• Title/Summary/Keyword: box

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A novel F-box protein with leucine-rich repeats affects defecation frequency and daumone response in Caenorhabditis elegans

  • Kim, Sung-Moon;Jang, Sang-Ho;Son, Na-Rae;Han, Ching-Tack;Min, Kwan-Sik;Lee, Hak-Kyo;Hwang, Sue-Yun
    • Animal cells and systems
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    • v.16 no.4
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    • pp.280-288
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    • 2012
  • Targeted degradation of proteins through ubiquitin-mediated proteolysis is an important control mechanism in various cellular processes. The process of ubiquitin conjugation is achieved by three enzyme complexes, among which the ubiquitin ligase complex (E3) is in charge of substrate specificity. The SCF (SKP1-CUL1-F-box) family portrays the largest and the most characterized member of the E3 ligases. For each SCF complex, the ubiquitination target is recognized by the F-box protein subunit, which interacts with the substrate through a unique C-terminal domain. We have characterized a novel F-box protein CFL-1 that represents a single LRR-type F-box (FBXL) in the Caenorhabditis elegans genome. CFL-1 is highly homologous to FBXL20 and FBXL2 of mammals, which are known to regulate synaptic vesicle release and cell cycle, respectively. A green fluorescence protein (GFP)-reporter gene fused to the cfl-1 promoter showed restricted expression around the amphid and the anus. Modulation of CFL-1 activity by RNAi affected the time interval between defecations. RNAi-treated worms also exhibited reduced tendency to form dauer when exposed to daumone. The potential involvement of CFL-1 in the control of defecation and pheromone response adds to the ever expanding list of cellular processes controlled by ubiquitin-mediated proteolysis in C. elegans. We suggest that CFL-1, as a single LRR-type F-box protein in C. elegans, may portray a prototype gene exerting diverse functions that are allocated among multiple FBXLs in higher organisms.

An Study on the Analysis of Design Criteria for S-Box Based on Deep Learning (딥러닝 기반 S-Box 설계정보 분석 방법 연구)

  • Kim, Dong-hoon;Kim, Seonggyeom;Hong, Deukjo;Sung, Jaechul;Hong, Seokhie
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.30 no.3
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    • pp.337-347
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    • 2020
  • In CRYPTO 2019, Gohr presents that Deep-learning can be used for cryptanalysis. In this paper, we verify whether Deep-learning can identify the structures of S-box. To this end, we conducted two experiments. First, we use DDT and LAT of S-boxes as the learning data, whose structure is one of mainly used S-box structures including Feistel, MISTY, SPN, and multiplicative inverse. Surprisingly, our Deep-learning algorithms can identify not only the structures but also the number of used rounds. The second application verifies the pseudo-randomness of and structures by increasing the nuber of rounds in each structure. Our Deep-learning algorithms outperform the theoretical distinguisher in terms of the number of rounds. In general, the design rationale of ciphers used for high level of confidentiality, such as for military purposes, tends to be concealed in order to interfere cryptanalysis. The methods presented in this paper show that Deep-learning can be utilized as a tool for analyzing such undisclosed design rationale.

Optimal Joint Position in Concrete Pavement Slab over Skewed Box Culvert (수평으로 경사진 박스암거 위 콘크리트 포장 슬래브의 최적 줄눈위치)

  • Yeom, Woo Seong;Jeong, Ho Seong;Yan, Yu;Sohn, Dueck Soo;Lee, Jae Hoon;Jeong, Jin Hoon
    • International Journal of Highway Engineering
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    • v.15 no.5
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    • pp.47-55
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    • 2013
  • PURPOSES : The purpose of this study is to investigate the optimal joint positions which can minimize distresses of concrete pavement containing box culvert with horizontally skewed angles. METHODS : The concrete pavement containing the box culvert with different skewed angles and soil cover depths was modeled by 3 dimensional finite element method. The contact boundary condition was used between concrete and soil structures in addition to the nonlinear material property of soil in the finite element model. A dynamic analysis was performed by applying the self weight of pavement, negative temperature gradient of slab, and moving vehicle load simultaneously. RESULTS : In case of zero skewed angle ($0^{\circ}$), the maximum tensile stress of slab was the lowest when the joint was positioned directly over side of box culvert. In case there was a skewed angle, the maximum tensile stress of slab was the lowest when the joint passed the intersection between side of the box culvert and longitudinal centerline of slab. The magnitude of the maximum tensile stress converged to a constant value regardless the joint position from 3m of soil cover depth at all of the horizontally skewed angles. CONCLUSIONS : More reasonable and accurate design of the concrete pavement containing the box culvert can be possible based on the research results.

Investigation of residual stresses of hybrid normal and high strength steel (HNHSS) welded box sections

  • Kang, Lan;Wang, Yuqi;Liu, Xinpei;Uy, Brian
    • Steel and Composite Structures
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    • v.33 no.4
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    • pp.489-507
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    • 2019
  • In order to obtain high bearing capacity and good ductility simultaneously, a structural column with hybrid normal and high strength steel (HNHSS) welded box section has been developed. Residual stress is an important factor that can influence the behaviour of a structural member in steel structures. Accordingly, the magnitudes and distributions of residual stresses in HNHSS welded box sections were investigated experimentally using the sectioning method. In this study, the following four box sections were tested: one normal strength steel (NSS) section, one high strength steel (HSS) section, and two HNHSS sections. Based on the experimental data from previous studies and the test results of this study, the effects of the width-to-thickness ratio of plate, yield strength of plate, and the plate thickness of the residual stresses of welded box sections were investigated in detail. A unified residual stress model for NSS, HSS and HNHSS welded box sections was proposed, and the corresponding simplified prediction equations for the maximum tensile residual stress ratio (${\sigma}_{rt}/f_y$) and average compressive residual stress ratio (${\sigma}_{rc}/f_y$) in the model were quantitatively established. The predicted magnitudes and distributions of residual stresses for four tested sections in this study by using the proposed residual stress model were compared with the experimental results, and the feasibility of this proposed model was shown to be in good agreement.

Paperboard Box Laminated with Functional MA Film for Freshness Extension of Squash(Cucurbita moschata) (기능성 필름이 부착된 골판지상자에 포장한 애호박의 신선도에 미치는 효과)

  • 박형우;김상희
    • Food Science and Preservation
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    • v.6 no.4
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    • pp.406-410
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    • 1999
  • Squash(Cucurbita moschata) during 7 days of storage at 2$0^{\circ}C$ were packed with functional MA film laminated in corrugated paperboard box(FC), LDPE pouches and control, and weight loss, firmness, chlorophill contents, vitamin C and marketability was erluated. Weight loss of control was 5.8% after 7 days, and 30LD, 50LD was 0.4%, and FC was 1.2%. Firmness of FC, 30LD and 50LD was higher than that of control. Chlorophill content of squash between control and FC box was 46.43 and 53.66 $\mu\textrm{g}$/ml, that of FC box was 15.6% higher than control. Total ascorbic acid cpntent(TAA) of squash packed with control and FC box were 28.11 and 35.65mg%, TAA of squash packed with FC box was 26.8% higher than that of control. Marketability of squash packed with FC box was better than that of control.

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Critical analysis about the game self-regulation bill: A study about the structure and regulation of Double loot box (확률형 아이템 규제안에 대한 비판적 분석: 이중랜덤박스의 구조와 규제에 대한 연구)

  • Jo, Hui-Seon;Ryu, Seoung-Ho
    • Journal of Korea Game Society
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    • v.19 no.4
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    • pp.49-64
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    • 2019
  • In this paper, we examined the concept of three types of double loot box respectively and analyzed each characteristics of double loot box by game case study. Those types are divided into the following three cases; 1) Double-mileage gacha 2) Double-limited period gacha 3) Kompu gacha. As the result, Double loot boxs are characterized as below: 1) Double loot box has a tendency to combine various type of loot boxes. 2) Double loot box's reward is hard to gain in game, or not to sell in game store. With these features, double loot box could be a gambling sales strategy. To solve this problem, this study suggested that it is essential to revise game self-regulations, enhance the professionalism of monitoring groups, and propel the self-effort of game companies.

Design of Pull Box Members on the Landing Pier Using Finite Element Analysis of a Steel Plate (강재 플레이트 유한요소해석을 이용한 잔교 상부의 풀 박스 부재의 선정)

  • Kim, Sungwon;Hong, Hyemin;Han, Taek Hee;Seo, Seung Nam
    • Journal of Coastal Disaster Prevention
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    • v.4 no.3
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    • pp.111-118
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    • 2017
  • In this study, pull box members were designed by finite element analysis of a steel plate covering a pull box to secure its safety on the landing pier dedicated to the large research survey ship. It was assumed that the maximum load is due to the 250 tonf class crane used for unloading work when the working environment in the upper part of the landing pier was considered. The safety of the pull box was evaluated by the comparison between the yield strength of the steel plate and the result of stress analysis on the steel plate due to the crane load. It was found that the stress at the plate from the crane load exceeded the yield strength of the steel(205MPa) when the upper part of the pull box was protected by a $1950{\times}1950mm$ steel plate cover. In order to compensate for this, a concrete filled steel tube(CFT) column with a diameter of 150 mm and a steel thickness of 10 mm was reinforced at the center of the plate, and the finite element analysis was carried out. However, the maximum stress at the steel plate was higher than the yield strength of the steel in some load cases so that it was tried to find appropriate thickness of the steel plate and diameter of the CFT columns. Finally, the analysis results showed that the safety of the pull box was secured when the thickness of the steel plate and the diameter of the CFT column were increased to 30mm and 180mm, respectively.

Design of AES-Based Encryption Chip for IoT Security (IoT 보안을 위한 AES 기반의 암호화칩 설계)

  • Kang, Min-Sup
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.21 no.1
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    • pp.1-6
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    • 2021
  • The paper proposes the design of AES-based encryption chip for IoT security. ROM based S-Box implementation occurs a number of memory space and some delay problems for its access. In this approach, S-Box is designed by pipeline structure on composite field GF((22)2) to get faster calculation results. In addition, in order to achieve both higher throughput and less delay, shared S-Box are used in each round transformation and the key scheduling process. The proposed AES crypto-processor is described in Veilog-HDL, and Xilinx ISE 14.7 tool is used for logic synthesis by using Xilinx XC6VLX75T FPGA. In order to perform the verification of the crypto-processor, the timing simulator(ModelSim 10.3) is also used.

Numerical Evaluation of Boundary Effects in the Laminar Shear Box System (층 분할된 연성전단상자의 경계효과에 관한 수치해석적 분석)

  • Kim, Jin-Man;Ryu, Jeong-Ho
    • Journal of the Korean Geotechnical Society
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    • v.24 no.8
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    • pp.35-41
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    • 2008
  • Laminar-shear-boxes are widely used to simulate free-field seismic ground response by using a l-g shaking table or geo centrifuge in geotechnical earthquake engineering. This study numerically modeled and compared the ground responses in the free field, rigid box, and laminar shear box by using a 3-D FEM program. It is found from the numerical simulations that the laminar shear box can simulate the free field ground movement more precisely than the rigid box. However, the laminar shear box underestimated the surface acceleration of the free field ground. It also showed low-frequency characteristics probably because the stiffness and inertia effect of surrounding ground are neglected.