• Journal of the Korean Applied Science and Technology
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• v.22 no.1
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• pp.77-83
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• 2005

The influence of fluorescence, scattering, and absorbance in turbid material by light scattering was interpreted by the scattered fluorescence intensity and wavelength. The effect of optical property in scattering media was investigated. It is very important to study the charge coupled device(CCD) in spectrometry because we can use the molecular energy level, molecular structure, absorption or emission, intermolecular reaction, weakly bound molecular energy, photochemistry, fluorescence and photodynamic therapy. CCD is very essential to study the molecular structure and medical engineering combined laser spectroscopy in the modem physical and chemistry. Accordingly, this study has designed and manufactured the electromagnetic spectrometry with CCD, and has analyzed the hematoporphyrin derivative.

• Geomechanics and Engineering
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• v.13 no.2
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• pp.217-235
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• 2017

The stability prediction of shallow buried tunnels is one of the most difficult tasks in civil engineering. The aim of this work is to predict the state of collapse in shallow tunnel in layered soils by employing non-associated flow rule and nonlinear failure criterion within the framework of upper bound theorem. Particular emphasis is first given to consider the effects of dilation on the collapse mechanism of shallow tunnel. Furthermore, the seepage forces and surface settlement are considered to analyze the influence of different dilation coefficients on the collapse shape. Two different curve functions which describe two different soil layers are obtained by virtual work equations under the variational principle. The distinct characteristics of falling blocks up and down the water level are discussed in the present work. According to the numerical results, the potential collapse range decreases with the increase of the dilation coefficient. In layered soils, both of the single layer's dilation coefficient and two layers' dilation coefficients increase, the range of the potential collapse block reduces.

• Journal of the Korean Magnetic Resonance Society
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• v.2 no.2
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• pp.131-140
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• 1998

The calcium-induced structural changes in the skeletal muscle regulatory protein troponin C (NTnC) involve a transition from a ‘closed’to an ‘open’structure with the concomitant exposure of a large hydrophobic interaction site for target proteins. Structural studies have served to define this conformational change and elucidate the mechanism of the linkage between calcium binding and the induced structural changes. There are now several structures of NTnC available from both NMR and X-ray crystallography. Comparison of the calcium bound structures reveals differences in the level of opening. We have considered the concept of a flexible open state of NTnC as a possible explanation for this apparent discrepancy. We also present simulations of the closed-to-open transition which are in agreement with the flexibility concept and with experimental energetics data.

• Korean Journal of Computational Design and Engineering
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• v.2 no.1
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• pp.19-27
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• 1997

This paper presents rough cut tool path planning for the fewer-axis machine consisting of a three-axis CNC machine and a rotary indexing table. In the problem dealt with in this paper, the tool orientation is "intermediately" changed, distinguished from the conventional problem where the tool orientation is assumed to be fixed. The developed rough cut path planning algorithm tries to minimize the number of tool orientation (setup) changes together with tool changes and the machining time for the rough cut by the four procedures: a) decomposition of the machining area based on the possibility of tool interference (via convex hull operation), b) determination of the optimal tool size and orientation (via network graph theory and branch-and bound algorithm), c) generation of tool path for the tool and orientation (based on zig-zag pattern), and d) feedrate adjustment to maintain the cutting force at an operation level (based on average cutting force). The developed algorithms are validated via computer simulations, and can be also used in pure fiveaxis machining environment without modification.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.9
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• pp.4237-4240
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• 2016

Drugs processed using nanobiotechnology may be more biocompatible, with sustainable and stabilised release or action. L-asparaginase produced from fungi has many advantages for treatment of lymphocytic leukemia with lesser side effect. In the present work, maghemite nanobiocomposites of fungal asparaginase were produced using glutaraldehyde-pretreated colloidal magnetic nanoparticles. Formation of nanobiocomposites was observed using laser light scattering and confirmed by UV-visible spectrophotometry with the absorption peak at 497 nm. The specific asparaginase activity was increased from 320 U/mg with crude asparaginase to 481.5 U/mg. FTIR analysis confirmed that primary amines are the functional groups involved in binding of asparaginase on magnetic nanoparticles. The average size of the produced nanobiocomposite was found in the range of 30 nm to 40 nm using histogram analysis. The magnetic nanobiocomposite of asparaginase synthesised using glutaraldehyde showed 90.75% cytotoxicity against human colon adenocarcinoma cell lines. Hence it can be used as an active anticancer drug with an augmented level of bioavailability.

• Elastomers and Composites
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• v.33 no.1
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• pp.17-26
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• 1998

Natural rubber was filled with 8 commercial carbon blacks covering range of rubber-grade products at different levels of filler loadings in order to investigate physical compound and vulcanizate properties. It was found that the curves of rubber property vs filler loading of both uncured compounds and vulcanizates can be superposed to one single master curve by introducing an effective volume fraction which is based on CDBP. The effective volume fraction, $V_{EFF}$ was utilized to explain the variation of the stiffness of all rubber compounds. The surface area-corrected effective volume fraction, V', was utilized to explain the formation of bound rubber, rebound and lambourn wear.

• Journal of Sensor Science and Technology
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• v.24 no.4
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• pp.274-279
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• 2015

This paper describes optimizing fabrication methods for 2-axis electrically levitated MEMS gyroscope. Electrostatically levitated gyroscope has very high potential of performance due to the fact that its proof mass is not mechanically bound to any other structures, but its complex structure and difficulty of fabrication holds back the research that only a few researches have been reported. In this work, fabrication method for glass-silicon-glass 3-floor structure for 2-axis electrically levitated MEMS gyroscope is presented, including simplified multi-level glass etch method utilizing photoresist attack, preventing metal diffusion by adding middle layer of metal electrode, overcoming Deep RIE limitation by separate fabrication of silicon structures and keeping the electrode safe from dicing debris.

• Food Science of Animal Resources
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• v.31 no.3
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• pp.381-388
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• 2011

Dietary conjugated linoleic acid (CLA) play key roles in lipid metabolism. Here, we investigated the effect of CLA on the transcriptional activity of TR4, an orphan nuclear receptor that plays an important role in lipid homeostasis. CLA increased TR4 gene mRNA level in 3T3-L1 adipocytes, but inhibited TR4 transcriptional activity in a dose-dependent manner. TR4 induced perilipin expression in 3T3-L1 adipocytes by activating perilipin promoter activity. In a gel shift assay, TR4 bound direct to the putative TR4 response element in the perilipin promoter. Interestingly, CLA reduced the interaction between TR4 and consensus DR1, a well-known TR4 binding site. Additionally, CLA inhibited TR4-induced perilipin promoter activity in a dose-dependent manner. Together, our results suggest that CLA may play a role in lipid homeostasis in adipocytes by functionally regulating TR4.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.56 no.2
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• pp.389-395
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• 2007

In this paper, we consider the robust non-fragile $H_{\infty}$ output feedback controller design method for uncertain descriptor systems with feedback and observer gain variations. The existence condition of observer-based robust and non-fragile $H_{\infty}$ output feedback controller and the controller design method are Presented on the basis of linear matrix inequality approach. The proposed robust non-fragile $H_{\infty}$ output feedback controller guarantees asymptotic stability, non-fragility, $H_{\infty}$ norm bound within a prescribed level in spite of disturbance, parameter uncertainty, and feedback/observer gain variations.

• Fibers and Polymers
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• v.6 no.4
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• pp.348-354
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• 2005

These days consumers' various demands are accelerating research on apparel manufacturing system including automatic measurement, pattern generation, and clothing simulation. Accordingly, methods of reconstructing human body from point-clouds measured using a three dimensional scanning device are required for apparel CAD system to support these functions. In particular, we present in this study a human body reconstruction method focused on two issues, which are the decision of the number of control point for each sectional curve with error bound and the local knot removal for reducing the unusual concentration of control points. The approximation of sectional curves with error bounds as an approximation criterion leads all sectional curves to their own particular shapes apart from the number of control points. In addition, the application of the local knot removal to construction of human body sectional curves reduces the unusual concentration of control points effectively. The results may be used to produce an apparel CAD system as an automatic pattern generation system and a clothing simulation system through the low level control of NUBS or NURBS.