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Does a High Ratio of Dietary Omega-6/Omega-3 Fatty Acids Increase the Risk of Helicobacter pylori Infection? A Case-Control Study

  • Masoumeh Khalighi Sikaroudi;Zohreh Ebrahimi;Melika Darzi;Zainab Shateri;Mehran Nouri;Mohsen Masoodi;Mahdi Hejazi;Farzad Shidfar
    • Clinical Nutrition Research
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    • v.13 no.3
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    • pp.176-185
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    • 2024
  • Helicobacter pylori infection is the cause of 90% of non-cardia gastric cancer. Several dietary elements have been identified as possible contributors to H. pylori infection and its advancement through various pathways. Based on the anti-inflammatory and anti-microbial effects of a diet low in omega-6 and high in omega-3 polyunsaturated fatty acids (PUFAs), this study aimed to assess the ratio of dietary omega-6 to omega-3 PUFAs and the risk of developing H. pylori. The present case-control study was conducted on 150 cases with H. pylori infection and 302 controls. The omega-6 to omega-3 ratio was calculated using food intake information sourced from a validated food frequency questionnaire. Physical activity and demographic data were collected through a related questionnaire. The association between the odds of H. pylori infection and the omega-6 to omega-3 ratio was evaluated using logistic regression models. A p value < 0.05 was considered statistically significant. The findings revealed that individuals in the third tertile had significantly higher odds of H. pylori (odds ratio [OR], 2.10; 95% confidence interval [CI], 1.30-3.40) in the crude model. Furthermore, even after adjusting the potential confounders including sex, age, body mass index, physical activity, energy intake, alcohol, and smoking status, this association remained significant (fully adjusted model: OR, 2.00; 95% CI, 1.17-3.34). Our study revealed a higher ratio of omega-6 to omega-3 was related to a higher likelihood of H. pylori infection. Therefore, it is advisable to maintain a balanced intake of PUFAs in the diet.

Umbilical cord vessels other than the umbilical arteries and vein: a histological study of midterm human fetuses

  • Ji Hyun Kim;Shogo Hayashi;Zhe Wu Jin;Gen Murakami;Jose Francisco Rodriguez-Vazquez
    • Anatomy and Cell Biology
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    • v.55 no.4
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    • pp.467-474
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    • 2022
  • At birth, the umbilical cord contains various types of thin vessels that are near and outside the umbilicus and separate from the umbilical arteries and vein. These vessels are regarded as the remnant "vitelline vessels" and are often called "umbilical vessels", although this terminology could lead to confusion with the true umbilical arteries and vein. No study has yet comprehensively examined these vessels using histological sections. Our examination of these vessels in 25 midterm fetuses (gestational age: 10-16 weeks) led to five major findings: (i) all specimens had umbilical branches of the inferior epigastric artery; (ii) 5 specimens had vitelline vein remnants; (iii) 4 specimens had a thin artery originating from the left hepatic artery that ran along the umbilical vein; (iv) 2 specimens had a so-called "para-umbilical vein" that was along the umbilical vein and reached the umbilicus; and (v) all specimens had lymphatic vessels originating from the umbilicus that ran caudally along the umbilical artery. The pelvic vein tributaries were well developed along the intra-abdominal umbilical artery, but did not reach the umbilicus. The lymphatic vessel was distinguished from the veins by an intraluminar cluster of lymphocytes attaching to the endothelium. The arterial branch in the umbilical cord did not accompany veins and lymphatic vessels, in contrast to the mother artery in the rectus abdominis. All these thin vessels seemed to be obliterated when the fibrous umbilical ring grew during late-term. The para-umbilical collateral vein in adults might develop outside the fibrous umbilical ring after birth.

Diet and Cancer Risk in the Korean Population: A Meta-analysis

  • Woo, Hae Dong;Park, Sohee;Oh, Kyungwon;Kim, Hyun Ja;Shin, Hae Rim;Moon, Hyun Kyung;Kim, Jeongseon
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.19
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    • pp.8509-8519
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    • 2014
  • Many studies have found links between diet and cancer. The summary estimates of the association between dietary factors and cancer risk were investigated using previously reported studies of the Korean population. Gastric cancer risk was inversely associated with the high intake of soy foods [OR (95% CI): 0.32 (0.25-0.40) for soybean, 0.56 (0.45-0.71) for soybean curd, and 0.67 (0.46-0.98) for soymilk], allium vegetables [OR (95% CI): 0.37 (0.26-0.53) for green onion, 0.54 (0.40-0.73) for garlic, and 0.54 (0.35-0.85) for onion], fruits [OR (95% CI): 0.61 (0.42-0.88)], and mushrooms [OR (95% CI): 0.43 (0.21-0.88)]. Salt and Kimchi were associated with an increased gastric cancer risk [OR (95% CI): 1.92 (1.52-2.43) and 2.21 (1.29-3.77), respectively]. Colorectal cancer risk was positively associated with meat intake [OR (95% CI): 1.25 (1.15-1.36)]. Total soy products, soybean curd, and soymilk showed an inverse association with breast cancer risk [OR (95% CI): 0.61 (0.38-0.99), 0.47 (0.34-0.66), and 0.75 (0.57-0.98), respectively]. Green/yellow and light colored vegetables were associated with a reduced risk of breast cancer [OR (95% CI): 0.34 (0.23-0.49) and 0.44 (0.21-0.90), respectively]. Mushroom intake was inversely associated in pre-menopausal women only [OR (95% CI): 0.47 (0.26-0.86)]. In conclusion, soy foods, fruits and vegetables might reduce cancer risk in the Korean population. High salt food might be risk factor for gastric cancer, and intake of high amount of meat might cause colorectal cancer.

The Genetic Variations of Pleurotus spp. on Subculture (느타리버섯 속(Pleurotus spp.)의 계대배양에 따른 유전적 변이)

  • Kang, Kyung-Hong;Song, Ju-Hee;Kim, Hong-Nam
    • The Korean Journal of Mycology
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    • v.30 no.1
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    • pp.23-30
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    • 2002
  • The genetic variations and the rate of mycelial growth in the dikaryon and the monokaryon stages of Pleurotus spp. were surveyed during their subcultures. The highest growth rate was observed on both the 3rd and the 4th subcultures. The remarkably rapid growth rate was detected in P. ostreatus dikaryon. Genetic similarities in the dikaryon and the monokaryon of P. ostreatus were more than 57.5% and 85.7%, respectively, and those of P. eryngii were more than 85.2% and 84.8%, respectively. The genetic similarities of monokaryotic P. ostreatus were higher than those of dikaryotic. The topology of phylogenetic trees showed that the divergence and the clustering patterns of branch did not correlated with the number of subcultures. This suggests that genetic variations occur very randomly on mycelial cultures. These results suggest that the monokaryotic mycelia is genetically more stable than the dikaryotic in subcultures, and that it is very useful to stock monokaryotic mycelia for making spawns and breeding of Pleurotus spp.

A numerical study on the dispersion of the Yangtze River water in the Yellow and East China Seas

  • Park, Tea-Wook;Oh, Im-Sang
    • Journal of the korean society of oceanography
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    • v.39 no.2
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    • pp.119-135
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    • 2004
  • A three-dimensional numerical model using POM (the Princeton Ocean Model) is established in order to understand the dispersion processes of the Yangtze River water in the Yellow and East China Seas. The circulation experiments for the seas are conducted first, and then on the bases of the results the dispersion experiments for the river water are executed. For the experiments, we focus on the tide effects and wind effects on the processes. Four cases of systematic experiments are conducted. They comprise the followings: a reference case with no tide and no wind, of tide only, of wind only, and of both tide and wind. Throughout this study, monthly mean values are used for the Kuroshio Current input in the southern boundary of the model domain, for the transport through the Korea Strait, for the river discharge, for the sea surface wind, and for the heat exchange rate across the air-sea interface. From the experiments, we obtained the following results. The circulation of the seas in winter is dependent on the very strong monsoon wind as several previous studies reported. The wintertime dispersion of the Yangtze River water follows the circulation pattern flowing southward along the east coast of China due to the strong monsoon wind. Some observed salinity distributions support these calculation results. In summertime, generally, low-salinity water from the river tends to spread southward and eastward as a result of energetic vertical mixing processes due to the strong tidal current, and to spread more eastward due to the southerly wind. The tide effect for the circulation and dispersion of the river water near the river mouth is a dominant factor, but the southerly wind is still also a considerable factor. Due to both effects, two major flow directions appear near the river mouth. One of them is a northern branch flow in the northeast area of the river mouth moving eastward mainly due to the weakened southerly wind. The other is a southern branch flow directed toward the southeastern area off the river mouth mostly caused by tide and wind effects. In this case, however, the tide effect is more dominant than the wind effect. The distribution of the low salinity water follows the circulation pattern fairly well.

Size-Specific Dose Estimation In the Korean Lung Cancer Screening Project: Does a 32-cm Diameter Phantom Represent a Standard-Sized Patient in Korean Population?

  • Kim, Eun Young;Kim, Tae Jung;Goo, Jin Mo;Kim, Hyae Young;Lee, Ji Won;Lee, Soojung;Lim, Jun-tae;Kim, Yeol
    • Korean Journal of Radiology
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    • v.19 no.6
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    • pp.1179-1186
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    • 2018
  • Objective: The purposes of this study were to evaluate size-specific dose estimate (SSDE) of low-dose CT (LDCT) in the Korean Lung Cancer Screening (K-LUCAS) project and to determine whether CT protocols from Western countries are appropriate for lung cancer screening in Korea. Materials and Methods: For participants (n = 256, four institutions) of K-LUCAS pilot study, volume CT dose index ($CTDI_{vol}$) using a 32-cm diameter reference phantom was compared with SSDE, which was recalculated from $CTDI_{vol}$ using size-dependent conversion factor (f-size) based on the body size, as described in the American Association of Physicists in Medicine Report 204. This comparison was subsequently assessed by body mass index (BMI) levels (underweight/normal vs. overweight/obese), and automatic exposure control (AEC) adaptation (yes/no). Results: Size-specific dose estimate was higher than $CTDI_{vol}$ ($2.22{\pm}0.75mGy$ vs. $1.67{\pm}0.60mGy$, p < 0.001), since the f-size was larger than 1.0 for all participants. The ratio of SSDE to $CTDI_{vol}$ was higher in lower BMI groups; 1.26, 1.37, 1.43, and 1.53 in the obese (n = 103), overweight (n = 70), normal (n = 75), and underweight (n = 4), respectively. The ratio of SSDE to $CTDI_{vol}$ was greater in standard-sized participants than in large-sized participants independent of AEC adaptation; with AEC, SSDE/$CTDI_{vol}$ in large- vs. standard-sized participants: $1.30{\pm}0.08$ vs. $1.44{\pm}0.08$ (p < 0.001) and without AEC, $1.32{\pm}0.08$ vs. $1.42{\pm}0.06$ (p < 0.001). Conclusion: Volume CT dose index based on a reference phantom underestimates radiation exposure of LDCT in standard-sized Korean participants. The optimal radiation dose limit needs to be verified for standard-sized Korean participants.

Pollicization of the Middle Finger

  • Bahk, Sujin;Eo, Su Rak;Cho, Sang Hun;Jones, Neil Ford
    • Archives of Reconstructive Microsurgery
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    • v.24 no.2
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    • pp.62-67
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    • 2015
  • Purpose: Pollicization typically involves surgical migration of the index finger to the position of the thumb. This procedure facilitates the conversion of a useless hand into a well-functioning one in patients who are not amenable to the toe-to-hand transfer. However, middle finger pollicization has been rarely reported. Materials and Methods: We reconstructed a thumb by immediate pollicization of the remnants of the middle finger in two patients who sustained a tumor and a trauma, respectively. The former, after cancer ablation was performed, has not been reported literally, and the latter involved free devitalized pollicization of the middle finger using a microsurgical anastomosis. The distal third extensor communis tendon was sutured to the proximal extensor pollicis longus tendon and the distal flexor digitorum superficialis and profundus were sutured to the proximal flexor pollicis longus. The abductor pollicis brevis tendon was sutured to the distal end of the first palmar interosseous muscle. Coaptation of the third digital nerve and the superficial radial nerve branch was performed. Results: Patients showed uneventful postoperative courses without complication such as infection or finger necrosis. Based on the principles of pollicization, a wide range of pinch and grasp movements was successfully restored. They were pleased with the functional and cosmetic results. Conclusion: Although the index finger has been the digit of choice for pollicization, we could also use the middle finger on specific occasions. This procedure provides an excellent option for the reconstruction of a mutilated thumb and could be performed advantageously in a single step.

Effects of fresh mineralized dentin and cementum on socket healing: a preliminary study in dogs

  • Kadkhodazadeh, Mahdi;Ghasemianpour, Majid;Soltanian, Negar;Sultanian, Gholam Reza;Ahmadpour, Shahriar;Amid, Reza
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.41 no.3
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    • pp.119-123
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    • 2015
  • Objectives: Dentin is composed of many minerals and growth factors. Based on this composition, we studied its effect as a possible regenerative material for alveolar healing. Materials and Methods: This study was conducted using four 2.5-year-old mongrel dogs (male; weight, 25 to 30 kg). The third mandibular premolars were carefully mobilized with a dental elevator and then removed using forceps. The crown portions of the extracted teeth were removed with cutters, and the root portions of the remaining teeth were collectively trimmed as closely as possible to 350 to $500{\mu}m$. Dentin and cementum (DC) chips harvested from the extracted teeth were soaked in blood and packed into the fresh sockets (autograft). Biopsies were performed at the ends of day 14 and day 56 following implantation. Data were expressed as $mean{\pm}standard$ deviation and compared with t-test results. Results: The ratio of $S_A$(bone) to total area of each probe was determined and was $170{\pm}16{\mu}m^2$ for the control group and $71{\pm}14{\mu}m^2$ for the DC group, a significant difference (P <0.05). Conclusion: DC particulate grafts offered no improvement in bone regeneration in alveolar extraction sockets.

Time-Lapse Video Microscopy of Wound Recovery and Reproduction in the Siphonous Green Alga Derbesia tenuissima

  • Martin, Erika;Jeremy , Pickett-Heaps;Kim, Gwang-Hoon;West, John
    • ALGAE
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    • v.21 no.1
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    • pp.109-124
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    • 2006
  • Responses to various types of mechanically induced wounding were followed in the giant-celled Caulerpalean species, Derbesia tenuissima, using time-lapse video-microscopy. Gametophyte vesicle cells. Puncture wounding: the gametophyte cell seals the puncture in 5 min. This is followed by cycles of ruptures and sealing, ending with full recovery in 24 hrs. Cut wounding: the protoplast immediately retracts away from the wall and reforms an intact, deflated protoplast that expands to fill the original cell within 21 hrs. Crush wounding (internal). When retained within the cell wall many protoplast fragments condense, round up, and coalesce; the reconstituted protoplast expands until it attains complete recovery, filling the original cell shape in 12 hrs. Crush wounding (external). Protoplast fragments extruded from the crushed cell are more numerous and smaller taking longer to recover. Most fragments become spherical, transforming into small viable cells capable of reproduction in several days. Sporophyte filaments. Crush wounding creates many small fragments that initially condense, coalesce and then expand within the wall to restore a complete filament with normal cytoplasmic streaming within 5 hrs. Reproduction: gametophyte. Our culture isolates produce more females than males (30:1). Gametangia develop one day before discharge that occurs explosively (1/6 sec) at first morning light. The vesicle cell forms successive gametangia every 14 days. Sporophyte. Each sporangium develops on a lateral branch that becomes isolated by the creation of successive basal plugs. After cytoplasmic cleavage and differentiation the stephanokont spores are discharged. The spores settle quickly and germinate forming gametophyte cells.

Weather Recognition Based on 3C-CNN

  • Tan, Ling;Xuan, Dawei;Xia, Jingming;Wang, Chao
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.14 no.8
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    • pp.3567-3582
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    • 2020
  • Human activities are often affected by weather conditions. Automatic weather recognition is meaningful to traffic alerting, driving assistance, and intelligent traffic. With the boost of deep learning and AI, deep convolutional neural networks (CNN) are utilized to identify weather situations. In this paper, a three-channel convolutional neural network (3C-CNN) model is proposed on the basis of ResNet50.The model extracts global weather features from the whole image through the ResNet50 branch, and extracts the sky and ground features from the top and bottom regions by two CNN5 branches. Then the global features and the local features are merged by the Concat function. Finally, the weather image is classified by Softmax classifier and the identification result is output. In addition, a medium-scale dataset containing 6,185 outdoor weather images named WeatherDataset-6 is established. 3C-CNN is used to train and test both on the Two-class Weather Images and WeatherDataset-6. The experimental results show that 3C-CNN achieves best on both datasets, with the average recognition accuracy up to 94.35% and 95.81% respectively, which is superior to other classic convolutional neural networks such as AlexNet, VGG16, and ResNet50. It is prospected that our method can also work well for images taken at night with further improvement.