• Title/Summary/Keyword: bone and skin

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BONE HEALING CAPACITY OF THE COLLAGEN BONE FILLER ($TERUPLUG^{(R)}$) AND RHBMP-2 IN THE RABBIT CRANIUM DEFECT (가토 두개골 결손부에 이식된 Collagen bone filler ($TERUPLUG^{(R)}$) 및 rhBMP-2의 골치유 능력)

  • Kim, Ju-Hoon;Kim, Chul-Hwan;Kim, Kyung-Wook
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.34 no.2
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    • pp.119-130
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    • 2008
  • Absorbable atelo-collagen sponge $TERUPLUG^{(R)}$, Termo Co. Tokyo, Japan) is inserted in the extraction wound where alveolar bone is exposed. It protects wounds and promotes the formation of granulation. This is made of atelo-collagen, to minimize antigenicity, which is cross-linked by heat treatment for biocompatibility. $TERUPLUG^{(R)}$ consists of between 85 and 95 % of collagen type I and between 5 to 15 % of collagen type III. The raw material for the collagen is derived from bovine skin. It features a sponge block design and is shaped for easy insertion in the extraction wound. This study was designed to find out the bone healing capacity of $TERUPLUG^{(R)}$. We implanted $TERUPLUG^{(R)}$ (experimental group I) and $TERUPLUG^{(R)}$ with rhBMP-2 (experimental group II) in the rabbit cranium defect and then histologically analysed the specimen. The results were as follows. 1. In the 4 weeks, a lot of the newly formed collagen fibers around material of the experimental group I implanted $TERUPLUG^{(R)}$ were observed. But, in the experimental group II implanted $TERUPLUG^{(R)}$ with rhBMP-2, a little of newly formed collagen fibers around material were observed. The cell proliferating activity and apoptosis of the experimental group I, II was positive in and around the implanted material. 2. In the 8 weeks, the amount of newly formed and matured bone in the experimental group II was more observed than the experimental group I and control group. The results of this study indicate that absorbable atelo-collagen sponge ($TERUPLUG^{(R)}$) is relatively favorable bone void filler with biocompatibility and has the better bone healing capacity in case of application with rhBMP-2.

Case of Mental Retardation Associated with Aplasia Cutis Congenita and Skull Defect

  • Cho, Hyun Chul;Hwang, Jong Hee
    • Neonatal Medicine
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    • v.28 no.1
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    • pp.48-52
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    • 2021
  • Aplasia cutis congenita (ACC) is a rare congenital disorder characterized by skin defects involving the epidermis, dermis, subcutaneous tissue, bone, and sometimes dura. It commonly affects the scalp in approximately 70% of cases, but the neck, trunk, and the extremities can also be affected. ACC can occur either as an isolated condition or associated with other anomalies and congenital syndromes, and it can be acquired either genetically or sporadically. Morbidity and mortality are associated with the defects of skull bone, dura, and other multiple anomalies. We herein report the case of a female infant, with a large scalp defect accompanied by a skull defect noted at birth, who developed mental retardation in the preschool years.

Hemangiopericytoma Treated by Surgery with Radiation Therapy in a Dog (개의 혈관외피세포종의 수술적 및 방사선요법 치료례)

  • 홍성혁
    • Journal of Veterinary Clinics
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    • v.18 no.1
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    • pp.82-84
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    • 2001
  • An 11 kg, 7-year-old male pug dog with lameness and tumor of the 2-3rd interdigital portion of the right forelimb was referred to the Veterinary Medical Center of the Tokyo University. On the clinical examination findings, the tumor size was $3{\times}3 cm but alopecia and necrosis were not found. On the radiological findings, a bone lysis was found in the phalanges of digit II of the right forelimb but pulmonary metastasis was not found. The mass was removed with metacarpal bone. Histopathological examination of the mass revealed highly differentiated hemangiopericytoma. Two weeks after the operation, the dog was irradiated by orthovoltage radiation. The source of irradiation was 300 kV, 4mA, 4Gy and a focal spot to skin distance of 40 cm using 1.0 Cu, 1.0Al filter. The radiation therapy was performed twice a week for 5 weeks. The dog showed no recurrence and no metastasis. It was thought that the surgery and radiation therapy treatment was quite a useful method to treat a canine heman-giopericytoma.

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The Combined Scapular and Latissimus Dorsi Free Flap (견갑피판과 광배근피판의 이중유리피판이식술)

  • Chung, Duke-Whan;Han, Chung-Soo;Kwon, Young-Ho
    • Archives of Reconstructive Microsurgery
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    • v.7 no.1
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    • pp.41-46
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    • 1998
  • Microvascular free tissue transfer technique is widely accepted for reconstruction of extensive soft tissue defects on the extremities. The system of flap based on the subscapular artery and vein provides the widest ways of composite free flaps. The possible flaps that can be harvested based on this single vascular pedicle include the scapular and parascapular skin flaps, the serratus anterior and latissimus dorsi muscular flaps, the lateral scapular bone flap, the latissimus dorsi-rib flap, and the serratus anterior-rib flap. This combined flap is available to mutiple tissue defects or complex defects because it can incorporated with skin, muscle and bone flaps. A strikig advantage is the independent vascular pedicles of each components, which allow freedom in orientation of each components. So, it can be freely applied to any forms of three demensional defects on the upper and lower extremities. The combination of scapular cutaneous flap and latissimus dorsi musculocutaneous flap can be resurfaced for massive cutaneous defects on the extremities. We report the use of the combined scapular and latissimus dorsi free flap in seven patients to reconstruct massive deefcts on the extremities. There was no flap failure and little complications and disadvantages. The anatomy of this flap is reviewed and the indication and advantages are discussed.

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Research on Reproduction for Baekje Armor Display -Focus on the Lamellar Armors of the Baekje Hanseong Era- (백제 갑옷 전시를 위한 재현 제작에 관한 연구 -한성 시기 찰갑을 중심으로-)

  • Chae, Keum Seok;Kim, So-Hee
    • Journal of the Korean Society of Clothing and Textiles
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    • v.41 no.2
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    • pp.281-295
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    • 2017
  • This research is about the reproduction of Baekje's armor-lamellar made for the Hanseong Baekje Museum exhibition. The purpose of the research are as follows. First, to categorize Baekje armor by type based on ancient documents and the excavated relics. Second, to reproduce categorized armor that provide a visual work for use in diverse areas. Baekje armor can be examined through the ancient records and several excavated relics. The results of the research are as follows. First, Baekje armor can be categorized into four types by material: 1) brass 2) iron 3) leather 4) bone. The can also be categorized into three types by finishing a) Hyeongnyubongnyun type (the leather skin interweaves with the lamellar armor method) b) Hyeokpobongnyun type (the method which wraps around the edges of leather skin) c) leather cloth added to clothe type. Second, we reproduced metal armor, iron armor and leather armor using brass, iron and leather (but not bone). Each type of armor were made life-size for exhibition purposes. We used Hyeongnyubongnyun method, Hyeokpobongnyung method and leather cloth; in addition, reproductions were made based on the Yangdang method that connected the front and the back from both sides of the shoulders so it can be open and close at the side part.

The Etiology and Treatment of the Softened Phallus after the Radial Forearm Osteocutaneous Free Flap Phalloplasty

  • Kim, Seok-Kwun;Kim, Tae-Heon;Yang, Jin-Il;Kim, Myung-Hoon;Kim, Min-Soo;Lee, Keun-Cheol
    • Archives of Plastic Surgery
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    • v.39 no.4
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    • pp.390-396
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    • 2012
  • Background The radial forearm osteocutaneous free flap is considered to be the standard technique for penile construction. One year after their operation, most patients experience a softened phallus, so that they suffer from difficulties in sexual intercourse. In this report, we present our experience with phalloplasty by radial forearm osteocutaneous free flap, as well as an evaluation of the etiology and treatment of the softened phallus. Methods Between March 2005 and February 2010, 58 patients underwent phalloplasty by radial forearm osteocutaneous free flap. Most of their neophallus had been softened subjectively and among them, 12 patients who wanted correction were investigated. We performed repetitive fat injection, artificial dermis grafting, silicone rod insertion, and rib bone with cartilaginous tip graft. Physical examination, plain radiograph, computed tomography, bone scintigraphy, and satisfaction scores were investigated. Results Most of the participants' penises have been softened after phalloplasty, and the skin elasticity had been also decreased. On plain radiograph, the distal end of the bone was self-rounded; however, the bone shape of the neophallus had no significant interval changes or resorption. Computed tomography showed equivocal density of cortical bone. On bone scintigraphy, the bone metabolism was active at 3 months postoperatively, and remained active 9 years postoperatively. Conclusions The use of a rib bone with cartilaginous tip graft could be an option for improvement of the softened phallus. Silicon rod insertion is also worth considering for rigidity of the softened phallus. Decreased rigidity due to soft tissue atrophy could be alleviated with repeated fat injection and artificial dermis grafting.

Muscle Flap Operation in Complicated Bone Tuberculosis Infection -A case report- (골감염을 동반한 결핵 감염에서의 근판 전이술 -치험 1례)

  • 허진필
    • Journal of Chest Surgery
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    • v.31 no.1
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    • pp.89-91
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    • 1998
  • Tuberculosis infection is wide spread disease and makes troublesome complications in some cases. A 50 - year old male visited Andong Hospital with coughing and sputum, dyspnea on exertion, bulging left anterior chest wall mass. Chest X-ray showed right pleural effusion, both side streaky infiltraion, and pleural thickness in apex. Chest CT scan showed bone destruction of left clavicle head, manubrium and large abscess pocket in pectoralis muscle. In May 1996 he underwent en bloc resection of left upper anterior chest wall including pectoralis major and minor muscle, left clavicle head, manubrium and covering infected skin, then contralateral pectoralis major muscle flap and skin graft was done. Patient shows no evidence of recurrence during follow up.

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Handling of Harvested Broiler (육계 출하 후 관리)

  • Kim Dong-Hun;Yoo Young-Mo;Cho Soo-Hyun;Park Beom-Young;Kim Yong-Kon;Lee Jong-Moon
    • Food Science of Animal Resources
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    • v.24 no.4
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    • pp.424-432
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    • 2004
  • The handling and transport of broiler birds from farm to the processing factory is known to cause injury and dead. The preslaughter period can be compromised through thermal stress, emotional stress, starvation, dehydration, metabolic exhaustion, trauma to the skin and bone fraction resulting in bruising and dead. This paper focuses on the control points of individual post Harvest stages by reference to recent literature. In catching, the injuries and deads are caused from fracture of bone, skin damage and hipbone dislocation. It can be improved by training the catchers. The primary factor of dead during transportation is from thermal stress. It is related to stocking density, type of crate and vehicle, ventilation and transportation time. Of the factors, the ventilation is very important. The holding place should be built with consideration of protection from the hostile external environment. There were not much progresses in this area, however, many researches are conducting to focus on animal welfare in European Union. Recently, it is rapidly changed in marketing custom from whole carcass to portion cut in Korea. This means the increase of economic loss due to the mishandling at post harvest. The systematic approach is demanded for this area.

Reverse Dorsalis Pedis Flap Based on the Distal Communicating Artery of the Dorsalis Pedis Artery for the Reconstruction of the Forefoot Defect (원위교통동맥 기저 역행성 족배피판을 이용한 전족부 결손의 재건)

  • Kwon, Chan;Cho, Sang Hun;Eo, Su Rak
    • Archives of Reconstructive Microsurgery
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    • v.22 no.1
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    • pp.38-41
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    • 2013
  • A 31-year-old female patient presented with a skin and soft tissue defect measuring $8{\times}6cm$ in size with exposure of the extensor hallucis longus tendon and the first metatarsal bone after metatarsal lengthening for brachymetatarsia. The defect was covered with a distally based dorsalis pedis flap based on the distal communicating branch of the dorsalis pedis artery. Secondary defect was covered by a split thickness skin graft. There was congestion of the flap tip after the operation; however, it was resolved using medical leeches and anti-coagulants. No necrosis or infection was encountered and the contour of the flap was satisfactory. There was no donor site morbidity. Reverse dorsalis pedis flap has not been commonly used due to the anatomical variation and uncertainty, which is different from the reverse radial forearm flap. However, when faced with the challenge of a moderate soft tissue defect of the distal forefoot, we believe that the reverse dorsalis pedis flap offers a good option with various advantages.

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Ultrasound-Guided Closed Reduction of Nasal Bone Fracture (초음파를 이용한 비골 골절의 비관혈적 정복술)

  • Yang, Hyung Eun;Park, Eun Soo;Cha, Jang Gyu;Kim, Cheol Han;Kim, Jun Hyuk;Kim, Yong Bae
    • Archives of Plastic Surgery
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    • v.34 no.4
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    • pp.461-465
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    • 2007
  • Purpose: Nasal bone fracture may be the most common fracture among facial trauma. However, diagnosis and treatment tend to be overlooked while the reduction and maintenance of fragments remain complicated. Thus, the results are plagued with high rate of nasal deformity which leads cosmetic and functional discomfort. We took advantage of the fact that the nasal bone is one of the thinnest facial bone while at the same time being located close to the skin and utilized ultrasound in performing reduction of nasal bone. Methods:This method was performed on 25 patients with nasal bone fracture. The CL 15-7 linear array transducer (10-15MHz) ultrasound which provides a total of 7 views (3 axial views and 4 transverse views) of the elevator under the bony fragments was enough for the surgeon to accurately perform the reduction. Results: In our class, an accurate and precise reduction has been made possible by real time images before, during, and after the procedure with the help of ultrasound while reducing the exposure to radiation. Conclusion: Compared to previous methods, satisfaction of patients has increased in the nasal tip, minimal fracture of the side wall and secondary reduction cases. Therefore, the incorporation of ultrasound in the closed reduction of nasal bone may prove to be a useful method.