• Annals of Clinical Neurophysiology
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• v.14 no.1
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• pp.20-24
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• 2012

Background: Migraine patients can be sensitive to external or internal stimuli, such as light, noise, or hormonal changes. Using transcranial Doppler ultrasonography (TCD) with breath-holding method, we evaluated the changes of cerebrovascular reactivity (CVR) to hypercapnia in women with migraine without aura between fasting and postprandial period. Methods: Twelve women with migraine without aura and the same number of age and sex-matched healthy controls with no significant history of headache participated in this study. Using TCD examinations, we studied mean flow velocity in middle cerebral artery with better temporal window. Each subject was examined consecutively before and after a standard meal, together with serum glucose level and blood pressure. CVR was evaluated with breath-holding index (BHI). Results: Postprandial-BHI (mean+SD) was significantly higher than fasting-BHI (mean+SD) in patients group but not in controls (in patient group; postprandial-BHI=1.38, fasting-BHI=1.08, in control group; postprandial-BHI=1.25, fasting-BHI=1.18, P=0.021 and 0.239, respectively). After meal, serum glucose level was significantly enhanced but blood pressure was not in both groups. Serum glucose level of patients showed a tendency of mild positive correlation with BHIs (${\gamma}$=0.448, P=0.032). Conclusions: Although exact mechanisms are unclear, cerebrovascular reactivity of some women with migraine without aura may be influenced by prandial state.

• Radiation Oncology Journal
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• v.37 no.4
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• pp.254-258
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• 2019

Purpose: Deep inspiration breath hold (DIBH) is a well-established technique that enables efficient cardiac sparing in patients with left-sided breast cancer. The aim of the current study was to determine if DIBH is effective for reducing radiation exposure of of liver and other organs at risk in right breast radiotherapy (RT). Materials and Methods: Twenty patients with right-sided breast cancer were enrolled in this study. Three-dimensional conformal RT plans were generated for each patient, with two different computed tomography scans of free breathing (FB) and DIBH. Nodes were contoured according to the Radiation Therapy Oncology Group contouring guidelines. Dose-volume histograms for the target volume coverage and organs at risk were evaluated and analyzed. Results: DIBH plans showed significant reduction in mean liver dose (5.59 ± 2.07 Gy vs. 2.54 ± 1.40 Gy; p = 0.0003), V_20Gy (148.38 ± 73.05 vs. 64.19 ± 51.07 mL; p = 0.0003) and V_10Gy (195.34 ± 93.57 vs. 89.81 ± 57.28 mL; p = 0.0003) volumes compared with FB plans. Right lung doses were also significantly reduced in DIBH plans. Heart and left lung doses showed small but statistically significant improvement with application of the DIBH technique. Conclusion: We report that the use of DIBH for right-sided breast cancer significantly reduces the radiation doses to the liver, lungs, and heart.

• The Journal of Internal Korean Medicine
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• v.11 no.1
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• pp.53-60
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• 1990

The results are as follows through the investigation of literature. 1. The cause of shortness of breath due to fluid retention is abnormal rising of water-evil and it srepregentative symptom are as follows'Cough or dyspnea, shortness of breath-sleeplessness, rapid respiration accused by having rest, edemd on the body and leg' 2. Dyspnea caused by fire-evil is It repregentative symptom are 'getting better or getting worse, reducing by eating rapid respiration accused by eating If having rest the ditalenergy (gui) is made a peace At moving, the vital energy is abrupt or irregalar and acused rapid respiration' 3. From the point of view, the rapid respiration accused by heart usually bring about imperfect left heart Its repregentetive symptom are cyspnea, acute dyspnea at night, bronchial wheezing edema on the leg, and the thing which bring about at moving is mildcase but what bring about at rest is severe case 4. We have known that the symptom of shortness of breath due to fluid retention are similiar to cardiac rapid respiration, and the symptom of dyspnea acused by fire-evil alike 'dyspnea at moving' acused at mild case of cardiac rapid respiration.'

• Journal of Environmental Science International
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• v.4 no.3
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• pp.277-284
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• 1995

There has been an increased awareness of the need to confirm the chloroform exposure associated with using chlorinated household water. Ten of a 30-minute tub bath were normally taken by two volunteers in a bathroom of an apartment. Chloroform concentrations were measured in bathing water and bathroom air, and exhaled breath of the subjects prior to and after bathing. Bathing using chlorinated tap water resulted in a chloroform exposure and caused a body burden. Based on the difference of chloroform concentrations between breath samples collected prior to and after bathing, the chloroform body burden from a 30-minute bath was estimated to be about 8 to 26 folds higher than that prior to the bath. The mean water and bathroom air chloroform concentrations measured to evaluate the body burden were $9.4\mu\textrm{g}/l$ and TEX>$14.9\mu\textrm{g}/m^3$, respectively. The chloroform level of the bathroom air was 각 to 130 times higher than that of the living-room air. The relationship between the bathroom air and the corresponding breath chloroform concentrations were significant with p=0.03 and $R^2=0.47$.

• Journal of Environmental Science International
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• v.4 no.3
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• pp.125-125
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• 1995

There has been an increased awareness of the need to confirm the chloroform exposure associated with using chlorinated household water. Ten of a 30-minute tub bath were normally taken by two volunteers in a bathroom of an apartment. Chloroform concentrations were measured in bathing water and bathroom air, and exhaled breath of the subjects prior to and after bathing. Bathing using chlorinated tap water resulted in a chloroform exposure and caused a body burden. Based on the difference of chloroform concentrations between breath samples collected prior to and after bathing, the chloroform body burden from a 30-minute bath was estimated to be about 8 to 26 folds higher than that prior to the bath. The mean water and bathroom air chloroform concentrations measured to evaluate the body burden were $9.4\mu\textrm{g}/l$ and TEX>$14.9\mu\textrm{g}/m^3$, respectively. The chloroform level of the bathroom air was 각 to 130 times higher than that of the living-room air. The relationship between the bathroom air and the corresponding breath chloroform concentrations were significant with p=0.03 and $R^2=0.47$.

• Korean Journal of Oriental Medicine
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• v.14 no.1
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• pp.73-83
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• 2008

Background : Kigong(氣功) is to develope a nature-therapy by controling and recovering Jinki(眞氣) and it has common features in Yangsaengbeob(養生法), Doinbeob(導引法) and Jeongkisin(精氣神), but it is rarely researched and applied in clinic examine. Objectives : it is compared and contrasted among Kukseondo(國仙道) Yeonjeongwon(硏精院), Seokmunhoheub(石門呼吸). Result : Kukseondo, Yeonjeongwon, Seokmunhoheub have the same point that beginners breath slowly, deeply and naturally. The breathing in each group becomes deeper gradually by mental and physical relaxation although each group has a different breathing method, and it is similar to Jogigyeol(調氣訣) in Dongeuibogam. Ywasik(臥式) is distinguished by the presence of sensation. The breathing in Kukseondo is Yidanhoheub(二段呼吸), the breathing in Yeonjeongwon is Yugi(留氣) and the breathing in Seokmunhoheub is that the ratio of inhaling and blowing are 6 to 4. The breathing in each group is deep and small, Ki also accumulates in the Below-abdomen between blowing and inhaling. This is confirmed by Sinjunapgi(腎主納氣) theory in Oriental-medicine. There is the breath, which is through skin, in Kigonghoheub(氣孔呼吸) of Samhabdanbeop(三合丹法) and Jolidanbeop(造理丹法) in Kukseondo, it is also in Gwiilbeop(歸一法) of Seokmunhoheub. In Kukseondo's case, the breathing is through skin mainly instead of a respiratory organ. In Seokmunhoheub's case, the circulation of Ki is through skin during breathing. In Oriental-medicine, this is called as Pyejupimo(肺主皮毛) which is connected with lung and skin. The breathing coincide with tension and relaxation of body while the breathing through skin and the absorption of Ki spread sensation over the whole body, but the breathing through skin is just a specific ability from a training.

• Korean Journal of Clinical Laboratory Science
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• v.39 no.3
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• pp.271-276
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• 2007

Helicobacter pylori (H. pylori) infection is common in korea and high incidence at gastric ulcer and duodenal ulcer. $^{14}C-urea$ breath test ($^{14}C-UBT$) is regarded as a highly reliable and non-invasive method for the diagnosis of H. pylori infection. The purpose of this study was to evaluate the diagnositc performance of a new and rapid $^{14}C-UBT$, which was equipped with Geiger-Muller counter and compared the results with those obtained by gastroduodenoscopic biopsies (GBx). One hundred sixty-eight patients (M : F = 118 : 50) underwent $^{14}C-UBT$, rapid urease test (CLO test), and GBx. The results of $^{14}C-UBT$ were classified as positive (>50 cpm), borderline (25$^{14}C-UBT$ or CLO test results with GBx as a glod standard. In the assessment of the presence of H. pylori infection, the $^{14}C-UBT$ global performance yielded positive predictive value, negative predictive value and accuracy of 93.3% and 83.3%, respectively. However, the CLO test had performance yielded positive predictive value, negative predictive value and accuracy of 76.9%, 50.0%, respectively. In this study $^{14}C-UBT$ is a highly accurate, simple and non-invasive method or the diagnosis of follow up H. pylori infection.

• Journal of dental hygiene science
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• v.20 no.3
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• pp.126-135
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• 2020

Background: The purpose of this study is to investigate the effects of entrance exam stress on oral health behaviors and subjective oral health status in female high school students. Methods: A self-reported questionnaire was administered to 216 female high school students in the Gwangju area. We performed an independent t-test, one-way analysis of variance (ANOVA), Pearson's correlation coefficient, and multiple regression analysis using the SPSS/WIN 21.0 program. Results: The average of the entrance exam stress was 2.73, and among the sub-areas, the tension for exam/poor stress was the highest with 3.21. As a result of analysis of general characteristics and subjective oral health status, oral mucosal disease was lower in family income level (p<0.05), bad breath was significantly higher with lower academic performance (p<0.001) and family income level (p<0.05). As a result of oral health behavior and subjective oral health status analysis, dental caries has more than 4 times of caries snacks (per week) (p<0.05), bad breath was found to be more perceived when the average number of daily brushing was 2 or less (p<0.01). Factors affecting subjective oral health status were that dental caries was a patients pressure stress (β=0.202); temporomandibular disorder (β=0.227), xerostomia (β=0.342), and oral mucosal disease (β=0.190) were insufficient spare time; bad breath was academic performance (lower) (β=0.231) and insufficient spare time (β=0.184). There was a statistically significant positive correlation between the subjective oral health status and the subarea of entrance exam stress, excluding future uncertainty stress. Conclusion: It is considered that oral health education should be conducted to prevent oral diseases for students with high parental pressure and insufficient spare time stress as well as finding practical ways to reduce entrance stress.

• The Journal of Korean Medicine
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• v.35 no.2
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• pp.12-18
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• 2014

Objectives: This was a retrospective case series about the clinical effect of integrated approach with behavior therapy for obstructive sleep apnea (OSA). Methods: Medical records of twelve patients with OSA who were treated with behavior modification including nasal breathing with oral appliances and sleep in lateral position, oral administration of herbal medicines and acupuncture treatment between January and September of 2013 were reviewed. Apnea-hypopnea index (AHI), day time sleepiness, apneas and hypopneas counts during sleep, risk indicator (RI), oxygen desaturation index, average saturation during sleep, lowest desaturation, lowest saturation, snoring events ratio and number of desaturations (%) were assessed before and after treatments with the ApneaLink device, which is a portable diagnostic apparatus for monitoring airflows of the patient's breath at home. Results: After an average 62.67 (SD 37.16) days of treatment, AHI (from 17.67, 12.79 to 8.75, 8.25, p=0.007), RI (from 22.00, 13.26 to 12.09, 8.03, p=0.004), oxygen desaturation index (from 17.33, 12.17 to 8.17, 7.86, p=0.005), and number of desaturations (from 7.00 times, 9.79 to 0.92 times, 1.39, p=0.044) showed significant improvement. Daytime sleepiness improved from 6.5 (3.2) to 3.8 (1.8) but there was no significant difference after treatment (p=0.17). No adverse events related to treatment were observed during participation in the treatment. Conclusion: From this case series, we found that behavior modification with herbal medication and acupuncture may be effective for improving sleep apnea without serious adverse events. Future randomized controlled trials with larger sample size will be necessary for concrete evidence on the benefit of this integrated treatment for OSA.

• Toxicological Research
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• v.26 no.4
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• pp.329-337
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• 2010

Inhaled inorganic dusts, such as coal, can cause inflammation and fibrosis in the lungs, known as pneumoconiosis. Diagnosis of pneumoconiosis depends on morphological changes by radiological findings and functional change by pulmonary function test (PFT). Unfortunately, current diagnostic findings are limited only to lung fibrosis, which is usually irreversibly progressive. Therefore, it is important that research on potential and prospective biomarkers for pneumoconiosis should be conducted prior to initiation of irreversible radiological or functional changes in the lungs. Analytical techniques using exhaled breath condensate (EBC) or exhaled gas are non-invasive methods for detection of various respiratory diseases. The objective of this study is to investigate the relationship between inflammatory biomarkers, such as EBC pH or fractional exhaled nitric oxide ($FE_{NO}$), and pneumoconiosis among 120 retired coal miners (41 controls and 79 pneumoconiosis patients). Levels of EBC pH and FENO did not show a statistically significant difference between the pneumoconiosis patient group and pneumoconiosis patients with small opacity classified by International Labor Organization (ILO) classification. The mean concentration of $FE_{NO}$ in the low percentage $FEV_1$ (< 80%) was lower than that in the high percentage (80% $\leq$) (p = 0.023). The mean concentration of $FE_{NO}$ in current smokers was lower than that in non smokers (never or past smokers) (p = 0.027). Although there was no statistical significance, the levels of $FE_{NO}$ in smokers tended to decrease, compared with non smokers, regardless of pneumoconiosis. In conclusion, there was no significant relationship between the level of EBC pH or $FE_{NO}$ and radiological findings or PFT. The effects between exhaled biomarkers and pneumoconiosis progression, such as decreasing PFT and exacerbation of radiological findings, should be monitored.