• Structural Monitoring and Maintenance
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• v.9 no.4
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• pp.305-321
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• 2022

Bridge structural health monitoring with the aim of continuously assessing structural safety and reliability represents a topic of major importance for worldwide infrastructure managers. In the last two decades, due to their potential economic and operational advantages, drive-by approaches experienced growing consideration from researcher and engineers. This work addresses two technical topics regarding indirect frequency estimation methods: bridge and vehicle dynamics overlapping, and bridge expansion joints impact. The experimental campaign was conducted on a mixed multi-span bridge located in Lombardy using a Ford Galaxy instrumented with a mesh of wireless accelerometers. The onboard time series were acquired for a number of 10 passages over the bridge,performed at a travelling speed of 30 km/h, with no limitations imposed to traffic. Exploiting an ad-hoc sensors positioning, pitch vehicle motion was compensated, allowing to estimate the first two bridge bending frequencies from PSD functions; moreover, the herein adopted approach proved to be insensitive to joints disturbance. Conclusively, a sensitivity study has been conducted to trace the relationship between estimation accuracy and number of trips considered in the analysis. Promising results were found, pointing out a clear positive correlation especially for the first bending frequency.

• Journal of Institute of Control, Robotics and Systems
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• v.10 no.12
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• pp.1164-1171
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• 2004

A new multi-scale simulation model is proposed to analyze heart mechanics. Electrophysiology of a cardiac cell is numerically approximated using the previous model of human ventricular myocyte. The ion transports across cell membrane initiated by action potential induce an excitation-contraction mechanism in the cell via cross bridge dynamics. Negroni and Lascano model (NL model) is employed to calculate the tension of cross bridge which is closely related to the ion dynamics in cytoplasm. To convert the tension on cell level into contraction force of cardiac muscle, we introduce a simple geometric model of ventricle with a thin-walled hemispheric shape. It is assumed that cardiac tissue is composed of a set of cardiac myocytes and its orientation on the hemispheric surface of ventricle remains constant everywhere in the domain. Application of Laplace law to the ventricle model enables us to determine the ventricular pressure that induces blood circulation in a body. A lumped parameter model with 7 compartments is utilized to describe the systemic circulation interacting with the cardiac cell mechanism via NL model and Laplace law. Numerical simulation shows that the ion transports in cell level eventually generate blood hemodynamics on system level via cross bridge dynamics and Laplace law. Computational results using the present multi-scale model are well compared with the existing ones. Especially it is shown that the typical characteristics of heart mechanics, such as pressure volume relation, stroke volume and ejection fraction, can be generated by the present multi-scale cardiovascular model, covering from cardiac cells to circulation system.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.48 no.1
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• pp.71-75
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• 2015

Nicotinic acetylcholine receptors (nAChRs) are essential for neurotransmission and important therapeutic targets of diseases related to neurotransmission. A recent experimental study identified three residues (Lys185, Asp187, and Ile188) of the ${\alpha}6$ nAChR subunit as determinants of ${\alpha}$-conotoxin BuIA selectivity, yet how these residues confer toxin selectivity remains unclear. In this study, we performed all-atom molecular dynamics simulations with two toxin-bound ${\alpha}4{\beta}2$ nAChR systems: the wild-type ${\alpha}4{\beta}2$ and one in which we replaced the three ${\alpha}4$ subunit residues with three ${\alpha}6$ subunit residues identified in an experimental study (Tyr185Lys, Thr187Asp, and Arg188Ile). After mutation, Asp199 lost the salt bridge formed with Arg188 in the wild type located around loop C. Then, the loop C conformation changed and became more flexible than that of the wild type. We also detected reduced space between the toxin and the binding site in the mutant simulation, resulting in increased binding affinity to the toxin. Therefore, we propose a new Asp199 mutation that breaks the salt bridge and may produce similar selectivity to that of the Arg188 mutation.

• Wind and Structures
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• v.5 no.2_3_4
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• pp.257-266
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• 2002

In the recent years flow around bridges are investigated using computer modeling. Selvam (1998), Selvam and Bosch (1999), Frandsen and McRobie (1999) used finite element procedures. Larsen and Walther (1997) used discrete vorticity procedure. The aeroelastic instability is a major criterion to be checked for long span bridges. If the wind speed experienced by a bridge is greater than the critical wind speed for flutter, then the bridge fails due to aeroelastic instability. Larsen and Walther (1997) computed the critical velocity for flutter using discrete vortex method similar to wind tunnel procedures. In this work, the critical velocity for flutter will be calculated directly (free oscillation procedure) similar to the approaches reported by Selvam et al. (1998). It is expected that the computational time required to compute the critical velocity using this approach may be much shorter than the traditional approach. The computed critical flutter velocity of 69 m/s is in reasonable comparison with wind tunnel measurement. The no flutter and flutter conditions are illustrated using the bridge response in time.

• Proceedings of the Earthquake Engineering Society of Korea Conference
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• 2001.04a
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• pp.353-360
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• 2001

An analysis procedure of 2-dimensional bridge dynamics has been developed by using force-deformation model, which simulates the pier motion under biaxial bending due to the bi-directional input seismic excitations. A three-dimensional mechanical model is utilized, which can consider the other major phenomena such as pounding, rotation of the superstructure, abutment stiffness degradation, and motions of the foundation motions. The bi-directional dynamic behaviors of the bridge are then examined by investigating the relative displacements of each oscillator to the ground. It is found that the nonlinearity of the pier due to biaxial bending affects the pier motions, but the global bridge behaviors are greatly governed by the pounding phenomena and stiffness degradation of the abutment-backfill system. Especially, the relative displacement of the abutment system (A2) with movable supports to the ground is increased about 30% due to the abutment stiffness degradation.

• Wind and Structures
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• v.18 no.3
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• pp.215-233
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• 2014

This paper presents a method to extract flutter derivatives of bridge decks based on a combination of the computational fluid dynamics (CFD), system simulations and system identifications. The incompressible solver adopts an Arbitrary Lagrangian-Eulerian (ALE) formulation with the finite volume discretization in space. The imposed sectional motion in heaving or pitching relies on exponential time series as input, with aerodynamic forces time histories acting on the section evaluated as output. System identifications are carried out to fit coefficients of the inputs and outputs of ARMA models, as to establish discrete-time aerodynamic models. System simulations of the established models are then performed as to obtain the lift and moment exerting on the sections to a sinusoidal displacement. It follows that flutter derivatives are identified. The present approaches are applied to a hexagon thin plate and a real bridge deck. The results are compared to the Theodorsen closed-form solution and those from wind tunnel tests. Satisfactory agreements are observed.

• Proceedings of the Earthquake Engineering Society of Korea Conference
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• 2001.09a
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• pp.295-301
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• 2001

For the seismic analysis of typical roadway bridges provisions are given in most codes for analysis models, which describes however only fundamental modelling methods according to the basic theories of structural dynamics. In practice even conventional non-seismic analysis models, separate super- and substructure models, are applied, which are not adequate because of neglecting connection elements. In this study three typical roadway bridges, a Steel box bridge, a PC beam bridge and a PC box bridge are selected and simple models integrating super- and substructure as well as connection elements are given. The simple models are composed with frame elements with lumped masses representing stiffness and mass characteristics of the selected bridges. To check the properness of the simple models, analysis results with the simple models are compared with those obtained with detailed models in view of bridge failure mechanisms. It is proved that the simple models can be used in the preliminary design phase fur the determination of failure mechanisms of typical roadway bridges.

• Proceedings of the KIPE Conference
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• 1997.07a
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• pp.101-110
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• 1997

The circuit effects due to the transformer primary side series equivalent inductance in the Zero Voltage Switching Pulse Width Modulated Half Bridge DC/DC Converter and its impact on the effective duty are analyzed. The steady state equations and the small signal model of the converter are derived incorporating the effects of the complementary control and the utilization of transformer primary side series equivalent inductance. The open plant dynamics are analyzed on the basis of the model derived. The model predictions are confirmed by experimental measurements.

• Wind and Structures
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• v.30 no.1
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• pp.55-67
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• 2020

Wind tunnel test is one of the most important means to study the flutter performance of bridges, but there are blockage effects in flutter test due to the size limitation of the wind tunnel. On the other hand, the size of computational domain can be defined by users in the numerical simulation. This paper presents a study on blockage effects of a simplified box girder by computation fluid dynamics (CFD) simulation, the blockage effects on the aerodynamic characteristics and flutter performance of a long-span suspension bridge are studied. The results show that the aerodynamic coefficients and the absolute value of mean pressure coefficient increase with the increase of the blockage ratio. And the aerodynamic coefficients can be corrected by the mean wind speed in the plane of leading edge of model. At each angle of attack, the critical flutter wind speed decreases as the blockage ratio increases, but the difference is that bending-torsion coupled flutter and torsional flutter occur at lower and larger angles of attack respectively. Finally, the correction formula of critical wind speed at 0° angle of attack is given, which can provide reference for wind resistance design of streamlined box girders in practical engineering.

• Wind and Structures
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• v.28 no.2
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• pp.99-110
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• 2019

Vortex-Induced-Vibration (VIV) is one kind of the wind-induced vibrations, which may occur in the construction and operation period of bridges. This phenomenon can bring negative effects to the traffic safety or can cause bridge fatigue damage and should be eliminated or controlled within safe amplitudes.In the current VIV studies, one available mitigation countermeasure, the horizontal flow-isolating plate, shows satisfactory performance particularly in PI shaped bridge deck type. Details of the wind tunnel test are firstly presented to give an overall description of this appendage and its control effect. Then, the computational-fluid-dynamics(CFD) method is introduced to investigate the control mechanism, using two-dimensional Large-Eddy-Simulation to reproduce the VIV process. The Reynolds number of the cases involved in this paper ranges from $1{\times}10^5$ to $3{\times}10^5$, using the width of bridge deck as reference length. A field-filter technique and detailed analysis on wall pressure are used to give an intuitive demonstration of the changes brought by the horizontal flow-isolating plate. Results show that this aerodynamic appendage is equally effective in suppressing vertical and torsional VIV, indicating inspiring application prospect in similar PI shaped bridge decks.