves in the Monte Carlo criticality simulation of decoupled and confined media

  • Dumonteil, Eric;Bruna, Giovanni;Malvagi, Fausto;Onillon, Anthony;Richet, Yann
    • Nuclear Engineering and Technology
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    • v.49 no.6
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    • pp.1157-1164
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    • 2017
  • The Monte Carlo criticality simulation of decoupled systems, as for instance in large reactor cores, has been a challenging issue for a long time. In particular, due to limited computer time resources, the number of neutrons simulated per generation is still many order of magnitudes below realistic statistics, even during the start-up phases of reactors. This limited number of neutrons triggers a strong clustering effect of the neutron population that affects Monte Carlo tallies. Below a certain threshold, not only is the variance affected but also the estimation of the eigenvectors. In this paper we will build a time-dependent diffusion equation that takes into account both spatial correlations and population control (fixed number of neutrons along generations). We will show that its solution obeys a traveling wave dynamic, and we will discuss the mechanism that explains this biasing of local tallies whenever leakage boundary conditions are applied to the system.

Effect of Primer Coating Condition and Gap Clearance in $CO_2$ Laser Welding of Primer-coated Steel for Shipbuilding (조선용 프라이머 코팅강판의 $CO_2$ 레이저 용접에 있어서 프라이머 코팅 조건과 갭(Gap) 간극의 영향)

  • 길병래;장지연;김종도
    • Journal of Advanced Marine Engineering and Technology
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    • v.28 no.1
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    • pp.109-115
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    • 2004
  • The spatter and porosity could be occurred during$CO_2$CW laser welding of Primer- coated steel for shipbuilding. This study has suggested an alternative idea by examining of weld-defect formation mechanism. The primer-coated plate induced the spatter humping bead and porosity and these are main part of the welding defect. attributed to the powerful vaporizing pressure of primer attached on the base metal The zinc of Primer has a boiling point that is the lower temperature than melting point of steel zinc vapor will build up at the interface between the two sheets and this tends to deteriorate the quality of the weld by ejecting weld material from lap position or leaving porosity. Therefore introducing a small gap clearance in the lap position. the zinc vapor could escape through it and sound weld beads can be acquired. In conclusion, we suggested the occurred and prevented mechanism of weld defects with searching the factor.

CAE-based DFSS Study for Road Noise Reduction (로드 노이즈 개선을 위한 전산응용해석 기반 DFSS 연구)

  • Kwon, Woo-Sung;Yoo, Bong-Jun;Kim, Byoung-Hoon;Kim, In-Dong
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.21 no.7
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    • pp.674-681
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    • 2011
  • In the early phase of vehicle development, CAE is conducted as tool for vehicle performance assessment. To maintain acceptable road noise performance, solution for reduced vehicle sensitivity is required. Chassis interface dynamic stiffness characteristics are key component to isolating vibration and noise of road from the vehicle interior. This research provide how to set up the optimized dynamic characteristics under noise effect through DFSS study. CAE-based DOE is performed to build prediction math model, CMS process involves DOE to achieve very fast run times while giving results very comparable. Minimized 95th percentile of performance distribution is applied to minimize vehicle sensitivity and road noise levels variation during the optimization process. Finally, the results of optimization were reviewed for performance and robustness.

Dyeing Properties of Nylon 6 and Polyester Fabrics with Vat Dyes - Effect of Composition of Reducing Agent and Alkali on Color Change - (배트염료에 의한 나일론과 폴리에스테르 섬유의 염색성 - 색상 변화에 미치는 하이드로슬파이트와 NaOH의 영향 -)

  • ;;;Tomiji Wakida
    • Textile Coloration and Finishing
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    • v.14 no.5
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    • pp.284-293
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    • 2002
  • Nylon 6 and polyester taffeta fabrics are dyed in aqueous medium with vat dyes such as Indanthren Red FBB, Mikethren Blue ACE and Mikethren Blue HR varying the compositions of sodium hydrosulfite and NaOH. Also nylon UMF nonwoven and polyester UMF knitted fabrics are dyed with metal complex and disperse dyes as a reference, and the wash and rubbing fastnesses for these dyes are investigated. In vat dyeing of polyester and nylon taffeta, an optimum composition of sodium hydrosulfite/NaOH is existed at a range of 1∼2wt%/0.2wt%. A good build-up property for Mikethren Blue ACE on nylon 6 UMF nonwoven fabric is shown at high temperature. Vat dyeing of polyester with Mikethren Blue Ace shows a good color shade in a higher temperature, while dyeing with Mitsui Blue HR shows low temperatures. Vat dyes In dyeing of both nylon 6 UMF nonwoven and polyester UMF knitted fabrics have a better wash fastnesses compared with metal complex or disperse dyes.

Optical Model of a Human Eye's Crystalline Lens Based on a Three-layer Liquid Lens

  • Kong, Meimei;Chen, Xin;Yuan, Yang;Zhao, Rui;Chen, Tao;Liang, Zhongcheng
    • Current Optics and Photonics
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    • v.3 no.2
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    • pp.177-180
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    • 2019
  • Based on liquid-lens technology and our previous findings on the optical model of the Chinese eye, the liquid lens is applied in the research of the crystalline-lens optical model. Theoretical models of three-layer liquid lenses are built with COMSOL software, and the effect of voltage on the shape of the interface between two liquids is analyzed. By polynomial fitting, different equations describing the interface shape are set up under different voltages. Finally, the optical system of the human eye with a three-layer liquid lens is built and analyzed with Zemax optical design software, and moreover the optical system models of emmetropia, myopia, and hyperopia are presented. This method to build a model of the human eye with a variable-focus liquid lens can provide a novel idea for more practical human-eye models for clinical regulation and control in the future.

Total pressure dependence of YBCO films in MOD method (MOD 공정에 의해 제조된 YBCO 박막의 압력 의존성)

  • Yoo, Jai-Moo;Chung, Kook-Chae;Ko, Jae-Woong;Kim, Young-Kuk;Wang, Xiao Lin;Dou, Shi Xue
    • Progress in Superconductivity and Cryogenics
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    • v.8 no.1
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    • pp.5-8
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    • 2006
  • The growth properties of MOD-YBCO films were investigated. To enhance the growth rate of YBCO layer and inhibit the build-up of HF gas during the annealing process in TFA-MOD for YBCO coated conductors the method of low pressure annealing was employed. Total pressure was changed from 700Torr to 1Torr and its effect on growth of YBCO films was compared with atmospheric one. The lower Pressure was effective to control of the pore size in MOD method . Surface morphology of YBCO films processed at low total pres sure was rough and composed of random YBCO (103) grains. But large pores, usually observed at atmospheric process in MOD disappeared and also the number of pores was reduced at low pressure annealing. Also discussed ate the effects of Fluorine-free Y and Cu precursor solution on the development of microstructure. Dense surface me phology and with less and small pores can be provided through controlling Fluorine content.

Beyond halo mass: the role of vorticity-rich filaments in quenching galaxy mass assembly

  • Song, Hyunmi;Laigle, Clotilde;Hwang, Ho Seong;Devriendt, Julien;Dubois, Yohan;Kraljic, Katarina;Pichon, Christophe;Slyz, Adrianne;Smith, Rory
    • The Bulletin of The Korean Astronomical Society
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    • v.45 no.1
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    • pp.39.1-39.1
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    • 2020
  • We examine how the mass assembly of central galaxies depends on their location in the cosmic web. The HORIZON-AGN simulation is analysed at z~2 using the DISPERSE code to extract multi-scale cosmic filaments. We find that the dependency of galaxy properties on large-scale environment is mostly inherited from the (large-scale) environmental dependency of their host halo mass. When adopting a residual analysis that removes the host halo mass effect, we detect a direct and non-negligible influence of cosmic filaments. Proximity to filaments enhances the build-up of stellar mass, a result in agreement with previous studies. However, our multi-scale analysis also reveals that, at the edge of filaments, star formation is suppressed. In addition, we find clues for compaction of the stellar distribution at close proximity to filaments. We suggest that gas transfer from the outside to the inside of the haloes (where galaxies reside) becomes less efficient closer to filaments, due to high angular momentum supply at the vorticity-rich edge of filaments. This quenching mechanism may partly explain the larger fraction of passive galaxies in filaments, as inferred from observations at lower redshifts.

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High Energy Photon Dosimetry by ESR Spectroscopy in Radiotherapy (ESR Spectroscopy에 의한 치료용 고에너지 광자선의 선량측정)

  • Chu, Sung-Sil
    • Progress in Medical Physics
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    • v.1 no.1
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    • pp.31-42
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    • 1990
  • The finding of long lived free radicals produced by ionizing radiation in organic crystals and the quantification of this effect by electron spin resonance(ESR) spactroscopy has proven excellent dosimetric applicability. The tissue equivalent alanine dosimeter also appear appropriate for radiation therapy level dosimetry. The dose measurement was performed in a Rando phantom using high energy photons as produced by high energy medical linear accelerator and cobalt-60 teletherapy unit. The absorbed dose range of the ESR/alanine dosimetry system could be extended down to 0.1 Gy. The response of the alanine dosimeters was determined for photons at different therapeutic dose levels from less than 0.1 Gy to 100 Gy and the depth dose measurements were carried out for photon energies of 1.25MeV, 6 and 10 MV with alanine dosimeters in Rando phantom. Comparisons between ESR/alanine in a Rando phantom and ion chamber in a water phantom were made performing depth dose measurements to examine the agreement of both methods under field conditions.

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