• Computers and Concrete
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• v.18 no.6
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• pp.1135-1151
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• 2016

For investigating the effect of the pre-existing joints on the initiation pattern of hydraulic fractures, the numerical simulation of circular holes under internal hydraulic pressure with a different pattern of the joint distributions are conducted by using a finite element code, FRANC2D. The pattern of hydraulic fracturing initiation are scrutinized with changing the values of the joint length, joint offset angle. The hydraulic pressures with 70% of the peak value of borehole wall breakout pressure are applied at the similar models. The simulation results suggest that the opening-mode fracture initiated from the joint tip and propagated toward the borehole for critical values of ligament angle and joint offset angle. At these critical values, the crack grow length is influenced by joint ligament length. When the ligament length is less than 3 times the borehole diameter the crack growth length increases monotonically with increasing joint length. The opening-mode fracture disappears at the joint tip as the ligament length increases.

• Biomolecules & Therapeutics
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• v.21 no.1
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• pp.1-9
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• 2013

Polyamines, putrescine, spermidine and spermine, are ubiquitous in living cells and are essential for eukaryotic cell growth. These polycations interact with negatively charged molecules such as DNA, RNA, acidic proteins and phospholipids and modulate various cellular functions including macromolecular synthesis. Dysregulation of the polyamine pathway leads to pathological conditions including cancer, inflammation, stroke, renal failure and diabetes. Increase in polyamines and polyamine synthesis enzymes is often associated with tumor growth, and urinary and plasma contents of polyamines and their metabolites have been investigated as diagnostic markers for cancers. Of these, diacetylated derivatives of spermidine and spermine are elevated in the urine of cancer patients and present potential markers for early detection. Enhanced catabolism of cellular polyamines by polyamine oxidases (PAO), spermine oxidase (SMO) or acetylpolyamine oxidase (AcPAO), increases cellular oxidative stress and generates hydrogen peroxide and a reactive toxic metabolite, acrolein, which covalently incorporates into lysine residues of cellular proteins. Levels of protein-conjuagated acrolein (PC-Acro) and polyamine oxidizing enzymes were increased in the locus of brain infarction and in plasma in a mouse model of stroke and also in the plasma of stroke patients. When the combined measurements of PC-Acro, interleukin 6 (IL-6), and C-reactive protein (CRP) were evaluated, even silent brain infarction (SBI) was detected with high sensitivity and specificity. Considering that there are no reliable biochemical markers for early stage of stroke, PC-Acro and PAOs present promising markers. Thus the polyamine metabolites in plasma or urine provide useful tools in early diagnosis of cancer and stroke.

• 한국가시화정보학회:학술대회논문집
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• 2004.12a
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• pp.125-134
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• 2004

The improvement of artificial respiration method has brought about the decrease in mortality of pulmonary diseases patients. Various respiratory curative methods, inclusive of HFOV (High Frequency Oscillatory Ventilation), have been developed for more effectual and less harmful management of acute respiratory failure. However, the mechanism of gas transfer and diffusion in a bronchiole has not yet been clarified in detail. As a first approach to the problem, we measured oscillatory flows in a Y-shaped micro-channels as bronchiole model by micro Particle Image Velocimetry(micro PIV). In order to establish the fundamental technique of PIV measurements on oscillatory air flow in a micro-channel, we used about 500-nm-diameter incense smoke particles, a diode laser, a high speed camera including an objective lens, and a HFOV, which is effective technique for medical care of pulmonary disease patients, especially, infants. The bronchiole model size is that parent tube is $500\{mu}m$ width and $500\{mu}m$ depth, and daughter tubes are $450\{mu}m$ width and $500\{mu}m$ depth. From this study made on the phenomenon of fluid in micro size bronchus branch of a lung, we succeeded to get time series velocity distribution in a micro scale bronchial mode. The experimental results of velocity distribution changing with time obtained by micro PIV can give fundamental knowledge on oscillatory airflow in micro-channel.

• Journal of Welding and Joining
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• v.25 no.3
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• pp.78-84
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• 2007

Laser Material Processing has been replaced the conventional machining systems - cutting, drilling, welding and surface modification and so on. Especially, LTH(Laser Transformation Hardening) process is one branch of the laser surface modification process. Conventionally, some techniques like a gas carburizing and nitriding as well as induction and torch heating have been used to harden the carbon steels. But these methods not only request post-machining resulted from a deformation but also have complex processing procedures. Besides, LTH process has some merits as : 1. It is easy to control the case depth because of output(laser power) adjustability. 2. It is able to harden the localized and complicated a.ea and minimize a deformation due to a unique property of a localized heat source. 3. An additional cooling medium is not required due to self quenching. 4. A prominent hardening results can be obtained. This study is related to the surface hardening of the rod-shaped carbon steel applied to the lathe based complex processing mechanism, a basic behavior of surface hardening, hardness distribution and structural characteristics in the hardened zone.

• Health Policy and Management
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• v.13 no.4
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• pp.115-130
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• 2003

Reperfusion delay in patients with acute myocardial infarction leads to increased morbidity and mortality. We sought to measure the rates of reperfusion delay and to identify factors associated with reperfusion delay after arrival to hospitals. We included 360 patients who had acute myocardial infarction with ST-elevation or left bundle branch block on electrocardiogram and received reperfusion therapy from the three participating academic medical centers from 1997 to 2000. Through retrospective chart review, we collected data about time to reperfusion therapy, patient and hospital factors potentially associated with reperfusion delay. Factors independently associated with reperfusion delay were determined by logistic regression analysis. Median door­to­needle time was 60.0 minutes, and median door­to­balloon time was 102.5 minutes. According to recommendation of the American College of Cardiology/American Heart Association Guidelines, 226 out of 264(85.6％) of thrombolytic patients and 43 out of 96(44.8％) percutaneous transluminal coronary angioplasty(PTCA) patients experienced reperfusion delay. The significant factors associated with delay were type of reperfusion therapy, patient factors including hypertension and delayed symptom onset to presentation(>4 hours), and hospital factors including nocturnal presentation(6pm∼8am), weekend, and an individual hospital. A significant proportion of patients experienced reperfusion delay. The identified predictors of reperfusion delay may help design a hospital system to reduce the delay in reperfusion therapy

• Journal of the Korean Society of Clothing and Textiles
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• v.31 no.8
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• pp.1180-1189
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• 2007

The purpose of this study is to search the level of localization strategy of imported brands in Korean Market, to investigate relationship between the brand characteristics and localization strategy, and to study the case about localization strategy of the brand selected according to the type of brand. The survey research was employed and for the data analysis, descriptive statistics, one-way ANOVA, and multiple-regression were used. For the case study, interview with the person who works in the each kind of company was used. The results of this study were as follows: Firstly, the level of localization strategy is found in order price, place, promotion and product. Secondly among the brand characteristics, type of brand, proportion of garments, price zone, launching time, number of shop are related with localization strategy, but turnover and number of the staff are not. Thirdly, license brand has the characteristics like as national brands and the differences between the branch and the agent is confidence and communication that are the basic elements of localization. This study can help national brands to refer the localization strategy and provide the understanding of localization strategy of imported brands in Korean fashion market.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.13 no.12
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• pp.6009-6027
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• 2019

Support vector machine (SVM) classifiers have been widely used for object detection. These methods usually locate the object by finding the region with maximal score in an image. With bag-of-features representation, the SVM score of an image region can be written as the sum of its inside feature-weights. As a result, the searching process can be executed efficiently by using strategies such as branch-and-bound. However, the feature-weight derived by optimizing region classification cannot really reveal the category knowledge of a feature-point, which could cause bad localization. In this paper, we represent a region in an image by a collection of local feature-points and determine the object by the region with the maximum posterior probability of belonging to the object class. Based on the Bayes' theorem and Naive-Bayes assumptions, the posterior probability is reformulated as the sum of feature-scores. The feature-score is manifested in the form of the logarithm of a probability ratio. Instead of estimating the numerator and denominator probabilities separately, we readily employ the density ratio estimation techniques directly, and overcome the above limitation. Experiments on a car dataset and PASCAL VOC 2007 dataset validated the effectiveness of our method compared to the baselines. In addition, the performance can be further improved by taking advantage of the recently developed deep convolutional neural network features.

• Journal of The Korean Astronomical Society
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• v.48 no.2
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• pp.93-104
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• 2015

WFIRST microlensing observations will return high-precision parallaxes, σ(π) . 0.3 µas, for the roughly 1 million stars with H < 14 in its 2.8 deg² field toward the Galactic bulge. Combined with its 40,000 epochs of high precision photometry (∼ 0.7 mmag at H_vega = 14 and ∼ 0.1 mmag at H = 8), this will yield a wealth of asteroseismic data of giant stars, primarily in the Galactic bulge but includindvvvvvg a substantial fraction of disk stars at all Galactocentric radii interior to the Sun. For brighter stars, the astrometric data will yield an external check on the radii derived from the two asteroseismic parameters, the large-frequency separation <∆ν_nl> and the frequency of maximum oscillation power ν_max, while for the fainter ones, it will enable a mass measurement from the single measurable asteroseismic parameter ν_max. Simulations based on Kepler data indicate that WFIRST will be capable of detecting oscillations in stars from slightly less luminous than the red clump to the tip of the red giant branch, yielding roughly 1 million detections.

• ETRI Journal
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• v.26 no.2
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• pp.101-111
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• 2004

This paper presents a near-optimum blind decision feedback equalizer (DFE) for the receivers of Advanced Television Systems Committee (ATSC) digital television. By adopting a modified trellis decoder (MTD) with a trace- back depth of 1 for the decision device in the DFE, we obtain a hardware-efficient, blind DFE approaching the performance of an optimum DFE which has no error propagation. In the MTD, the absolute distance is used rather than the squared Euclidean distance for the computation of the branch metrics. This results in a reduction of the computational complexity over the original trellis decoding scheme. Compared to the conventional slicer, the MTD shows an outstanding performance improvement in decision error probability and is comparable to the original trellis decoder using the Euclidean distance. Reducing error propagation by use of the MTD in the DFE leads to the improvement of convergence performance in terms of convergence speed and residual error. Simulation results show that the proposed blind DFE performs much better than the blind DFE with the slicer, and the difference is prominent at the trellis decoder following the blind DFE.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.13 no.5
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• pp.229-233
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• 2013

Mine detector of troops is different from other equipments. It is a base of a miner branch's combat, combat support and mission. But its notion is too obsucure and each troops' model and maker of it is so different and most of it is old type so there are a lot of malfunctions. Hence, I will define management of mine detector and figure out these days miner troops' mine detector situation. I will collect experts' opinions too. Through a discussion we could found improvement plan and develop it adequate for future operational environment. Proceeding all these courses and finally making it weaponize are the points of this writing.