• 대한한방소아과학회지
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• 제23권2호
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• pp.131-144
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• 2009

Objectives : The purpose of this study is to have better data and to make efficient clinical reviews on pre-school children's growth based on two measurements; Body composition for measuring body volume and bone age for potential growth. Methods : The study was conducted with 221 children(118 of boys and 103 of girls) from three kindergartens. Body compositions(soft lean mass, body fat mass, percent body fat) were measured by bioelectrical impedance analysis, bone age was measured by bone density through ultrasonic image of calcaneus. Results and Conclusions : 1. The higher level on weight or BMI, the more averages of soft lean mass, body fat mass, percent body fat. 2. The average bone ages and bone age-chronological age were lower in under 50 percentile's group, but it was higher in upper 50 percentile's group. Also, children with high BMI had older in bone ages and bone age-chronological age. 3. The higher in height percentile based on the bone age; there were more soft lean mass. 4. The averages of bone age and bone age-chronological age were significantly decreased, the more percentiles of height according to bone age were big, they were higher than total average in under 50 percentile's group of height, lower than total average in over 50 percentile's group of height in both boys and girls. 5. The average of MPH were significantly decreased in top percentiles of children's height distribution. Also, in the upper percentiles of height distribution based on bone age were big in only boys. 6. The body compositions(soft lean mass, body fat mass, percent body fat) were related to body volume growth, which can he measured by weight or BMI. The bone age, bone age-chronological age, and MPH were related in terms of hight. The body volume growth was a little hit related with potential growth.

• 대한영상의학회지
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• 제83권5호
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• pp.1081-1089
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• 2022

목적 Greulich-Pyle 기반 전산화된 손 골연령과 팔꿈치 골연령을 비교하고자 하였다. 대상과 방법 팔꿈치 골연령이 Sauvegrain 방법에 의해 평가 가능한 범위 내에 있고, 동시에 손 X선 사진을 촬영한 2126명의 환자(여아 1525명, 남아 601명)를 대상으로 하였다. VUNOMedBoneAge 소프트웨어를 이용하여 손의 1순위 골연령과 VUNO 점수를 얻었으며, 아동의 성별과 1순위 골연령 확률에 따라 손 골연령과 팔꿈치 골연령의 상관관계를 분석하였다. 결과 VUNO 점수와 팔꿈치 골연령의 상관관계(r = 0.898)가 1순위 골연령과 팔꿈치 골연령의 상관관계(r = 0.879)보다 높았다. 1순위 골연령 확률이 70% 미만이거나 여아인 경우, VUNO 점수를 사용하면 팔꿈치 골연령과 더 좋은 상관관계를 보였다. 팔꿈치 골연령은 손 골연령보다 진행된 경향을 보였으며 그 차이는 사춘기 중반까지 증가하다가 후반에 점차 감소하였다. 결론 사춘기 시기의 Greulich-Pyle 기반 전산화된 손 골연령은 팔꿈치 골연령과 유의한 상관관계를 보였다. 다만 팔꿈치 골연령은 손 골연령보다 빠른 경향이 있어 사춘기의 골연령 판단에 있어 주의가 필요하겠다.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제23권1호
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• pp.89-97
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• 2020

Purpose: Obese children may often present with advanced bone age. We aimed to evaluate the correlation between factors associated with childhood obesity and advanced bone age. Methods: We enrolled 232 overweight or obese children. Anthropometric and laboratory data, and the degree of nonalcoholic fatty liver disease (NAFLD) were measured. We analyzed factors associated with advanced bone age by measuring the differences between bone and chronological ages. Results: The normal and advanced bone age groups were comprised of 183 (78.9%) and 49 (21.1%) children, respectively. The prevalence of advanced bone age significantly increased as the percentiles of height, weight, waist circumference, and body mass index (BMI) increased. BMI z-score was higher in the advanced bone age group than in the normal bone age group (2.43±0.52 vs. 2.10±0.46; p<0.001). The levels of insulin (27.80±26.13 μU/mL vs. 18.65±12.33 μU/mL; p=0.034) and homeostatic model assessment-insulin resistance (6.56±6.18 vs. 4.43±2.93; p=0.037) were significantly higher, while high density lipoprotein-cholesterol levels were lower (43.88±9.98 mg/dL vs. 48.95±10.50 mg/dL; p=0.005) in the advanced bone age group compared to those in the normal bone age group, respectively. The prevalence of advanced bone age was higher in obese children with metabolic syndrome than in those without (28.2% vs. 14.7%; p=0.016). The prevalence of advanced bone age was higher in obese children with a more severe degree of NAFLD. Conclusion: Advanced bone age is associated with a severe degree of obesity and its complications.

• 대한한방소아과학회지
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• 제22권2호
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• pp.69-80
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• 2008

Objectives : The purpose of this study was to evaluate the correlation of 3 methods of bone age measurements. Methods : 102 children(49 boys, 53 girls) were involved in this study. We measured the height, weight and bone age based when they visited for the first time. We measured bone age using BoneAge of Sunlight Co.,Ltd. Two of the bone age measurement methods, Greulich-Pyle and Tanner-Whitehouse, were used to analyze the left dorsopalmar hand-wrist radiographs of 102 children who visited in Department of Pediatrics, O O University Oriental Hospital. This study was designed to investigate the correlation of the bone age between two methods. Results : The bone ages were related with age, height, weight and BMI according to this study(P<0.01). Each bone age assessment method had statistically significant correlation to each other(P<0.01). Conclusions : The ultrasound transonic velocity of inferior radiocarpal joint will become a sufficient diagnostic tool of bone age assessment if measurement error can be minimized by proper effort.

• Asian-Australasian Journal of Animal Sciences
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• 제25권7호
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• pp.994-1002
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• 2012

An experiment was carried out to determine the effect of age and caponization on the development blood and bone characteristics development in male country chickens in Taiwan. A total of two hundred 8-wk-old LRI native chicken cockerels, Taishi meat No.13 from LRI-COA, were used as experimental animals. Cockerels were surgically caponized at 8 wks of age. Twelve birds in each group were bled and dressed from 8 wks to 35 wks of age at 1 to 5 wk intervals. The results indicated that the plasma testosterone concentration was significantly (p<0.05) lower in capons after 12 wks of age (caponized treatment after 4 wks) than that of the intact males. The relative tibia weight, bone breaking strength, cortical thickness, bone ash, bone calcium, bone phosphorus and bone magnesium contents were significantly (p<0.05) higher in intact males, while capons had higher (p<0.05) plasma ionized calcium, inorganic phosphorus and alkaline phosphatase concentration. The plasma testosterone concentration, relative tibia weight, tibia length, breaking strength, cortical thickness, bone ash, calcium, and phosphorus contents of intact males chickens increased significantly (p<0.05) with the advance of age. In addition, the relative tibia weight of capons peaked at 18 wks of age, and declined at 35 wks of age. The bone ash, calcium and phosphorus content increased most after 14 wks of age in male native chickens in Taiwan. Also, tibia length and cortical thickness peaked at 22 wks of age. However, the peak of bone strength was found at 26 wks of age. These findings support the assertion that androgens can directly influence bone composition fluxes in male chickens. Caponization caused a significant increase in bone loss at 4 wks post treatment, which reflected bone cell damage, and demonstrated reductions in the relative tibia weight, breaking strength, cortical thickness, bone ash, calcium, phosphorus and magnesium contents, and increases in plasma ionized calcium, inorganic phosphorus and alkaline phosphatase concentration.

• Korean Journal of Radiology
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• 제22권5호
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• pp.792-800
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• 2021

Bone age assessments are a complicated and lengthy process, which are prone to inter- and intra-observer variabilities. Despite the great demand for fully automated systems, developing an accurate and robust bone age assessment solution has remained challenging. The rapidly evolving deep learning technology has shown promising results in automated bone age assessment. In this review article, we will provide information regarding the history of automated bone age assessments, discuss the current status, and present a literature review, as well as the future directions of artificial intelligence-based bone age assessments.

• 대한한방소아과학회지
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• 제20권3호
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• pp.23-32
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• 2006

Objectives : The object of this study was to evaluate the effect of oriental medical treatment to the growth of children using bone age as measurer. Methods : This clinical study has been carried out with 32 cases(male 15, female 17 of children) aging from 7 to 15 years old, who visited to the Department of Pediatrics growth clinic, ○○ medical center from January 2004 to August 2006 and were treated for more than 12 months. Their height, body weight, body mass index(BMI) and bone age were estimated at two points: Before and after oriental medical treatment was applied. Bone age is measured by X-ray image of growth plate in inferior radiocarpal joint. Results : Bone age correlated with choronological age, height, weight. Difference between bone and choronological age was correlated with percentile of height and weight. The mean growth of children showed 4.03 percentile upwardly(p=.046), and difference between bone and choronological age was reduced from $0.23{\pm}1.62$ to $-0.026{\pm}1.64(p=.040)$ after treatment. Conclusions : This study shows that oriental medical treatment helped growth of children using bone age as measurer.

• 식품보건융합연구
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• 제8권2호
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• pp.15-27
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• 2022

This study aims to analyze the relative importance of bone age and chronological age in physique according to gender and to identify the relative importance of bone age, chronological age, and physique in physical fitness and motor coordination according to gender in order to alleviate the imbalance between physique and physical fitness in children. A total of 666 children(346 males, 320 females) between the ages of 11-14 were enrolled as subjects, and the skeletal maturation The skeletal maturation were measured by taking hand-wrist. Physical fitness were measured through a total of 4 components: muscular strength. The results of this study. First, physique variables for both males and females aged 11-14 were found to be more significant predictors of bone age than chronological age. Second, for physical fitness in males, in the order of %fat, body water, waist-hip ratio, weight, fat-free mass, and chronological age were more significant predictor variables; and in females, in the order of %fat, fat-free mass, height, chronological age, weight, bone age, fat mass, and body water were more significant predictor variables. For bone age and chronological age in physical fitness, bone age in males and chronological age in females found to be the more representative variables respectively.

• 대한한방소아과학회지
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• 제22권2호
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• pp.155-170
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• 2008

Objectives : The purpose of this study was to have better data and to make efficient clinical reviews about children's growth based on two methods; X-ray of hand, and ultrasound of calcaneus. Methods : The study was composed of 100 patients(50 of boys and 50 of girls) who visited in department of pediatrics, O O university oriental hospital considering growth and their development. Bone age was measured by the TW3 method's RUS score in simple X-ray image of hand and bone density through ultrasonic image of calcaneus. To predict children's estimated height, their parent's height, bone age, and present height's percentile was measured. Results and Conclusions : 1. The bone age results from X-ray image of hand and ultrasonic image of calcaneus were correlated. Younger children have older bone age from hand's X-ray than the one from calcaneus's ultrasound. Older children have older bone age from calcaneus's ultrasound than one from hand's X-ray. 2. Predicted adult height by bone age(BH) of hand's X-ray and BH of calcaneus's ultrasound were correlated, but predicted adult height by inheritance(IH) was not correlated with others. 3. Bone age and predicted adult height were correlated with age, height, weight, BMI, and especially with age and height. 4. Measuring bone age by X-ray image of hand and ultrasonic image of calcaneus was simple and effective way of estimating children's growth and development.

• 대한기계학회논문집A
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• 제28권10호
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• pp.1451-1457
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• 2004

Bone density parameters of children, unlike that of adult, might reflect growth effect along longitudinal direction as well as bone mass. The clinical test was performed for 859 male/female children with age 6-16 years. Ultrasonic imaging system was used to measure bone density, and relationship of bone density to age was evaluated. The bone quality index appeared to be highly correlated with age for male/female children. It was found that bone quality index rose rapidly in the first growth period. The bone quality index was then kept almost unchanged in the period of puberty, and slowly rose after puberty. It was also found that growth of female stopped earlier than that of male. Also, if more clinical examinations are performed by applying various sizes of region of interest, relationship between bone density and age is expected to be more reliable.