• Journal of Korea Association of Health Promotion
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• v.3 no.2
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• pp.181-188
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• 2005

Background : Osteopenia has been recognized as one of potential complication of chronic liver diseases. Its correlation with hepatits B virus(HBV) carrier, however, has not been reported. Thus this study was aimed to clarify the relationship between the osteopenia and HBV carrier. Methods : Bone densities in 192 HBV carrier women and 200 healthy women were measured; the lumbar spine and three sites of the proximal femur(neck, Ward's triangle, greater trochanter) by dual-photon absorptiometry. And liver function tests(AST, ALT, Albumin, GGT, ALP) were also performed. Results : Bone densities at the four sites measured, were significantly correlated with one another(r=0.34 to 0.99, P<0.01). Compared with control group, HBV carriers had significant decreases in bone densities of femur(P<0.05), particularly marked at Ward's triangle. A negative correlations between bone densities and serum total alkaline phosphatase were also found(r=-0.44, P<0.01). Conclusions : Osteopenia was more prevalent in HBV carrier, particularly in the groups before-fifties. Serum total alkaline phosphatase was higher in those with reduced bone densities Thus measurement of bone densities seems to be necessary in female HBV carriers.

• The korean journal of orthodontics
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• v.44 no.1
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• pp.36-43
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• 2014

Objective: The purpose of this study was to quantitatively evaluate the cortical bone densities of the maxillary and mandibular alveolar processes in adults with different vertical facial types using cone-beam computed tomography (CBCT) images. Methods: CBCT images (n = 142) of adult patients (20-45 years) were classified into hypodivergent, normodivergent, and hyperdivergent groups on the basis of linear and angular S-N/Go-Me measurements. The cortical bone densities (in Hounsfield units) at maxillary and mandibular interdental sites from the distal aspect of the canine to the mesial aspect of the second molar were measured on the images. Results: On the maxillary buccal side, female subjects in the hyperdivergent group showed significantly decreased bone density, while in the posterior region, male subjects in the hyperdivergent group displayed significantly decreased bone density when compared with corresponding subjects in the other groups (p<0.001). Furthermore, the subjects in the hyperdivergent group had significantly lower bone densities on the mandibular buccal side than hypodivergent subjects. The maxillary palatal bone density did not differ significantly among groups, but female subjects showed significantly denser palatal cortical bone. No significant difference in bone density was found between the palatal and buccal sides in the maxillary premolar region. Overall, the palatal cortical bone was denser anteriorly and buccal cortical bone was denser posteriorly. Conclusion: Adults with the hyperdivergent facial type tend to have less-dense buccal cortical bone in the maxillary and mandibular alveolar processes. Clinicians should be aware of the variability of cortical bone densities at mini-implant placement sites.

• The korean journal of orthodontics
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• v.50 no.3
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• pp.157-169
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• 2020

Objective: The aim of this retrospective study was to evaluate the pre- and postsurgical bone densities at alveolar and extra-alveolar sites following two-jaw orthognathic surgery. Methods: The sample consisted of 10 patients (mean age, 23.2 years; range, 18.0-27.8 years; 8 males, 2 females) who underwent two-jaw orthognathic surgery. A three-dimensional imaging program (Invivo 5) was used with multidetector computed tomography images taken pre- and postoperatively (obtained 32.3 ± 6.0 days before surgery and 5.8 ± 2.6 days after surgery, respectively) for the measurement of bone densities at the following sites: (1) alveolar bone in the maxilla and mandible, (2) extra-alveolar sites, such as the top of the head, menton (Me), condyle, and the fourth cervical vertebrae (C4). Results: When pre- and postsurgical bone densities were compared, an overall tendency of decrease in bone density was noted. Statistically significant reductions were observed in the densities of cancellous bone at several areas of the maxillary alveolar bone; cortical and cancellous bone in most areas of the mandibular alveolar bone; cortical bone in Me; and cancellous bone in C4. There was no statistically significant difference in bone density in relation to the depth of the alveolar bone. In a comparison of the bone densities between groups with and without genioplasty, there was almost no statistically significant difference. Conclusions: Accelerated tooth movement following orthognathic surgery may be confirmed with reduced bone density. In addition, this study could offer insights into bone metabolism changes following orthognathic surgery, providing direction for further investigations in this field.

• Journal of Korean Academy of Oral and Maxillofacial Radiology
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• v.29 no.1
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• pp.161-173
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• 1999

This study was performed to compare the bone mineral densities measured at mandibular premolar area by copper-equivalent image and hydroxyapatite phantom with those measured at radius by dual energy absorptiometry and to evaluate the clinical usefulness of Digital system with slide scanner, copper-equivalent image, and hydroxyapatite phantom. For experiment. intraoral radiograms of 15 normal subjects ranged from 20 years old to 67 old were taken with copper-step wedge at mandibular premolar area and bone mineral densities calculated by conversion equation to bone mineral density of hydroxyapatite were compared with those measured at radius distal 1/3 area by Hologic QDR-1000. Obtained results as follows: 1) The conversion equation was Y=5.97X-0.25 and its determination coefficient was 0.9967. The coefficient of variation in the measurement of copper-equivalent value ranged from 4％ to 8％ and showed high reproducibility. 2) The coefficient of variation in the measurement of bone mineral density by the equation ranged from 7％ to 8％ and showed high reproducibility. 3) The bone mineral densities ranged from 0.35 to 0.79g/cm2 at mandibular premolararea. 4) The correlation coefficient between bone mineral densities at mandibular premolar area and those at radius distal 1/3 area was 0.8965. As summary, digital image analyzing system using copper-equivalent image and hydroxyapatite phantom appeared to be clinically useful to measure the bone mineral density at dental area.

• Korean Journal of Cleft Lip And Palate
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• v.4 no.2
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• pp.69-78
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• 2001

Alveolar cleft exists in 75% of cleft patients, In alveolar cleft patients, alar base is widening, palatal fistular formation, maxillary growth disturbance & tooth loss of adjacent area is raised, Alveolar bone grafting, especially iliac bone grafting, is a general treatment method. As operation timing, bone grafting is classified with primary, early secondary, secondary, & late secondary, Here we report cleft width, marginal bone height, bone resorption rate, grafted shape & bone densities after secondary iliac bone grafting was done in the Dept. of oral and maxillofacial surgery of chonbuk national university hospital. We compared cleft width to bone resorption rate and grafted shape. Also, alveolar bone densities of grafted and contralateral site was compared with Emago 3 package? (Oral Diagonostic System, The Netherlands), The data obtained were analyzed using Spearman's rho coefficients and sign test with SPSS for window, The results were obtained as follows. 1. As alveolar cleft width is increase, bone resorption rate is, too. This relation showed significant difference(P<.01). 2, In proximal & distal area, alvolar cleft width and bone graft contour after bone grafting had a reverse proportional difference. It was not significant difference(P>.05). 3. After 3 month, in bone density results by using Emago 3 package? with periapical standard view, occlusal view & panoramic view, differences between grafted bone and alveolar bone of contralateral site didn't show a significant difference(P>.05). Thus, differences of bone densities in the alveolar bones didn't exist.

• The Journal of Korean Medicine
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• v.24 no.3
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• pp.11-22
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• 2003

Objective : As the average span of human life extends, more and more people are at risk of developing osteoporosis, one of the typical diseases of the aged. This thesis presents the effects of Jeungikgwiryon-tang (Tsengikueijung-tang) on bone density, bone biochemical markers, and fetal calvarial cells (FCC) of Sprague Dawleys (S.D.) rats that have induced osteoporosis. The purpose is to see how Jeungikgwiryon-tang (Tsengikueijung-tang) reduces osteoporosis symptoms. Methods : In the first experiment Sprague Dawleys rats were administered Jeungikgwiryon-tang (Tsengikueijung-tang) for 70 days, once a day. Two different doses were used, creating high-dosed and low-dosed groups. The results were compared with a control group. In the second experiment, Jeungikgwiryon-tang (Tsengikueijung-tang) was applied to fetal calvarial cells (FCC) obtained from fetuses inside pregnant Sprague Dawleys rats. The FCCs from high-dosed and low-dosed groups were compared with those from a control group. Results : 1. Bone densities in Groups A and B increased significantly from a control group. 2. Bone ash densities in Group A showed substantial increase. 3. Calcium and phosphorus in bones in Group A increased significantly. 4. Activity of fetal calvarial cells' division in Groups A and B increased significantly from a control group, and ALP of fetal calvarial cells' formation in Group A increased significantly. 5. Protein and collagen levels of fetal calvarial cells in Group A increased significantly. Conclusion : It was found that Jeungikgwiryon-tang (Tsengikueijung-tang) has a tendency to make significant increases in bone densities by enhancing bone formation and by retarding bone absorption. It was concluded that Jeungikgwiryon-tang (Tsengikueijung-tang) activates osteoblast cells effectively.

• Imaging Science in Dentistry
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• v.30 no.1
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• pp.16-22
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• 2000

Purpose : To evaluate the bone densities measured on copper-equivalent image of cross sectional view of mandibular edentulous premolar area obtained by multifuctional panoramic x-ray machine, PM 2002 CC with transversal slicing system. Materials and Methods: Panoramic cross sectional views with 8 mm focal layer of aluminum step and blocks, of hydroxyapatite (RA) step, 6 HA blocks and copper step wedge having 0.03 mm thickness of each step, and of 3 bone blocks cutted by 8 mm thickness mesiodistally and a dry mandible with copper step wedge were taken by using transversal slicing system in PM 2002 Cc. All reference-equivalent images were made and analyzed by NIH image program. Results: The average copper-equivalent value of cancellous bone of bone blocks on the panoramic cross sectional view was 0.026 ± 0.020 mm Cu. The calculated average bone density was 0.38g/cm². There was no significant difference (P>0.1) between the bone densities on intraoral digital view and on the panoramic digital cross sectional view. Conclusion: The copper-equivalent image of panoramic digital cross sectional view obtained by PM 2002 CC with very thin copper step wedge was supposed to be useful to measure the bone density of cancellous bone of mandible at the premolar edentulous area.

• Imaging Science in Dentistry
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• v.30 no.4
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• pp.259-263
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• 2000

Purpose: Upper cervical vertebrae are commonly imaged together with the jaw bones in panoramic radiography. There have been many studies investigating the possible role of mandible as an indicator of osteoporosis. But the result doesn't show unanimity. This study measured bone densities of mandible and second and third cervical vertebrae to find out any relationship between these two areas. These results may contribute in panorama being used as a screening method in detecting possible osteoporotic patient. Materials and Methods: Randomly selected 226 digitized panoramic images with cervical vertebrae shadows from 156 dental patients between 5 to 80 years of age were used. And the bone densities of second and third cervical vertebrae, apical areas of first and second mandibular molars and interdental areas were measured. The bone density measurements were restricted to the cancellous bone and the average and standard deviations and paired t-tests were done to each measurements. Results: All the measurements were statistically significantly related. The best relationship was found between the third cervical vertebrae and first and second mandibular apical areas. The average and standard deviations of the measured bone density ratios of these areas were 1.20±0.45 and 1.34±0.48 each. Conclusion: Patients whose panoramic bone density of the third cervical vertebrae are much below those of mandibular first or second molar apical areas may have osteoporosis.

• Journal of Physiology & Pathology in Korean Medicine
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• v.23 no.6
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• pp.1508-1512
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• 2009

This study was designed to analyze the results of bone mineral density test in oriental medical examination. The subjects were workers in the automobile manufacturing industry. The subjects consisted of 3,206 industrial workers who had received oriental medical examination by oriental medicine and they submitted questionnaires about drinking history and smoking history, during 9 months from March to November. They were categorized by sex, age, job class, drinking history, smoking history and exercise history. The T-scores were measured by using OSTEOPRO(BMTECH, Seoul, Korea). We analyzed the relationship between sex, age, job class, drinking history, smoking history, exercise history and the results of bone mineral density using X2-test of the SPSS Ver. 14.0. There was a positive correlation between age and osteoporosis prevalence. In job class, sales personnel were apt to have a higher prevalence of osteoporosis than factory workers and office workers. Osteoporosis rates of the drinker group showed a higher level than the non-drinker group. Bone mineral densities of non-smoker group were higher than the Smoker group. And bone mineral densities of exerciser group were higher than the non-exerciser group. They have to encourage exercise and educate the workers to quit smoking for their health promotion. Furthermore, continuous health check up needs to be done connectedly.

• Korean Journal of Community Nutrition
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• v.7 no.3
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• pp.327-335
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• 2002

This study was performed to investigate the relationships among bone mineral densities (BMD), anthropometric data and lifestyle factors in the elderly. Subjects included 138 elderly (male: 38, female: 100) aged over 65 years, who were home-(dwelling in a low-income area of Puchon City. The BMDs of the lumbar spines (LS), femoral necks (FN), Ward′s triangles (WT) and trochanters (TC) were measured by dual energy X-ray absorptiometry. The females showed significantly lower BMDs in four sites (p < 0.0001) . The elderly aged over 75 revealed significantly more decreased femoral BMDs than the elderly aged 65 to 74. Female with BMIs of 20 to 25, showed significantly higher BMDs in LS, FN and trochanter than those with BMIs of less than 20. However, males displayed significantly higher BMDs in only LS with increasing BMIs. THe BMDs of LS correlated with weights (r = 0.543, p < 0.001), heights (r = 0.477, p < 0.001), upper arm circumferences (r=0.368, p < 0.01), waist circumferences (r=0.367, p < 0.001), subscapular skinfold thicknesses (r=0.363, p < 0.001) and flip circumferences (r=0.231, p < 0.01). Non-smokers and non-drinkers shelved significantly higher BMDs in trochanters only in the case of the males. Female milk-drinkers showed significantly elevated LS BMDs. Eighteen percent of the males were assessed as having osteoporosis, as compared to fifty percent of the females. Ninety-three percent of the females and 81.6% of the males responded that they often or always had "difficulty in standing for a long time".