• YAKHAK HOEJI
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• v.51 no.6
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• pp.482-489
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• 2007

Kaempferitrin, isolated from Kenaf (Hibiscus cannabinus), was examined to evaluate its modulatory effects on antigen-presenting cell functions of macrophages/monocytes such as phagocytosis of foreign materials, up-regulation of costimulatory molecules (CD40, CD80 and CD86), adhesion molecule activation, and antigen processing and presentation. Kaempferitrin strongly blocked up-regulation of CD40, CD80 and CD86, but not pattern recognition receptor (PRR) (e.g., TLR2). It also suppressed functional activation of CD29 (${\beta}1$-integrins), as assessed by cell-cell adhesion assay, required for T cell-antigen-presenting cell (APC) interaction. Furthermore, this compound did not block a simple activation of CD29, as assessed by cell-fibronectin adhesion assay. However, the compound did not diminish phagocytic uptake, an initial step for antigen processing, and ROS generation in RAW264.7 cells. In particular, to understand molecular mechanism of kaempferitrin-mediated inhibition, the regulatory role of LPS-induced signaling events was examined using immunoblotting analysis. Interestingly, this compound dose dependently suppressed the phosphorylation of $I{\kappa}B{\alpha}$, Src, Akt and Syk, demonstrating that it can negatively modulate the activation of these signaling enzymes. Therefore, our data suggested that kaempferitrin may be involved in regulating APC function-relevant immune responses of macrophages and monocytes by regulating intracellular signaling.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.27 no.6
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• pp.523-527
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• 2005

Allograft donations are commonly found to be contaminated. The most of tissue banks has promoted the use of ionizing radiation for the sterilization of biological tissues. The potential for transmission of human infectious diseases and contamination of microorganism has created serious concern for the continued clinical use of hard and soft-tissue allografts. Tissue banks have employed 15-25kGy for sterilization of hard and tendon allografts, which, according to the national standards, approaches the level at which the tissue quality is adversely affected for transplantation. The donations of allogeneic tissues to the Korea Tissue Bank over a 2-year period were reviewed, and the incidence and bacteriology of contamination were detailed. Clinical outcomes were determined for donors who had positive cultures at the time of retrieval and during the processing and they were compared with those of post sterilization. After exposure of the frozen block bone to 25kGy and the processed tissues to 15kGy of gamma irradiation, the authors were able to demonstrate complete inactivation of the bacteria. The aim of this study was to obtain the effects of gamma irradiation and the irradiation dose according to the type of tissue, through conventional microbiologic test without on influence of biocompatibility in allografts. The contamination rate after the final irradiation sterilization is 0% in the processed allografts. This may be due to the fact that the gamma radiation and processing steps are effective to control contamination.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.36 no.3
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• pp.103-110
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• 2014

Purpose: The current gold standard for clinical jawbone formation involves autogenous bone as a graft material. In addition, demineralized dentin can be an effective graft material. Although demineralized dentin readily induces heterotopic bone formation, conventional decalcification takes three to five days, so, immediate bone grafting after extraction is impossible. This study evaluated the effect of vacuum ultrasonic power on the demineralization and processing of autogenous tooth material and documented the clinical results of rapidly processed autogenous demineralized dentin (ADD) in an alveolar defects patient. Methods: The method involves the demineralization of extracted teeth with detached soft tissues and pulp in 0.6 N HCl for 90 minutes using a heat controlled vacuum-ultrasonic accelerator. The characteristics of processed teeth were evaluated by scanning electron microscopy (SEM), and energy dispersive X-ray spectroscopy (EDS). Bone grafting using ADD was performed for narrow ridges augmentation in the mandibular area. Results: The new processing method was completed within two hours regardless of form (powder or block). EDS and SEM uniformly demineralized autotooth biomaterial. After six months, bone remodeling was observed in augmented sites and histological examination showed that ADD particles were well united with new bone. No unusual complications were encountered. Conclusion: This study demonstrates the possibility of preparing autogenous tooth graft materials within two hours, allowing immediate one-day grafting after extraction.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.44 no.7 s.361
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• pp.45-53
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• 2007

In this paper, we propose an efficient hardware architecture for H.264/AVC CAVLC (Context-based Adaptive Variable Length Coding) encoding. Previous CAVLC architectures search all of the coefficients to find statistic characteristics in a block. However, it is unnecessary information that zero coefficients following the last position of a non-zero coefficient when CAVLC encodes residual coefficients. In order to reduce this unnecessary operation, we propose two techniques, which detect the first and last position of non-zero coefficients and arrange non-zero coefficients sequentially. By adopting these two techniques, the required processing time was reduced about 23% compared with previous architecture. It was designed in a hardware description language and total logic gate count is 16.3k using 0.18um standard cell library Simulation results show that our design is capable of real-time processing for $1920{\times}1088\;30fps$ videos at 81MHz.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• v.2
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• pp.15-22
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• 2006

This paper presents a novel signal tracking algorithm for GNSS receivers using a MLE technique. In order to perform a robust signal tracking in severe signal environments, e.g., high dynamics for navigation vehicles or weak signals for indoor positioning, the MLE based signal tracking approach is adopted in the paper. With assuming white Gaussian additive noise, the cost function of MLE is expanded to the cost function of NLSE. Efficient and practical approach for Doppler frequency tracking by the MLE is derived based on the assumption of code-free signals, i.e., the cost function of the MLE for carrier Doppler tracking is used to derive a discriminator function to create error signals from incoming and reference signals. The use of the MLE method for carrier tracking makes it possible to generalize the MLE equation for arbitrary codes and modulation schemes. This is ideally suited for various GNSS signals with same structure of tracking module. This paper proposes two different types of MLE based tracking method, i.e., an iterative batch processing method and a non-iterative feed-forward processing method. The first method is derived without any limitation on time consumption, while the second method is proposed for a time limited case by using a 1st derivative of cost function, which is proportional to error signal from discriminators of conventional tracking methods. The second method can be implemented by a block diagram approach for tracking carrier phase, Doppler frequency and code phase with assuming no correlation of signal parameters. Finally, a state space form of FLL/PLL/DLL is adopted to the designed MLE based tracking algorithm for reducing noise on the estimated signal parameters.

• The Transactions of the Korea Information Processing Society
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• v.7 no.10
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• pp.3138-3147
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• 2000

EC(Electronic Commerce) which is cone the virtual space through Internet, has the advantage of time and space. On the contrary, it also has weak point like security probelm because anybody can easily access to the system due to open network attribute of Internet. Theretore, we need the solutions that protect the EC security problem for safe and useful EC activity. One of these solution is the implemonlation of a strong cipher algorithm. YK2(YoungKu Kang) cipher algorithm proposed in this paper is advantage for the EC security and it overcomes the limit of the current 6/1 bits block cipher algorithm using 128 bits key length for input, output, encryption key and 32 rounds. Moreover, it is degigned for the increase of time complexity and probability calculation by adapting more complex design for key scheduling regarded as one of the important element effected to enciyption.

• Journal of the Institute of Convergence Signal Processing
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• v.5 no.3
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• pp.230-235
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• 2004

This paper describes FPGA implementation of a pointer interpreter which can support a synchronization of SDH(or SONET)-based transmission network. The pointer interpreter consists of a pointer-word extractor and a pointer-word interpreter The pointer-word extractor which is composed of mod-6480 counter, shift register and pointer synchronizing block, finds out the H1 and H2 pointer word from a 51.84 Mb/s AU-3/STS-1 data frame and then performs the synchronizing with a 6.48 Mb/s by dividing them in 8. Based on the extracted pointer word, pointer-word interpreter analyzes pointer states such LOP, AIS and NORM according to pointer state-transition algorithm. It consists of a majority vote, a pointer word valid/invalid check, a pointer justification, and a pointer state check. The simulation results of Xilinx Virtex XCV200PQ240 FPGA chip shows the exact pointer word extraction and correct decision of pointer status based on extracted pointer word. The proposed pointer interpreter is suitable for pointer interpretation of 155 Mb/s STM-1/STS-3 frame.

• Journal of Satellite, Information and Communications
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• v.5 no.1
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• pp.32-37
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• 2010

The algorithm of multiple channel signal processing requires the flexibility of variable frequency band, efficient allocation of transmission power, and flexible frequency band reallocation to satisfy various service types which requires different transmission rates and frequency band. There are three methods including per-channel approach, multiple tree approach, and block approach performing frequency band reallocation method by channelization and dechannelization in the multiple-channel signal. This paper proposes an improved per-channel approach for converting the frequency band of multiple carrier signals efficiently. The proposed algorithm performs decimation and interpolation using CIC(cascaded integrator comb filter), half-band filter, and FIR filter. In addition, it performs filtering of each sub-channel, and reallocates channel band through FIR low-pass filter in the multiple-channel signal. The computer simulation result shows that the perfect reconstruction of output signal and the flexible frequency band reallocation is performed efficiently by the proposed algorithm.

• The Transactions of the Korea Information Processing Society
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• v.6 no.2
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• pp.274-281
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• 1999

Many popularly used recent high-sped and high-capacity disks use the Zone-Structured in which a disk consists of multiple zones. A zone-structured disk has multiple zones, and the bandwidth and the number of sectors in each zone are different from each other. When the previous studies that modeled disks based on the assumption that the number of sectors in all tracks are same are applied to the zone-structured disk and the video data stored in a round-robin manner are read out with the SCAN technique, the transfer rate of the disk is fixed with that of the innermost zone. And excessive disk space is wasted either. To resolve the problem, this paper proposes a method for reconstructing the physical zones into logical zones by split and merge operations and develops a method for determining optimum transfer block size.

• Journal of Biomedical Engineering Research
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• v.19 no.2
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• pp.113-118
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• 1998

By their rapid and periodic actions, the cilia of the human respiratory tract play an important role in clearing inhaled noxious particles. Based on the automated image-processing technique, we studied the method analyzing ciliary beat frequency (CBF) objectively and quantitatively. Microscopic ciliary images were transformed into digitized gray ones through an image-grabber, and from these we extracted signals for CBF. By means of a FFT, maximum peak frequencies were detected as CBFs in each partitioned block for the entire digitized field. With these CBFs, we composed distribution maps visually showing the spatial distribution of CBFs. Through distribution maps of CBF, the whole aspects of CBF changes for cells and the difference of CBF of neighboring cells can be easily measured and detected. Histogram statistics calculated from the user-defined polygonal window can show the local dominant frequency presumed to be the CBF of a cell or a crust the region includes.