• The Journal of Internal Korean Medicine
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• v.24 no.4_2
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• pp.1014-1022
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• 2003

Aphasia is speech disorder caused by injuries on the speech nerve center. It usually occur due to a disease in the right cerebral cortex and is divided into the various aphasia such as Global aphasia, Broca's aphasia, Wernicke's aphasia, conduction aphasia, Anomic aphasia, etc. Jihwangumja is used the cerebral infarction with Aphasia due to deficiency syndrome of kidneys. The purpose of this study is to examine the efficacy of oriental treatment for cerebral infarction with aphasia by Jihwangumsa. In the hospital, the patient showed the symptoms of mental disorder, Rt. hemiparesis G3/G4, aphasia, chest discomfort, obstipation, frequent urination, etc. The case showed that acute infarction on Lt. fronto-temporo-parietal lobe in Brain-CT. We identified the patient's clinical conditions and treated accordingly. As a result of treatment, symptoms were markedly improved and he was discharged. Further elaboration of oriental diagnostic classification could possibly lead to the fundamental treatment.

• Speech Sciences
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• v.9 no.3
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• pp.113-120
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• 2002

The purpose of this study was to determine the effects of group therapy on the language performance of aphasic patients. Four aphasic subjects participated in group therapy. Their aphasic types were TCMA (transcortical motor aphasia), conduction, anomie, and Broca's aphasia. The focus of the therapy was to stimulate cooperative learning skills. For this purpose, categorization tasks, semantic association tasks, convergent thinking, and divergent thinking tasks were employed. The results showed that all of the aphasic subjects demonstrated some improvement in writing ability, categorization ability, and speaking ability in sentences.

• Korean Journal of Cognitive Science
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• v.9 no.1
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• pp.41-46
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• 1998

The argument-structure distributions of predicates in the speech of two roca-type aphasic patients and one Conduction-type patient are compared with both matched controls and each other on the basis of narrative production data. Whereas English-speaking agrammatics have been reported to have difficulties producing noncopular unaccusative predicates (Kegl 1995) Korean-speaking agrammatics are found not to have particular difficulties with unaccusative predicates. On the assumption that agrammatics lack specific syntactic knowledge for the processing of displaced arguments from their lexically specified positions. it is proposed that unaccusatives in Korean do not involve the displacement of arguments for Case-theoretic reasons or involve a vacuous movement. if any.

• Korean Journal of Cognitive Science
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• v.13 no.2
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• pp.15-23
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• 2002

This paper reports an experiment on Broca's aphasics' comprehension of a class of English constructions involving empty categories. Based on Grodzinsky's (1986) account of chance-level performance of agrammatic understanding of movement constructions and their thematic role assignments. I show that Grodzinsky's notion of invisible empty categories can be further extended to include pronomical anaphors (PRO's) in Chomsky's (1981) sense and that the asymmetry in their poor comprehension of subject- and object-control constructions can be explained by the heuristic mechanism of the default thematic role assignment rule. eventually supporting Grodzinsky's claim that empty categories are not visible In agrammatic's syntactic representation.

• Journal of Korean Neurosurgical Society
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• v.59 no.3
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• pp.306-309
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• 2016

Using diffusion tensor tractography (DTT), we demonstrated injury of the arcuate fasciculus (AF) in the nondominant hemisphere in two patients who showed subfalcine herniation after intracerebral hemorrhage (ICH) in the dominant hemisphere. Two patients (patient 1 and patient 2) with ICH and six age-matched control patients who have ICH on the left corona radiata and basal ganglia without subfalcine herniation were recruited for this study. DTT was performed at one month after onset in patient 1 and patient 2. AFs of both hemispheres in both patients were disrupted between Wernicke's and Broca's areas. The fractional anisotropy value and tract numbers of the right AFs in both patients were found to be more than two standard deviations lower than those of control patients. In contrast, the apparent diffusion coefficient value was more than two standard deviations higher than those of control patients. Using the configuration and parameters of DTT, we confirmed injury of the AF in the nondominant hemisphere in two patients with subfalcine herniation following ICH in the dominant hemisphere. Therefore, DTT would be a useful tool for detection of underlying injury of the AF in the nondominant hemisphere in patients with subfalcine herniation.

• Dementia and Neurocognitive Disorders
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• v.17 no.3
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• pp.110-119
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• 2018

Background and Purpose: To analyze $^{18}F-THK5351$ positron emission tomography (PET) scans of patients with clinically diagnosed nonfluent/agrammatic variant primary progressive aphasia (navPPA). Methods: Thirty-one participants, including those with Alzheimer's disease (AD, n=13), navPPA (n=3), and those with normal control (NC, n=15) who completed 3 Tesla magnetic resonance imaging, $^{18}F-THK5351$ PET scans, and detailed neuropsychological tests, were included. Voxel-based and region of interest (ROI)-based analyses were performed to evaluate retention of $^{18}F-THK5351$ in navPPA patients. Results: In ROI-based analysis, patients with navPPA had higher levels of THK retention in the Broca's area, bilateral inferior frontal lobes, bilateral precentral gyri, and bilateral basal ganglia. Patients with navPPA showed higher levels of THK retention in bilateral frontal lobes (mainly left side) compared than NC in voxel-wise analysis. Conclusions: In our study, THK retention in navPPA patients was mainly distributed at the frontal region which was well correlated with functional-radiological distribution of navPPA. Our results suggest that tau PET imaging could be a supportive tool for diagnosis of navPPA in combination with a clinical history.

• Speech Sciences
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• v.11 no.4
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• pp.151-161
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• 2004

The characteristics of generative naming ability between fluent aphasiacs and non-fluent aphasics were investigated for 10 fluent aphasics (6 Wernicke's and 4 conduction type) and 10 non-fluent aphasics (6 Broca's and 4 transcortical motor type). Subjects were given 2 types of generative naming task and asked to generate lists of words to categorical ('animal', 'things at a supermarket') and phonetic ('ㄱ', 'ㅇ', 'ㅅ') cues. The total numbers of correct and incorrect response and error type ratios were calculated. The results of the present study were as follows: (1) Fluent aphasics had higher generative naming scores than non-fluent aphasics. (2) A remarkable dissociation between performance on categorical and phonetic cue in both aphasic groups was observed. Both aphasic groups produced a large number of responses in the categorical cue. (3) There was no significant group-difference in the error type. (4) Any correlation between generative naming and confrontation naming in K - WAB was not found.

• The Journal of the Acoustical Society of Korea
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• v.35 no.4
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• pp.319-329
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• 2016

The present study was to test if breathing training in melodic intonation therapy (MIT) ameliorated the articulation intelligibility of Broca's aphasics or not. The experimental group did breathing training (2 stages) that preceded the MIT. In order to evaluate the efficacy of the MIT intervention, the VOT (Voice Onset Time), the TD (Total Delay), the voice sound intensity and the expiratory volume of the subjects, closely associated with articulation intelligibility were measured before and after the intervention. It was shown that, in the experimental group after the MIT intervention, the VOT and TD were increased on bilabial/p/, alveolar consonant /t/, and soft palatal /k/(p < 0.05), but no significant differences were found on affricate /c/ and fricative /s/(p > 0.05). In the control group, no significant increases in the VOT and TD were observed on all articulation points(p > 0.05). The voice sound intensity which influences the verbal articulation increased in the experimental group after the intervention(p < 0.05), whereas no significant changes were observed in the control group. In conclusion, the breathing training in the MIT was found to result in improving the articulation intelligibility of Broca's aphasiacs.

• Journal of Music and Human Behavior
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• v.2 no.2
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• pp.57-67
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• 2005

Most of stroke patients have not only physical difficulty but speech and neurological disorder because of hemiplegia and such unexpected changes cause psychologic disadaptability and absent-mindedness. Particularly, lowering of physical ability can lead to serious emotional problem from failure or frustration in daily life. Generally, treatment of patient with stroke put emphasis on physical rehabilitation but actually this patient had considerable speech disorder such as aphasia or articulation disorder. Moreover, failing of recognition function, mental disorder as hypochondria, and even visual and auditory disorder are represented. So it is effective to integrate verbal remediation and other treatments in medical care environment. In particular, patients with language disorder very often wither psychologically therefore it is efficient to use of music therapy that gives opulent emotion to aphasia patients. And primarily to investigate the effects of 10 sessions treatments; change in spoken total number of syllables, to confirm their own value by success of given task and reassure about themselves ability. All of 10 sessions stages were scored by MIT manual and its improvement were measured, that is, accomplishment was analyzed within each level in order to prove detail change of spoken total number of syllables. The result of this program organized from 2 syllables to 4 syllables is summarized as follows. Subject A completed in preliminary stage Level I, in 2 syllables case advanced to Level III in fifth session and to Level IV in seventh session, in 3 syllables case advanced to Level III in seventh session and to Level IV in ninth session, and in 4 syllables case showed 8% low success rate in first session but after repeated practice increased considerably in sixth session and in advanced to Level III in eighth session to Level IV in tenth session. Subject B also completed in preliminary stage Level I, in 2 syllables case advanced to Level III in forth session and to Level IV in sixth session, in 3 syllables case advanced to Level III in fifth session and to Level IV in seventh session, and in 4 syllables case showed 10% low success rate in first session and increased considerably in fifth session and in advanced to Level III in seventh session but could not reach to Level IV until tenth session. As a result, it was shown that music therapy using MIT was not statistically meaningful but improved spoken total number of syllables and success rate of task had improved as a whole. Therefore, music intervention using MIT it has positive affect on verbal ability of patients with Broca's Aphasia and their language rehabilitation.